ES2158684T3 - Procedimiento para la preparacion de acido 3,4-epoxibutirico quiral y sus sales. - Google Patents

Procedimiento para la preparacion de acido 3,4-epoxibutirico quiral y sus sales.

Info

Publication number
ES2158684T3
ES2158684T3 ES98929880T ES98929880T ES2158684T3 ES 2158684 T3 ES2158684 T3 ES 2158684T3 ES 98929880 T ES98929880 T ES 98929880T ES 98929880 T ES98929880 T ES 98929880T ES 2158684 T3 ES2158684 T3 ES 2158684T3
Authority
ES
Spain
Prior art keywords
acid
preparation
epoxibutric
salts
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98929880T
Other languages
English (en)
Inventor
Il-Suk Byun
Kyung-Il Kim
Yoon-Hwan Choi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lotte Fine Chemical Co Ltd
Original Assignee
Samsung Fine Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samsung Fine Chemicals Co Ltd filed Critical Samsung Fine Chemicals Co Ltd
Application granted granted Critical
Publication of ES2158684T3 publication Critical patent/ES2158684T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La invención se refiere al procedimiento para la preparación del ácido quiral 3,4-epoxibutírico representado por la fórmula (1) y la sal de éste, en el que se emplea como materia prima la hidroxibutirolactona-(S)-3-activada u otro material barato para realizar una reacción eficaz de apertura de anillo y una epoxidación con una inversión del centro quiral.
ES98929880T 1997-07-16 1998-06-17 Procedimiento para la preparacion de acido 3,4-epoxibutirico quiral y sus sales. Expired - Lifetime ES2158684T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR19970033208 1997-07-16
KR1019970057812A KR100247563B1 (ko) 1997-07-16 1997-11-03 키랄3,4-에폭시부티르산및이의염의제조방법

Publications (1)

Publication Number Publication Date
ES2158684T3 true ES2158684T3 (es) 2001-09-01

Family

ID=26632933

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98929880T Expired - Lifetime ES2158684T3 (es) 1997-07-16 1998-06-17 Procedimiento para la preparacion de acido 3,4-epoxibutirico quiral y sus sales.

Country Status (9)

Country Link
US (1) US6232478B1 (es)
EP (1) EP1000049B1 (es)
JP (1) JP3306549B2 (es)
KR (1) KR100247563B1 (es)
CN (1) CN1264372A (es)
CA (1) CA2296316A1 (es)
DE (1) DE69800805T2 (es)
ES (1) ES2158684T3 (es)
WO (1) WO1999003850A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100255039B1 (ko) * 1997-07-28 2000-05-01 박영구 L-카르니틴의제조방법
US20100108118A1 (en) * 2008-06-02 2010-05-06 Daniel Luch Photovoltaic power farm structure and installation
US20090293941A1 (en) * 2008-06-02 2009-12-03 Daniel Luch Photovoltaic power farm structure and installation
KR20000065995A (ko) * 1999-04-12 2000-11-15 박영구 키랄 3-히드록시-γ-부티로락톤의 제조방법
EP2298759A1 (en) 2002-08-30 2011-03-23 Memory Pharmaceuticals Corporation Anabaseine derivatives useful in the treatment of neurodegenerative diseases
PL210065B1 (pl) 2002-09-25 2011-11-30 Memory Pharm Corp Związki indazole, benzotiazole i benzoizotiazole, kompozycje farmaceutyczne je zawierające oraz zastosowanie związków
US7767828B2 (en) 2003-11-12 2010-08-03 Phenomix Corporation Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7576121B2 (en) 2003-11-12 2009-08-18 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7317109B2 (en) 2003-11-12 2008-01-08 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7674913B2 (en) 2003-11-12 2010-03-09 Phenomix Corporation Heterocyclic boronic acid compounds
CA2560741C (en) 2004-03-25 2013-08-06 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
US7825139B2 (en) 2005-05-25 2010-11-02 Forest Laboratories Holdings Limited (BM) Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US9865758B2 (en) 2006-04-13 2018-01-09 Daniel Luch Collector grid and interconnect structures for photovoltaic arrays and modules
US9236512B2 (en) 2006-04-13 2016-01-12 Daniel Luch Collector grid and interconnect structures for photovoltaic arrays and modules
CA2674084C (en) 2006-12-26 2013-05-14 Pharmacyclics, Inc. Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy
CL2008000119A1 (es) 2007-01-16 2008-05-16 Wyeth Corp Compuestos derivados de pirazol, antagonistas del receptor nicotinico de acetilcolina; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como demencia senil, alzheimer y esquizofrenia.
CN102374987A (zh) * 2010-08-17 2012-03-14 上海新先锋药业有限公司 一种4-乙酰氧基氮杂环丁酮中间体的含量测定方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1189069B (it) * 1986-03-14 1988-01-28 Donegani Guido Ist Processo per la preparazione biotecnologica della l(-)-carnitina cloruro
JP2834501B2 (ja) * 1989-11-25 1998-12-09 鐘淵化学工業株式会社 ３，４―エポキシ酪酸エステルの製法および中間体
CA2049536C (en) 1991-05-13 1999-07-06 Rawle I. Hollingsworth Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof

Also Published As

Publication number Publication date
CN1264372A (zh) 2000-08-23
JP3306549B2 (ja) 2002-07-24
KR19990013236A (ko) 1999-02-25
KR100247563B1 (ko) 2000-04-01
EP1000049A1 (en) 2000-05-17
JP2001508082A (ja) 2001-06-19
CA2296316A1 (en) 1999-01-28
DE69800805D1 (de) 2001-06-21
WO1999003850A1 (en) 1999-01-28
EP1000049B1 (en) 2001-05-16
US6232478B1 (en) 2001-05-15
DE69800805T2 (de) 2001-11-15

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