SE9603466D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE9603466D0
SE9603466D0 SE9603466A SE9603466A SE9603466D0 SE 9603466 D0 SE9603466 D0 SE 9603466D0 SE 9603466 A SE9603466 A SE 9603466A SE 9603466 A SE9603466 A SE 9603466A SE 9603466 D0 SE9603466 D0 SE 9603466D0
Authority
SE
Sweden
Prior art keywords
new compounds
peptides
heterodimers
absorbable
cys
Prior art date
Application number
SE9603466A
Other languages
Swedish (sv)
Inventor
Haakan Bergstrand
Tomas Eriksson
Magnus Lindvall
Bengt Saernstrand
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9603466A priority Critical patent/SE9603466D0/en
Publication of SE9603466D0 publication Critical patent/SE9603466D0/en
Priority to PCT/SE1997/001552 priority patent/WO1998012213A2/en
Priority to AU44061/97A priority patent/AU4406197A/en
Priority to ZA9708477A priority patent/ZA978477B/en
Priority to ARP970104369A priority patent/AR009805A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Physiologically active peptides of the formula (I): A-(-R1-)-xR2-Cys-R3-B, wherein each variable has the meaning defined in the description, the entire peptide sequence containing up to 20 amino acid residues; and homo- or heterodimers thereof. These peptides are absorbable by the epithelial cell lining in a mammal resulting in a modulated immune response and thereby a therapeutic effect against disease.
SE9603466A 1996-09-23 1996-09-23 New compounds SE9603466D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
SE9603466A SE9603466D0 (en) 1996-09-23 1996-09-23 New compounds
PCT/SE1997/001552 WO1998012213A2 (en) 1996-09-23 1997-09-15 Cysteine containing peptides
AU44061/97A AU4406197A (en) 1996-09-23 1997-09-15 Cysteine containing peptides
ZA9708477A ZA978477B (en) 1996-09-23 1997-09-19 Cysteine containing peptides.
ARP970104369A AR009805A1 (en) 1996-09-23 1997-09-23 PEPTIDES CONTAINING CYSTEINE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9603466A SE9603466D0 (en) 1996-09-23 1996-09-23 New compounds

Publications (1)

Publication Number Publication Date
SE9603466D0 true SE9603466D0 (en) 1996-09-23

Family

ID=20403988

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9603466A SE9603466D0 (en) 1996-09-23 1996-09-23 New compounds

Country Status (5)

Country Link
AR (1) AR009805A1 (en)
AU (1) AU4406197A (en)
SE (1) SE9603466D0 (en)
WO (1) WO1998012213A2 (en)
ZA (1) ZA978477B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4674231B2 (en) 2004-03-01 2011-04-20 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Dimer small molecule apoptosis enhancer
MX2009010667A (en) * 2007-04-12 2010-02-24 Joyant Pharmaceuticals Inc Smac mimetic dimers and trimers useful as anti-cancer agents.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0142387A1 (en) * 1983-08-26 1985-05-22 Anda Biologicals Process for the preparation of vaccines specific for LH and HCG and process for their detection
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
ES2142867T3 (en) * 1992-04-13 2000-05-01 Oklahoma Med Res Found PROCEDURES AND REAGENTS FOR THE DIAGNOSIS OF AUTOANTIBODIES.
CA2144180A1 (en) * 1992-09-08 1994-03-17 George A. Heavner Peptide inhibitors of cellular adhesion
SE9403526D0 (en) * 1994-10-14 1994-10-14 Astra Ab New Peptides
WO1996013589A1 (en) * 1994-10-27 1996-05-09 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from ambrosia artemisiifolia
EP0923604A1 (en) * 1996-04-12 1999-06-23 Astra Aktiebolag Cysteine-containing or methioine-containing peptides with immunomodulatory effects

Also Published As

Publication number Publication date
ZA978477B (en) 1998-03-23
WO1998012213A2 (en) 1998-03-26
WO1998012213A3 (en) 1998-04-30
AU4406197A (en) 1998-04-14
AR009805A1 (en) 2000-05-03

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