ES2323310T5 - Método de preparación de una composición nutritiva que comprende ácido láctico L(+) - Google Patents
Método de preparación de una composición nutritiva que comprende ácido láctico L(+) Download PDFInfo
- Publication number
- ES2323310T5 ES2323310T5 ES03795909.5T ES03795909T ES2323310T5 ES 2323310 T5 ES2323310 T5 ES 2323310T5 ES 03795909 T ES03795909 T ES 03795909T ES 2323310 T5 ES2323310 T5 ES 2323310T5
- Authority
- ES
- Spain
- Prior art keywords
- lactic acid
- composition
- nutritional composition
- preparing
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 title description 34
- 239000000203 mixture Substances 0.000 title description 21
- 239000004310 lactic acid Substances 0.000 title description 16
- 235000014655 lactic acid Nutrition 0.000 title description 16
- 235000016709 nutrition Nutrition 0.000 title description 7
- 238000000034 method Methods 0.000 title description 3
- 241000894006 Bacteria Species 0.000 description 10
- 102000004169 proteins and genes Human genes 0.000 description 7
- 108090000623 proteins and genes Proteins 0.000 description 7
- 238000000855 fermentation Methods 0.000 description 5
- 230000004151 fermentation Effects 0.000 description 5
- 239000000843 powder Substances 0.000 description 4
- 108020004414 DNA Proteins 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 239000002207 metabolite Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 108020000946 Bacterial DNA Proteins 0.000 description 1
- 239000003298 DNA probe Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pediatric Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Dairy Products (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Beans For Foods Or Fodder (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Description
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E03795909
17-03-2015
Como consecuencia, de acuerdo con un primer aspecto, la presente invención da a conocer un método según la reivindicación 1.
Una ventaja de la presente invención es que la composición preparada según la reivindicación 1 muestra actividad bacteriostática y se puede evitar una etapa de fermentación.
Otra ventaja de la presente invención es que da a conocer una composición nutritiva acidificada que puede fabricarse con rapidez.
Descripción detallada de la invención
Dentro del contexto de esta descripción la palabra “comprende” se considera que significa “incluye, entre otras cosas”. No está destinada a ser interpretada como “comprende solamente”.
Dentro del contexto de la presente invención el ácido láctico L(+) se comprende como un equivalente del ácido S (+)2-hidroxipropiónico.
El término “acidificado de forma directa” se refiere al hecho de que el ácido es añadido de manera directa a la composición nutritiva durante su preparación. La acidez del ácido láctico L(+) no se obtiene por un proceso de fermentación de la composición, en la que las bacterias del ácido láctico producen el ácido láctico y la composición es acidificada de modo continuo a lo largo de un periodo de tiempo de 2-10 horas usualmente.
El término “fuente de proteínas” no está destinado a ser interpretado como incluyendo solamente proteínas, sino que incluye cualquier materia proteinogénica, es decir, puede ser utilizada por el cuerpo humano o animal para sintetizar proteínas. Como ejemplos, además de proteínas intactas, se pueden citar proteínas hidrolizadas y aminoácidos libres.
Todos los porcentajes son porcentajes en peso, si no se indica de otro modo.
El hecho de que la composición sea acidificada de forma directa puede ser determinado fácilmente por métodos analíticos que detectan la presencia de bacterias vivas o muertas de ácido láctico o la presencia de metabolitos de dichas bacterias acidificantes.
Por ejemplo, un análisis cuantitativo del ADN puede ser adecuado para determinar si la composición ha sido fermentada por una bacteria de ácido láctico o acidificada de forma directa. Sondas de ADN específicas de especies de bacterias de ácido láctico han sido descritas en la bibliografía científica y se pueden concebir y utilizar fácilmente por los técnicos de la materia.
Si la composición nutritiva comprende ADN bacteriano de una bacteria de fermentación en cantidades superiores al ADN que corresponde a 105 bacterias/g de composición (materia seca), la composición ha sido fermentada.
Otros métodos para determinar si una composición nutritiva ha sido sometida a un proceso de fermentación pueden ser seleccionados dependiendo de los ingredientes restantes de la composición nutritiva. Por ejemplo, aminoácidos libres individuales, pequeños péptidos y/o nitrógeno no proteínico pueden ser determinados si la composición se basa en proteínas intactas, porque la actividad de las bacterias fermentantes de ácido láctico cambia la composición de estos compuestos.
Los aminoácidos libres, péptidos y otros metabolitos son habitualmente específicos para la actividad de fermentación
o metabolismo de una cepa específica de bacterias fermentantes y la presencia de estos metabolitos se tiene que analizar después de haber determinado por análisis de ADN, por ejemplo, cual es la bacteria de ácido láctico que ha fermentado la composición.
Para una composición en polvo, el término “en estado líquido” se refiere a la composición líquida, hidratada o reconstituida nutritiva obtenida usualmente añadiendo una cantidad predeterminada de agua o una cantidad predeterminada de composición en polvo. Habitualmente, las cantidades de agua y/o de material en polvo son específicas para la composición en polvo determinada.
Con respecto al ácido láctico total de la composición nutritiva el ácido láctico L(+) se encuentra predominantemente presente con el significado de que se encuentra presente en forma de L(+) un mínimo del 70%, preferiblemente un mínimo de 80%, más preferiblemente un mínimo de 90% o incluso más preferentemente un mínimo de 95% en peso de ácido láctico. Por ejemplo, 96%, 97%, 98% o 99% del ácido láctico total se encuentra presente en forma de ácido láctico L(+).
Los términos ácido láctico L(+) “aislado” o “purificado” se refieren al ácido láctico en el que se encuentra presente el enantiómero L(+) en relación con el otro enantiómero del ácido láctico, en los porcentajes en peso que se han indicado en lo anterior.
3
Claims (1)
-
imagen1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02028285 | 2002-12-17 | ||
| EP02028285 | 2002-12-17 | ||
| PCT/EP2003/014400 WO2004054371A2 (en) | 2002-12-17 | 2003-12-17 | Nutritional formula comprising l(+) lactic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2323310T3 ES2323310T3 (es) | 2009-07-13 |
| ES2323310T5 true ES2323310T5 (es) | 2015-04-06 |
Family
ID=32338026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03795909.5T Expired - Lifetime ES2323310T5 (es) | 2002-12-17 | 2003-12-17 | Método de preparación de una composición nutritiva que comprende ácido láctico L(+) |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US20060078649A1 (es) |
| EP (1) | EP1575377B2 (es) |
| JP (1) | JP4376790B2 (es) |
| KR (1) | KR20050088450A (es) |
| CN (1) | CN100339021C (es) |
| AP (1) | AP2005003329A0 (es) |
| AR (1) | AR042491A1 (es) |
| AT (1) | ATE428313T1 (es) |
| AU (1) | AU2003298196B2 (es) |
| BR (1) | BR0317386B1 (es) |
| CA (1) | CA2510268C (es) |
| DE (1) | DE60327253D1 (es) |
| DK (1) | DK1575377T3 (es) |
| EA (1) | EA009071B1 (es) |
| ES (1) | ES2323310T5 (es) |
| HK (1) | HK1083727A1 (es) |
| MX (1) | MXPA05006410A (es) |
| MY (1) | MY140883A (es) |
| NO (1) | NO20053462L (es) |
| NZ (1) | NZ540864A (es) |
| OA (1) | OA12974A (es) |
| PT (1) | PT1575377E (es) |
| RU (1) | RU2005122508A (es) |
| TW (1) | TWI364260B (es) |
| WO (1) | WO2004054371A2 (es) |
| ZA (1) | ZA200505679B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1972207B1 (en) * | 2007-03-21 | 2018-02-28 | Nestec S.A. | Safety System For Powdered Nutritional Compositions |
| WO2008144145A1 (en) * | 2007-05-18 | 2008-11-27 | Mead Johnson Nutrition Company | Acidified liquid human milk supplement |
| BRPI0820304A2 (pt) | 2007-11-07 | 2017-05-23 | Mead Johnson Nutrition Co | processo para diminuir o amargor e melhorar o sabor de fórmulas infantis livres de proteína e hidrolisadas |
| CN101925307B (zh) | 2007-12-05 | 2013-02-13 | 荷兰纽迪希亚公司 | 高能量液体肠营养组合物 |
| WO2009113845A1 (en) | 2008-03-12 | 2009-09-17 | N.V. Nutricia | High protein liquid enteral nutritional composition |
| US8498729B2 (en) * | 2008-08-29 | 2013-07-30 | Smp Logic Systems Llc | Manufacturing execution system for use in manufacturing baby formula |
| EP2168444A1 (en) * | 2008-09-24 | 2010-03-31 | Nestec S.A. | Acidified nutritional formula |
| MX2011004141A (es) | 2008-10-17 | 2011-05-24 | Nestec Sa | Composiciones de proteina de suero lacteo, metodos y usos. |
| FR2968895B1 (fr) * | 2010-12-17 | 2013-04-12 | United Pharmaceuticals | Composition anti-regurgitation et/ou anti-reflux gastro-oesophagien, preparation et utilisations |
| JP6171364B2 (ja) * | 2012-01-31 | 2017-08-02 | 日本新薬株式会社 | 高タンパク液状栄養食品組成物 |
| WO2013129912A1 (en) * | 2012-02-28 | 2013-09-06 | N.V. Nutricia | Energy-rich liquid nutritional composition having improved organoleptic properties |
| US20150305384A1 (en) * | 2014-04-25 | 2015-10-29 | Mead Johnson Nutrition Company | Pediatric nutritional composition with human milk oligosaccahrides, prebiotics and probiotics |
| BR112016027950B1 (pt) | 2014-06-25 | 2021-11-23 | Société des Produits Nestlé S.A. | Blenda láctea líquida, seu uso e seu método de produção |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4212893A (en) * | 1978-02-10 | 1980-07-15 | Honey Bee Corporation | Acidified whole milk beverage and method of preparation |
| US4303692A (en) * | 1978-11-22 | 1981-12-01 | Gaull Gerald E | Infant milk formula |
| MX9707584A (es) * | 1995-04-07 | 1998-02-28 | Abbott Lab | Complementos de calcio y bebidas que contienen calcio y que comprenden vitamina d. |
| US6475539B1 (en) * | 1998-05-07 | 2002-11-05 | Abbott Laboratories | Nutritionally complete low pH enteral formula |
-
2003
- 2003-12-16 MY MYPI20034826A patent/MY140883A/en unknown
- 2003-12-16 AR ARP030104658A patent/AR042491A1/es unknown
- 2003-12-17 ES ES03795909.5T patent/ES2323310T5/es not_active Expired - Lifetime
- 2003-12-17 MX MXPA05006410A patent/MXPA05006410A/es active IP Right Grant
- 2003-12-17 EP EP03795909.5A patent/EP1575377B2/en not_active Expired - Lifetime
- 2003-12-17 OA OA1200500184A patent/OA12974A/en unknown
- 2003-12-17 TW TW092135828A patent/TWI364260B/zh not_active IP Right Cessation
- 2003-12-17 CA CA2510268A patent/CA2510268C/en not_active Expired - Fee Related
- 2003-12-17 US US10/539,092 patent/US20060078649A1/en not_active Abandoned
- 2003-12-17 DE DE60327253T patent/DE60327253D1/de not_active Expired - Lifetime
- 2003-12-17 AT AT03795909T patent/ATE428313T1/de not_active IP Right Cessation
- 2003-12-17 JP JP2004560455A patent/JP4376790B2/ja not_active Expired - Fee Related
- 2003-12-17 NZ NZ540864A patent/NZ540864A/en unknown
- 2003-12-17 AU AU2003298196A patent/AU2003298196B2/en not_active Ceased
- 2003-12-17 DK DK03795909T patent/DK1575377T3/da active
- 2003-12-17 CN CNB200380106392XA patent/CN100339021C/zh not_active Expired - Fee Related
- 2003-12-17 RU RU2005122508/13A patent/RU2005122508A/ru not_active Application Discontinuation
- 2003-12-17 PT PT03795909T patent/PT1575377E/pt unknown
- 2003-12-17 AP AP2005003329A patent/AP2005003329A0/xx unknown
- 2003-12-17 EA EA200500989A patent/EA009071B1/ru not_active IP Right Cessation
- 2003-12-17 KR KR1020057011401A patent/KR20050088450A/ko not_active Application Discontinuation
- 2003-12-17 WO PCT/EP2003/014400 patent/WO2004054371A2/en active Application Filing
- 2003-12-17 BR BRPI0317386-0A patent/BR0317386B1/pt not_active IP Right Cessation
-
2005
- 2005-07-14 ZA ZA200505679A patent/ZA200505679B/xx unknown
- 2005-07-15 NO NO20053462A patent/NO20053462L/no not_active Application Discontinuation
-
2006
- 2006-03-27 HK HK06103798A patent/HK1083727A1/xx not_active IP Right Cessation
-
2012
- 2012-06-22 US US13/531,107 patent/US20120269943A1/en not_active Abandoned
-
2014
- 2014-05-27 US US14/287,903 patent/US20140272093A1/en not_active Abandoned
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