ES2175753T3 - Injerto biosintetico y metodo para su produccion. - Google Patents
Injerto biosintetico y metodo para su produccion.Info
- Publication number
- ES2175753T3 ES2175753T3 ES98941248T ES98941248T ES2175753T3 ES 2175753 T3 ES2175753 T3 ES 2175753T3 ES 98941248 T ES98941248 T ES 98941248T ES 98941248 T ES98941248 T ES 98941248T ES 2175753 T3 ES2175753 T3 ES 2175753T3
- Authority
- ES
- Spain
- Prior art keywords
- transplant
- autologously
- production
- tissue
- biosynthetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3808—Endothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3826—Muscle cells, e.g. smooth muscle cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Botany (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Prostheses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La invención se refiere a un trasplante biosintético específico del receptor, constituido por tejido conjuntivo intresticial que comprende diversas células diferenciadas, colonizadas de manera casi autóloga, modificadas de manera autóloga o por ingeniería genética. Para producir tal trasplante, se trata un tejido o un material alógeno o xenógeno por vía enzimática o química para permitir la obtención de una matriz de colágeno prácticamente sin célula, no desnaturalizada, que se puede recolonizar por completo directamente con las células deseadas. El trasplante así obtenido puede utilizarse inmediatamente.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19727497 | 1997-06-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2175753T3 true ES2175753T3 (es) | 2002-11-16 |
Family
ID=7833911
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98941248T Expired - Lifetime ES2175753T3 (es) | 1997-06-27 | 1998-06-29 | Injerto biosintetico y metodo para su produccion. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0989867B1 (es) |
JP (1) | JP2002507907A (es) |
DE (2) | DE19828726A1 (es) |
ES (1) | ES2175753T3 (es) |
WO (1) | WO1999000152A2 (es) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999022781A2 (en) | 1997-10-31 | 1999-05-14 | Children's Medical Center Corporation | Bladder reconstruction |
US20030007954A1 (en) | 1999-04-12 | 2003-01-09 | Gail K. Naughton | Methods for using a three-dimensional stromal tissue to promote angiogenesis |
EP1782849A3 (en) * | 1999-04-12 | 2007-05-23 | Theregen, Inc. | Three-dimensional stromal tissue |
DE19919625C2 (de) * | 1999-04-29 | 2002-10-31 | Symetis Ag Zuerich | In-vitro-Verfahren zum Herstellen einer homologen Herzklappe und durch dieses Verfahren herstellbare Klappe |
DE19922078A1 (de) * | 1999-05-15 | 2000-11-23 | Weitzel Kage Doris | Gewebekonstrukt für die Transplantationschirurgie |
EP1210038A1 (de) * | 1999-08-20 | 2002-06-05 | Peter Metz-Stavenhagen | Wirbelsäulensegment |
DE19949290A1 (de) * | 1999-10-12 | 2001-04-26 | Albrecht Bettermann | Partikuläres Konstrukt zur Verwendung in der Transplantationsmedizin |
US6576265B1 (en) | 1999-12-22 | 2003-06-10 | Acell, Inc. | Tissue regenerative composition, method of making, and method of use thereof |
US6376244B1 (en) * | 1999-12-29 | 2002-04-23 | Children's Medical Center Corporation | Methods and compositions for organ decellularization |
US6479064B1 (en) * | 1999-12-29 | 2002-11-12 | Children's Medical Center Corporation | Culturing different cell populations on a decellularized natural biostructure for organ reconstruction |
US20030124099A1 (en) * | 1999-12-29 | 2003-07-03 | Anthony Atala | Augmentation of organ function |
DE10026480A1 (de) * | 2000-05-29 | 2001-12-13 | Augustinus Bader | Verfahren zur Herstellung eines empfängerspezifischen Gewebe-Transplantats oder -Implantats |
DE10026482A1 (de) * | 2000-05-29 | 2001-12-13 | Augustinus Bader | Verfahren zur Herstellung eines bioartifiziellen Transplantats |
DK1290145T3 (da) | 2000-05-31 | 2006-03-13 | Fraunhofer Ges Forschung | Tredimensional hudmodel |
DE10034583A1 (de) * | 2000-07-14 | 2002-01-31 | Axel Haverich | Individuelle Venenklappenprothese |
US6599526B2 (en) * | 2000-08-18 | 2003-07-29 | The University Of North Texas Health Science Center At Fort Worth | Pericardial anti-adhesion patch |
DE10041468C1 (de) * | 2000-08-23 | 2002-03-07 | Surface Care Gmbh | Hautmatrix zur Abdeckung und Regenerierung verletzter Hautpartien sowie Verfahren zu ihrer Herstellung |
DE10047300A1 (de) * | 2000-09-25 | 2002-04-18 | Gustav Steinhoff | Bioartifizielles Verbundmaterial und Verfahren zu seiner Herstellung |
DE10058240A1 (de) * | 2000-11-17 | 2002-05-29 | Auto Tissue Gmbh | Verfahren und Vorrichtung zur Herstellung biologischer Prothesen |
DE10064948C1 (de) | 2000-12-20 | 2002-07-11 | Auto Tissue Gmbh | Verfahren zur Dezellularisierung von Fremdmaterial zur Herstellung von Bioprothesen und Vorrichtung zur Durchführung des Verfahrens |
DE10106512C1 (de) * | 2001-02-13 | 2002-05-23 | Axel Haverich | Verfahren zur Herstellung eines biologischen Gewebes unter Verwendung einer Kollagenunterlage und zugehöriges Gewebekonstrukt |
ES2272365T5 (es) | 2001-02-13 | 2011-04-26 | Corlife Gbr | Matriz de tejido bioartificial vascularizada primariamente y tejido bioartificial vascularizado primariamente. |
DE10138564B4 (de) * | 2001-08-06 | 2007-07-12 | Lamm, Peter Wilhelm, Dr. | Verfahren zur Devitalisierung natürlicher Organe und/oder zur Bereitstellung extrazellulärer Matrices zum "Tissue-Engineering" |
DE10146903C1 (de) * | 2001-09-24 | 2002-11-14 | Cytonet Gmbh & Co Kg | Verfahren zur Herstellung von in vitro-Hohlorganen |
EP1317934A1 (de) * | 2001-11-08 | 2003-06-11 | Artiss GmbH | Verfahren zur Herstellung einer azellularisierten Gewebematrix und damit erhältliche Gewebematrix |
DE10156561A1 (de) * | 2001-11-20 | 2003-05-28 | Artiss Gmbh | Bioartifizielles Trachea-Implantat und Verfahren zu seiner Herstellung |
DE10217779A1 (de) * | 2002-04-18 | 2003-11-13 | Co Don Ag | Konservierte Gewebematrix eines Hohlorganes, insbesondere eines Blutgefäßes, Verfahren zur Herstellung und Verwendung dieser |
DE10235237A1 (de) * | 2002-08-01 | 2004-02-12 | Symetis Ag | In-vitro-Verfahren zum Herstellen einer homologen "gestenteten" Tissue eingineerten Herzklappe |
US20040175366A1 (en) * | 2003-03-07 | 2004-09-09 | Acell, Inc. | Scaffold for cell growth and differentiation |
EP1644011A1 (en) | 2003-06-25 | 2006-04-12 | Stephen F. Badylak | Conditioned matrix compositions for tissue restoration |
PL1699915T3 (pl) | 2003-12-30 | 2010-11-30 | Augustinus Bader | Zastosowanie erytropoetyny do regeneracji tkanki wątrobowej |
EP1693025A1 (en) | 2005-02-17 | 2006-08-23 | Universität Zürich | Method of manufacturing a tissue-engineered prosthesis |
CN1903144A (zh) * | 2005-07-29 | 2007-01-31 | 广东冠昊生物科技有限公司 | 生物型人工韧带及其制备方法 |
US10590391B2 (en) | 2007-06-08 | 2020-03-17 | Wake Forest University Health Sciences | Selective cell therapy for the treatment of renal failure |
CN103865871A (zh) | 2007-06-08 | 2014-06-18 | 韦克福里斯特大学健康科学院 | 治疗肾功能衰竭的选择性细胞疗法 |
WO2010057015A1 (en) | 2008-11-14 | 2010-05-20 | Wake Forest University Health Sciences | Kidney structures and methods of forming the same |
KR101029887B1 (ko) * | 2009-03-04 | 2011-04-18 | 서울대학교산학협력단 | 탈세포화를 위한 돼지 각막의 가공방법 |
JP5526573B2 (ja) * | 2009-03-26 | 2014-06-18 | 国立大学法人 東京医科歯科大学 | 脱細胞化生体組織の調製方法 |
EP2417247A1 (en) | 2009-04-09 | 2012-02-15 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Cellular seeding and co-culture of a three dimensional fibroblast construct |
US8298586B2 (en) | 2009-07-22 | 2012-10-30 | Acell Inc | Variable density tissue graft composition |
US8652500B2 (en) | 2009-07-22 | 2014-02-18 | Acell, Inc. | Particulate tissue graft with components of differing density and methods of making and using the same |
DE102010020222A1 (de) | 2010-05-11 | 2011-11-17 | Axel Haverich | Verfahren zur Herstellung einer Organnachbildung, insbesondere eines Funktionsmodells |
US10207025B2 (en) | 2011-04-28 | 2019-02-19 | Lifecell Corporation | Method for enzymatic treatment of tissue products |
AU2012249538B2 (en) * | 2011-04-28 | 2016-01-28 | Lifecell Corporation | Method for enzymatic treatment of tissue products |
EP2995325B1 (en) | 2013-05-07 | 2020-01-15 | National University Corporation Tokyo Medical and Dental University | Method for preparing particulate decellularized tissue |
AU2014341866B2 (en) | 2013-11-04 | 2018-07-05 | Lifecell Corporation | Methods of removing alpha-galactose |
EP3782629A1 (en) | 2015-02-27 | 2021-02-24 | Adeka Corporation | Decellularized tissue |
JP6793113B2 (ja) | 2015-03-12 | 2020-12-02 | Kmバイオロジクス株式会社 | 脱細胞化組織を用いた癒着防止材及び代用生体膜 |
JP6712160B2 (ja) * | 2016-03-29 | 2020-06-17 | 株式会社Adeka | エンドトキシン測定のための前処理方法及びその測定方法 |
AU2018212908A1 (en) | 2017-01-30 | 2019-08-08 | Lifecell Corporation | Transglutaminase treated products |
CA3051245A1 (en) | 2017-01-30 | 2018-08-02 | Lifecell Corporation | Tissue matrix materials and enzymatic adhesives |
JPWO2018221402A1 (ja) | 2017-05-30 | 2020-04-30 | 株式会社Adeka | 移植用脱細胞化材料の製造方法及び当該材料を含む生体適合性材料からなる移植片組成物 |
SG11201912185XA (en) | 2017-06-16 | 2020-01-30 | Avery Therapeutics Inc | Three dimensional tissue compositions and methods of use |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2678945B2 (ja) * | 1989-04-17 | 1997-11-19 | 有限会社ナイセム | 人工血管とその製造方法及び人工血管用基質 |
US5336616A (en) * | 1990-09-12 | 1994-08-09 | Lifecell Corporation | Method for processing and preserving collagen-based tissues for transplantation |
US5192312A (en) * | 1991-03-05 | 1993-03-09 | Colorado State University Research Foundation | Treated tissue for implantation and methods of treatment and use |
EP1452153A1 (en) * | 1994-03-14 | 2004-09-01 | Cryolife, Inc | Treated tissue for implantation and preparation methods |
EP0781116A4 (en) * | 1994-09-12 | 1999-08-25 | Advanced Tissue Sciences Inc | THREE-DIMENSIONAL CULTURES OF HUMAN CELLS ON HEART VALVE FRAME AND THEIR USE |
AU5564996A (en) * | 1995-04-19 | 1996-11-07 | St. Jude Medical Inc. | Matrix substrate for a viable body tissue-derived prosthesis and method for making the same |
-
1998
- 1998-06-29 ES ES98941248T patent/ES2175753T3/es not_active Expired - Lifetime
- 1998-06-29 DE DE19828726A patent/DE19828726A1/de not_active Withdrawn
- 1998-06-29 WO PCT/DE1998/001782 patent/WO1999000152A2/de active IP Right Grant
- 1998-06-29 JP JP50521599A patent/JP2002507907A/ja active Pending
- 1998-06-29 DE DE59803925T patent/DE59803925D1/de not_active Expired - Fee Related
- 1998-06-29 EP EP98941248A patent/EP0989867B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1999000152A3 (de) | 1999-05-27 |
WO1999000152A2 (de) | 1999-01-07 |
JP2002507907A (ja) | 2002-03-12 |
EP0989867B1 (de) | 2002-04-24 |
DE59803925D1 (de) | 2002-05-29 |
EP0989867A2 (de) | 2000-04-05 |
DE19828726A1 (de) | 1999-01-07 |
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Legal Events
Date | Code | Title | Description |
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FG2A | Definitive protection |
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