ES2157963T3 - Nueva secuencia pro que permite la secrecion de proteinas heterologas a partir de una celula de levadura. - Google Patents
Nueva secuencia pro que permite la secrecion de proteinas heterologas a partir de una celula de levadura.Info
- Publication number
- ES2157963T3 ES2157963T3 ES94400062T ES94400062T ES2157963T3 ES 2157963 T3 ES2157963 T3 ES 2157963T3 ES 94400062 T ES94400062 T ES 94400062T ES 94400062 T ES94400062 T ES 94400062T ES 2157963 T3 ES2157963 T3 ES 2157963T3
- Authority
- ES
- Spain
- Prior art keywords
- pro sequence
- yeast cell
- allows
- section
- new pro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Insects & Arthropods (AREA)
- Wood Science & Technology (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UNA NUEVA SECUENCIA PRO PERMITIENDO LA SINTESIS Y LA SECRECION DE PROTEINAS HETEROLOGAS A PARTIR DE UNA CELULA DE LEVADURA, MAS ESPECIALMENTE UNA LEVADURA DE LA CLASE SACCHAROMYCES TERRANOVAE. LA NUEVA SECUENCIA PRO SE DERIVA DEL PRECURSOR DE LA "DEFENSINA A" DE INSECTO PHORMIA TERRANOVAE. LA PRESENTE INVENCION SE REFIERE A UNA CASSETTE DE EXPRESION, UN VECTOR ASI COMO UNA CELULA DE LEVADURA COMPRENDIENDO UN FRAGMENTO DE ADN CODIFICANDO PARA LA CITADA SECUENCIA PRO Y UN PROCEDIMIENTO DE PREPARACION DE PROTEINAS HETEROLOGAS PONIENDO EN PRACTICA UNA TAL SECUENCIA PRO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9300171A FR2700338B1 (fr) | 1993-01-11 | 1993-01-11 | Nouvelle séquence pro permettant la secrétion de protéines hétérologues à partir d'une cellule de levure. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2157963T3 true ES2157963T3 (es) | 2001-09-01 |
Family
ID=9442934
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94400062T Expired - Lifetime ES2157963T3 (es) | 1993-01-11 | 1994-01-11 | Nueva secuencia pro que permite la secrecion de proteinas heterologas a partir de una celula de levadura. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0607080B1 (es) |
AT (1) | ATE202381T1 (es) |
DE (1) | DE69427496T2 (es) |
DK (1) | DK0607080T3 (es) |
ES (1) | ES2157963T3 (es) |
FR (1) | FR2700338B1 (es) |
GR (1) | GR3036648T3 (es) |
PT (1) | PT607080E (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2157261T3 (es) * | 1993-06-29 | 2001-08-16 | Transgene Sa | Familia de peptidos denominados xenoninas. |
FR2714908A1 (fr) * | 1994-01-11 | 1995-07-13 | Transgene Sa | Famille de peptides appelés xénoxines. |
CN1062017C (zh) * | 1995-09-01 | 2001-02-14 | 中国科学院遗传研究所 | 防御素基因的植物表达载体质粒 |
GB9724307D0 (en) * | 1997-11-17 | 1998-01-14 | Zeneca Ltd | Improvements relating to protein accumulation |
FR2777568B1 (fr) | 1998-04-15 | 2002-10-31 | Rhone Poulenc Agrochimie | Gene codant pour l'heliomicine, proteine obtenue, vecteur le contenant, organismes transformes obtenus et procede de preparation |
RU2460795C1 (ru) * | 2011-07-06 | 2012-09-10 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") | Способ микробиологического синтеза секретируемого соматотропина человека и штамм дрожжей saccharomyces cerevisiae - продуцент секретируемого соматотропина человека |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL83435A (en) * | 1986-09-23 | 1993-01-14 | Miles Lab | Dna construct for expression of genes in yeast, an expression vector containing it and yeast transformed with said expression vector |
FR2633296B1 (fr) * | 1988-06-24 | 1991-11-15 | Centre Nat Rech Scient | Molecules peptidiques a action sur les germes a gram positif |
FR2646437B1 (fr) * | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
-
1993
- 1993-01-11 FR FR9300171A patent/FR2700338B1/fr not_active Expired - Fee Related
-
1994
- 1994-01-11 DK DK94400062T patent/DK0607080T3/da active
- 1994-01-11 AT AT94400062T patent/ATE202381T1/de not_active IP Right Cessation
- 1994-01-11 EP EP94400062A patent/EP0607080B1/fr not_active Expired - Lifetime
- 1994-01-11 PT PT94400062T patent/PT607080E/pt unknown
- 1994-01-11 ES ES94400062T patent/ES2157963T3/es not_active Expired - Lifetime
- 1994-01-11 DE DE69427496T patent/DE69427496T2/de not_active Expired - Fee Related
-
2001
- 2001-09-18 GR GR20010401506T patent/GR3036648T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0607080B1 (fr) | 2001-06-20 |
ATE202381T1 (de) | 2001-07-15 |
EP0607080A1 (fr) | 1994-07-20 |
FR2700338A1 (fr) | 1994-07-13 |
PT607080E (pt) | 2001-10-31 |
DE69427496D1 (de) | 2001-07-26 |
DE69427496T2 (de) | 2002-06-06 |
FR2700338B1 (fr) | 1995-03-31 |
DK0607080T3 (da) | 2001-10-01 |
GR3036648T3 (en) | 2001-12-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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