WO1998012213A3 - Cysteine containing peptides - Google Patents

Cysteine containing peptides Download PDF

Info

Publication number
WO1998012213A3
WO1998012213A3 PCT/SE1997/001552 SE9701552W WO9812213A3 WO 1998012213 A3 WO1998012213 A3 WO 1998012213A3 SE 9701552 W SE9701552 W SE 9701552W WO 9812213 A3 WO9812213 A3 WO 9812213A3
Authority
WO
WIPO (PCT)
Prior art keywords
peptides
containing peptides
cysteine containing
heterodimers
absorbable
Prior art date
Application number
PCT/SE1997/001552
Other languages
French (fr)
Other versions
WO1998012213A2 (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to AU44061/97A priority Critical patent/AU4406197A/en
Publication of WO1998012213A2 publication Critical patent/WO1998012213A2/en
Publication of WO1998012213A3 publication Critical patent/WO1998012213A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Physiologically active peptides of the formula (I): A-(-R1-)-xR2-Cys-R3-B, wherein each variable has the meaning defined in the description, the entire peptide sequence containing up to 20 amino acid residues; and homo- or heterodimers thereof. These peptides are absorbable by the epithelial cell lining in a mammal resulting in a modulated immune response and thereby a therapeutic effect against disease.
PCT/SE1997/001552 1996-09-23 1997-09-15 Cysteine containing peptides WO1998012213A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU44061/97A AU4406197A (en) 1996-09-23 1997-09-15 Cysteine containing peptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9603466-5 1996-09-23
SE9603466A SE9603466D0 (en) 1996-09-23 1996-09-23 New compounds

Publications (2)

Publication Number Publication Date
WO1998012213A2 WO1998012213A2 (en) 1998-03-26
WO1998012213A3 true WO1998012213A3 (en) 1998-04-30

Family

ID=20403988

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SE1997/001552 WO1998012213A2 (en) 1996-09-23 1997-09-15 Cysteine containing peptides

Country Status (5)

Country Link
AR (1) AR009805A1 (en)
AU (1) AU4406197A (en)
SE (1) SE9603466D0 (en)
WO (1) WO1998012213A2 (en)
ZA (1) ZA978477B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4674231B2 (en) * 2004-03-01 2011-04-20 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Dimer small molecule apoptosis enhancer
BRPI0810178A2 (en) * 2007-04-12 2014-09-23 Joyant Pharmaceuticals Inc SMAC MIME DIMERS AND THERMALS USEFUL AS ANTICCAN AGENTS

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0142387A1 (en) * 1983-08-26 1985-05-22 Anda Biologicals Process for the preparation of vaccines specific for LH and HCG and process for their detection
WO1993008278A1 (en) * 1991-10-16 1993-04-29 Affymax Technologies N.V. Peptide library and screening method
WO1993021223A1 (en) * 1992-04-13 1993-10-28 Board Of Regents Of The University Of Oklahoma Methods and reagents for diagnosis of autoantibodies
WO1994005310A1 (en) * 1992-09-08 1994-03-17 Centocor, Inc. Peptide inhibitors of cellular adhesion
WO1996011943A1 (en) * 1994-10-14 1996-04-25 Astra Aktiebolag New peptides with immunomodulatory effects
WO1996013589A1 (en) * 1994-10-27 1996-05-09 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from ambrosia artemisiifolia
WO1997039023A1 (en) * 1996-04-12 1997-10-23 Astra Aktiebolag Cysteine-containing or methioine-containing peptides with immunomodulatory effects

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0142387A1 (en) * 1983-08-26 1985-05-22 Anda Biologicals Process for the preparation of vaccines specific for LH and HCG and process for their detection
WO1993008278A1 (en) * 1991-10-16 1993-04-29 Affymax Technologies N.V. Peptide library and screening method
WO1993021223A1 (en) * 1992-04-13 1993-10-28 Board Of Regents Of The University Of Oklahoma Methods and reagents for diagnosis of autoantibodies
WO1994005310A1 (en) * 1992-09-08 1994-03-17 Centocor, Inc. Peptide inhibitors of cellular adhesion
WO1996011943A1 (en) * 1994-10-14 1996-04-25 Astra Aktiebolag New peptides with immunomodulatory effects
WO1996013589A1 (en) * 1994-10-27 1996-05-09 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from ambrosia artemisiifolia
WO1997039023A1 (en) * 1996-04-12 1997-10-23 Astra Aktiebolag Cysteine-containing or methioine-containing peptides with immunomodulatory effects

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DHAWAN E.A.: "A novel peptide from amyloid P component supports cell attachment", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 171, no. 3, 1990, ORLANDO, FL US, pages 1284 - 1290, XP000147513 *
KAISER E.A.: "Racemization studies of Fmoc-Cys-Trt-OH during stepwise Fmoc solid phase peptide synthesis", TETRAHEDRON LETTERS, vol. 37, no. 8, 19 February 1996 (1996-02-19), pages 1187 - 1190, XP002051996 *

Also Published As

Publication number Publication date
SE9603466D0 (en) 1996-09-23
ZA978477B (en) 1998-03-23
WO1998012213A2 (en) 1998-03-26
AU4406197A (en) 1998-04-14
AR009805A1 (en) 2000-05-03

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