ES2149044T3 - Metanosulfonato de paroxetina. - Google Patents
Metanosulfonato de paroxetina.Info
- Publication number
- ES2149044T3 ES2149044T3 ES99303151T ES99303151T ES2149044T3 ES 2149044 T3 ES2149044 T3 ES 2149044T3 ES 99303151 T ES99303151 T ES 99303151T ES 99303151 T ES99303151 T ES 99303151T ES 2149044 T3 ES2149044 T3 ES 2149044T3
- Authority
- ES
- Spain
- Prior art keywords
- paroxetine
- methanosulfonate
- therapies
- procedures
- presented
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 title 1
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 title 1
- 229960002296 paroxetine Drugs 0.000 title 1
- SHIJTGJXUHTGGZ-RVXRQPKJSA-N (3s,4r)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-ium;methanesulfonate Chemical compound CS(O)(=O)=O.C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 SHIJTGJXUHTGGZ-RVXRQPKJSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Se presenta un metanosulfonato de paroxetina, procedimientos para su preparación, composiciones farmacéuticas que lo contienen y su utilización en terapias
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9814316.7A GB9814316D0 (en) | 1998-07-02 | 1998-07-02 | Novel compounds |
| GBGB9821732.6A GB9821732D0 (en) | 1998-10-06 | 1998-10-06 | Novel compound |
| GBGB9902935.7A GB9902935D0 (en) | 1999-02-10 | 1999-02-10 | Novel compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2149044T3 true ES2149044T3 (es) | 2000-10-16 |
Family
ID=27269380
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES009900849A Expired - Fee Related ES2158778B1 (es) | 1998-07-02 | 1999-04-23 | Compuestos de sales de paroxetina, su preparacion y uso, y composiciones farmaceuticas que los contienen. |
| ES99303151T Expired - Lifetime ES2149044T3 (es) | 1998-07-02 | 1999-04-23 | Metanosulfonato de paroxetina. |
| ES99918159T Expired - Lifetime ES2209428T3 (es) | 1998-07-02 | 1999-04-23 | Un solvato 1:1 de metanosulfonato de pparoxetina con acetonitrilo. |
| ES00201290T Expired - Lifetime ES2157881T3 (es) | 1998-07-02 | 2000-04-10 | Metanosulfonato de paroxetina. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES009900849A Expired - Fee Related ES2158778B1 (es) | 1998-07-02 | 1999-04-23 | Compuestos de sales de paroxetina, su preparacion y uso, y composiciones farmaceuticas que los contienen. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99918159T Expired - Lifetime ES2209428T3 (es) | 1998-07-02 | 1999-04-23 | Un solvato 1:1 de metanosulfonato de pparoxetina con acetonitrilo. |
| ES00201290T Expired - Lifetime ES2157881T3 (es) | 1998-07-02 | 2000-04-10 | Metanosulfonato de paroxetina. |
Country Status (34)
| Country | Link |
|---|---|
| US (4) | US6063927A (es) |
| EP (5) | EP1020463A1 (es) |
| JP (1) | JP2002519422A (es) |
| KR (1) | KR20010053336A (es) |
| CN (1) | CN1127502C (es) |
| AR (2) | AR011759A1 (es) |
| AT (4) | ATE195121T1 (es) |
| AU (4) | AU713877B3 (es) |
| BE (3) | BE1011664A6 (es) |
| BR (1) | BR9911682A (es) |
| CA (1) | CA2269999A1 (es) |
| CH (1) | CH689805A8 (es) |
| DE (5) | DE29907248U1 (es) |
| DK (7) | DK199900554A (es) |
| ES (4) | ES2158778B1 (es) |
| FI (2) | FI4209U1 (es) |
| FR (2) | FR2780728B1 (es) |
| GB (5) | GB2352395B (es) |
| GR (3) | GR990100140A (es) |
| HU (1) | HUP0102334A3 (es) |
| IE (5) | IES20000894A2 (es) |
| IL (1) | IL140628A (es) |
| IT (1) | IT1312540B1 (es) |
| LU (1) | LU90388B1 (es) |
| NL (4) | NL1011875C2 (es) |
| NO (1) | NO319030B1 (es) |
| NZ (1) | NZ509180A (es) |
| PL (1) | PL345214A1 (es) |
| PT (4) | PT1089996E (es) |
| SE (1) | SE9901462A0 (es) |
| SI (3) | SI1089996T1 (es) |
| SK (1) | SK20262000A3 (es) |
| TR (1) | TR200100054T2 (es) |
| WO (1) | WO2000001694A1 (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5998401A (en) * | 1995-02-28 | 1999-12-07 | Eli Lilly And Company | Naphthyl compounds, intermediates, compositions, and methods |
| BR9807625A (pt) * | 1997-02-27 | 2000-02-22 | Ajinomoto Kk | Aparelho e processo para cristalização. |
| DE69704679T2 (de) * | 1997-06-10 | 2001-09-13 | Synthon Bv | 4-phenylpiperidin-derivate |
| CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
| US20040028582A1 (en) * | 1999-03-10 | 2004-02-12 | Smithkline Beecham Corporation | Crystallization process for producing fine crystal products |
| USPP12225P2 (en) | 1999-06-01 | 2001-11-27 | Florfis Ag | Geranium plant named ‘Fislamda’ |
| ES2159260B1 (es) * | 1999-06-22 | 2002-05-01 | Smithkline Beechan Plc | Nueva composicion de metanosulfonato de paroxetina |
| AU5078700A (en) * | 1999-06-22 | 2001-01-09 | Smithkline Beecham Plc | Novel composition |
| GB0003232D0 (en) * | 2000-02-11 | 2000-04-05 | Smithkline Beecham Plc | Novel composition |
| US6306435B1 (en) | 2000-06-26 | 2001-10-23 | Yung Shin Pharmaceutical Industrial Co. Ltd. | Oral pharmaceutical preparation embedded in an oily matrix and methods of making the same |
| GB0015981D0 (en) * | 2000-06-29 | 2000-08-23 | Glaxo Group Ltd | Novel process for preparing crystalline particles |
| WO2002017921A2 (en) * | 2000-08-28 | 2002-03-07 | Synthon B.V. | Paroxetine compositions and processes for making the same |
| DE20100529U1 (de) * | 2001-01-11 | 2001-05-10 | Synthon Bv | Pharmazeutische Tablette umfassend Paroxetinmesylat |
| NL1017421C2 (nl) * | 2001-02-21 | 2002-01-15 | Synthon Bv | Werkwijze voor het vervaardigen van paroxetine. |
| WO2003020717A1 (en) * | 2001-08-02 | 2003-03-13 | Spurcourt Limited | Paroxetine isethionate salt, process of preparation and use in the treatment of depression |
| EP1490090A4 (en) | 2002-02-22 | 2006-09-20 | New River Pharmaceuticals Inc | SYSTEMS FOR DELIVERING ACTIVE AGENTS AND METHODS FOR PROTECTING AND DELIVERING ACTIVE AGENTS |
| US20050266082A1 (en) * | 2004-05-26 | 2005-12-01 | Patel Satishkumar A | Preparation of stable paroxetine HC1 ER tablets using a melt granulation process |
| WO2006018318A1 (en) * | 2004-08-18 | 2006-02-23 | Synthon B.V. | Liquid paroxetine compositions |
| US20060039975A1 (en) * | 2004-08-20 | 2006-02-23 | Zalman Vilkov | Paroxetine formulations |
| KR100672184B1 (ko) | 2004-09-21 | 2007-01-19 | 주식회사종근당 | 파록세틴의 콜린산 또는 콜린산 유도체 염 |
| EP1874908B1 (en) * | 2005-04-07 | 2014-06-11 | Xy, Llc | Method for reducing microorganisms in a flow path using diacetone alcohol |
| US20070112031A1 (en) * | 2005-11-14 | 2007-05-17 | Gant Thomas G | Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties |
| EP1966192B1 (en) * | 2005-12-01 | 2012-10-17 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
| BRPI0808354A2 (pt) * | 2007-03-09 | 2014-07-29 | Novartis Ag | Sais de 3-(1h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4 -il]-pirrola-2,5-diona |
| US8119688B2 (en) * | 2007-09-19 | 2012-02-21 | Xy, Llc | Differential evaporation potentiated disinfectant system |
| US20100249166A1 (en) * | 2007-09-19 | 2010-09-30 | Xy, Inc. | Differential evaporation potentiated disinfectant system |
| FR2926552B1 (fr) * | 2008-01-23 | 2010-03-26 | Biocodex | Procede de preparation de particules de stiripentol ayant une granulometrie definie |
| CN103961333B (zh) * | 2014-05-07 | 2020-02-21 | 浙江华海药业股份有限公司 | 甲磺酸帕罗西汀胶囊及其制备方法 |
| CN104523645A (zh) * | 2014-11-20 | 2015-04-22 | 美吉斯制药(厦门)有限公司 | 甲磺酸帕罗西汀片芯及其包衣片的制备方法 |
| US11111373B2 (en) | 2018-12-05 | 2021-09-07 | Chi Mei Corporation | Polymethacrylate composition and optical device made therefrom, and display apparatus |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE99678C (es) * | ||||
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| US4585777A (en) * | 1984-02-07 | 1986-04-29 | A/S Ferrosan | (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT |
| GB8430581D0 (en) * | 1984-12-04 | 1985-01-09 | Ferrosan As | Treatment |
| EP0190496A3 (en) * | 1984-12-13 | 1987-05-27 | Beecham Group Plc | Piperidine derivatives having a gastro-intestinal activity |
| GB8431478D0 (en) * | 1984-12-13 | 1985-01-23 | Beecham Group Plc | Compounds |
| GB8520154D0 (en) * | 1985-08-10 | 1985-09-18 | Beecham Group Plc | Chemical process |
| EP0223334B1 (en) * | 1985-08-10 | 1991-07-10 | Beecham Group Plc | Process for the preparation of aryl-piperidine carbinols |
| EP0223430B1 (en) * | 1985-10-21 | 1991-02-27 | Honda Giken Kogyo Kabushiki Kaisha | Method for controlling the solenoid current of a solenoid valve which controls the amount of suction of air in an internal combustion engine |
| DE3688827T2 (de) * | 1985-10-25 | 1994-03-31 | Beecham Group Plc | Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel. |
| IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
| GB8626936D0 (en) * | 1986-11-11 | 1986-12-10 | Ferrosan As | Treatment |
| EP0269383A3 (en) * | 1986-11-21 | 1990-05-02 | A.H. Robins Company, Incorporated | 1-Aryloxy-4-[(4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents |
| GB8714707D0 (en) * | 1987-06-23 | 1987-07-29 | Beecham Group Plc | Chemical process |
| DK716088D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Reduktion af piperidin-dion-derivater samt intermediat |
| DK715988D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Etherifikation og dealkylering af piperidin-derivater samt intermediater |
| CA2096853A1 (en) * | 1990-11-24 | 1992-05-25 | Anthony Michael Johnson | Use of paroxetine for the treatment of senile dementia, bulimia, migraine or anorexia |
| GB9209687D0 (en) * | 1992-05-06 | 1992-06-17 | Smithkline Beecham Plc | Novel process |
| US5258517A (en) * | 1992-08-06 | 1993-11-02 | Sepracor, Inc. | Method of preparing optically pure precursors of paroxetine |
| JP2773587B2 (ja) * | 1992-11-30 | 1998-07-09 | 東レ株式会社 | O,o´−ジアシル酒石酸無水物の製造法 |
| US5276042A (en) * | 1993-04-16 | 1994-01-04 | Crenshaw Roger T | Treatment of premature ejaculation |
| US5546683A (en) * | 1993-09-29 | 1996-08-20 | Clark; George J. | Bucket attachment device with remote controlled retractable pins |
| IT1274241B (it) * | 1993-12-03 | 1997-07-15 | Smithkline Beecham Farma | Complessi agente terapeutico/matrice polimerica dotati di migliorate caratteristiche di sapore e composizioni farmaceutiche che li contengono |
| GB9325644D0 (en) * | 1993-12-15 | 1994-02-16 | Smithkline Beecham Plc | Novel formulation |
| US5668134A (en) * | 1994-01-28 | 1997-09-16 | G. D. Searle & Co. | Method for preventing or reducing photosensitivity and/or phototoxicity reactions to medications |
| GB9402029D0 (en) * | 1994-02-03 | 1994-03-30 | Smithkline Beecham Plc | Novel formulation |
| CA2143070C (en) * | 1994-02-22 | 2001-12-18 | Pankaj Modi | Oral controlled release liquid suspension pharmaceutical formulation |
| EP0714663A3 (en) * | 1994-11-28 | 1997-01-15 | Lilly Co Eli | Potentiation of drug responses by serotonin 1A receptor antagonists |
| GB2297550B (en) * | 1995-02-06 | 1997-04-09 | Smithkline Beecham Plc | Paroxetine hydrochloride anhydrate substantially free of bound organic solvent |
| SK283608B6 (sk) * | 1995-02-06 | 2003-10-07 | Smithkline Beecham Plc | Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie |
| MX9707585A (es) * | 1995-04-03 | 1997-12-31 | Abbott Lab | Mezclas homogeneas de farmacos y aditivos de fusion a baja temperatura para liberacion controlada. |
| JPH11505229A (ja) * | 1995-05-17 | 1999-05-18 | ノボ ノルディスク アクティーゼルスカブ | 4−アリール−ピペリジン誘導体を製造する方法 |
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| JP3081250B2 (ja) * | 1995-10-31 | 2000-08-28 | メルク エンド カンパニー インコーポレーテッド | 置換アゼチジノンの製造方法 |
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| DE69704679T2 (de) * | 1997-06-10 | 2001-09-13 | Synthon Bv | 4-phenylpiperidin-derivate |
| CA2319652A1 (en) * | 1998-02-06 | 1999-08-12 | Michael Urquhart | Salts of paroxetine |
| SK13622000A3 (sk) * | 1998-03-16 | 2001-03-12 | Smithkline Beecham Plc | Kryštalická forma paroxetínu, farmaceutický prostriedok a použitie |
| PL343378A1 (en) * | 1998-04-09 | 2001-08-13 | Smithkline Beecham Plc | Paroxetine maleate |
| CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
| ES2159260B1 (es) * | 1999-06-22 | 2002-05-01 | Smithkline Beechan Plc | Nueva composicion de metanosulfonato de paroxetina |
| DE20100529U1 (de) * | 2001-01-11 | 2001-05-10 | Synthon Bv | Pharmazeutische Tablette umfassend Paroxetinmesylat |
-
1999
- 1999-04-20 CH CH00723/99A patent/CH689805A8/fr not_active IP Right Cessation
- 1999-04-23 IE IE20000894A patent/IES20000894A2/en not_active Application Discontinuation
- 1999-04-23 KR KR1020007015099A patent/KR20010053336A/ko not_active Withdrawn
- 1999-04-23 EP EP00201289A patent/EP1020463A1/en not_active Withdrawn
- 1999-04-23 NL NL1011875A patent/NL1011875C2/nl not_active IP Right Cessation
- 1999-04-23 EP EP99303151A patent/EP0970955B1/en not_active Revoked
- 1999-04-23 AU AU23938/99A patent/AU713877B3/en not_active Ceased
- 1999-04-23 SI SI9930482T patent/SI1089996T1/xx unknown
- 1999-04-23 PL PL99345214A patent/PL345214A1/xx not_active Application Discontinuation
- 1999-04-23 SI SI9930002T patent/SI0970955T1/xx unknown
- 1999-04-23 FR FR9905185A patent/FR2780728B1/fr not_active Expired - Fee Related
- 1999-04-23 BR BR9911682-0A patent/BR9911682A/pt not_active Application Discontinuation
- 1999-04-23 EP EP99918159A patent/EP1089996B1/en not_active Expired - Lifetime
- 1999-04-23 IE IE20000893A patent/IES20000893A2/en not_active IP Right Cessation
- 1999-04-23 HU HU0102334A patent/HUP0102334A3/hu unknown
- 1999-04-23 CN CN99810281A patent/CN1127502C/zh not_active Expired - Fee Related
- 1999-04-23 IE IE20000633A patent/IE20000633A1/en not_active IP Right Cessation
- 1999-04-23 EP EP02078483A patent/EP1288214A1/en not_active Withdrawn
- 1999-04-23 AU AU23928/99A patent/AU732211C/en not_active Ceased
- 1999-04-23 SE SE9901462A patent/SE9901462A0/sv not_active Application Discontinuation
- 1999-04-23 DE DE29907248U patent/DE29907248U1/de not_active Expired - Lifetime
- 1999-04-23 DE DE69911774T patent/DE69911774T2/de not_active Expired - Fee Related
- 1999-04-23 US US09/299,060 patent/US6063927A/en not_active Expired - Fee Related
- 1999-04-23 DK DK199900554A patent/DK199900554A/da not_active Application Discontinuation
- 1999-04-23 BE BE9900294A patent/BE1011664A6/fr not_active IP Right Cessation
- 1999-04-23 PT PT99918159T patent/PT1089996E/pt unknown
- 1999-04-23 IE IE19990344A patent/IE990344A1/en not_active IP Right Cessation
- 1999-04-23 SI SI9930009T patent/SI1020464T1/xx unknown
- 1999-04-23 NL NL1011874A patent/NL1011874C1/nl not_active IP Right Cessation
- 1999-04-23 AR ARP990101885A patent/AR011759A1/es not_active Application Discontinuation
- 1999-04-23 IT IT1999MI000866A patent/IT1312540B1/it active
- 1999-04-23 IL IL14062899A patent/IL140628A/en not_active IP Right Cessation
- 1999-04-23 JP JP2000558097A patent/JP2002519422A/ja active Pending
- 1999-04-23 GB GB0026487A patent/GB2352395B/en not_active Expired - Fee Related
- 1999-04-23 GB GB9909505A patent/GB2336364B/en not_active Revoked
- 1999-04-23 GB GB9920332A patent/GB2339428A/en not_active Withdrawn
- 1999-04-23 ES ES009900849A patent/ES2158778B1/es not_active Expired - Fee Related
- 1999-04-23 DK DK199900176U patent/DK199900176U3/da not_active IP Right Cessation
- 1999-04-23 PT PT79901275T patent/PT1020464E/pt unknown
- 1999-04-23 GB GB0119695A patent/GB2367003A/en not_active Withdrawn
- 1999-04-23 WO PCT/GB1999/001253 patent/WO2000001694A1/en not_active Ceased
- 1999-04-23 DE DE69900007T patent/DE69900007T2/de not_active Revoked
- 1999-04-23 AU AU36191/99A patent/AU3619199A/en not_active Abandoned
- 1999-04-23 CA CA002269999A patent/CA2269999A1/en not_active Abandoned
- 1999-04-23 ES ES99303151T patent/ES2149044T3/es not_active Expired - Lifetime
- 1999-04-23 AT AT99303151T patent/ATE195121T1/de not_active IP Right Cessation
- 1999-04-23 AU AU23937/99A patent/AU713131B3/en not_active Ceased
- 1999-04-23 AT AT0027999U patent/AT3185U3/de not_active IP Right Cessation
- 1999-04-23 FI FI990190U patent/FI4209U1/fi not_active IP Right Cessation
- 1999-04-23 IE IE19990343 patent/IES81166B2/en not_active IP Right Cessation
- 1999-04-23 AT AT99918159T patent/ATE251155T1/de not_active IP Right Cessation
- 1999-04-23 PT PT99303151T patent/PT970955E/pt unknown
- 1999-04-23 DE DE19918588A patent/DE19918588A1/de not_active Ceased
- 1999-04-23 GR GR990100140A patent/GR990100140A/el not_active IP Right Cessation
- 1999-04-23 PT PT102291A patent/PT102291B/pt not_active IP Right Cessation
- 1999-04-23 TR TR2001/00054T patent/TR200100054T2/xx unknown
- 1999-04-23 NZ NZ509180A patent/NZ509180A/en unknown
- 1999-04-23 FI FI990922A patent/FI112077B/fi active
- 1999-04-23 GB GB0216752A patent/GB2377637A/en not_active Withdrawn
- 1999-04-23 BE BE9900293A patent/BE1012403A5/fr not_active IP Right Cessation
- 1999-04-23 NO NO19991944A patent/NO319030B1/no unknown
- 1999-04-23 DK DK99918159T patent/DK1089996T3/da active
- 1999-04-23 DK DK99303151T patent/DK0970955T3/da active
- 1999-04-23 EP EP00201290A patent/EP1020464B1/en not_active Revoked
- 1999-04-23 ES ES99918159T patent/ES2209428T3/es not_active Expired - Lifetime
- 1999-04-23 SK SK2026-2000A patent/SK20262000A3/sk unknown
- 1999-04-23 LU LU90388A patent/LU90388B1/fr active
- 1999-04-26 AR ARP990101908A patent/AR018197A1/es unknown
- 1999-06-08 NL NL1012272A patent/NL1012272C1/nl not_active IP Right Cessation
- 1999-06-08 NL NL1012271A patent/NL1012271C2/nl not_active IP Right Cessation
- 1999-06-15 DK DK199900234U patent/DK199900234U4/da not_active IP Right Cessation
- 1999-12-23 BE BE9900832A patent/BE1012420A6/fr not_active IP Right Cessation
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2000
- 2000-04-10 AT AT00201290T patent/ATE202777T1/de not_active IP Right Cessation
- 2000-04-10 DK DK00201290T patent/DK1020464T3/da active
- 2000-04-10 DE DE60000003T patent/DE60000003T2/de not_active Revoked
- 2000-04-10 ES ES00201290T patent/ES2157881T3/es not_active Expired - Lifetime
- 2000-09-05 GR GR20000402015T patent/GR3034328T3/el not_active IP Right Cessation
- 2000-11-08 FR FR0014325A patent/FR2802098A1/fr active Pending
- 2000-12-27 DK DK200000390U patent/DK200000390U1/da not_active IP Right Cessation
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2001
- 2001-03-14 US US09/805,812 patent/US20010023253A1/en not_active Abandoned
- 2001-07-11 GR GR20010401061T patent/GR3036208T3/el not_active IP Right Cessation
- 2001-09-21 US US09/960,033 patent/US20020035130A1/en not_active Abandoned
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2002
- 2002-06-18 US US10/174,380 patent/US20020193406A1/en not_active Abandoned
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