ES2164672T3 - Disminucion del efecto de hook en ensayos inmunitarios con un material de soporte en forma de particulas. - Google Patents

Disminucion del efecto de hook en ensayos inmunitarios con un material de soporte en forma de particulas.

Info

Publication number
ES2164672T3
ES2164672T3 ES94104525T ES94104525T ES2164672T3 ES 2164672 T3 ES2164672 T3 ES 2164672T3 ES 94104525 T ES94104525 T ES 94104525T ES 94104525 T ES94104525 T ES 94104525T ES 2164672 T3 ES2164672 T3 ES 2164672T3
Authority
ES
Spain
Prior art keywords
analyte
support material
hook
particles
decrease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94104525T
Other languages
English (en)
Inventor
Geoffrey Dr Burns
Wolf-Dieter Dr Engel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of ES2164672T3 publication Critical patent/ES2164672T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA DETERMINACION DE UNA ANALITICA EN UN LIQUIDO DE PRUEBA MEDIANTE LA UNION DE LA PRUEBA EN UN RECEPTOR R1 CON CAPACIDAD DE UNION ESPECIFICA CON LA PRUEBA, QUE ESTA INMOVILIZADO SOBRE UN MATERIAL SOPORTE EN FORMA DE PARTICULAS, QUE SE ENCUENTRA EN EL LIQUIDO DE PRUEBA, CARACTERIZANDOSE PORQUE, EL LIQUIDO DE PRUEBA CONTIENE ADEMAS UN RECEPTOR R2 SOLUBLE, CON CAPACIDAD DE UNION ESPECIFICA CON LA PRUEBA, POSEYENDO AL MENOS DOS LUGARES DE UNION PARA LA MUESTRA. OTRO OBJETIVO DE LA UNION ES UN REACTIVO PARA LA REALIZACION DEL PROCEDIMIENTO ANTES INDICADO.
ES94104525T 1993-03-23 1994-03-22 Disminucion del efecto de hook en ensayos inmunitarios con un material de soporte en forma de particulas. Expired - Lifetime ES2164672T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4309393A DE4309393A1 (de) 1993-03-23 1993-03-23 Verringerung des Hook-Effekts in Immuntests mit teilchenförmigem Trägermaterial

Publications (1)

Publication Number Publication Date
ES2164672T3 true ES2164672T3 (es) 2002-03-01

Family

ID=6483613

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94104525T Expired - Lifetime ES2164672T3 (es) 1993-03-23 1994-03-22 Disminucion del efecto de hook en ensayos inmunitarios con un material de soporte en forma de particulas.

Country Status (5)

Country Link
EP (1) EP0617285B1 (es)
JP (1) JP2688402B2 (es)
AT (1) ATE208900T1 (es)
DE (2) DE4309393A1 (es)
ES (1) ES2164672T3 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19521388C2 (de) * 1995-06-13 1997-05-22 Immuno Gmbh Technik zur Bestimmung einer spezifisch-bindefähigen Substanz
JPH1026621A (ja) * 1996-07-12 1998-01-27 Dai Ichi Pure Chem Co Ltd イムノアッセイ法
DE19637418A1 (de) * 1996-09-13 1998-03-19 Boehringer Mannheim Gmbh Homogene Nachweisverfahren zur Bestimmung von Subpopulationen eines Analyten
TW591230B (en) * 1997-10-14 2004-06-11 Bayer Ag Method for improving the accuracy of the semi-quantitative determination of analyte in fluid samples
ATE221657T1 (de) * 1998-05-06 2002-08-15 Roche Diagnostics Gmbh Entstörung durch rheumafaktoren
GB0027064D0 (en) * 2000-11-06 2000-12-20 Randox Lab Ltd Multi-analyte immunoassay
DE10064827A1 (de) 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
US8367013B2 (en) 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US6837171B1 (en) 2002-04-29 2005-01-04 Palmer/Snyder Furniture Company Lightweight table with unitized table top
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US7781172B2 (en) 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US7247500B2 (en) * 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
WO2005062048A1 (de) 2003-12-01 2005-07-07 Dade Behring Marburg Gmbh Homogenes nachweisverfahren
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
JP4755112B2 (ja) * 2004-12-24 2011-08-24 積水メディカル株式会社 抗原を測定するための試薬及び抗原の測定方法
AU2006313611B2 (en) * 2005-11-12 2013-01-31 Platform Diagnostics Limited Agglutination assay
CA2686427C (en) * 2007-05-08 2013-07-16 F. Hoffmann-La Roche Ag Method for the detection of specific immunoglobulin class g antibodies
WO2016208421A1 (ja) * 2015-06-24 2016-12-29 コニカミノルタ株式会社 測定方法、並びにこれに用いる測定チップ、及び測定用キット

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS585659A (ja) * 1981-06-24 1983-01-13 ハイブリテツク　インコ−ポレ−テツド 単クロ−ン性抗体を使用する免疫学的、抑制試験
JPS5992353A (ja) * 1982-11-19 1984-05-28 Shinotesuto Kenkyusho:Kk 不溶性担体粒子を用いる凝集反応測定方法
US4595661A (en) * 1983-11-18 1986-06-17 Beckman Instruments, Inc. Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect
JPH067130B2 (ja) * 1986-01-17 1994-01-26 株式会社ミドリ十字 凝集反応試験用水性溶媒
DE3633497A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Immunometrisches bestimmungsverfahren
JPH01301165A (ja) * 1988-05-30 1989-12-05 Sekisui Chem Co Ltd 免疫測定法
FR2652900B1 (fr) * 1989-10-11 1994-01-28 Clonatec Sa Procede d'analyse immunologique de type "sandwich" son application au depistage prenatal in vitro de la trisomie 21 et necessaire pour sa mise en óoeuvre.
DE4034509A1 (de) * 1990-10-30 1992-05-07 Boehringer Mannheim Gmbh Immunologisches praezipitationsverfahren zur bestimmung eines bindefaehigen analyten sowie reagenz zur durchfuehrung dieses verfahrens
JPH04344465A (ja) * 1991-05-22 1992-12-01 Canon Inc 免疫測定法
DE4218257A1 (de) * 1992-06-03 1993-12-09 Behringwerke Ag Verfahren zur immunchemischen Bestimmung eines Analyten

Also Published As

Publication number Publication date
DE4309393A1 (de) 1994-09-29
JP2688402B2 (ja) 1997-12-10
EP0617285A3 (en) 1995-09-20
DE59409947D1 (de) 2001-12-20
ATE208900T1 (de) 2001-11-15
JPH06324043A (ja) 1994-11-25
EP0617285A2 (de) 1994-09-28
EP0617285B1 (de) 2001-11-14

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