ATE439371T1 - Synthese von peptid t-1249 mit peptidzwischenproduktfragmenten - Google Patents
Synthese von peptid t-1249 mit peptidzwischenproduktfragmentenInfo
- Publication number
- ATE439371T1 ATE439371T1 AT05821840T AT05821840T ATE439371T1 AT E439371 T1 ATE439371 T1 AT E439371T1 AT 05821840 T AT05821840 T AT 05821840T AT 05821840 T AT05821840 T AT 05821840T AT E439371 T1 ATE439371 T1 AT E439371T1
- Authority
- AT
- Austria
- Prior art keywords
- peptide
- synthesis
- intermediate fragments
- peptide intermediates
- fragments
- Prior art date
Links
- 108010037251 peptide T1249 Proteins 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000012634 fragment Substances 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- ZFEAMMNVDPDEGE-LGRGJMMZSA-N tifuvirtide Chemical compound C([C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(C)=O)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)C1=CC=C(O)C=C1 ZFEAMMNVDPDEGE-LGRGJMMZSA-N 0.000 title 1
- 239000000543 intermediate Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000010532 solid phase synthesis reaction Methods 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64071604P | 2004-12-30 | 2004-12-30 | |
| PCT/EP2005/013854 WO2006069729A1 (en) | 2004-12-30 | 2005-12-22 | Synthesis of peptide t-1249 using peptide intermediate fragments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE439371T1 true ATE439371T1 (de) | 2009-08-15 |
Family
ID=36001047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05821840T ATE439371T1 (de) | 2004-12-30 | 2005-12-22 | Synthese von peptid t-1249 mit peptidzwischenproduktfragmenten |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7544665B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1856142B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4886703B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101133076B (cg-RX-API-DMAC7.html) |
| AT (1) | ATE439371T1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2593866C (cg-RX-API-DMAC7.html) |
| DE (1) | DE602005016024D1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2329270T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006069729A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007007917A (es) * | 2004-12-30 | 2007-08-14 | Hoffmann La Roche | Sintesis del peptido t-20 utilizando fragmentos peptidicos intermediarios. |
| CA2703113A1 (en) * | 2007-10-27 | 2009-04-30 | F. Hoffmann-La Roche Ag | Insulinotropic peptide synthesis using solid and solution phase combination techniques |
| CA2707132A1 (en) * | 2007-12-11 | 2009-06-18 | F. Hoffmann-La Roche Ag | Insulinotropic peptide synthesis using solid and solution phase combination techniques |
| DE102008017645A1 (de) | 2008-04-04 | 2009-10-08 | Carl Zeiss Smt Ag | Vorrichtung zur mikrolithographischen Projektionsbelichtung sowie Vorrichtung zur Inspektion einer Oberfläche eines Substrats |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4010560B2 (ja) | 1992-07-20 | 2007-11-21 | ドューク ユニバーシティー | Ｈｉｖ複製を阻害する化合物 |
| US6281335B1 (en) | 1993-10-08 | 2001-08-28 | Coulter Corporation | Hybridoma and anti-KC-4 humanized monoclonal antibody |
| US6479055B1 (en) | 1993-06-07 | 2002-11-12 | Trimeris, Inc. | Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission |
| US5464933A (en) | 1993-06-07 | 1995-11-07 | Duke University | Synthetic peptide inhibitors of HIV transmission |
| US6281331B1 (en) * | 1998-03-23 | 2001-08-28 | Trimeris, Inc. | Methods and compositions for peptide synthesis |
| US6469136B1 (en) * | 1999-07-07 | 2002-10-22 | Trimeris, Inc. | Methods and composition for peptide synthesis |
| US20040209999A1 (en) * | 2002-08-16 | 2004-10-21 | Bohling James Charles | Method of manufacturing polypeptides, including T-20 and T-1249, at commercial scale, and polypeptide compositions related thereto |
| AU2004200485A1 (en) * | 2003-02-25 | 2004-09-09 | Rohm And Haas Company | Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto |
| MX2007007917A (es) | 2004-12-30 | 2007-08-14 | Hoffmann La Roche | Sintesis del peptido t-20 utilizando fragmentos peptidicos intermediarios. |
-
2005
- 2005-12-22 CA CA2593866A patent/CA2593866C/en not_active Expired - Fee Related
- 2005-12-22 WO PCT/EP2005/013854 patent/WO2006069729A1/en not_active Ceased
- 2005-12-22 JP JP2007548733A patent/JP4886703B2/ja not_active Expired - Fee Related
- 2005-12-22 DE DE602005016024T patent/DE602005016024D1/de not_active Expired - Lifetime
- 2005-12-22 ES ES05821840T patent/ES2329270T3/es not_active Expired - Lifetime
- 2005-12-22 EP EP05821840A patent/EP1856142B1/en not_active Expired - Lifetime
- 2005-12-22 CN CN2005800488419A patent/CN101133076B/zh not_active Expired - Fee Related
- 2005-12-22 AT AT05821840T patent/ATE439371T1/de not_active IP Right Cessation
- 2005-12-30 US US11/322,394 patent/US7544665B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7544665B2 (en) | 2009-06-09 |
| JP2008526699A (ja) | 2008-07-24 |
| CA2593866C (en) | 2013-08-06 |
| CN101133076A (zh) | 2008-02-27 |
| ES2329270T3 (es) | 2009-11-24 |
| CA2593866A1 (en) | 2006-07-06 |
| CN101133076B (zh) | 2011-07-13 |
| US20060173163A1 (en) | 2006-08-03 |
| DE602005016024D1 (de) | 2009-09-24 |
| EP1856142A1 (en) | 2007-11-21 |
| WO2006069729A1 (en) | 2006-07-06 |
| JP4886703B2 (ja) | 2012-02-29 |
| EP1856142B1 (en) | 2009-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |