ES2163650T3 - Sintesis de hidrosulfonas y compuestos relacionados. - Google Patents
Sintesis de hidrosulfonas y compuestos relacionados.Info
- Publication number
- ES2163650T3 ES2163650T3 ES96928260T ES96928260T ES2163650T3 ES 2163650 T3 ES2163650 T3 ES 2163650T3 ES 96928260 T ES96928260 T ES 96928260T ES 96928260 T ES96928260 T ES 96928260T ES 2163650 T3 ES2163650 T3 ES 2163650T3
- Authority
- ES
- Spain
- Prior art keywords
- synthesis
- hydrosulphones
- related compounds
- carbonic
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 3
- 238000003786 synthesis reaction Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 abstract 2
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- IAVUPMFITXYVAF-XPUUQOCRSA-N dorzolamide Chemical compound CCN[C@H]1C[C@H](C)S(=O)(=O)C2=C1C=C(S(N)(=O)=O)S2 IAVUPMFITXYVAF-XPUUQOCRSA-N 0.000 abstract 1
- 229960003933 dorzolamide Drugs 0.000 abstract 1
- 230000004410 intraocular pressure Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Casings For Electric Apparatus (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
ESTA INVENCION CONCIERNE A UN PROCESO MEJORADO PARA LA SINTESIS DE HIDROXISULFONA, QUE ES UN INTERMEDIARIO CLAVE EN LA SINTESIS DE LOS INHIBIDORES DE LA ANHIDRASA CARBONICA, ESPECIALMENTE DORZOLAMIDA. LOS INHIBIDORES DE LA ANHIDRASA CARBONICA SE SABE QUE SON EFICACES EN EL TRATAMIENTO DE LA PRESION INTRAOCULAR ELEVADA O GLAUCOMA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US289095P | 1995-08-29 | 1995-08-29 | |
GBGB9602852.7A GB9602852D0 (en) | 1996-02-13 | 1996-02-13 | Synthesis of hydroxysulfone and related compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2163650T3 true ES2163650T3 (es) | 2002-02-01 |
Family
ID=26308662
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96928260T Expired - Lifetime ES2163650T3 (es) | 1995-08-29 | 1996-08-26 | Sintesis de hidrosulfonas y compuestos relacionados. |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0853625B1 (es) |
JP (1) | JP3396484B2 (es) |
KR (1) | KR100297188B1 (es) |
CN (1) | CN1200125A (es) |
AT (1) | ATE208394T1 (es) |
AU (1) | AU705740B2 (es) |
BR (1) | BR9610282A (es) |
CA (1) | CA2229233C (es) |
CZ (1) | CZ59698A3 (es) |
DE (1) | DE69616811T2 (es) |
DK (1) | DK0853625T3 (es) |
EA (1) | EA001246B1 (es) |
ES (1) | ES2163650T3 (es) |
HU (1) | HUP9901543A3 (es) |
NZ (1) | NZ315966A (es) |
PL (1) | PL325120A1 (es) |
PT (1) | PT853625E (es) |
RO (1) | RO119148B1 (es) |
SK (1) | SK23498A3 (es) |
TW (1) | TW432067B (es) |
UA (1) | UA52619C2 (es) |
WO (1) | WO1997008173A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2128161A1 (en) * | 2008-05-30 | 2009-12-02 | Ragactives, S.L. | Process for obtaining 4-hydroxy-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-7,7-dioxide and its enantiomers, and applications thereof |
CN108822125B (zh) * | 2018-05-30 | 2020-01-31 | 沈阳药科大学 | 1-(噻吩并[2,3-b]噻喃甲酰基)-4-脂肪烃基哌嗪类化合物及其医药用途 |
CN108822127B (zh) * | 2018-05-30 | 2020-05-15 | 沈阳药科大学 | 4-羟亚胺基噻吩并[2,3-b]噻喃-2-甲酰胺类化合物及其用途 |
-
1996
- 1996-08-23 TW TW085110312A patent/TW432067B/zh active
- 1996-08-26 PL PL96325120A patent/PL325120A1/xx unknown
- 1996-08-26 PT PT96928260T patent/PT853625E/pt unknown
- 1996-08-26 UA UA98031547A patent/UA52619C2/uk unknown
- 1996-08-26 HU HU9901543A patent/HUP9901543A3/hu unknown
- 1996-08-26 RO RO98-00294A patent/RO119148B1/ro unknown
- 1996-08-26 BR BR9610282A patent/BR9610282A/pt not_active Application Discontinuation
- 1996-08-26 ES ES96928260T patent/ES2163650T3/es not_active Expired - Lifetime
- 1996-08-26 AT AT96928260T patent/ATE208394T1/de active
- 1996-08-26 WO PCT/US1996/013634 patent/WO1997008173A1/en not_active Application Discontinuation
- 1996-08-26 CN CN96197718A patent/CN1200125A/zh active Pending
- 1996-08-26 SK SK234-98A patent/SK23498A3/sk unknown
- 1996-08-26 CZ CZ98596A patent/CZ59698A3/cs unknown
- 1996-08-26 DE DE69616811T patent/DE69616811T2/de not_active Expired - Lifetime
- 1996-08-26 EA EA199800236A patent/EA001246B1/ru not_active IP Right Cessation
- 1996-08-26 AU AU67803/96A patent/AU705740B2/en not_active Ceased
- 1996-08-26 EP EP96928260A patent/EP0853625B1/en not_active Expired - Lifetime
- 1996-08-26 NZ NZ315966A patent/NZ315966A/xx unknown
- 1996-08-26 KR KR1019980701448A patent/KR100297188B1/ko not_active IP Right Cessation
- 1996-08-26 JP JP51045497A patent/JP3396484B2/ja not_active Expired - Fee Related
- 1996-08-26 DK DK96928260T patent/DK0853625T3/da active
- 1996-08-26 CA CA002229233A patent/CA2229233C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
HUP9901543A1 (hu) | 1999-09-28 |
BR9610282A (pt) | 1999-03-16 |
PL325120A1 (en) | 1998-07-06 |
JPH11510190A (ja) | 1999-09-07 |
CZ59698A3 (cs) | 1998-07-15 |
EA199800236A1 (ru) | 1998-10-29 |
KR100297188B1 (ko) | 2001-10-26 |
CA2229233A1 (en) | 1997-03-06 |
CA2229233C (en) | 2003-10-07 |
EP0853625B1 (en) | 2001-11-07 |
DK0853625T3 (da) | 2001-12-27 |
EA001246B1 (ru) | 2000-12-25 |
KR19990044212A (ko) | 1999-06-25 |
AU705740B2 (en) | 1999-06-03 |
ATE208394T1 (de) | 2001-11-15 |
WO1997008173A1 (en) | 1997-03-06 |
CN1200125A (zh) | 1998-11-25 |
DE69616811D1 (de) | 2001-12-13 |
PT853625E (pt) | 2002-03-28 |
TW432067B (en) | 2001-05-01 |
JP3396484B2 (ja) | 2003-04-14 |
NZ315966A (en) | 1999-11-29 |
UA52619C2 (uk) | 2003-01-15 |
EP0853625A1 (en) | 1998-07-22 |
HUP9901543A3 (en) | 2000-03-28 |
AU6780396A (en) | 1997-03-19 |
SK23498A3 (en) | 1998-08-05 |
DE69616811T2 (de) | 2002-05-29 |
RO119148B1 (ro) | 2004-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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