ES2145221T3 - Procedimiento para preparar nizatidina pura. - Google Patents

Procedimiento para preparar nizatidina pura.

Info

Publication number
ES2145221T3
ES2145221T3 ES95306049T ES95306049T ES2145221T3 ES 2145221 T3 ES2145221 T3 ES 2145221T3 ES 95306049 T ES95306049 T ES 95306049T ES 95306049 T ES95306049 T ES 95306049T ES 2145221 T3 ES2145221 T3 ES 2145221T3
Authority
ES
Spain
Prior art keywords
nizatidine
procedure
preparing pure
pure
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95306049T
Other languages
English (en)
Inventor
Mary Kay Mccauley
Kenneth Philip Moder
Jeffrey Lynn Speakman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2145221T3 publication Critical patent/ES2145221T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/26—Radicals substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA UNA COMPOSICION FARMACEUTICA INOLORA DE NIZATIDINA. TAMBIEN PROPORCIONA UNA FORMA DE NIZATIDINA PURA Y UN PROCESO PARA LA PREPARACION DE LA MISMA.
ES95306049T 1994-08-30 1995-08-30 Procedimiento para preparar nizatidina pura. Expired - Lifetime ES2145221T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/298,486 US5470865A (en) 1994-08-30 1994-08-30 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
ES2145221T3 true ES2145221T3 (es) 2000-07-01

Family

ID=23150736

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95306049T Expired - Lifetime ES2145221T3 (es) 1994-08-30 1995-08-30 Procedimiento para preparar nizatidina pura.

Country Status (24)

Country Link
US (1) US5470865A (es)
EP (1) EP0704214B1 (es)
JP (1) JPH0892087A (es)
KR (1) KR960006921A (es)
CN (1) CN1127635A (es)
AT (1) ATE192039T1 (es)
AU (1) AU700488B2 (es)
BR (1) BR9503832A (es)
CA (1) CA2157240A1 (es)
CO (1) CO4410183A1 (es)
CZ (1) CZ189395A3 (es)
DE (1) DE69516475T2 (es)
ES (1) ES2145221T3 (es)
FI (1) FI954050A (es)
HU (1) HUT72672A (es)
IL (1) IL115012A0 (es)
NO (1) NO952825L (es)
NZ (1) NZ272833A (es)
PE (1) PE33696A1 (es)
PH (1) PH31452A (es)
PL (1) PL310207A1 (es)
TR (1) TR199500885A2 (es)
YU (1) YU57495A (es)
ZA (1) ZA957281B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010068707A (ko) * 2000-01-07 2001-07-23 최용준 시계줄
JP2001240534A (ja) * 2000-02-29 2001-09-04 Bio Kagaku Kk 液状組成物
KR102178793B1 (ko) * 2019-04-17 2020-11-13 황용석 순금 장식연결구

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
US4382090A (en) * 1980-10-02 1983-05-03 Eli Lilly And Company N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds
US4760075A (en) * 1980-10-02 1988-07-26 Eli Lilly And Company N-thiazolylmethylthioalkyl-N-alkyl-amidines and related compounds
US4904792A (en) * 1980-10-02 1990-02-27 Eli Lilly And Company N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds
ES8601941A1 (es) * 1983-02-07 1985-11-01 Lilly Co Eli Un procedimiento para la preparacion de nizatidina
US4587344A (en) * 1983-02-07 1986-05-06 Eli Lilly And Company Isothiourea synthesis process
US4777260A (en) * 1985-12-18 1988-10-11 Eli Lilly And Company Synthesis of nizatidine intermediate
EP0230127A1 (en) * 1985-12-18 1987-07-29 Eli Lilly And Company Synthesis of nizatidine
US4857344A (en) 1986-12-31 1989-08-15 Del Monte Corporation Method for treating pineapple to inhibit browning
EP0285681B1 (de) * 1987-04-06 1993-03-10 HEUMANN PHARMA GMBH & CO Verfahren zur Herstellung von Nitroethenderivaten
EP0396830B1 (en) * 1989-05-10 1993-10-27 Council of Scientific and Industrial Research An improved process for the preparation of 1-substituted amino-1-substituted thio-2-nitro alkenes
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
CA2055661A1 (en) * 1990-12-21 1992-06-22 Manley A. Paulos Treatment of upset stomach associated with heartburn, sour stomach or acid indigestion with an effervescent h2 blocker formulation
US5334725A (en) * 1991-05-21 1994-08-02 Eli Lilly And Company 2-aminomethyl-4-exomethylenethiazoline epoxides
US5503846A (en) * 1993-03-17 1996-04-02 Cima Labs, Inc. Base coated acid particles and effervescent formulation incorporating same

Also Published As

Publication number Publication date
CA2157240A1 (en) 1996-03-01
CN1127635A (zh) 1996-07-31
DE69516475T2 (de) 2000-09-28
KR960006921A (ko) 1996-03-22
FI954050A0 (fi) 1995-08-29
CO4410183A1 (es) 1997-01-09
BR9503832A (pt) 1996-09-10
EP0704214A1 (en) 1996-04-03
HUT72672A (en) 1996-05-28
FI954050A (fi) 1996-03-02
AU3033495A (en) 1996-03-14
ATE192039T1 (de) 2000-05-15
PH31452A (en) 1998-11-03
TR199500885A2 (tr) 1996-06-21
HU9502542D0 (en) 1995-10-30
US5470865A (en) 1995-11-28
NZ272833A (en) 1997-04-24
ZA957281B (en) 1997-02-28
PL310207A1 (en) 1996-03-04
NO952825D0 (no) 1995-07-17
PE33696A1 (es) 1996-08-29
JPH0892087A (ja) 1996-04-09
CZ189395A3 (en) 1996-03-13
NO952825L (no) 1996-03-01
DE69516475D1 (de) 2000-05-31
IL115012A0 (en) 1996-01-31
EP0704214B1 (en) 2000-04-26
YU57495A (sh) 1999-07-28
AU700488B2 (en) 1999-01-07

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