AR009805A1 - Peptidos que contienen cisteina - Google Patents
Peptidos que contienen cisteinaInfo
- Publication number
- AR009805A1 AR009805A1 ARP970104369A ARP970104369A AR009805A1 AR 009805 A1 AR009805 A1 AR 009805A1 AR P970104369 A ARP970104369 A AR P970104369A AR P970104369 A ARP970104369 A AR P970104369A AR 009805 A1 AR009805 A1 AR 009805A1
- Authority
- AR
- Argentina
- Prior art keywords
- pro
- proline
- side chains
- amino acid
- glu
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Un péptido fisiologicamente activo de formula (I): A-(R1)x-R2-Cys-R3-B, en la cual cada A se selecciona independientemente entre H, un grupo protector, opor lo menos un residuo aminoácido seleccionado independientemente entre el grupo de residuos aminoácidos que tienen cadenas laterales alifáticas, cadenaslaterales oxhidrilo alifáticas, cadenas laterales básicas, cadenas laterales acídicas, grupos amino secundario, cadenas laterales amida, cadenas lateralesaromáticas y cadenas lateralescon contenido de azufre; x es 0 (estando ausente R1) y R2 y R3 son residuos de aminoácidos seleccionados entre una de lassiguientes combinaciones (a) y (b) de aminoácidos: (a) R2 leucina (Leu), R3 fenilalanina (Phe); (b) R2 glutamina (Gln), R3 alanina (Ala), o x es 1, y R1,y R2 y R3 son residuos de aminoácidos elegidos entre una de las siguientes combinaciones (c) y (f) a (s) de aminoácidos: (c) R1 ácido glutámico (Glu), R2prolina (Pro), R3 metionina (Met); (f) R1 alanina (Ala), R2 prolina (Pro), R3 metionina (Met); (g) R1 ácido glutámico (Glu), R2 prolina (Pro), R3 triptofano(Trp); (h) R1 serina (Ser), R2 prolina (Pro), R3 triptofano (Trp), (i) R1 leucina (Leu), R2 leucina (Leu), R3 glicina (Gly); (j) R1 prolina (Pro), R2arginina (Arg), R3 arginina (Arg); (k) R1 glicina (Gly), R2 tirosina (Tyr), R3 prolina (Pro); (l) R1 valina (Val), R2 valina (Val), R3 asparagina (Asn); (m)R1 alanina (Ala), R2 leucina (Leu), R3 arginina (Arg); (n) R1 glicina (Gly), R2 alanina (Ala),R3 prolina (Pro); (o) R1 lisina (Lys), R2 serina (Ser), R3lisina (Lys); (p) R1 ácido glutámico (Glu), R2 (Pro), R3 fenilalanina (Phe); (q) R1 ácido glutámico (Glu), R2 prolina (Pro), R3 tirosina (Tyr); (r) R1serina (Ser), R2 prolina (Pro), R3 metionina (Met); (s) R1 glicina (Gly), R2 prolina (Pro), R3 triptofano (Trp); con las condiciones de que, cuando x es O
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9603466A SE9603466D0 (sv) | 1996-09-23 | 1996-09-23 | New compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
AR009805A1 true AR009805A1 (es) | 2000-05-03 |
Family
ID=20403988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970104369A AR009805A1 (es) | 1996-09-23 | 1997-09-23 | Peptidos que contienen cisteina |
Country Status (5)
Country | Link |
---|---|
AR (1) | AR009805A1 (es) |
AU (1) | AU4406197A (es) |
SE (1) | SE9603466D0 (es) |
WO (1) | WO1998012213A2 (es) |
ZA (1) | ZA978477B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4674231B2 (ja) | 2004-03-01 | 2011-04-20 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 2量体小分子アポトーシス増強剤 |
MX2009010667A (es) * | 2007-04-12 | 2010-02-24 | Joyant Pharmaceuticals Inc | Dimeros y trimeros mimeticos de smac utiles como agentes anti-cancer. |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0142387A1 (en) * | 1983-08-26 | 1985-05-22 | Anda Biologicals | Process for the preparation of vaccines specific for LH and HCG and process for their detection |
US5270170A (en) * | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
ES2142867T3 (es) * | 1992-04-13 | 2000-05-01 | Oklahoma Med Res Found | Procedimientos y reactivos para el diagnostico de autoanticuerpos. |
CA2144180A1 (en) * | 1992-09-08 | 1994-03-17 | George A. Heavner | Peptide inhibitors of cellular adhesion |
SE9403526D0 (sv) * | 1994-10-14 | 1994-10-14 | Astra Ab | New Peptides |
WO1996013589A1 (en) * | 1994-10-27 | 1996-05-09 | Immulogic Pharmaceutical Corporation | T cell epitopes of the major allergens from ambrosia artemisiifolia |
EP0923604A1 (en) * | 1996-04-12 | 1999-06-23 | Astra Aktiebolag | Cysteine-containing or methioine-containing peptides with immunomodulatory effects |
-
1996
- 1996-09-23 SE SE9603466A patent/SE9603466D0/xx unknown
-
1997
- 1997-09-15 WO PCT/SE1997/001552 patent/WO1998012213A2/en active Application Filing
- 1997-09-15 AU AU44061/97A patent/AU4406197A/en not_active Abandoned
- 1997-09-19 ZA ZA9708477A patent/ZA978477B/xx unknown
- 1997-09-23 AR ARP970104369A patent/AR009805A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
ZA978477B (en) | 1998-03-23 |
SE9603466D0 (sv) | 1996-09-23 |
WO1998012213A2 (en) | 1998-03-26 |
WO1998012213A3 (en) | 1998-04-30 |
AU4406197A (en) | 1998-04-14 |
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