ES2176185T3 - Procedimiento para la obtencion de derivados del acido fluorquinoleina carboxilico-3. - Google Patents

Procedimiento para la obtencion de derivados del acido fluorquinoleina carboxilico-3.

Info

Publication number
ES2176185T3
ES2176185T3 ES92402742T ES92402742T ES2176185T3 ES 2176185 T3 ES2176185 T3 ES 2176185T3 ES 92402742 T ES92402742 T ES 92402742T ES 92402742 T ES92402742 T ES 92402742T ES 2176185 T3 ES2176185 T3 ES 2176185T3
Authority
ES
Spain
Prior art keywords
fluorquinolein
carboxilic
procedure
acid
obtaining derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92402742T
Other languages
English (en)
Inventor
Christophe Daubie
Jean-Jacques Legrand
Clive Pemberton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of ES2176185T3 publication Critical patent/ES2176185T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/44—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedimiento para la preparación de un derivado de la quinoleina, de fórmula general: **fórmula** en la que R es un átomo de hidrógeno o un radical alquilo, caracterizado porque se efectúan las etapas siguientes: acción de un derivado del ácido malónico de fórmula general: R1OCO-CH2-COOR1 en la que los radicales R1 son radicales alquilo tales como los que se han definido anteriormente para R, sobre un derivado del nitrobenzaldehido de fórmula: **fórmula** ciclación del medio ácido del derivado nitrado de fórmula general en la que R1 se define, anteriormente, seguido, eventualmente, de la liberación de una función ácida, si se quiere obtener un derivado de la quinoleina en el cual R es un átomo de hidrógeno.
ES92402742T 1991-10-10 1992-10-08 Procedimiento para la obtencion de derivados del acido fluorquinoleina carboxilico-3. Expired - Lifetime ES2176185T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9112480A FR2682378B1 (fr) 1991-10-10 1991-10-10 Nouveaux derives de l'acide fluoroquinoleine carboxylique-3 et leur preparation.

Publications (1)

Publication Number Publication Date
ES2176185T3 true ES2176185T3 (es) 2002-12-01

Family

ID=9417775

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92402742T Expired - Lifetime ES2176185T3 (es) 1991-10-10 1992-10-08 Procedimiento para la obtencion de derivados del acido fluorquinoleina carboxilico-3.

Country Status (25)

Country Link
US (1) US5442070A (es)
EP (2) EP0607329A1 (es)
JP (1) JP3252852B2 (es)
KR (1) KR100249637B1 (es)
AT (1) ATE212982T1 (es)
AU (1) AU672370B2 (es)
CA (1) CA2119757C (es)
CZ (1) CZ284595B6 (es)
DE (1) DE69232406T2 (es)
DK (1) DK0538100T3 (es)
ES (1) ES2176185T3 (es)
FI (1) FI105400B (es)
FR (1) FR2682378B1 (es)
HU (1) HU214955B (es)
IL (1) IL103403A (es)
MX (1) MX9205773A (es)
NO (1) NO301640B1 (es)
NZ (1) NZ244646A (es)
PT (1) PT538100E (es)
RU (1) RU2109014C1 (es)
SK (1) SK280886B6 (es)
TW (1) TW224093B (es)
WO (1) WO1993007127A1 (es)
YU (1) YU48443B (es)
ZA (1) ZA927744B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2703681B1 (fr) * 1993-04-08 1995-05-12 Bellon Labor Sa Roger Procede de preparation de fluoro-6-halogeno-2 quinoleine
WO2005026166A1 (fr) * 2003-09-16 2005-03-24 'chemical Diversity Research Institute', Ltd. Composition physiologiquement active, composition pharmaceutique, 1,2-dihydro[2,7]naphtyridine, procedes de fabrication et application
MD2909C2 (ro) * 2005-01-14 2006-06-30 Николае ТАРАН Procedeu de fabricare a vinurilor naturale cu zahăr rezidual

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1458205A (en) * 1973-04-13 1976-12-08 Pfizer Fused pyrimidin-4- 3h-ones as antiallergy agents
FR2593961B1 (fr) * 1986-02-04 1988-04-15 Orega Electro Mecanique Transformateur haute tension en technologie fractionnee, en particulier pour tube cathodique trichrome
DK111387A (da) * 1986-03-05 1987-09-06 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne
US4894084A (en) * 1987-12-29 1990-01-16 Fmc Corporation Substituted quinolinonyl and dihydroquinolinonyl triazolinone herbicides
US4909829A (en) * 1987-12-29 1990-03-20 Fmc Corporation Substituted quinolinonyl and dihydroquinolinonyl tetrazolinone herbicides
AU623474B2 (en) * 1989-01-16 1992-05-14 Laboratoire Roger Bellon New benzo(1,8)naphthyridine derivatives, their preparation and compositions containing them
NZ232092A (en) * 1989-01-16 1992-05-26 Bellon Labor Sa Roger 8-halo-7-fluoro-4-oxo-1,4-dihydro-benzo(b)(1,8) naphthyridine-3-carboxylic acid esters and preparation thereof
NZ232090A (en) * 1989-01-16 1990-12-21 Bellon Labor Sa Roger Halogen-containing 1-substituted-4-oxo-1,4-dihydro-benzo(b)(1,8)naphthyridine-3-carboxylic acid derivatives, preparation and pharmaceutical compositions thereof
US5385913A (en) * 1989-10-06 1995-01-31 Pfizer Inc. 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents

Also Published As

Publication number Publication date
PT538100E (pt) 2002-07-31
IL103403A (en) 1996-10-16
JP3252852B2 (ja) 2002-02-04
NO941244D0 (no) 1994-04-06
HU9401004D0 (en) 1994-08-29
FI941650A (fi) 1994-04-08
MX9205773A (es) 1993-04-01
FR2682378B1 (fr) 1995-04-07
EP0538100B1 (fr) 2002-02-06
TW224093B (es) 1994-05-21
NZ244646A (en) 1994-04-27
AU2874492A (en) 1993-05-03
CZ83394A3 (en) 1995-02-15
RU2109014C1 (ru) 1998-04-20
FI105400B (fi) 2000-08-15
AU672370B2 (en) 1996-10-03
CZ284595B6 (cs) 1999-01-13
IL103403A0 (en) 1993-03-15
US5442070A (en) 1995-08-15
SK280886B6 (sk) 2000-09-12
CA2119757A1 (fr) 1993-04-15
CA2119757C (fr) 2005-09-20
ATE212982T1 (de) 2002-02-15
NO941244L (no) 1994-05-24
KR940702846A (ko) 1994-09-17
WO1993007127A1 (fr) 1993-04-15
EP0607329A1 (fr) 1994-07-27
EP0538100A1 (fr) 1993-04-21
JPH07500101A (ja) 1995-01-05
ZA927744B (en) 1993-04-19
HU214955B (hu) 1998-08-28
HUT67486A (en) 1995-04-28
YU91192A (sh) 1995-03-27
DK0538100T3 (da) 2002-04-29
FR2682378A1 (fr) 1993-04-16
DE69232406T2 (de) 2002-08-22
DE69232406D1 (de) 2002-03-21
SK40394A3 (en) 1995-02-08
KR100249637B1 (ko) 2000-04-01
NO301640B1 (no) 1997-11-24
FI941650A0 (fi) 1994-04-08
YU48443B (sh) 1998-07-10

Similar Documents

Publication Publication Date Title
ES532149A0 (es) Procedimiento para la preparacion de nuevos compuestos fluoroalcoxilicos
NO880995L (no) Nye 5-alkoxy-2,4-diaminoalkylbenzener saavel som haarfarvemiddel med 5-alkoxy-2,4-diamino-alkylbenzen.
ES517699A0 (es) Procedimiento de preparacion de nuevas pirimido-quinoxalinas.
FI862909A0 (fi) Foerfarande foer framstaellning av nya indolkarboxamidderivat och deras salter.
ES2176185T3 (es) Procedimiento para la obtencion de derivados del acido fluorquinoleina carboxilico-3.
ES515872A0 (es) "procedimiento para la preparacion de nuevos derivados de acidos 4-fenoxialcarboxilicos sustituidos con radicales haterociclicos".
ES515106A0 (es) "procedimiento para la preparacion de compuestos de 1-fenilindazol-3-ona".
ES2039364T3 (es) Derivados de n - ariltetrahidroftalimida y sus productos previos.
ES555030A0 (es) Procedimiento para la obtencion de nuevos derivados de isoxazol
ES501601A0 (es) Procedimiento para la preparacion de nuevos 1-ariloxi-3-al- cohilamino-2-propanoles
ATE129499T1 (de) 2-aminonaphthyridin-derivat, seine herstellung und verwendung.
ES517039A0 (es) Procedimiento para la preparacion de un derivado de acido imidazolcarboxilico.
ES520136A0 (es) Un procedimiento para la preparacion de un derivado del acido furiloxazolila-cetico
ES536139A0 (es) Procedimiento para la preparacion de quinolinonas-4
ES536140A0 (es) Procedimiento para la preparacion de quinolinonas-4
FI953246A (fi) Välituotteet kinoliini-3-karboksyylihappojohdannaisten valmistamiseksi
ES2167971T3 (es) Procedimiento para la preparacion de dinitrilo de acido malonico.