ES2150942T3 - Metodos que permiten obtener reactivos homogeneos. - Google Patents

Metodos que permiten obtener reactivos homogeneos.

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Publication number
ES2150942T3
ES2150942T3 ES93909167T ES93909167T ES2150942T3 ES 2150942 T3 ES2150942 T3 ES 2150942T3 ES 93909167 T ES93909167 T ES 93909167T ES 93909167 T ES93909167 T ES 93909167T ES 2150942 T3 ES2150942 T3 ES 2150942T3
Authority
ES
Spain
Prior art keywords
test reagent
homogeneity
reagents
same
carousel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93909167T
Other languages
English (en)
Inventor
William J Raymoure
Frederic L Clark
Gilbert Clift
Kendall B Hendrick
William J Kanewske Iii
Peter A Lagocki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2150942T3 publication Critical patent/ES2150942T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

SE PRESENTA UN METODO PARA MODIFICAR UN REAGENTE DE ENSAYO LIQUIDO PARA SUMINISTRAR UNA HOMOGENEIDAD PROLONGADA DEL MISMO, PARTICULARMENTE CUANDO EL AGENTE DE ENSAYO LIQUIDO COMPRENDA MICROPARTICULAS PARA REALIZAR UN INMUNOENSAYO HETEROGENEO, EN EL QUE LA ADICION DE UN MATERIAL INERTE AL REAGENTE DE ENSAYO LIQUIDO CONSIGUE UNA DENSIDAD NEUTRA PARA DE ESTA FORMA PROLONGAR LA HOMOGENEIDAD DEL MISMO DURANTE PERIODOS EXTENDIDOS DE TIEMPO. TAMBIEN SE SUMINISTRA UN METODO PARA LA AGITACION AUTOMATICA DE REAGENTES DE ENSAYO PARA MANTENER LA HOMOGENEIDAD DE LOS MISMOS CON UN INSTRUMENTO ANALITICO DE ACCESO AUTOMATICO, CONTINUO Y ALEATORIO. LA MEZCLA AUTOMATICA SE REALIZA MEDIANTE UN MOVIMIENTO HACIA ATRAS Y HACIA ADELANTE DEL CARRUSEL SOBRE EL CUAL ESTAN MONTADOS LOS ENVASES DE REAGENTE DE ENSAYO CON PAUSAS ASIMETRICAS QUE PUEDAN COMPLETARSE DENTRO DE UN CORTO PERIODO DE TIEMPO. LA ACELERACION, VELOCIDAD, DISTANCIA MOVIDA Y ASIMETRIA DE PAUSAS DEL CARRUSEL SE OPTIMIZAN PARA SUMINISTRAR UNA RESUSPENSION RAPIDA DEL REAGENTE DE ENSAYO SIN FORMAR BURBUJAS. DE ACUERDO CON ELLO, LA SEPARACION PERIODICA DE LOS ENVASES DE REAGENTE DE ENSAYO EFECTUADA POR EL OPERADOR PARA MEZCLAR LOS REAGENTES NO SERA NECESARIA.
ES93909167T 1992-03-27 1993-03-24 Metodos que permiten obtener reactivos homogeneos. Expired - Lifetime ES2150942T3 (es)

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US85921892A 1992-03-27 1992-03-27
US91673792A 1992-07-20 1992-07-20

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WO (1) WO1993020444A1 (es)

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CA2129367A1 (en) 1993-10-14
EP0632894A1 (en) 1995-01-11
EP0632894B1 (en) 2000-08-23
AU3967793A (en) 1993-11-08
DE69329276D1 (de) 2000-09-28
CA2129367C (en) 2000-12-05
EP0632894A4 (en) 1997-05-02
DE69329276T2 (de) 2001-04-12
JP3003118B2 (ja) 2000-01-24
WO1993020444A1 (en) 1993-10-14
JPH07505474A (ja) 1995-06-15

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