ES2229783T3 - Dispositivos para proporcionar una terapia faramaceutica prolongada. - Google Patents
Dispositivos para proporcionar una terapia faramaceutica prolongada.Info
- Publication number
- ES2229783T3 ES2229783T3 ES99955212T ES99955212T ES2229783T3 ES 2229783 T3 ES2229783 T3 ES 2229783T3 ES 99955212 T ES99955212 T ES 99955212T ES 99955212 T ES99955212 T ES 99955212T ES 2229783 T3 ES2229783 T3 ES 2229783T3
- Authority
- ES
- Spain
- Prior art keywords
- drug
- layer
- release
- dosage form
- form according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 229940068196 placebo Drugs 0.000 description 1
- 229920001993 poloxamer 188 Polymers 0.000 description 1
- 229940044519 poloxamer 188 Drugs 0.000 description 1
- 229920000307 polymer substrate Polymers 0.000 description 1
- 229910000160 potassium phosphate Inorganic materials 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 235000011008 sodium phosphates Nutrition 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000001975 sympathomimetic effect Effects 0.000 description 1
- 229940064707 sympathomimetics Drugs 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 239000003204 tranquilizing agent Substances 0.000 description 1
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- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
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- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/88—Investigating the presence of flaws or contamination
- G01N21/95—Investigating the presence of flaws or contamination characterised by the material or shape of the object to be examined
- G01N21/9508—Capsules; Tablets
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Psychology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8778798P | 1998-06-03 | 1998-06-03 | |
| US87787P | 1998-06-03 | ||
| US09/253,317 US6919373B1 (en) | 1996-11-12 | 1999-02-19 | Methods and devices for providing prolonged drug therapy |
| US253317 | 1999-02-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2229783T3 true ES2229783T3 (es) | 2005-04-16 |
Family
ID=26777397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99955212T Expired - Lifetime ES2229783T3 (es) | 1998-06-03 | 1999-05-27 | Dispositivos para proporcionar una terapia faramaceutica prolongada. |
Country Status (16)
| Country | Link |
|---|---|
| EP (2) | EP1449524A1 (enExample) |
| JP (1) | JP2002516848A (enExample) |
| KR (1) | KR20080083074A (enExample) |
| CN (1) | CN1209098C (enExample) |
| AT (1) | ATE277594T1 (enExample) |
| AU (1) | AU4319799A (enExample) |
| CA (1) | CA2333688A1 (enExample) |
| DE (1) | DE69920689T2 (enExample) |
| DK (1) | DK1083879T3 (enExample) |
| ES (1) | ES2229783T3 (enExample) |
| HK (1) | HK1046638B (enExample) |
| IL (1) | IL140020A0 (enExample) |
| NO (1) | NO330235B1 (enExample) |
| NZ (1) | NZ508567A (enExample) |
| PT (1) | PT1083879E (enExample) |
| WO (1) | WO1999062496A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5837284A (en) | 1995-12-04 | 1998-11-17 | Mehta; Atul M. | Delivery of multiple doses of medications |
| US6919373B1 (en) | 1996-11-12 | 2005-07-19 | Alza Corporation | Methods and devices for providing prolonged drug therapy |
| US6962997B1 (en) | 1997-05-22 | 2005-11-08 | Celgene Corporation | Process and intermediates for resolving piperidyl acetamide steroisomers |
| IL142896A0 (en) | 1998-11-02 | 2002-04-21 | Elan Corp Plc | Multiparticulate modified release composition |
| US6673367B1 (en) | 1998-12-17 | 2004-01-06 | Euro-Celtique, S.A. | Controlled/modified release oral methylphenidate formulations |
| US7083808B2 (en) | 1998-12-17 | 2006-08-01 | Euro-Celtique S.A. | Controlled/modified release oral methylphenidate formulations |
| US6419960B1 (en) | 1998-12-17 | 2002-07-16 | Euro-Celtique S.A. | Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations |
| KR20020072290A (ko) * | 2000-01-20 | 2002-09-14 | 델시스 파머수티컬 코포레이션 | 다단계 약물 투여 형태 |
| AR030557A1 (es) | 2000-04-14 | 2003-08-27 | Jagotec Ag | Una tableta en multicapa de liberacion controlada y metodo de tratamiento |
| US20020187192A1 (en) * | 2001-04-30 | 2002-12-12 | Yatindra Joshi | Pharmaceutical composition which reduces or eliminates drug abuse potential |
| US20030049272A1 (en) * | 2001-08-30 | 2003-03-13 | Yatindra Joshi | Pharmaceutical composition which produces irritation |
| US7838026B2 (en) | 2001-09-28 | 2010-11-23 | Mcneil-Ppc, Inc. | Burst-release polymer composition and dosage forms comprising the same |
| MXPA04002973A (es) | 2001-09-28 | 2005-06-20 | Johnson & Johnson | Formas de dosis de liberacion modificada. |
| US7122143B2 (en) | 2001-09-28 | 2006-10-17 | Mcneil-Ppc, Inc. | Methods for manufacturing dosage forms |
| JP4500679B2 (ja) * | 2002-07-29 | 2010-07-14 | アルザ・コーポレーシヨン | パリペリドンを制御送達する方法および投薬形態物 |
| US20050232995A1 (en) * | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
| EP1542662A1 (en) * | 2002-09-28 | 2005-06-22 | McNEIL-PPC, INC. | Immediate release dosage form comprising shell having openings therein |
| GR1004330B (el) * | 2002-10-14 | 2003-09-05 | Lavipharm A.E. | Φαρμακοτεχνικη μορφη για τη χορηγηση οργανικων νιτρικων ενωσεων |
| US7988993B2 (en) | 2002-12-09 | 2011-08-02 | Andrx Pharmaceuticals, Inc. | Oral controlled release dosage form |
| KR20050123097A (ko) * | 2003-02-11 | 2005-12-29 | 알자 코포레이션 | 변형된 층 형상을 갖는 방법 및 제형 |
| KR20060092255A (ko) | 2003-09-26 | 2006-08-22 | 알자 코포레이션 | 고도의 약물적재를 제공하는 약물코팅제 및 그의 제조방법 |
| ATE526988T1 (de) * | 2003-10-08 | 2011-10-15 | Mallinckrodt Llc | Methylphenidat-lösung und relevante verabreichungs- und herstellungsverfahren |
| US7879354B2 (en) | 2004-01-13 | 2011-02-01 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
| EP1755564B1 (en) * | 2004-05-21 | 2013-10-16 | Accu-Break Technologies, Inc. | Immediate release pharmaceutical tablets with height greater than width |
| ES2261006B1 (es) * | 2004-06-10 | 2007-11-01 | Laboratorios Rubio, S.A. | Pellet multicapa de liberacion controlada de metilfenidato. |
| US8541026B2 (en) | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
| WO2006046114A2 (en) * | 2004-10-25 | 2006-05-04 | Ranbaxy Laboratories Limited | Osmotic dosage forms providing ascending drug release, and processes for their preparation |
| WO2009023006A2 (en) * | 2006-05-08 | 2009-02-19 | Mcneil-Ppc, Inc. | Modified release dosage form |
| US8673352B2 (en) | 2005-04-15 | 2014-03-18 | Mcneil-Ppc, Inc. | Modified release dosage form |
| PL116330U1 (en) | 2005-10-31 | 2007-04-02 | Alza Corp | Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation |
| FR2899476B1 (fr) * | 2006-04-11 | 2008-07-04 | Assist Publ Hopitaux De Paris | Association du mazindol dans le traitement du deficit de l'attention/hyperactivite |
| JP2011511782A (ja) | 2008-02-12 | 2011-04-14 | アボット・ラボラトリーズ | 長期放出性ヒドロコドンアセトアミノフェンならびにその関連方法および用途 |
| JP2012508228A (ja) * | 2008-11-07 | 2012-04-05 | サムヤン コーポレイション | メチルフェニデートの放出制御用薬剤学的組成物 |
| AU2010328353B2 (en) | 2009-12-07 | 2015-07-16 | Mcneil-Ppc, Inc. | Partial dip coating of dosage forms for modified release |
| UY34856A (es) * | 2012-07-03 | 2013-12-31 | Bayer Pharma AG | Formas de presentación farmacéuticas que contienen 5-cloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4- morfolinil)-fenil]-1,3-oxazolidin-5-il}-metil)-2-tiofencarboxamida |
| WO2014174388A1 (en) * | 2013-03-29 | 2014-10-30 | Wockhardt Limited | Modified release pharmaceutical compositions of methylphenidate or salts thereof |
| CA3018328A1 (en) | 2014-10-31 | 2016-04-30 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
| US9707217B1 (en) | 2017-02-03 | 2017-07-18 | Osmotica Kereskedelmi Es Szolgaltato Kft | Dose-dumping resistant controlled release dosage form |
| US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
| JP7542539B2 (ja) * | 2019-01-25 | 2024-08-30 | アイアンショア ファーマシューティカルズ アンド ディベロップメント， インコーポレイテッド | 注意欠陥多動性障害を処置するためのメチルフェニデート組成物 |
| WO2020181127A1 (en) * | 2019-03-05 | 2020-09-10 | Kashiv Biosciences, Llc | Delayed release methylphenidate compositions |
| CN114681422B (zh) * | 2020-12-30 | 2023-09-05 | 深圳翰宇药业股份有限公司 | 一种硝苯地平控释片及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4824675A (en) * | 1987-07-13 | 1989-04-25 | Alza Corporation | Dispenser with movable matrix comprising a plurality of tiny pills |
| DE69524214T3 (de) * | 1994-05-06 | 2008-05-15 | Pfizer Inc. | Azithromycin enthaltende arzneiverabreichungsformen mit gesteuerter wirkstoffabgabe |
| US5837284A (en) * | 1995-12-04 | 1998-11-17 | Mehta; Atul M. | Delivery of multiple doses of medications |
| PT957899E (pt) * | 1996-08-16 | 2003-07-31 | Alza Corp | Forma de dosagem para proporcionar um medicamento numa dose crescente |
| PT932388E (pt) * | 1996-09-30 | 2006-07-31 | Alza Corp | Forma de dosagem e metodo para administracao de farmacos |
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- 1999-05-27 CN CNB998069701A patent/CN1209098C/zh not_active Expired - Lifetime
- 1999-05-27 AU AU43197/99A patent/AU4319799A/en not_active Abandoned
- 1999-05-27 KR KR1020087021536A patent/KR20080083074A/ko not_active Ceased
- 1999-05-27 DK DK99955212T patent/DK1083879T3/da active
- 1999-05-27 IL IL14002099A patent/IL140020A0/xx unknown
- 1999-05-27 HK HK02108159.8A patent/HK1046638B/zh not_active IP Right Cessation
- 1999-05-27 JP JP2000551752A patent/JP2002516848A/ja not_active Withdrawn
- 1999-05-27 AT AT99955212T patent/ATE277594T1/de active
- 1999-05-27 WO PCT/US1999/011920 patent/WO1999062496A1/en not_active Ceased
- 1999-05-27 CA CA002333688A patent/CA2333688A1/en not_active Abandoned
- 1999-05-27 PT PT99955212T patent/PT1083879E/pt unknown
- 1999-05-27 EP EP04075594A patent/EP1449524A1/en not_active Withdrawn
- 1999-05-27 NZ NZ508567A patent/NZ508567A/xx not_active IP Right Cessation
- 1999-05-27 DE DE69920689T patent/DE69920689T2/de not_active Expired - Lifetime
- 1999-05-27 ES ES99955212T patent/ES2229783T3/es not_active Expired - Lifetime
- 1999-05-27 EP EP99955212A patent/EP1083879B1/en not_active Expired - Lifetime
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2000
- 2000-11-28 NO NO20006007A patent/NO330235B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20006007L (no) | 2001-02-05 |
| DE69920689D1 (de) | 2004-11-04 |
| KR20080083074A (ko) | 2008-09-12 |
| NO330235B1 (no) | 2011-03-07 |
| DK1083879T3 (da) | 2005-01-31 |
| IL140020A0 (en) | 2002-02-10 |
| WO1999062496A1 (en) | 1999-12-09 |
| EP1449524A1 (en) | 2004-08-25 |
| CN1352549A (zh) | 2002-06-05 |
| HK1035492A1 (en) | 2001-11-30 |
| PT1083879E (pt) | 2005-01-31 |
| CA2333688A1 (en) | 1999-12-09 |
| AU4319799A (en) | 1999-12-20 |
| NO20006007D0 (no) | 2000-11-28 |
| HK1046638A1 (en) | 2003-01-24 |
| DE69920689T2 (de) | 2005-02-24 |
| ATE277594T1 (de) | 2004-10-15 |
| HK1046638B (zh) | 2006-02-24 |
| CN1209098C (zh) | 2005-07-06 |
| EP1083879B1 (en) | 2004-09-29 |
| JP2002516848A (ja) | 2002-06-11 |
| NZ508567A (en) | 2004-02-27 |
| EP1083879A1 (en) | 2001-03-21 |
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