ES2169223T3 - Substancia anticancerosa que inhibe la metastasis cancerosa. - Google Patents
Substancia anticancerosa que inhibe la metastasis cancerosa.Info
- Publication number
- ES2169223T3 ES2169223T3 ES96901963T ES96901963T ES2169223T3 ES 2169223 T3 ES2169223 T3 ES 2169223T3 ES 96901963 T ES96901963 T ES 96901963T ES 96901963 T ES96901963 T ES 96901963T ES 2169223 T3 ES2169223 T3 ES 2169223T3
- Authority
- ES
- Spain
- Prior art keywords
- metastasis
- cancerose
- target substance
- substance inhibiting
- cancer cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010027476 Metastases Diseases 0.000 title abstract 4
- 230000009401 metastasis Effects 0.000 title abstract 4
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000013076 target substance Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000009291 secondary effect Effects 0.000 abstract 1
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
- C07H7/027—Keto-aldonic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA PRESENTE INVENCION ESTA DIRIGIDA A LA DESCRIPCION DE UN AGENTE ANTICANCEROSO QUE PUEDE INHIBIR LA METASTASIS DE CELULAS CANCEROSAS CUANDO SE UTILIZA POR SI SOLO. ADEMAS, LA PRESENTE INVENCION TAMBIEN ESTA DIRIGIDA A LA DESCRIPCION DE UN AGENTE ANTICANCEROSO QUE PUEDE INHIBIR LA METASTASIS DE CELULAS CANCEROSAS PROVOCANDO UN PEQUEÑO EFECTO SECUNDARIO Y MUY POCA TOXICIDAD INCLUSO DURANTE UN LARGO TIEMPO DE ADMINISTRACION. EL AGENTE ANTICANCEROSO QUE INHIBE LA METASTASIS CANCEROSA SEGUN LA PRESENTE INVENCION SE CARACTERIZA PORQUE CONTIENE ACIDO SIALICO, SU SAL, UN POLIMERO DEL ACIDO SIALICO O UNA SAL DEL POLIMERO COMO UN INGREDIENTE EFICAZ.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP1996/000268 WO1997028807A1 (fr) | 1996-02-08 | 1996-02-08 | Substance anticancereuse inhibant le processus metastatique cancereux |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2169223T3 true ES2169223T3 (es) | 2002-07-01 |
Family
ID=14152897
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96901963T Expired - Lifetime ES2169223T3 (es) | 1996-02-08 | 1996-02-08 | Substancia anticancerosa que inhibe la metastasis cancerosa. |
Country Status (7)
Country | Link |
---|---|
US (1) | US6083931A (es) |
EP (1) | EP0821963B1 (es) |
KR (1) | KR19980703698A (es) |
CA (1) | CA2217710C (es) |
DE (1) | DE69617415T2 (es) |
ES (1) | ES2169223T3 (es) |
WO (1) | WO1997028807A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2800984B1 (fr) | 1999-11-17 | 2001-12-14 | Jacques Seguin | Dispositif de remplacement d'une valve cardiaque par voie percutanee |
US20070043435A1 (en) | 1999-11-17 | 2007-02-22 | Jacques Seguin | Non-cylindrical prosthetic valve system for transluminal delivery |
US7018406B2 (en) | 1999-11-17 | 2006-03-28 | Corevalve Sa | Prosthetic valve for transluminal delivery |
CN101641061B (zh) | 2006-12-06 | 2013-12-18 | 美顿力科尔瓦有限责任公司 | 用于环锚固的自膨胀瓣膜的经心尖递送的系统和方法 |
US8475523B2 (en) | 2010-02-17 | 2013-07-02 | Medtronic, Inc. | Distal tip assembly for a heart valve delivery catheter |
US8518106B2 (en) | 2010-02-17 | 2013-08-27 | Medtronic, Inc. | Catheter assembly with valve crimping accessories |
US8926693B2 (en) | 2010-02-17 | 2015-01-06 | Medtronic, Inc. | Heart valve delivery catheter with safety button |
US9414914B2 (en) | 2010-02-24 | 2016-08-16 | Medtronic Ventor Technologies Ltd. | Catheter assembly with valve crimping accessories |
US9545306B2 (en) | 2010-04-21 | 2017-01-17 | Medtronic, Inc. | Prosthetic valve with sealing members and methods of use thereof |
US9387077B2 (en) | 2010-05-27 | 2016-07-12 | Medtronic Vascular Galway | Catheter assembly with prosthesis crimping and prosthesis retaining accessories |
FR3034642B1 (fr) | 2015-04-07 | 2021-01-15 | Benjamin Faurie | Introducteur pour ensemble de remplacement d'une valve cardiaque ou pour ensemble d'angioplastie coronaire |
ES2892273T3 (es) | 2016-10-07 | 2022-02-03 | Electroducer | Conjunto de sustitución de una válvula cardíaca o de un conjunto de angioplastia coronaria |
WO2019185880A1 (fr) | 2018-03-29 | 2019-10-03 | Electroducer | Ensemble de pose d'un implant cardiaque, aortique ou arteriel avec assistance de stimulation par catheter pour voie arterielle ou veineuse peripherique |
FR3079404B1 (fr) | 2018-03-29 | 2020-03-06 | Electroducer | Ensemble de remplacement d’une valve cardiaque avec assistance de stimulation par voie arterielle ou veineuse peripherique |
JP2021042189A (ja) * | 2019-09-06 | 2021-03-18 | 均 石井 | 抗がん剤。 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60190791A (ja) * | 1984-03-09 | 1985-09-28 | Kanto Ishi Pharma Co Ltd | シアル酸誘導体およびその製造法 |
JPS6183125A (ja) * | 1984-09-28 | 1986-04-26 | Kanto Ishi Pharma Co Ltd | 癌転移阻害剤 |
JPS62132895A (ja) * | 1985-12-05 | 1987-06-16 | Mect Corp | 癌転移阻害剤の製造方法 |
JPH0684307B2 (ja) * | 1986-03-26 | 1994-10-26 | メクト株式会社 | 新規癌転移阻害剤 |
JPH03245784A (ja) * | 1990-02-23 | 1991-11-01 | Toshiba Corp | モータ制御装置 |
US5438125A (en) * | 1991-03-06 | 1995-08-01 | Nippon Zoki Pharmaceutical Co., Ltd. | Sialic acid derivatives |
ATE338762T1 (de) * | 1991-04-19 | 2006-09-15 | Univ Leland Stanford Junior | Zusammensetzungen und methoden für die verknüpfung von endothelzellen |
EP0521692A3 (en) * | 1991-07-02 | 1993-02-03 | The Biomembrane Institute | Inhibition of tumor cell metastasis potential and invasiveness by chemically-defined oligosaccharides, their derivatives, mimetics and antibodies directed to them |
JPH06245784A (ja) * | 1993-02-19 | 1994-09-06 | Taiyo Kagaku Co Ltd | シアル酸及びシアル酸誘導体含有組成物の製造方法 |
GB9422584D0 (en) * | 1994-02-15 | 1995-01-04 | Medical Res Council | Immunomodulation using oligosaccharides |
-
1996
- 1996-02-08 ES ES96901963T patent/ES2169223T3/es not_active Expired - Lifetime
- 1996-02-08 DE DE69617415T patent/DE69617415T2/de not_active Expired - Fee Related
- 1996-02-08 EP EP96901963A patent/EP0821963B1/en not_active Expired - Lifetime
- 1996-02-08 KR KR1019970707098A patent/KR19980703698A/ko not_active Application Discontinuation
- 1996-02-08 CA CA002217710A patent/CA2217710C/en not_active Expired - Fee Related
- 1996-02-08 US US08/930,680 patent/US6083931A/en not_active Expired - Fee Related
- 1996-02-08 WO PCT/JP1996/000268 patent/WO1997028807A1/ja active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
KR19980703698A (ko) | 1998-12-05 |
CA2217710C (en) | 2002-05-28 |
DE69617415D1 (de) | 2002-01-10 |
WO1997028807A1 (fr) | 1997-08-14 |
EP0821963B1 (en) | 2001-11-28 |
DE69617415T2 (de) | 2002-08-01 |
EP0821963A1 (en) | 1998-02-04 |
US6083931A (en) | 2000-07-04 |
EP0821963A4 (en) | 1999-07-14 |
CA2217710A1 (en) | 1997-08-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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