ES2195005T3 - Modificacion quimica post-sintesis de reactivos particulados. - Google Patents

Modificacion quimica post-sintesis de reactivos particulados.

Info

Publication number
ES2195005T3
ES2195005T3 ES96927297T ES96927297T ES2195005T3 ES 2195005 T3 ES2195005 T3 ES 2195005T3 ES 96927297 T ES96927297 T ES 96927297T ES 96927297 T ES96927297 T ES 96927297T ES 2195005 T3 ES2195005 T3 ES 2195005T3
Authority
ES
Spain
Prior art keywords
reagents
particulated
synthesis
chemical modification
modification post
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96927297T
Other languages
English (en)
Inventor
Victor Pichai Chu
Alan Robert Craig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dade Behring Inc
Original Assignee
Dade Behring Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Inc filed Critical Dade Behring Inc
Application granted granted Critical
Publication of ES2195005T3 publication Critical patent/ES2195005T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

SE PROPORCIONA UN METODO PARA AUMENTAR LA ESTABILIDAD Y AUMENTAR LA ACTIVIDAD DE REACTIVOS DE PARTICULAS POLIMERICAS POR MEDIO DE LA INCUBACION DE UNA PARTICULA POLIMERICA QUE SE HA UNIDO DE MANERA COVALENTE CON UN COMPUESTO DE INTERES BIOLOGICO, COMO, POR EJEMPLO, UN MEDICAMENTO, CON UN AGENTE DE MODIFICACION QUE APLICARA UNA CARGA NEGATIVA SOBRE LA SUPERFICIE DE LA PARTICULA POLIMERICA Y REDUCIRA LOS GRUPOS FUNCIONALES RESIDUALES. PREFERIBLEMENTE, EL AGENTE DE MODIFICACION ES UN NUCLEOFILO ANIONICO SELECCIONADO DE ENTRE EL GRUPO CONSISTENTE EN ACIDO MERCAPTOACETICO-{BE} Y TIOSULFATOS.
ES96927297T 1995-08-03 1996-08-02 Modificacion quimica post-sintesis de reactivos particulados. Expired - Lifetime ES2195005T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/510,687 US5854083A (en) 1995-08-03 1995-08-03 Post synthesis chemical modification of particle reagents

Publications (1)

Publication Number Publication Date
ES2195005T3 true ES2195005T3 (es) 2003-12-01

Family

ID=24031753

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96927297T Expired - Lifetime ES2195005T3 (es) 1995-08-03 1996-08-02 Modificacion quimica post-sintesis de reactivos particulados.

Country Status (8)

Country Link
US (1) US5854083A (es)
EP (1) EP0784795B1 (es)
JP (1) JP3663516B2 (es)
CN (1) CN1166205A (es)
AT (1) ATE236404T1 (es)
DE (1) DE69627121T2 (es)
ES (1) ES2195005T3 (es)
WO (1) WO1997006438A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7212332B2 (en) * 2004-06-01 2007-05-01 Intel Corporation Micro-electromechanical system (MEMS) polyelectrolyte gel network pump
US7465765B2 (en) 2004-09-27 2008-12-16 Hewlett-Packard Development Company, L.P. Latex particulates with epoxide functional groups
JP6634202B2 (ja) * 2014-08-22 2020-01-22 Jsr株式会社 担体、担体の製造方法、及び標的物の精製方法
JP6224217B1 (ja) * 2016-12-27 2017-11-01 Jsr株式会社 ラテックス粒子分散液の保管方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5653465A (en) * 1979-10-05 1981-05-13 Toyo Jozo Co Ltd Improved method in measurement of enzyme immunity
EP0054685B1 (de) * 1980-12-23 1986-07-09 Roche Diagnostics GmbH Hydrophile Latexpartikel, Verfahren zu deren Herstellung und deren Verwendung
JPS5847258A (ja) * 1981-09-01 1983-03-18 イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− 光散乱イムノアツセイ用粒子試薬
US4401765A (en) * 1981-09-01 1983-08-30 E. I. Du Pont De Nemours And Company Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays
US4480042A (en) * 1981-10-28 1984-10-30 E. I. Du Pont De Nemours And Company Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays
JPH0762683B2 (ja) * 1988-04-01 1995-07-05 明治製菓株式会社 安定なラテックス試薬
CA1341592C (en) * 1989-07-07 2009-04-14 Abbott Laboratories Ion capture reagents and methods for performing binding assays

Also Published As

Publication number Publication date
US5854083A (en) 1998-12-29
JPH10509805A (ja) 1998-09-22
DE69627121D1 (de) 2003-05-08
WO1997006438A1 (en) 1997-02-20
CN1166205A (zh) 1997-11-26
JP3663516B2 (ja) 2005-06-22
EP0784795B1 (en) 2003-04-02
DE69627121T2 (de) 2004-03-04
ATE236404T1 (de) 2003-04-15
EP0784795A1 (en) 1997-07-23

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