ES2326307T3 - Combinacion de un inhibidor del receptor abl, receptor pdgf y/o receptor de kit de la tirosina quinasa con un compuesto organico capaz de unirse a la glicoproteina acida-alfa1. - Google Patents

Combinacion de un inhibidor del receptor abl, receptor pdgf y/o receptor de kit de la tirosina quinasa con un compuesto organico capaz de unirse a la glicoproteina acida-alfa1. Download PDF

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Publication number
ES2326307T3
ES2326307T3 ES00985244T ES00985244T ES2326307T3 ES 2326307 T3 ES2326307 T3 ES 2326307T3 ES 00985244 T ES00985244 T ES 00985244T ES 00985244 T ES00985244 T ES 00985244T ES 2326307 T3 ES2326307 T3 ES 2326307T3
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ES
Spain
Prior art keywords
abl
salt
receptor
pdgf
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00985244T
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English (en)
Spanish (es)
Inventor
Carlo Gambacorti-Passerini
Philipp Lecoutre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
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Filing date
Publication date
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Publication of ES2326307T3 publication Critical patent/ES2326307T3/es
Anticipated expiration legal-status Critical
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES00985244T 1999-12-27 2000-12-22 Combinacion de un inhibidor del receptor abl, receptor pdgf y/o receptor de kit de la tirosina quinasa con un compuesto organico capaz de unirse a la glicoproteina acida-alfa1. Expired - Lifetime ES2326307T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI99A2711 1999-12-27
IT1999MI002711A ITMI992711A1 (it) 1999-12-27 1999-12-27 Composti organici

Publications (1)

Publication Number Publication Date
ES2326307T3 true ES2326307T3 (es) 2009-10-07

Family

ID=11384195

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00985244T Expired - Lifetime ES2326307T3 (es) 1999-12-27 2000-12-22 Combinacion de un inhibidor del receptor abl, receptor pdgf y/o receptor de kit de la tirosina quinasa con un compuesto organico capaz de unirse a la glicoproteina acida-alfa1.

Country Status (18)

Country Link
US (2) US20030125343A1 (https=)
EP (1) EP1250140B1 (https=)
JP (1) JP2003523325A (https=)
CN (1) CN1304005C (https=)
AR (1) AR030179A1 (https=)
AT (1) ATE432069T1 (https=)
AU (1) AU2171901A (https=)
BR (1) BR0016817A (https=)
CA (1) CA2394944A1 (https=)
CO (1) CO5271710A1 (https=)
DE (1) DE60042283D1 (https=)
ES (1) ES2326307T3 (https=)
HK (1) HK1050993A1 (https=)
IT (1) ITMI992711A1 (https=)
PE (1) PE20010991A1 (https=)
PT (1) PT1250140E (https=)
TW (1) TWI246917B (https=)
WO (1) WO2001047507A2 (https=)

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GB0201508D0 (en) 2002-01-23 2002-03-13 Novartis Ag Organic compounds
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GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
WO2004026930A2 (en) * 2002-06-26 2004-04-01 The Ohio State University Research Foundation The method for reducing inflammation using sti-571 or its salt
JP2005533838A (ja) * 2002-07-24 2005-11-10 ノバルティス　アクチエンゲゼルシャフト 未分化甲状腺癌を処置するための４−（４−メチルピペラジン−１−イルメチル）−ｎ−［４−メチル−３−（４−ピリジン−３−イル）ピリミジン−２−イルアミノ］フェニル］−ベンズアミド
DE60313339T2 (de) * 2002-07-31 2008-01-03 Critical Outcome Technologies, Inc. Protein tyrosin kinase inhibitoren
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US7629347B2 (en) * 2002-10-09 2009-12-08 Critical Outcome Technologies, Inc. Protein tyrosine kinase inhibitors
AU2003268185A1 (en) * 2003-08-25 2005-04-11 Dana-Farber Cancer Institute Inc. Method of treating mixed lineage leukemia gene-rearranged acute lymphoblastic leukemias
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TW200517114A (en) * 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
DK1720853T3 (en) † 2004-02-11 2016-03-29 Natco Pharma Ltd HIS UNKNOWN POLYMORPH FORM OF IMATINIBMYLYLATE AND PROCEDURE FOR PREPARING IT
MXPA06015237A (es) 2004-06-29 2007-12-10 Amgen Inc Pirrolo[2-3-d]pirimidinas que modulan la actividad de ack1 y lck.
JP2008508358A (ja) * 2004-08-02 2008-03-21 オーエスアイ・ファーマスーティカルズ・インコーポレーテッド アリール−アミノ置換ピロロピリミジンマルチキナーゼ阻害化合物
ATE519759T1 (de) 2004-12-30 2011-08-15 Exelixis Inc Pyrimidinderivate als kinasemodulatoren und anwendungsverfahren
US20070059359A1 (en) * 2005-06-07 2007-03-15 Thomas Backensfeld Immediate-release and high-drug-load pharmaceutical formulations of non-micronised (4-chlorophenyl)[4-(4-pyridylmethyl)phthalazin-1-yl] and salts thereof
US20060275365A1 (en) * 2005-06-07 2006-12-07 Thomas Backensfeld Immediate-release and high-drug-load pharmaceutical formulations of micronised (4-chlorophenyl) [4-(4-pyridylmethyl)phthalazin-1-yl] and salts thereof
DE602006015994D1 (de) * 2005-06-23 2010-09-16 Novartis Ag Verfahren zur behandlung von soliden tumoren einschliesslich der verabreichung einer kombination mit imatinib und einem effluxpumpenhemmer
EP1979349B1 (en) * 2005-12-21 2010-07-28 Abbott Laboratories Anti-viral compounds
US7910595B2 (en) * 2005-12-21 2011-03-22 Abbott Laboratories Anti-viral compounds
WO2007081517A2 (en) 2005-12-21 2007-07-19 Abbott Laboratories Anti-viral compounds
CA2649755C (en) * 2006-04-20 2014-12-02 Janssen Pharmaceutica N.V. Method of inhibiting c-kit kinase
EP2043651A2 (en) * 2006-07-05 2009-04-08 Exelixis, Inc. Methods of using igf1r and abl kinase modulators
US8236950B2 (en) 2006-12-20 2012-08-07 Abbott Laboratories Anti-viral compounds
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ITRM20090578A1 (it) * 2009-11-10 2011-05-11 Noi Per Voi Onlus Nuove composizioni per il trattamento di leucemie chemioresistenti e/o di leucemie potenzialmente chemioresistenti.
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US20120115878A1 (en) 2010-11-10 2012-05-10 John Vincent Calienni Salt(s) of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7h-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide and processes of making thereof
TR201010618A2 (tr) * 2010-12-20 2012-07-23 Bi̇lgi̇ç Mahmut İmatinib içeren bir oral dozaj formu ve bu oral dozaj formunun üretimi
PL394169A1 (pl) 2011-03-09 2012-09-10 Adamed Spółka Z Ograniczoną Odpowiedzialnością Kompozycja farmaceutyczna metanosulfonianu imatinibu do napełniania jednostkowych postaci dawkowania oraz sposób jej wytwarzania
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Also Published As

Publication number Publication date
US20090221519A1 (en) 2009-09-03
BR0016817A (pt) 2002-10-01
CN1414858A (zh) 2003-04-30
ITMI992711A0 (it) 1999-12-27
CO5271710A1 (es) 2003-04-30
EP1250140A2 (en) 2002-10-23
ITMI992711A1 (it) 2001-06-27
US20030125343A1 (en) 2003-07-03
AR030179A1 (es) 2003-08-13
PT1250140E (pt) 2009-08-24
DE60042283D1 (de) 2009-07-09
TWI246917B (en) 2006-01-11
CA2394944A1 (en) 2001-07-05
HK1050993A1 (zh) 2003-07-18
WO2001047507A3 (en) 2002-04-04
ATE432069T1 (de) 2009-06-15
CN1304005C (zh) 2007-03-14
EP1250140B1 (en) 2009-05-27
PE20010991A1 (es) 2001-10-23
WO2001047507A2 (en) 2001-07-05
AU2171901A (en) 2001-07-09
JP2003523325A (ja) 2003-08-05

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