ES2170083T3 - Analizador con un dispositivo para la separacion de microparticulas magneticas. - Google Patents
Analizador con un dispositivo para la separacion de microparticulas magneticas.Info
- Publication number
- ES2170083T3 ES2170083T3 ES94113653T ES94113653T ES2170083T3 ES 2170083 T3 ES2170083 T3 ES 2170083T3 ES 94113653 T ES94113653 T ES 94113653T ES 94113653 T ES94113653 T ES 94113653T ES 2170083 T3 ES2170083 T3 ES 2170083T3
- Authority
- ES
- Spain
- Prior art keywords
- magnetic microparticles
- separation
- reaction vessel
- analyzer
- magnets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/005—Pretreatment specially adapted for magnetic separation
- B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0474—Details of actuating means for conveyors or pipettes
- G01N2035/0482—Transmission
- G01N2035/0484—Belt or chain
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/109—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Soft Magnetic Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
Abstract
APARATO DE ANALISIS CON UN DISPOSITIVO PARA LA SEPARACION DE MICROPARTICULAS MAGNETICAS A PARTIR DE UNA SUSPENSION, DONDE EL DISPOSITIVO DE SEPARACION CONTIENE DOS IMANES (41,61) Y (42,62) PERMANENTES, ENTRE LOS CUALES SE ENCUENTRA UN RECIPIENTE (8) DE REACCION QUE CONTIENE UNA SUSPENSION. PARA UNA SEPARACION RAPIDA Y COMPLETA DE LAS MICROPARTICULAS (27), LOS IMANES (41, 61) Y (42,62) CON RELACION AL RECIPIENTE (8) DE REACCION SE ENCUENTRAN COLOCADOS DE FORMA OPUESTA DIAMETRALMENTE Y LOS EJES (47) POLARES, EL IMAN (41,61), EL IMAN (42,62) Y EL EJE (48) LONGITUDINAL DEL RECIPIENTE (8) DE REACCION FORMAN UN ANGULO (ALFA) AGUDO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH280193 | 1993-09-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2170083T3 true ES2170083T3 (es) | 2002-08-01 |
Family
ID=4241900
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94113653T Expired - Lifetime ES2170083T3 (es) | 1993-09-17 | 1994-09-01 | Analizador con un dispositivo para la separacion de microparticulas magneticas. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5705062A (es) |
EP (1) | EP0644425B1 (es) |
JP (1) | JP2825768B2 (es) |
AT (1) | ATE212723T1 (es) |
CA (1) | CA2131843A1 (es) |
DE (1) | DE59410037D1 (es) |
ES (1) | ES2170083T3 (es) |
Families Citing this family (84)
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US20030127396A1 (en) * | 1995-02-21 | 2003-07-10 | Siddiqi Iqbal Waheed | Apparatus and method for processing magnetic particles |
US6884357B2 (en) | 1995-02-21 | 2005-04-26 | Iqbal Waheed Siddiqi | Apparatus and method for processing magnetic particles |
DE19512368A1 (de) * | 1995-04-01 | 1996-10-02 | Boehringer Mannheim Gmbh | System zur Freisetzung und Isolierung von Nukleinsäuren |
US6919175B1 (en) | 1995-04-01 | 2005-07-19 | Roche Diagnostics Gmbh | System for releasing and isolating nucleic acids |
US6299839B1 (en) * | 1995-08-31 | 2001-10-09 | First Medical, Inc. | System and methods for performing rotor assays |
DE69638151D1 (de) * | 1996-05-20 | 2010-04-29 | Prec System Science Co Ltd | Prozess und apparat zur kontrolle magnetischer teilchen mit hilfe einer pipettier-maschine |
US6558947B1 (en) | 1997-09-26 | 2003-05-06 | Applied Chemical & Engineering Systems, Inc. | Thermal cycler |
US6106784A (en) * | 1997-09-26 | 2000-08-22 | Applied Chemical & Engineering Systems, Inc. | Thawing station |
DE69839294T2 (de) * | 1997-09-29 | 2009-04-09 | F. Hoffmann-La Roche Ag | Gerät zur Abscheidung magnetischer Teilchen |
JP4431276B2 (ja) * | 1998-03-19 | 2010-03-10 | プレシジョン・システム・サイエンス株式会社 | 磁性粒子処理集積化装置及びその制御方法 |
EP1930078A1 (en) | 1998-05-01 | 2008-06-11 | Gen-Probe Incorporated | Method for agitating the contents of a container |
US8337753B2 (en) | 1998-05-01 | 2012-12-25 | Gen-Probe Incorporated | Temperature-controlled incubator having a receptacle mixing mechanism |
WO1999061919A2 (en) * | 1998-05-22 | 1999-12-02 | Nichols Institute Diagnostics | Magnetic particle suspending device, apparatus and methods for using same |
DE19823719B4 (de) * | 1998-05-27 | 2011-12-15 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren zum Aufkonzentrieren von Substanzen |
ATE303598T1 (de) * | 1998-07-31 | 2005-09-15 | Tecan Trading Ag | Magnetseparator |
US6776174B2 (en) * | 1998-08-21 | 2004-08-17 | Paul E. Nisson | Apparatus for washing magnetic particles |
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US6672458B2 (en) * | 2000-05-19 | 2004-01-06 | Becton, Dickinson And Company | System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample |
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WO1992005443A1 (en) * | 1990-09-15 | 1992-04-02 | Medical Research Council | Reagent separation |
JP2548626B2 (ja) * | 1990-11-21 | 1996-10-30 | 三井製薬工業株式会社 | 免疫自動分析装置 |
JPH04271823A (ja) * | 1991-02-26 | 1992-09-28 | Kyoto Daiichi Kagaku:Kk | セル内液体の撹拌装置 |
EP0589636B1 (en) * | 1992-09-24 | 2000-08-02 | Amersham Pharmacia Biotech UK Limited | Magnetic separation method and apparatus therefor |
-
1994
- 1994-09-01 ES ES94113653T patent/ES2170083T3/es not_active Expired - Lifetime
- 1994-09-01 AT AT94113653T patent/ATE212723T1/de not_active IP Right Cessation
- 1994-09-01 DE DE59410037T patent/DE59410037D1/de not_active Expired - Lifetime
- 1994-09-01 EP EP94113653A patent/EP0644425B1/de not_active Expired - Lifetime
- 1994-09-07 US US08/301,857 patent/US5705062A/en not_active Expired - Lifetime
- 1994-09-12 CA CA002131843A patent/CA2131843A1/en not_active Abandoned
- 1994-09-16 JP JP6221895A patent/JP2825768B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0644425A1 (de) | 1995-03-22 |
DE59410037D1 (de) | 2002-03-14 |
JPH07181188A (ja) | 1995-07-21 |
JP2825768B2 (ja) | 1998-11-18 |
US5705062A (en) | 1998-01-06 |
ATE212723T1 (de) | 2002-02-15 |
EP0644425B1 (de) | 2002-01-30 |
CA2131843A1 (en) | 1995-03-18 |
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