ATE547424T1 - Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure - Google Patents

Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure

Info

Publication number
ATE547424T1
ATE547424T1 AT03812100T AT03812100T ATE547424T1 AT E547424 T1 ATE547424 T1 AT E547424T1 AT 03812100 T AT03812100 T AT 03812100T AT 03812100 T AT03812100 T AT 03812100T AT E547424 T1 ATE547424 T1 AT E547424T1
Authority
AT
Austria
Prior art keywords
cys
xaa1
terminal
peptides
amino acid
Prior art date
Application number
AT03812100T
Other languages
English (en)
Inventor
Richard Lewis
Paul Alewood
Dianne Alewood
Elka Palant
Original Assignee
Xenome Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenome Ltd filed Critical Xenome Ltd
Application granted granted Critical
Publication of ATE547424T1 publication Critical patent/ATE547424T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT03812100T 2002-12-02 2003-12-02 Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure ATE547424T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43030602P 2002-12-02 2002-12-02
PCT/AU2003/001605 WO2004050690A1 (en) 2002-12-02 2003-12-02 NOVEL χ-CONOTOXIN PEPTIDES (-I)

Publications (1)

Publication Number Publication Date
ATE547424T1 true ATE547424T1 (de) 2012-03-15

Family

ID=32469446

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03812100T ATE547424T1 (de) 2002-12-02 2003-12-02 Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure

Country Status (14)

Country Link
US (1) US7851444B2 (de)
EP (1) EP1572725B1 (de)
JP (1) JP4565087B2 (de)
AT (1) ATE547424T1 (de)
AU (1) AU2003302609B9 (de)
CA (1) CA2508129C (de)
CY (1) CY1112839T1 (de)
DK (1) DK1572725T3 (de)
ES (1) ES2383358T3 (de)
HK (1) HK1080870A1 (de)
NZ (1) NZ540518A (de)
PT (1) PT1572725E (de)
SI (1) SI1572725T1 (de)
WO (1) WO2004050690A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP627498A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
WO2004050688A1 (en) * 2002-12-02 2004-06-17 Xenome Ltd NOVEL χ-CONOTOXIN PEPTIDES (-II)
US8062623B2 (en) * 2004-10-15 2011-11-22 Velocys Stable, catalyzed, high temperature combustion in microchannel, integrated combustion reactors
WO2007047373A1 (en) * 2005-10-13 2007-04-26 Velocys, Inc. Microchannel apparatus comprising a platinum aluminide layer and chemical processes using the apparatus
CN102752032B (zh) * 2011-04-22 2015-04-22 艾利森电话股份有限公司 同频负载均衡方法及其设备
US10519324B2 (en) 2015-05-22 2019-12-31 Clemson University Research Foundation Conotoxin peptides for use in biofouling deterrence

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051403A (en) 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
ZA921292B (en) 1991-02-25 1993-08-23 Lilly Co Eli Treatment of lower urinary tract disorders.
WO1993013128A1 (en) 1991-12-30 1993-07-08 Neurex Corporation Methods of producing analgesia and enhancing opiate analgesia
HUT77283A (hu) 1994-11-03 1998-03-30 Novartis Ag. Egyszerű összetételű, a hatóanyagot biológiailag jól hozzáférhetően tartalmazó, orális alkalmazásra szánt új ciklosporinkészítmény és eljárás az előállítására
AU6047996A (en) 1995-06-07 1996-12-30 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin formulations as agents for immunosuppr ession and multiple drug resistant indications
EP0835126B1 (de) 1995-06-27 2003-04-02 Elan Pharmaceuticals, Inc. Zusammensetzungen zur erzielung von analgesie und zur hemmung der progression neuropathischer schmerzerkrankungen
ZA971525B (en) 1996-02-22 1997-10-21 Neurosearch As Tropane derivatives, their preparation and use.
GB9614902D0 (en) 1996-07-16 1996-09-04 Rhodes John Sustained release composition
CZ288739B6 (cs) 1996-08-01 2001-08-15 Galena, A. S. Cyklosporin obsahující léčivé přípravky
AU735724B2 (en) 1996-11-18 2001-07-12 University Of Utah Research Foundation Use of conotoxin peptides ImI and MII as cardiovascular agents
EP0981515B1 (de) 1997-05-14 2003-08-27 Neurosearch A/S Piperidine derivate als inhibitoren der neurotransmitter-wiederaufbaunahme
AUPP627498A0 (en) 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
US6767896B1 (en) * 1999-01-29 2004-07-27 Cognetix, Inc. Conotoxin peptides
AU3473800A (en) 1999-01-29 2000-08-18 University Of Utah Research Foundation Conotoxin peptides
US20010036943A1 (en) 2000-04-07 2001-11-01 Coe Jotham W. Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines
US20030170222A1 (en) * 2001-01-29 2003-09-11 University Of Utah Research Foundation Beta-superfamily conotoxins
US20030109670A1 (en) * 2001-02-09 2003-06-12 University Of Utah Research Foundation Cone snail peptides
WO2004050688A1 (en) 2002-12-02 2004-06-17 Xenome Ltd NOVEL χ-CONOTOXIN PEPTIDES (-II)

Also Published As

Publication number Publication date
AU2003302609A1 (en) 2004-06-23
AU2003302609B9 (en) 2008-05-15
JP4565087B2 (ja) 2010-10-20
WO2004050690A1 (en) 2004-06-17
EP1572725B1 (de) 2012-02-29
HK1080870A1 (en) 2006-05-04
CA2508129A1 (en) 2004-06-17
CY1112839T1 (el) 2016-02-10
JP2006523181A (ja) 2006-10-12
SI1572725T1 (sl) 2012-08-31
EP1572725A4 (de) 2008-09-24
AU2003302609B2 (en) 2008-03-20
PT1572725E (pt) 2012-05-28
NZ540518A (en) 2006-12-22
DK1572725T3 (da) 2012-06-18
US20060142201A1 (en) 2006-06-29
ES2383358T3 (es) 2012-06-20
CA2508129C (en) 2012-06-26
US7851444B2 (en) 2010-12-14
EP1572725A1 (de) 2005-09-14

Similar Documents

Publication Publication Date Title
CY1112839T1 (el) Πεπτιδια χ-κωνοτοξινες που εχουν ενα αμινοτελικο πυρογλουταμικο οξυ
PH12012502372A1 (en) Hla-a*3303-restricted wt1 peptide and pharmaceutical composition comprising the same
NL300013I1 (nl) Nieuwe protein met TNF-remmende werking en hun ber
EP0333356A3 (de) Hirudin-Peptide
HK1154211A1 (zh) 預防和減少失血和炎症反應
ATE171712T1 (de) Neuartiger menschlicher proteaseinhibitor vom kunitz-typ und entsprechende varianten
ATE152129T1 (de) Inhibitorvarianten der menschlichen protease vom kunitz-typ
WO2011038900A3 (en) Peptide analogues of glucagon for diabetes therapy
ATE278708T1 (de) Conotoxin peptid pviia
AU5963290A (en) Inhibition of the n-end rule pathway in living cells
DE69827262D1 (de) Penaeidine: antimikrobielle peptide aus krebstieren
WO2004014937A3 (en) Thrombin peptide derivatives
JP2006523181A5 (de)
AR009805A1 (es) Peptidos que contienen cisteina
NZ332946A (en) Modified forms of interleukin-5 molecules capable of antagonising of IL-5
DE60326726D1 (de) Peptide mit affinität für ein phospholipid und deren verwendung
CA2446390A1 (en) Antigenic epitopes of factor viii, inhibitors directed against said epitopes and use thereof
WO1999057262A3 (de) An metallionen bindendes peptid
EA199900432A1 (ru) Ice-ингибирующие пептиды
AU2003260306A1 (en) Bicyclic oligopeptides