ES2150894T1 - Vector de baculovirus modificado por proteinas de envoltura para terapia genica. - Google Patents
Vector de baculovirus modificado por proteinas de envoltura para terapia genica.Info
- Publication number
- ES2150894T1 ES2150894T1 ES98947386T ES98947386T ES2150894T1 ES 2150894 T1 ES2150894 T1 ES 2150894T1 ES 98947386 T ES98947386 T ES 98947386T ES 98947386 T ES98947386 T ES 98947386T ES 2150894 T1 ES2150894 T1 ES 2150894T1
- Authority
- ES
- Spain
- Prior art keywords
- proteins
- wrapping
- gene therapy
- baculovirus vector
- vector modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Abstract
1. Vector, que consta de un baculovirus, que contiene los siguientes componentes: - proteínas de envoltura de virus modificadas, - una secuencia heteróloga de ADN, - un promotor para la expresión en células de mamíferos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1997135593 DE19735593C2 (de) | 1997-08-15 | 1997-08-15 | Hüllprotein-modifizierter Baculovirus-Vektor für die Gentherapie |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2150894T1 true ES2150894T1 (es) | 2000-12-16 |
Family
ID=7839201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98947386T Pending ES2150894T1 (es) | 1997-08-15 | 1998-08-05 | Vector de baculovirus modificado por proteinas de envoltura para terapia genica. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1003896A1 (es) |
JP (1) | JP2003530064A (es) |
CA (1) | CA2300362A1 (es) |
DE (1) | DE19735593C2 (es) |
ES (1) | ES2150894T1 (es) |
WO (1) | WO1999009193A1 (es) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6183993B1 (en) * | 1996-09-11 | 2001-02-06 | The General Hospital Corporation | Complement-resistant non-mammalian DNA viruses and uses thereof |
GB0012997D0 (en) * | 2000-05-26 | 2000-07-19 | Eurogene Limited | Gene delivery |
US6607912B2 (en) | 2000-08-11 | 2003-08-19 | Boyce Thompson Institute For Plant Research, Inc. | GP64-null baculoviruses pseudotyped with heterologous envelope proteins |
CA2440342A1 (en) | 2001-03-12 | 2002-09-19 | Ark Therapeutics Ltd. | Avidin-pseudotyped viral vectors and their use |
EP1392837A2 (en) * | 2001-05-29 | 2004-03-03 | Ark Therapeutics Limited | Gene delivery via a baculovirus vector |
GB0119852D0 (en) | 2001-08-15 | 2001-10-10 | Univ York | Baculovirus |
US6863884B2 (en) | 2002-05-01 | 2005-03-08 | Cell Genesys, Inc. | Pseudotyped retroviral vectors |
US7416890B2 (en) | 2002-09-25 | 2008-08-26 | Osaka Industrial Promotion Organization | Baculovirus vector, method of producing thereof and method of gene transfer |
EP1548119A4 (en) * | 2002-09-25 | 2006-08-02 | Osaka Ind Promotion Org | BACULAR VIRUS VECTOR, METHOD OF CONSTRUCTING THE BACULAR VIRUS VECTOR AND GENTRANSFER METHOD |
WO2006069220A2 (en) | 2004-12-22 | 2006-06-29 | Ambrx, Inc. | Modified human growth hormone |
JP4896745B2 (ja) | 2004-02-02 | 2012-03-14 | アンブレツクス・インコーポレイテツド | 修飾されたヒトインターフェロンポリペプチドおよびこれらの使用 |
JP2008503217A (ja) | 2004-06-18 | 2008-02-07 | アンブレツクス・インコーポレイテツド | 新規抗原結合ポリペプチド及びそれらの使用 |
GB0425739D0 (en) * | 2004-11-23 | 2004-12-22 | Procure Therapeutics Ltd | Humanised baculovirus 2 |
MX2007007587A (es) | 2004-12-22 | 2007-12-11 | Ambrx Inc | Formulaciones de la hormona del crecimiento humano que comprenden un aminoacido codificado de manera no natural. |
US7638491B2 (en) | 2004-12-22 | 2009-12-29 | Ambrx, Inc. | Therapies using non-natural amino acids and polypeptides |
KR20070100299A (ko) | 2004-12-22 | 2007-10-10 | 암브룩스, 인코포레이티드 | 재조합 인간 성장 호르몬의 발현 및 정제 방법 |
WO2006068802A2 (en) | 2004-12-22 | 2006-06-29 | Ambrx, Inc. | COMPOSITIONS OF AMINOACYL-tRNA SYNTHETASE AND USES THEREOF |
WO2006133089A2 (en) | 2005-06-03 | 2006-12-14 | Ambrx, Inc. | Improved human interferon molecules and their uses |
JP2009520949A (ja) | 2005-11-16 | 2009-05-28 | アンブルックス,インコーポレイテッド | 非天然アミノ酸を含んでいる組成物および方法 |
TWI477602B (zh) | 2006-02-09 | 2015-03-21 | Educational Foundation Jichi Medical Univ | Novel viral vector |
US9333249B2 (en) | 2006-02-09 | 2016-05-10 | Educational Foundation Jichi Medical University | Recombinant baculovirus vaccine |
AU2007292892B9 (en) | 2006-09-08 | 2013-02-28 | Ambrx, Inc. | Hybrid suppressor tRNA for vertebrate cells |
AU2007292903B2 (en) | 2006-09-08 | 2012-03-29 | Ambrx, Inc. | Modified human plasma polypeptide or Fc scaffolds and their uses |
CA2682147C (en) | 2007-03-30 | 2017-08-08 | Ambrx, Inc. | Modified fgf-21 polypeptides and their uses |
NZ580686A (en) | 2007-05-02 | 2012-11-30 | Ambrx Inc | Modified interferon beta polypeptides and their uses |
CN101918026B (zh) | 2007-11-20 | 2016-03-02 | Ambrx公司 | 经修饰胰岛素多肽和其用途 |
CN101939443B (zh) | 2008-02-08 | 2014-01-29 | Ambrx公司 | 经修饰瘦素多肽和其用途 |
ES2654387T3 (es) | 2008-07-23 | 2018-02-13 | Ambrx, Inc. | Polipéptidos G-CSF bovinos modificados y sus usos |
PT2342223T (pt) | 2008-09-26 | 2017-07-07 | Lilly Co Eli | Polipéptidos de eritropoetina animal modificados e suas utilizações |
MX343802B (es) | 2008-09-26 | 2016-11-23 | Ambrx Inc | Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales. |
EA201290541A1 (ru) | 2009-12-21 | 2013-05-30 | Амбркс, Инк. | Модифицированные бычьи соматотропиновые полипептиды и их применение |
CA2784800A1 (en) | 2009-12-21 | 2011-07-21 | Ambrx, Inc. | Modified porcine somatotropin polypeptides and their uses |
MA34521B1 (fr) | 2010-08-17 | 2013-09-02 | Ambrx Inc | Polypeptides de relaxine modifiés et leurs utilisations |
US9567386B2 (en) | 2010-08-17 | 2017-02-14 | Ambrx, Inc. | Therapeutic uses of modified relaxin polypeptides |
AR083006A1 (es) | 2010-09-23 | 2013-01-23 | Lilly Co Eli | Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas |
JPWO2016059911A1 (ja) * | 2014-10-17 | 2017-07-27 | 国立大学法人金沢大学 | マラリアワクチン |
LT3412302T (lt) | 2014-10-24 | 2021-07-26 | Bristol-Myers Squibb Company | Modifikuoti fgf-21 polipeptidai ir jų panaudojimai |
SG11201907209QA (en) | 2017-02-08 | 2019-09-27 | Bristol Myers Squibb Co | Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4407859C1 (de) * | 1994-03-04 | 1995-03-02 | Max Planck Gesellschaft | Vektor für die leberspezifische Gentherapie |
WO1996009074A1 (en) * | 1994-09-23 | 1996-03-28 | The General Hospital Corporation | Use of a non-mammalian dna virus to express an exogenous gene in a mammalian cell |
US5750383A (en) * | 1996-05-14 | 1998-05-12 | Boyce Thompson Institute For Plant Research, Inc. | Baculovirus cloning system |
-
1997
- 1997-08-15 DE DE1997135593 patent/DE19735593C2/de not_active Expired - Fee Related
-
1998
- 1998-08-05 EP EP98947386A patent/EP1003896A1/de not_active Withdrawn
- 1998-08-05 WO PCT/DE1998/002255 patent/WO1999009193A1/de not_active Application Discontinuation
- 1998-08-05 CA CA002300362A patent/CA2300362A1/en not_active Abandoned
- 1998-08-05 ES ES98947386T patent/ES2150894T1/es active Pending
- 1998-08-05 JP JP2000509856A patent/JP2003530064A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1003896A1 (de) | 2000-05-31 |
DE19735593A1 (de) | 1999-02-18 |
CA2300362A1 (en) | 1999-02-25 |
DE19735593C2 (de) | 1999-08-26 |
WO1999009193A1 (de) | 1999-02-25 |
JP2003530064A (ja) | 2003-10-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2150894T1 (es) | Vector de baculovirus modificado por proteinas de envoltura para terapia genica. | |
ES2065919T3 (es) | Ribozimas. | |
AR008508A1 (es) | METODO PARA LOGRAR UNA EXPRESION ESPECíFICA MESoFILA DE UNA SECUENCIA DE NUCLEOTIDOS CODIFICANTE EN PLANTAS, CONTROLADA POR UN PROMOTOR , CASETES DE EXPRESION, VECTORES RECOMBINANTES Y MICROORGANISMOS QUE CONTIENEN DICHOS PROMOTORES, UTILIZACION DE DICHOS VECTORES Y PROMOTORES Y PROCEDIMIENTO PARA P | |
FI961146A (fi) | Adenoassosioituja virusliposomeja ja niihin liittyviä menetelmiä | |
DE69733247D1 (de) | Humanisiertes grünes-fluoreszenzprotein und methoden | |
NO981944L (no) | Lipopolyaminer som transfeksjonsmidler samt farmas÷ytisk anvendelse derav | |
ES2042693T3 (es) | Formulaciones proteinicas de plasma y recombinantes en medios de baja potencia ionica. | |
AR021139A1 (es) | Acidos nucleicos y polipeptidos de activadores de la transcripcion y metodos de uso de los mismos | |
BR9813369A (pt) | Amortecedor para uso em uma sola de sapato, e, sola de sapato. | |
CY1109367T1 (el) | Συνθεσεις και μεθοδοι για ενισχυση της παροχης θεραπευτικων παραγοντων σε κυτταρα | |
ATE270342T1 (de) | Endosomolytisch wirksame partikel | |
AR014891A1 (es) | Genes aislados de proteinas de membranas de mamiferos; reactivos relacionados | |
PT1021553E (pt) | Cassette de expressao eucariotica de genes e suas utilizacoes | |
ATE171212T1 (de) | Corticotropin freisetzende rezeptoren des faktor 2 | |
BR9800913A (pt) | Promotor de gene cdc25b, preparação e uso do mesmo. | |
AU2520595A (en) | Virosome-mediated intracellular delivery of therapeutic agents | |
PT1212428E (pt) | Redireccionamento da expressao do gene gama 34.5 de herpes atraves de um promotor especifico de celulas e/ou especifico de tumores | |
ES2165050T3 (es) | Nuevos derivados cationicos de colesterilo que contienen grupos polares ciclicos. | |
ES2179529T3 (es) | Compuestos biaromaticos unidos por un radical heteroetinileno, y composiciones farmaceuticas y cosmeticas que los contienen. | |
ES8601861A1 (es) | Un metodo de obtener un isocianato bloqueado | |
DK0986568T3 (da) | Kationiske midler til transfektion af nukleinsyrer | |
AR013853A1 (es) | Un metodo para aumentar la expresion transgenica en una poblacion de celulas de monocotiledoneas y poblacion de celulas de monocotiledoneas conexpresion transgenica aumentada. | |
ATE226638T1 (de) | Retroviraler vektor und dessen verwendung in gentherapie | |
DK0870015T3 (da) | Xylanaser, gener, der koder for disse, samt anvendelser deraf | |
DK0528925T3 (da) | Klonings- og/eller ekspressionsvektorer, deres fremstilling og anvendelse |