ES2180652T3 - Sintesis de guanidinas penta-sustituidas. - Google Patents
Sintesis de guanidinas penta-sustituidas.Info
- Publication number
- ES2180652T3 ES2180652T3 ES95930256T ES95930256T ES2180652T3 ES 2180652 T3 ES2180652 T3 ES 2180652T3 ES 95930256 T ES95930256 T ES 95930256T ES 95930256 T ES95930256 T ES 95930256T ES 2180652 T3 ES2180652 T3 ES 2180652T3
- Authority
- ES
- Spain
- Prior art keywords
- substituted
- penta
- guanidines
- synthesis
- replaced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 150000002357 guanidines Chemical class 0.000 title 1
- 150000001412 amines Chemical class 0.000 abstract 3
- -1 penta-substituted guanidines Chemical class 0.000 abstract 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LA PRESENTE INVENCION ES LA NUEVA SINTESIS DE GUANIDINAS PENTASUSTITUIDAS ESTERICAMENTE OBSTRUIDAS MEDIANTE UN PROCEDIMIENTO EN EL QUE (1A) UN ISOCIANATO SE HACE REACCIONAR PRIMERO CON UNA AMINA DI-SUSTITUIDA O (1B) UNA UREA SE HACE REACCIONAR CON DOS MOLES DE UNA AMINA MONO-SUSTITUIDA PARA FORMAR UNA UREA TRISUSTITUIDA SEGUIDA DE (2) TRATAMIENTO DE LA UREA TRI-SUSTITUIDA CON UN AGENTE ACTIVADOR ANTES DE HACERLO REACCIONAR CON UNA SEGUNDA AMINA DI-SUSTITUIDA EN PRESENCIA DE UNA BASE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/304,322 US5696290A (en) | 1994-09-12 | 1994-09-12 | Synthesis of penta-substituted guanidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2180652T3 true ES2180652T3 (es) | 2003-02-16 |
Family
ID=23176030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95930256T Expired - Lifetime ES2180652T3 (es) | 1994-09-12 | 1995-08-23 | Sintesis de guanidinas penta-sustituidas. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5696290A (es) |
| EP (1) | EP0781272B1 (es) |
| JP (1) | JPH10504827A (es) |
| CN (1) | CN1164854A (es) |
| AT (1) | ATE221873T1 (es) |
| AU (1) | AU4651196A (es) |
| DE (1) | DE69527719T2 (es) |
| DK (1) | DK0781272T3 (es) |
| ES (1) | ES2180652T3 (es) |
| PT (1) | PT781272E (es) |
| WO (1) | WO1996008469A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR029361A1 (es) * | 1999-05-28 | 2003-06-25 | Smithkline Beecham Corp | Compuestos de guanidina ciclicas antagonistas de los receptores de la il- 8, composicion farmaceutica que los comprende y el uso de los mismos para la manufactura de un medicamento |
| US20050029194A1 (en) * | 2003-08-07 | 2005-02-10 | Hall David Bruce | Method for removal of guanidine compound from aqueous media |
| FR2925496A1 (fr) * | 2007-12-20 | 2009-06-26 | Bluestar Silicones France Soc | Composes a structure guanidine et leurs utilisations comme catalyseurs de polycondensation d'organopolysiloxanes. |
| CA2744667C (fr) * | 2008-11-25 | 2014-07-08 | Bluestar Silicones France | Composes a structure guanidine et leurs utilisations comme catalyseurs de polycondensation d'organopolysiloxanes |
| CN120795289B (zh) * | 2025-09-08 | 2025-11-21 | 合肥工业大学 | 一种胍基金属配合物绿色催化剂及其制备方法、应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US533652A (en) * | 1895-02-05 | Fish-hook | ||
| DE1064051B (de) * | 1958-04-09 | 1959-08-27 | Basf Ag | Verfahren zur Herstellung von substituierten Harnstoffen |
| DE1170931B (de) * | 1962-09-14 | 1964-05-27 | Bayer Ag | Verfahren zur Herstellung von substituierten Guanidinen |
| US4358613A (en) * | 1979-12-26 | 1982-11-09 | General Electric Company | Process for the preparation of substituted guanidines |
| FR2509724B1 (fr) * | 1981-07-15 | 1985-10-25 | Centre Nat Rech Scient | Nouvelles guanidines a fort encombrement sterique et procedes pour leur preparation |
| CN1063279A (zh) * | 1992-03-05 | 1992-08-05 | 山东师范大学 | 合成除草剂异丙隆的方法 |
| US5189205A (en) * | 1992-03-16 | 1993-02-23 | Monsanto Compamy | Process for preparing isocyanates |
-
1994
- 1994-09-12 US US08/304,322 patent/US5696290A/en not_active Expired - Lifetime
-
1995
- 1995-08-23 JP JP8508285A patent/JPH10504827A/ja not_active Ceased
- 1995-08-23 ES ES95930256T patent/ES2180652T3/es not_active Expired - Lifetime
- 1995-08-23 AU AU46511/96A patent/AU4651196A/en not_active Abandoned
- 1995-08-23 AT AT95930256T patent/ATE221873T1/de active
- 1995-08-23 DK DK95930256T patent/DK0781272T3/da active
- 1995-08-23 PT PT95930256T patent/PT781272E/pt unknown
- 1995-08-23 EP EP95930256A patent/EP0781272B1/en not_active Expired - Lifetime
- 1995-08-23 CN CN95196061A patent/CN1164854A/zh active Pending
- 1995-08-23 DE DE69527719T patent/DE69527719T2/de not_active Expired - Lifetime
- 1995-08-23 WO PCT/US1995/010712 patent/WO1996008469A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US5696290A (en) | 1997-12-09 |
| ATE221873T1 (de) | 2002-08-15 |
| PT781272E (pt) | 2002-12-31 |
| DE69527719D1 (de) | 2002-09-12 |
| EP0781272A1 (en) | 1997-07-02 |
| WO1996008469A1 (en) | 1996-03-21 |
| JPH10504827A (ja) | 1998-05-12 |
| AU4651196A (en) | 1996-03-29 |
| DE69527719T2 (de) | 2003-04-03 |
| EP0781272B1 (en) | 2002-08-07 |
| DK0781272T3 (da) | 2002-12-02 |
| CN1164854A (zh) | 1997-11-12 |
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