ES2171976T3 - Formulacion de ciclosporina. - Google Patents

Formulacion de ciclosporina.

Info

Publication number
ES2171976T3
ES2171976T3 ES97934627T ES97934627T ES2171976T3 ES 2171976 T3 ES2171976 T3 ES 2171976T3 ES 97934627 T ES97934627 T ES 97934627T ES 97934627 T ES97934627 T ES 97934627T ES 2171976 T3 ES2171976 T3 ES 2171976T3
Authority
ES
Spain
Prior art keywords
pct
sec
date
cyclosporine formulation
pub
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97934627T
Other languages
English (en)
Inventor
Milan Stuchlik
Tomas Andrysek
Alexander Jegorov
Ales Husek
Vladimir Matha
Josef Stuchlik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ivax Pharmaceuticals sro
Original Assignee
Ivax CR AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax CR AS filed Critical Ivax CR AS
Application granted granted Critical
Publication of ES2171976T3 publication Critical patent/ES2171976T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

COMPOSICION FARMACEUTICA PARA USO INTERNO QUE CONTIENE, COMO INGREDIENTE ACTIVO, DE UN 10 A UN 25% EN PESO DE UNA CICLOSPORINA, Y UN VEHICULO COMPUESTO POR (I) UNO O MAS ESTERES PARCIALES DE ACIDO GRASO C 16 A C 22 , CON UN DERIVADO D EL GLICEROL SELECCIONADO ENTRE: DIGLICEROL A DECAGLICEROL, Y (II) ESTERES PARCIALES DE ACIDOS GRASOS C 8 A C 16 CON PENTAGLICEROL A PENTADECAGLICEROL, EN RELACIONES MUTUAS PONDERALES (I):(II) DE 1:1 A 1:5, CONTENIENDO OPTATIVAMENTE ADYUVANTES ADICIONALES.
ES97934627T 1996-08-01 1997-07-31 Formulacion de ciclosporina. Expired - Lifetime ES2171976T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CZ19962289A CZ288739B6 (cs) 1996-08-01 1996-08-01 Cyklosporin obsahující léčivé přípravky

Publications (1)

Publication Number Publication Date
ES2171976T3 true ES2171976T3 (es) 2002-09-16

Family

ID=5464691

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97934627T Expired - Lifetime ES2171976T3 (es) 1996-08-01 1997-07-31 Formulacion de ciclosporina.

Country Status (11)

Country Link
US (2) US6106860A (es)
EP (1) EP0917460B1 (es)
KR (1) KR100495417B1 (es)
AT (1) ATE213643T1 (es)
AU (1) AU3777197A (es)
CZ (1) CZ288739B6 (es)
DE (1) DE69710732T2 (es)
DK (1) DK0917460T3 (es)
ES (1) ES2171976T3 (es)
PT (1) PT917460E (es)
WO (1) WO1998005309A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
CZ288739B6 (cs) * 1996-08-01 2001-08-15 Galena, A. S. Cyklosporin obsahující léčivé přípravky
SE511313C2 (sv) * 1997-01-13 1999-09-06 Gs Dev Ab Komposition med reglerad frisättning innefattande fettsyraester av diacylglycerol
GB9811854D0 (en) * 1998-06-02 1998-07-29 Ciba Geigy Ag Organic compounds
AUPP627498A0 (en) 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
GB2355656B (en) * 1999-08-17 2004-04-07 Galena As Pharmaceutical compositions for oral and topical administration
AU2002333098B2 (en) * 2001-10-19 2006-03-16 Isotechnika Pharma Inc. Novel cyclosporin analog microemulsion preconcentrates
GB2391473B (en) * 2002-08-02 2004-07-07 Satishchandra Punambhai Patel Pharmaceutical compositions
WO2004050688A1 (en) 2002-12-02 2004-06-17 Xenome Ltd NOVEL χ-CONOTOXIN PEPTIDES (-II)
ATE547424T1 (de) 2002-12-02 2012-03-15 Xenome Ltd Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure
KR100884189B1 (ko) * 2007-06-20 2009-02-18 심종원 치아세정수단의 탈부착이 가능한 샤워기

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat
CZ288631B6 (cs) * 1996-01-18 2001-08-15 Galena, A. S. Léčivé přípravky s obsahem cyklosporinu
CZ288739B6 (cs) * 1996-08-01 2001-08-15 Galena, A. S. Cyklosporin obsahující léčivé přípravky

Also Published As

Publication number Publication date
US6312721B1 (en) 2001-11-06
CZ228996A3 (cs) 1998-02-18
EP0917460B1 (en) 2002-02-27
WO1998005309A1 (en) 1998-02-12
AU3777197A (en) 1998-02-25
US6106860A (en) 2000-08-22
KR20000029746A (ko) 2000-05-25
DE69710732D1 (de) 2002-04-04
CZ288739B6 (cs) 2001-08-15
DE69710732T2 (de) 2002-10-17
ATE213643T1 (de) 2002-03-15
KR100495417B1 (ko) 2005-06-14
PT917460E (pt) 2002-07-31
DK0917460T3 (da) 2002-03-25
EP0917460A1 (en) 1999-05-26

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