ES2226821T3 - Procedimiento de obtencion de polimeros solubles de glucosa ramificados. - Google Patents
Procedimiento de obtencion de polimeros solubles de glucosa ramificados.Info
- Publication number
- ES2226821T3 ES2226821T3 ES00922758T ES00922758T ES2226821T3 ES 2226821 T3 ES2226821 T3 ES 2226821T3 ES 00922758 T ES00922758 T ES 00922758T ES 00922758 T ES00922758 T ES 00922758T ES 2226821 T3 ES2226821 T3 ES 2226821T3
- Authority
- ES
- Spain
- Prior art keywords
- starch
- branching
- temperature
- minutes
- glucose polymers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims abstract description 66
- 239000008103 glucose Substances 0.000 title claims abstract description 66
- 229920000642 polymer Polymers 0.000 title claims abstract description 64
- 238000000034 method Methods 0.000 title claims description 49
- 229920002472 Starch Polymers 0.000 claims description 75
- 235000019698 starch Nutrition 0.000 claims description 75
- 239000008107 starch Substances 0.000 claims description 53
- 102000004190 Enzymes Human genes 0.000 claims description 26
- 108090000790 Enzymes Proteins 0.000 claims description 26
- 241000195493 Cryptophyta Species 0.000 claims description 14
- 229920000881 Modified starch Polymers 0.000 claims description 10
- 235000019426 modified starch Nutrition 0.000 claims description 10
- 102000003925 1,4-alpha-Glucan Branching Enzyme Human genes 0.000 claims description 7
- 108090000344 1,4-alpha-Glucan Branching Enzyme Proteins 0.000 claims description 7
- 229920002527 Glycogen Polymers 0.000 claims description 7
- 229940096919 glycogen Drugs 0.000 claims description 7
- 239000000725 suspension Substances 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 241000894006 Bacteria Species 0.000 claims description 4
- 241000588724 Escherichia coli Species 0.000 claims description 3
- 244000005700 microbiome Species 0.000 claims description 3
- 239000007900 aqueous suspension Substances 0.000 claims description 2
- 238000002955 isolation Methods 0.000 claims description 2
- 241000195597 Chlamydomonas reinhardtii Species 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 238000004184 polymer manufacturing process Methods 0.000 claims 1
- 238000009826 distribution Methods 0.000 abstract description 17
- 238000012360 testing method Methods 0.000 abstract description 16
- 235000000346 sugar Nutrition 0.000 abstract description 9
- 239000007864 aqueous solution Substances 0.000 abstract description 4
- 229940088598 enzyme Drugs 0.000 description 23
- 229920000945 Amylopectin Polymers 0.000 description 10
- 229920000856 Amylose Polymers 0.000 description 10
- 241000196324 Embryophyta Species 0.000 description 10
- 238000004458 analytical method Methods 0.000 description 10
- 238000002360 preparation method Methods 0.000 description 10
- 238000003860 storage Methods 0.000 description 9
- 238000011282 treatment Methods 0.000 description 9
- 108090000623 proteins and genes Proteins 0.000 description 8
- 235000013305 food Nutrition 0.000 description 7
- 238000005259 measurement Methods 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 229920002261 Corn starch Polymers 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 5
- 239000008120 corn starch Substances 0.000 description 5
- 229920001519 homopolymer Polymers 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 239000000499 gel Substances 0.000 description 4
- 239000008187 granular material Substances 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 150000008163 sugars Chemical class 0.000 description 4
- 108090000637 alpha-Amylases Proteins 0.000 description 3
- 102000004139 alpha-Amylases Human genes 0.000 description 3
- 229940024171 alpha-amylase Drugs 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 229930182470 glycoside Natural products 0.000 description 3
- 150000002338 glycosides Chemical class 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 241000195585 Chlamydomonas Species 0.000 description 2
- 229920001353 Dextrin Polymers 0.000 description 2
- 239000004375 Dextrin Substances 0.000 description 2
- 238000005481 NMR spectroscopy Methods 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 240000008042 Zea mays Species 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- 230000021736 acetylation Effects 0.000 description 2
- 238000006640 acetylation reaction Methods 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 238000012512 characterization method Methods 0.000 description 2
- 239000003638 chemical reducing agent Substances 0.000 description 2
- 238000004587 chromatography analysis Methods 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 238000010411 cooking Methods 0.000 description 2
- 235000019425 dextrin Nutrition 0.000 description 2
- 230000002255 enzymatic effect Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000012634 fragment Substances 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- -1 pululanase Proteins 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
- 241001474374 Blennius Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 230000004544 DNA amplification Effects 0.000 description 1
- 102100037709 Desmocollin-3 Human genes 0.000 description 1
- 239000004606 Fillers/Extenders Substances 0.000 description 1
- 101000880960 Homo sapiens Desmocollin-3 Proteins 0.000 description 1
- 108010028688 Isoamylase Proteins 0.000 description 1
- 229920002774 Maltodextrin Polymers 0.000 description 1
- 239000005913 Maltodextrin Substances 0.000 description 1
- 108010065084 Phosphorylase a Proteins 0.000 description 1
- 101000662549 Zea mays Sucrose synthase 1 Proteins 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 108010019077 beta-Amylase Proteins 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 238000001311 chemical methods and process Methods 0.000 description 1
- 238000013375 chromatographic separation Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 235000019621 digestibility Nutrition 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000007071 enzymatic hydrolysis Effects 0.000 description 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- 238000012869 ethanol precipitation Methods 0.000 description 1
- 238000006266 etherification reaction Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000005243 fluidization Methods 0.000 description 1
- 238000005227 gel permeation chromatography Methods 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000000425 proton nuclear magnetic resonance spectrum Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 150000008495 β-glucosides Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
- C08B30/18—Dextrin, e.g. yellow canari, white dextrin, amylodextrin or maltodextrin; Methods of depolymerisation, e.g. by irradiation or mechanically
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/16—Preparation of compounds containing saccharide radicals produced by the action of an alpha-1, 6-glucosidase, e.g. amylose, debranched amylopectin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Jellies, Jams, And Syrups (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9905523 | 1999-04-30 | ||
| FR9905523A FR2792941B1 (fr) | 1999-04-30 | 1999-04-30 | Polymeres solubles de glucose branches et leur procede d'obtention |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2226821T3 true ES2226821T3 (es) | 2005-04-01 |
Family
ID=9545092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES00922758T Expired - Lifetime ES2226821T3 (es) | 1999-04-30 | 2000-04-26 | Procedimiento de obtencion de polimeros solubles de glucosa ramificados. |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1177216B1 (enExample) |
| JP (1) | JP4823421B2 (enExample) |
| KR (1) | KR100803833B1 (enExample) |
| CN (1) | CN1197878C (enExample) |
| AT (1) | ATE274525T1 (enExample) |
| AU (1) | AU777378B2 (enExample) |
| CA (1) | CA2371185C (enExample) |
| DE (1) | DE60013271T2 (enExample) |
| DK (1) | DK1177216T3 (enExample) |
| ES (1) | ES2226821T3 (enExample) |
| FR (1) | FR2792941B1 (enExample) |
| MX (1) | MXPA01011078A (enExample) |
| NO (1) | NO330330B1 (enExample) |
| PT (1) | PT1177216E (enExample) |
| WO (1) | WO2000066633A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2832728B1 (fr) * | 2001-11-29 | 2004-01-30 | Roquette Freres | Procede continu de modification de l'amidon et de ses derives par enzymes de branchement |
| DE10209821A1 (de) | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung von Proteinen an ein modifiziertes Polysaccharid |
| FR2840612B1 (fr) * | 2002-06-06 | 2005-05-06 | Roquette Freres | Polymeres solubles de glucose hautement branches et leur procede d'obtention |
| WO2003106502A1 (en) * | 2002-06-17 | 2003-12-24 | Novozymes A/S | Methods for producing dextrins using enzymes |
| DE10237442B4 (de) | 2002-08-16 | 2004-08-19 | Fresenius Kabi Deutschland Gmbh | Hochverzweigte, niedrig substituierte Stärkeprodukte |
| WO2005014655A2 (en) | 2003-08-08 | 2005-02-17 | Fresenius Kabi Deutschland Gmbh | Conjugates of hydroxyalkyl starch and a protein |
| FR2864088B1 (fr) * | 2003-12-19 | 2006-04-28 | Roquette Freres | Polymeres solubles de glucose hautement branches |
| JP4893980B2 (ja) | 2005-04-08 | 2012-03-07 | 株式会社林原生物化学研究所 | 分岐澱粉とその製造方法並びに用途 |
| WO2008044588A1 (fr) * | 2006-10-06 | 2008-04-17 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Dérivé d'amidon ramifié, procédé d'obtention et article moulé contenant le dérivé d'amidon ramifié |
| JPWO2008044586A1 (ja) * | 2006-10-06 | 2010-02-12 | 株式会社林原生物化学研究所 | 分岐澱粉を含有する成形物 |
| EP1943908A1 (en) * | 2006-12-29 | 2008-07-16 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Novel slowly digestible storage carbohydrate |
| JP2009124994A (ja) * | 2007-11-22 | 2009-06-11 | Akita Prefectural Univ | 分岐糖類の製造方法および飲食品 |
| EP2070951A1 (en) | 2007-12-14 | 2009-06-17 | Fresenius Kabi Deutschland GmbH | Method for producing a hydroxyalkyl starch derivatives with two linkers |
| EP2070950A1 (en) | 2007-12-14 | 2009-06-17 | Fresenius Kabi Deutschland GmbH | Hydroxyalkyl starch derivatives and process for their preparation |
| EP2172489A1 (en) * | 2008-09-15 | 2010-04-07 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO | Method for altering starch using a microbial branching enzyme |
| PH12012500689A1 (en) | 2009-10-26 | 2012-10-29 | Nestec Sa | Stable thickener formulations |
| FR2955861B1 (fr) * | 2010-02-02 | 2013-03-22 | Roquette Freres | Polymeres solubles de glucose branches pour la dialyse peritoneale |
| US20140073602A9 (en) | 2010-07-09 | 2014-03-13 | Fresenius Kabi Deutschland Gmbh | Nitric oxide delivering hydroxyalkyl starch derivatives |
| CN104411885B (zh) * | 2012-06-29 | 2017-04-12 | 艾维贝合作公司 | 通过膜涂布来涂布纸张的方法和设备 |
| FR2998290B1 (fr) | 2012-11-16 | 2014-12-19 | Roquette Freres | Procede de potabilisation |
| CN103404764B (zh) * | 2013-08-23 | 2015-06-17 | 内蒙古伊利实业集团股份有限公司 | 一种抗性麦芽糊精及其制备方法 |
| FR3016877A1 (fr) | 2014-01-29 | 2015-07-31 | Roquette Freres | Procede de traitement de l'eau |
| CN104544473A (zh) * | 2014-12-08 | 2015-04-29 | 江南大学 | 一种抑制淀粉回生的生物改性方法 |
| JP6470099B2 (ja) * | 2015-04-24 | 2019-02-13 | 昭和産業株式会社 | 澱粉分解物、並びに該澱粉分解物を用いた粉飴、シラップ及び飲食品 |
| ES2993033T3 (en) * | 2016-07-08 | 2024-12-20 | Roquette Freres | Hydrogenated glucose polymer composition containing dietary fibres |
| SE543895C2 (en) | 2019-12-18 | 2021-09-14 | Sveriges Staerkelseproducenter Foerening U P A | Converted starch and food comprising said converted starch |
| CN115895050B (zh) * | 2022-11-17 | 2025-03-11 | 江南大学 | 一种定向调控淀粉基可食用膜性能的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4454161A (en) * | 1981-02-07 | 1984-06-12 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Process for the production of branching enzyme, and a method for improving the qualities of food products therewith |
| JPS6075295A (ja) * | 1983-09-29 | 1985-04-27 | Takeda Chem Ind Ltd | 水溶性澱粉質の製造法およびこれを含有せしめる飲食物の製造法 |
| JP3107358B2 (ja) * | 1994-09-13 | 2000-11-06 | 江崎グリコ株式会社 | 環状構造を有するグルカンおよびその製造方法 |
-
1999
- 1999-04-30 FR FR9905523A patent/FR2792941B1/fr not_active Expired - Fee Related
-
2000
- 2000-04-26 AU AU43052/00A patent/AU777378B2/en not_active Ceased
- 2000-04-26 DE DE60013271T patent/DE60013271T2/de not_active Expired - Lifetime
- 2000-04-26 JP JP2000615661A patent/JP4823421B2/ja not_active Expired - Fee Related
- 2000-04-26 CA CA2371185A patent/CA2371185C/fr not_active Expired - Fee Related
- 2000-04-26 AT AT00922758T patent/ATE274525T1/de active
- 2000-04-26 PT PT00922758T patent/PT1177216E/pt unknown
- 2000-04-26 KR KR1020017013894A patent/KR100803833B1/ko not_active Expired - Fee Related
- 2000-04-26 WO PCT/FR2000/001109 patent/WO2000066633A1/fr not_active Ceased
- 2000-04-26 DK DK00922758T patent/DK1177216T3/da active
- 2000-04-26 ES ES00922758T patent/ES2226821T3/es not_active Expired - Lifetime
- 2000-04-26 EP EP00922758A patent/EP1177216B1/fr not_active Expired - Lifetime
- 2000-04-26 MX MXPA01011078A patent/MXPA01011078A/es active IP Right Grant
- 2000-04-26 CN CNB008069387A patent/CN1197878C/zh not_active Expired - Fee Related
-
2001
- 2001-10-25 NO NO20015224A patent/NO330330B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2792941A1 (fr) | 2000-11-03 |
| ATE274525T1 (de) | 2004-09-15 |
| NO330330B1 (no) | 2011-03-28 |
| PT1177216E (pt) | 2005-01-31 |
| DE60013271T2 (de) | 2005-09-15 |
| MXPA01011078A (es) | 2002-07-22 |
| CN1197878C (zh) | 2005-04-20 |
| CN1349544A (zh) | 2002-05-15 |
| NO20015224L (no) | 2001-10-25 |
| EP1177216B1 (fr) | 2004-08-25 |
| JP2002543248A (ja) | 2002-12-17 |
| CA2371185C (fr) | 2010-09-14 |
| DE60013271D1 (de) | 2004-09-30 |
| DK1177216T3 (da) | 2005-01-17 |
| FR2792941B1 (fr) | 2001-07-27 |
| AU777378B2 (en) | 2004-10-14 |
| JP4823421B2 (ja) | 2011-11-24 |
| EP1177216A1 (fr) | 2002-02-06 |
| CA2371185A1 (fr) | 2000-11-09 |
| AU4305200A (en) | 2000-11-17 |
| KR20020010622A (ko) | 2002-02-04 |
| KR100803833B1 (ko) | 2008-02-14 |
| NO20015224D0 (no) | 2001-10-25 |
| WO2000066633A1 (fr) | 2000-11-09 |
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