WO1999057262A3 - An metallionen bindendes peptid - Google Patents

An metallionen bindendes peptid Download PDF

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Publication number
WO1999057262A3
WO1999057262A3 PCT/EP1999/003076 EP9903076W WO9957262A3 WO 1999057262 A3 WO1999057262 A3 WO 1999057262A3 EP 9903076 W EP9903076 W EP 9903076W WO 9957262 A3 WO9957262 A3 WO 9957262A3
Authority
WO
WIPO (PCT)
Prior art keywords
terminal
amino acids
lys
leu
sequence
Prior art date
Application number
PCT/EP1999/003076
Other languages
English (en)
French (fr)
Other versions
WO1999057262A2 (de
Inventor
Joern Gloekler
Original Assignee
Biotechnolog Forschung Gmbh
Joern Gloekler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotechnolog Forschung Gmbh, Joern Gloekler filed Critical Biotechnolog Forschung Gmbh
Publication of WO1999057262A2 publication Critical patent/WO1999057262A2/de
Publication of WO1999057262A3 publication Critical patent/WO1999057262A3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Die Erfindung betrifft ein an Fe(III) bindendes Peptid mit einer Aminosäuresequenz aus der folgenden Gruppe von Sequenzen: (i) Arg Pro Thr Lys Lys Phe Thr Leu Thr His Lys His Ser Lys Arg, wobei diese Sequenz N-terminal um 1, 2 oder 3 Aminosäuren und/oder C-terminal um eine Aminosäure deletiert sein kann, (ii) Gly Ile Pro Ala His Glu Gln His Thr Lys Lys Leu Trp Leu Leu, wobei diese Sequenz N-terminal um 1, 2, 3 oder 4 und/oder C-terminal um 1, 2, 3 oder 4 Aminosäuren deletiert sein kann, und (iii) Ile Ser Leu Ser Asn His Arg Met Gln Trp His His Asn Tyr Ser, wobei diese Sequenz N-terminal um 1, 2, 3, 4 oder 5 Aminosäuren und/oder C-terminal um 1, 2 oder 3 Aminosäuren deletiert sein kann.
PCT/EP1999/003076 1998-05-05 1999-05-05 An metallionen bindendes peptid WO1999057262A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1998119843 DE19819843A1 (de) 1998-05-05 1998-05-05 Metallchelat bindende Peptide
DE19819843.4 1998-05-05

Publications (2)

Publication Number Publication Date
WO1999057262A2 WO1999057262A2 (de) 1999-11-11
WO1999057262A3 true WO1999057262A3 (de) 1999-12-23

Family

ID=7866610

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/003076 WO1999057262A2 (de) 1998-05-05 1999-05-05 An metallionen bindendes peptid

Country Status (2)

Country Link
DE (1) DE19819843A1 (de)
WO (1) WO1999057262A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110049875A (ko) 1999-10-01 2011-05-12 디엠아이 바이오사이언시스, 인크 금속 결합 화합물 및 그의 용도
WO2003078451A2 (en) * 2002-03-13 2003-09-25 New Century Pharmaceuticals, Inc. Method of isolating binding peptides from a combinatorial phage display library and peptides produced thereby
AU2006239721B2 (en) 2005-04-26 2011-07-14 Boehringer Ingelheim Rcv Gmbh & Co Kg Production of recombinant proteins by autoproteolytic cleavage of a fusion protein

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0282042A2 (de) * 1987-03-10 1988-09-14 F. Hoffmann-La Roche Ag Neue Fusionsproteine und deren Reinigung
EP0497585A2 (de) * 1991-01-30 1992-08-05 Leslie Deriemer Anderson Verfahren zur Immobilisierung und Vernetzung von Proteinen und sonstigen Molekülen, und dessen Verwendung

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0282042A2 (de) * 1987-03-10 1988-09-14 F. Hoffmann-La Roche Ag Neue Fusionsproteine und deren Reinigung
EP0497585A2 (de) * 1991-01-30 1992-08-05 Leslie Deriemer Anderson Verfahren zur Immobilisierung und Vernetzung von Proteinen und sonstigen Molekülen, und dessen Verwendung

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GOUD, GADDAM NARSA ET AL: "Selection of specific peptide ligands for immobilized metals using a phage displayed library: application to protein separation using IMAC", INT. J. BIO-CHROMATOGR. (1997), 3(2), 123-136, XP002119173 *
PATWARDHAN A V ET AL: "Selection of optimum affinity tags from a phage-displayed peptide library Application to immobilized copper(II) affinity chromatography", JOURNAL OF CHROMATOGRAPHY A, vol. 787, no. 1-2, 7 November 1997 (1997-11-07), pages 91-100, XP004097592, ISSN: 0021-9673 *

Also Published As

Publication number Publication date
WO1999057262A2 (de) 1999-11-11
DE19819843A1 (de) 1999-11-11

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