ES2185857T3 - Procedimiento de preparacion de derivados de halogenoacetamida. - Google Patents

Procedimiento de preparacion de derivados de halogenoacetamida.

Info

Publication number
ES2185857T3
ES2185857T3 ES97120490T ES97120490T ES2185857T3 ES 2185857 T3 ES2185857 T3 ES 2185857T3 ES 97120490 T ES97120490 T ES 97120490T ES 97120490 T ES97120490 T ES 97120490T ES 2185857 T3 ES2185857 T3 ES 2185857T3
Authority
ES
Spain
Prior art keywords
halogenoacetamide
derivatives
procedure
preparation
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97120490T
Other languages
English (en)
Inventor
Shinji Kamihara
Tohru Kaneuchi
Keiji Uchiyama
Tatsuya Terada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2185857T3 publication Critical patent/ES2185857T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/38—2-Pyrrolones
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B41/00—After-treatment of mortars, concrete, artificial stone or ceramics; Treatment of natural stone
    • C04B41/45—Coating or impregnating, e.g. injection in masonry, partial coating of green or fired ceramics, organic coating compositions for adhering together two concrete elements
    • C04B41/46—Coating or impregnating, e.g. injection in masonry, partial coating of green or fired ceramics, organic coating compositions for adhering together two concrete elements with organic materials
    • C04B41/48—Macromolecular compounds
    • C04B41/4857—Other macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C04B41/4869—Polyvinylalcohols, polyvinylacetates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Ceramic Engineering (AREA)
  • Structural Engineering (AREA)
  • Materials Engineering (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE PRESENTA UN PROCESO PARA PREPARAR UN DERIVADO DE 2 - (1 PIRROLIDINIL)ACETAMIDA UTIL COMO AGENTE MEJORADOR DE LA FUNCION CEREBRAL, QUE CONSISTE EN LA REACCION DE UN DERIVADO HALOGENADO DE ACETAMIDA CON UNA 2 - PIRROLIDINA SUSTITUIDA O NO SUSTITUIDA, PREPARANDO EL DERIVADO HALOGENADO DE ACETAMIDA MEDIANTE LA REACCION DE UNA AMINA Y UN CLORURO ACETILADO DE HALOGENO. SE CONSIGUE UNA PRODUCCION ABUNDANTE DEL COMPUESTO INTERMEDIARIO ASI COMO DEL PRODUCTO FINAL A BAJO COSTE.
ES97120490T 1992-06-19 1993-06-18 Procedimiento de preparacion de derivados de halogenoacetamida. Expired - Lifetime ES2185857T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16049692 1992-06-19

Publications (1)

Publication Number Publication Date
ES2185857T3 true ES2185857T3 (es) 2003-05-01

Family

ID=15716197

Family Applications (2)

Application Number Title Priority Date Filing Date
ES93109812T Expired - Lifetime ES2176192T3 (es) 1992-06-19 1993-06-18 Procedimiento para la preparacion de derivados 2-oxopirrolidinilacetamida.
ES97120490T Expired - Lifetime ES2185857T3 (es) 1992-06-19 1993-06-18 Procedimiento de preparacion de derivados de halogenoacetamida.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES93109812T Expired - Lifetime ES2176192T3 (es) 1992-06-19 1993-06-18 Procedimiento para la preparacion de derivados 2-oxopirrolidinilacetamida.

Country Status (14)

Country Link
EP (2) EP0574952B1 (es)
JP (1) JPH0665197A (es)
KR (1) KR100223387B1 (es)
CN (2) CN1085893A (es)
AT (2) ATE215931T1 (es)
CA (1) CA2098663A1 (es)
DE (2) DE69332441T2 (es)
DK (2) DK0574952T3 (es)
ES (2) ES2176192T3 (es)
FI (1) FI102748B1 (es)
HK (1) HK1009131A1 (es)
NO (1) NO179903C (es)
PT (2) PT839800E (es)
TW (1) TW218009B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0819676T3 (da) 1995-03-23 2003-01-27 Daiichi Seiyaku Co Vandfri krystaller
US6107330A (en) * 1995-08-07 2000-08-22 Daiichi Pharmaceutical Co., Ltd. Inhibitor for narcotic analgesic dependence/resistance acquisition
DE60138733D1 (de) 2000-12-28 2009-06-25 Hamilton Pharmaceuticals Inc Arzneimittel zur behandlung und vermeidung neurogener schmerzen
CN100593538C (zh) * 2007-05-23 2010-03-10 浙江工业大学 一种n-取代丙烯酰基-2,5-吡咯二酮类化合物的制备方法
KR101006734B1 (ko) * 2008-10-14 2011-01-10 차준돈 접 붙이기 수단을 이용한 관상용 영지버섯 제조방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2863752A (en) * 1953-10-30 1958-12-09 Monsanto Chemicals Herbicides
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
US3647876A (en) * 1969-08-14 1972-03-07 Virginia Chemicals Inc Process in the preparation of n n-di-n-propyl-alpha-chloroacetamid
CH518266A (fr) * 1971-05-21 1972-01-31 Ct D Etudes Pour L Ind Pharma Procédé de préparation d'un nouveau dérivé de la xylidine
FR2216267A1 (en) * 1973-02-01 1974-08-30 Nitrokemia Ipartelepek N-isopropyl chloroacetanilide prodn - by chloroacetylation of N-isopropylaniline
CH582651A5 (es) * 1973-05-30 1976-12-15 Eszakmagyar Vegyimuevek
DE2835157A1 (de) * 1978-08-10 1980-02-21 Bayer Ag Verfahren zur herstellung von n-substituierten alpha -halogenacetaniliden
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
DE3120361A1 (de) * 1981-05-22 1982-12-16 Chemische Werke Hüls AG, 4370 Marl Verfahren zur herstellung von n-benzyl-n-isopropylpivaloylamid

Also Published As

Publication number Publication date
NO179903C (no) 1997-01-08
KR940005570A (ko) 1994-03-21
NO932231D0 (no) 1993-06-17
CN1085893A (zh) 1994-04-27
NO179903B (no) 1996-09-30
HK1009131A1 (en) 1999-05-28
PT839800E (pt) 2003-02-28
DK0839800T3 (da) 2003-02-24
FI932813A0 (fi) 1993-06-17
EP0839800A1 (en) 1998-05-06
PT574952E (pt) 2002-08-30
TW218009B (es) 1993-12-21
EP0839800B1 (en) 2002-10-23
CN1143077A (zh) 1997-02-19
EP0574952B1 (en) 2002-04-10
DE69331792D1 (de) 2002-05-16
DE69332441D1 (de) 2002-11-28
KR100223387B1 (en) 1999-10-15
NO932231L (no) 1993-12-20
DK0574952T3 (da) 2002-06-10
ATE226570T1 (de) 2002-11-15
ATE215931T1 (de) 2002-04-15
JPH0665197A (ja) 1994-03-08
ES2176192T3 (es) 2002-12-01
FI102748B (fi) 1999-02-15
DE69332441T2 (de) 2003-08-14
EP0574952A1 (en) 1993-12-22
DE69331792T2 (de) 2004-11-04
FI932813A (fi) 1993-12-20
CA2098663A1 (en) 1993-12-20
FI102748B1 (fi) 1999-02-15

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