ES2144648T3 - Prevencion de la hemolisis mediante agentes tensioactivos. - Google Patents

Prevencion de la hemolisis mediante agentes tensioactivos.

Info

Publication number
ES2144648T3
ES2144648T3 ES95940391T ES95940391T ES2144648T3 ES 2144648 T3 ES2144648 T3 ES 2144648T3 ES 95940391 T ES95940391 T ES 95940391T ES 95940391 T ES95940391 T ES 95940391T ES 2144648 T3 ES2144648 T3 ES 2144648T3
Authority
ES
Spain
Prior art keywords
pct
hemolysis
prevention
emulsion
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95940391T
Other languages
English (en)
Inventor
Timothy Harrison
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Original Assignee
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd filed Critical Merck Sharp and Dohme Ltd
Application granted granted Critical
Publication of ES2144648T3 publication Critical patent/ES2144648T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE AL USO DE UN AGENTE TENSIOACTIVO NO IONICO O UNA EMULSION PARA LA REDUCCION DE LOS EFECTOS HEMOLITICOS DE UN COMPUESTO ANFIFILICO. TAMBIEN SE DESCRIBE UN METODO PARA REDUCIR LOS EFECTOS HEMOLITICOS DE UN COMPUESTO ANFIFILICO QUE INCLUYE LA FORMULACION DE DICHO COMPUESTO CON UN AGENTE TENSIOACTIVO NO IONICO O EN FORMA DE EMULSION.
ES95940391T 1994-12-23 1995-12-15 Prevencion de la hemolisis mediante agentes tensioactivos. Expired - Lifetime ES2144648T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9426104.7A GB9426104D0 (en) 1994-12-23 1994-12-23 Use of surfactants and emulsions

Publications (1)

Publication Number Publication Date
ES2144648T3 true ES2144648T3 (es) 2000-06-16

Family

ID=10766511

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95940391T Expired - Lifetime ES2144648T3 (es) 1994-12-23 1995-12-15 Prevencion de la hemolisis mediante agentes tensioactivos.

Country Status (9)

Country Link
US (1) US5880123A (es)
EP (1) EP0799026B1 (es)
JP (1) JPH10511382A (es)
AT (1) ATE191645T1 (es)
AU (1) AU714121B2 (es)
DE (1) DE69516311T2 (es)
ES (1) ES2144648T3 (es)
GB (1) GB9426104D0 (es)
WO (1) WO1996019970A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7097849B2 (en) * 1998-08-19 2006-08-29 Jagotec Ag Injectable aqueous dispersions of propofol
IN188843B (es) * 2000-06-22 2002-11-09 Vinod Daftary Gautam Dr
JP2002241311A (ja) * 2000-12-12 2002-08-28 Japan Tobacco Inc 界面活性剤を含む医薬組成物
DE10144030A1 (de) * 2001-09-07 2003-03-27 Boehringer Ingelheim Pharma Verbesserung der lokalen Verträglichkeit bei intravenöser Verabreichung von 4-(4-(2-Pyrrolylcarbonyl-1-piperazinyl)-3-trifluormethyl-benzoylguanidin
US6982256B2 (en) 2001-09-07 2006-01-03 Boehringer Ingelheim Pharma Kg Tolerance of 4-(4-(2-pyrrolylcarbonyl)-1-piperazinyl)-3-trifluoromethyl-benzoylguanidine in intravenous administration
DE102006029573A1 (de) 2006-06-22 2007-12-27 Bayer Schering Pharma Ag Neue Quinazoline als Kinase-Inhibitoren
WO2010020052A1 (en) * 2008-08-21 2010-02-25 Edouard Kouassi Methods and compounds for increasing red blood cell survival

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1202370B (it) * 1976-07-12 1989-02-09 Hoffmann La Roche Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti
JPS5919525B2 (ja) * 1976-09-03 1984-05-07 武田薬品工業株式会社 注射剤
JPS6117512A (ja) * 1984-07-03 1986-01-25 Ss Pharmaceut Co Ltd 低溶血性ビタミンｅ注射液
JPS6336826A (ja) * 1986-07-30 1988-02-17 Shiseido Co Ltd 可溶化組成物
JPH03106812A (ja) * 1989-09-16 1991-05-07 Shiseido Co Ltd 注射剤用低刺激性組成物
JPH07173079A (ja) * 1992-12-22 1995-07-11 Nippon Oil & Fats Co Ltd 両親媒性ポリエチレングリコール誘導体および用途
JP3534199B2 (ja) * 1993-11-10 2004-06-07 株式会社薬研 界面活性剤組成物
SG52217A1 (en) * 1993-12-29 1998-09-28 Merck Sharp & Dohme Substituted morpholine derivatives and their use as therapeutic agents

Also Published As

Publication number Publication date
WO1996019970A1 (en) 1996-07-04
EP0799026A1 (en) 1997-10-08
US5880123A (en) 1999-03-09
DE69516311T2 (de) 2000-11-09
AU4185996A (en) 1996-07-19
ATE191645T1 (de) 2000-04-15
AU714121B2 (en) 1999-12-16
GB9426104D0 (en) 1995-02-22
JPH10511382A (ja) 1998-11-04
EP0799026B1 (en) 2000-04-12
DE69516311D1 (de) 2000-05-18

Similar Documents

Publication Publication Date Title
BR9406823A (pt) Aminas secundárias e agentes anti-diabéticos e antiobesidade
PL320064A1 (en) Application of dioxomorpholines for fighting against endoparasites, novel dioxomorphoines and method of obtaining them
SE9101709D0 (sv) Lipidderivat som diagnostikum eller kontrastmedel
BR9612661A (pt) Utilização de uma combinaç i de tensoatives agentes quelantes e óleos essenciais para desinfecção eficaz
HUT74474A (en) Pharmaceutical emulsion comprising a short acting dihydropyridine type antihypertensive agent
ES2136723T3 (es) Utilizacion de n-aril-metilen-etilen-diamino-triacetatos, n-aril-metilen-imino-diacetatos o n,n'-diaril-metilen-etilen-diamino-acetatos contra el estres oxidante.
DK0584136T3 (da) Bestemmelse af peptidmotiver på MHC-molekyler
DK0690868T3 (da) Alkylglucosid og anvendelse deraf
FR2720934B1 (fr) Emulsion nettoyante huile-dans-eau ayant l'aspect d'un lait.
DK0900077T3 (da) Anvendelse af en toremifene-metabolit til sænkning af serumcholesterolspejlet
ES2144648T3 (es) Prevencion de la hemolisis mediante agentes tensioactivos.
ES2172600T3 (es) Composicion farmaceutica que comprende lamotrigina.
DE69302677D1 (de) Liposomale piroxycam formulierung
FR2742048B1 (fr) Utilisation de l'alpha-cyano-beta, beta-diphenylacrylate de 2-ethylhexyle pour ameliorer la stabilite de compositions cosmetiques contenant le p-methyl-benzylidene camphre en association avec un derive de dibenzoylmethane
LV10839A (lv) Arstniecibas lidzeklis lipidu un holesterina vielmainas traucejumu profilaksei un arstesanai so traucejumu profilakses un arstesanas panemiens
DE60012068D1 (de) Zusammensetzung mit kontinuierlicher wässeriger Phase, die L-2-Oxothiazolidin- 4-carbonsäure enthält".
DE69319589D1 (de) Juckreizstillendes mittel
ES2121338T3 (es) Emulsiones de aceite en agua.
PT828486E (pt) Utilizacao de derivados de pirrolidina no tratamento do alcoolismo
CA2207652A1 (en) Hemolysis prevention by surfactants and emulsions
GB9507883D0 (en) Compounds
ATE224720T1 (de) Geliertes hyperkalorisches laxierendmittel enthaltend flüssiges paraffinöl und lactulose, und verfahren
ATE208204T1 (de) Flüssigkeitsersatzlösung
SE9500983D0 (sv) Alkaliskt rengöringsmedel, med höga halter av nonjonisk tensid och komplexbildare samt användning av en amfotär som solubiliserande medel

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 799026

Country of ref document: ES