ES2277149T3 - Derivados de piridina como moduladores de los receptores cb2. - Google Patents

Derivados de piridina como moduladores de los receptores cb2. Download PDF

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Publication number
ES2277149T3
ES2277149T3 ES03798193T ES03798193T ES2277149T3 ES 2277149 T3 ES2277149 T3 ES 2277149T3 ES 03798193 T ES03798193 T ES 03798193T ES 03798193 T ES03798193 T ES 03798193T ES 2277149 T3 ES2277149 T3 ES 2277149T3
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Spain
Prior art keywords
nicotinamide
phenylamino
fluoro
benzyl
isopropyl
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Expired - Lifetime
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ES03798193T
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English (en)
Spanish (es)
Inventor
Andrew John Eatherton
Gerard Martin Paul Giblin
Richard Howard Green Deceased
Karamjit Singh Jandu
William Leonard Mitchell
Alan Naylor
Giovanni C/o NiKem Research S.r.L. PALOMBI
Derek Anthony Rawlings
Brian Peter Slingsby
Andrew Richard Whittington
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Glaxo Group Ltd
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Glaxo Group Ltd
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
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ES03798193T 2002-09-27 2003-09-25 Derivados de piridina como moduladores de los receptores cb2. Expired - Lifetime ES2277149T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0222495 2002-09-27
GBGB0222495.4A GB0222495D0 (en) 2002-09-27 2002-09-27 Compounds

Publications (1)

Publication Number Publication Date
ES2277149T3 true ES2277149T3 (es) 2007-07-01

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ES03798193T Expired - Lifetime ES2277149T3 (es) 2002-09-27 2003-09-25 Derivados de piridina como moduladores de los receptores cb2.

Country Status (9)

Country Link
US (1) US20070129367A1 (enExample)
EP (1) EP1562907B1 (enExample)
JP (1) JP2006508065A (enExample)
AT (1) ATE345329T1 (enExample)
AU (1) AU2003276028A1 (enExample)
DE (1) DE60309739T2 (enExample)
ES (1) ES2277149T3 (enExample)
GB (1) GB0222495D0 (enExample)
WO (1) WO2004029027A1 (enExample)

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EP1492784A4 (en) 2002-03-28 2006-03-29 Merck & Co Inc SUBSTITUTED 2,3-DIPHENYLPYRIDINES
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TW200505902A (en) 2003-03-20 2005-02-16 Schering Corp Cannabinoid receptor ligands
US7932272B2 (en) 2003-09-30 2011-04-26 Eisai R&D Management Co., Ltd. Antifungal agent containing heterocyclic compound
GB0402356D0 (en) * 2004-02-03 2004-03-10 Glaxo Group Ltd Novel compounds
GB0402355D0 (en) * 2004-02-03 2004-03-10 Glaxo Group Ltd Novel compounds
GB0402357D0 (en) * 2004-02-03 2004-03-10 Glaxo Group Ltd Novel compounds
WO2006106711A1 (ja) 2005-03-30 2006-10-12 Eisai R & D Management Co., Ltd. ピリジン誘導体を含有する抗真菌剤
JPWO2006129609A1 (ja) * 2005-05-30 2009-01-08 塩野義製薬株式会社 ２−ナフチルイミノ−５，５−ジ置換−１，３−チアジン誘導体
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
JP2009536613A (ja) * 2006-04-07 2009-10-15 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｂ２受容体を調節する化合物
WO2008014199A2 (en) 2006-07-28 2008-01-31 Boehringer Ingelheim International Gmbh Sulfonyl compounds which modulate the cb2 receptor
WO2008035726A1 (en) 2006-09-21 2008-03-27 Eisai R & D Management Co., Ltd. Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same
KR20090069318A (ko) 2006-09-25 2009-06-30 베링거 인겔하임 인터내셔날 게엠베하 Ｃｂ2 수용체를 조절하는 화합물
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US20070129367A1 (en) 2007-06-07
GB0222495D0 (en) 2002-11-06
JP2006508065A (ja) 2006-03-09
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EP1562907A1 (en) 2005-08-17
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