ES2139602T3 - Composiciones oculares que contienen esteroides y su utilizacion para el tratamiento del glaucoma. - Google Patents

Composiciones oculares que contienen esteroides y su utilizacion para el tratamiento del glaucoma.

Info

Publication number
ES2139602T3
ES2139602T3 ES92912769T ES92912769T ES2139602T3 ES 2139602 T3 ES2139602 T3 ES 2139602T3 ES 92912769 T ES92912769 T ES 92912769T ES 92912769 T ES92912769 T ES 92912769T ES 2139602 T3 ES2139602 T3 ES 2139602T3
Authority
ES
Spain
Prior art keywords
pct
glaucoma
treatment
date
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92912769T
Other languages
English (en)
Inventor
Gerard Schwadrohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Theramex SAM
Original Assignee
Laboratoire Theramex SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9109017A external-priority patent/FR2679139B1/fr
Priority claimed from FR9109015A external-priority patent/FR2679137B1/fr
Priority claimed from FR9109016A external-priority patent/FR2679138B1/fr
Priority claimed from FR9110160A external-priority patent/FR2680108B1/fr
Application filed by Laboratoire Theramex SAM filed Critical Laboratoire Theramex SAM
Application granted granted Critical
Publication of ES2139602T3 publication Critical patent/ES2139602T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA INVENCION SE REFIERE AL DOMINIO DE LA QUIMICA TERAPEUTICA. CONCIERNE MAS EN PARTICULAR AL DE LA REALIZACION DE COMPOSICIONES FARMACEUTICAS PARA LA APLICACION OCULAR. TIENE POR OBJETO UNAS COMPOSICIONES FARMACEUTICAS PARA LA APLICACION OCULAR CARACTERIZADAS EN QUE ENCIERRAN AL MENOS UN COMPUESTO DE ESTRUCTURA ESTEROIDIANA SELECCIONADA EN ASOCIACION O EN MEZCLA CON UN EXCIPIENTE O UN VEHICULO INERTE FARMACEUTICAMENTE ACEPTABLE. LAS COMPOSICIONES SEGUN LA INVENCION ESTAN DIRIGIDAS PARA EL TRATAMIENTO DE LA GLAUCOMA.
ES92912769T 1991-06-18 1992-06-18 Composiciones oculares que contienen esteroides y su utilizacion para el tratamiento del glaucoma. Expired - Lifetime ES2139602T3 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
FR9107412 1991-06-18
FR9109017A FR2679139B1 (fr) 1991-07-17 1991-07-17 Nouvelles compositions pharmaceutiques destinees a l'application oculaire renfermant un derive androstenique et leur procede de preparation.
FR9109015A FR2679137B1 (fr) 1991-07-17 1991-07-17 Nouvelles compositions pharmaceutiques a base d'un derive pregnenique et leur procede de preparation.
FR9109016A FR2679138B1 (fr) 1991-07-17 1991-07-17 Compositions pharmaceutiques anti-glaucomateuses et leur procede d'obtention.
FR9110160A FR2680108B1 (fr) 1991-08-09 1991-08-09 Nouvelles compositions pharmaceutiques a base de sterouides 6-hydroxymethyles et leur procede d'obtention.
PCT/FR1992/000549 WO1992022300A1 (fr) 1991-06-18 1992-06-18 Compositions oculaires contenant des steroïdes et leur utilisation pour le traitement du glaucome

Publications (1)

Publication Number Publication Date
ES2139602T3 true ES2139602T3 (es) 2000-02-16

Family

ID=27515565

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92912769T Expired - Lifetime ES2139602T3 (es) 1991-06-18 1992-06-18 Composiciones oculares que contienen esteroides y su utilizacion para el tratamiento del glaucoma.

Country Status (11)

Country Link
US (1) US5506220A (es)
EP (1) EP0593520B1 (es)
JP (1) JP3328729B2 (es)
KR (1) KR100249555B1 (es)
AT (1) ATE185071T1 (es)
CA (1) CA2111699A1 (es)
DE (1) DE69230069T2 (es)
DK (1) DK0593520T3 (es)
ES (1) ES2139602T3 (es)
GR (1) GR3031967T3 (es)
WO (1) WO1992022300A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004093882A1 (ja) * 2003-04-18 2004-11-04 Advanced Medicine Research Institute 眼に適用する疾患治療剤
CA2527175A1 (en) * 2003-04-18 2004-10-28 Advanced Medicine Research Institute Remedies for diseases to be applied to eye
PT1919290E (pt) * 2005-07-12 2014-03-20 Ampio Pharmaceuticals Inc Métodos e produtos para tratamento de doenças
WO2010151531A1 (en) * 2009-06-22 2010-12-29 Dmi Acquistion Corp. Methods and products for treatment of diseases
DE202010017530U1 (de) 2009-06-22 2012-03-28 Dmi Acquisition Corp. Danazolverbindung zur Behandlung von Krankheiten
CN102134265B (zh) * 2009-12-29 2013-04-03 黄云生 一种合成6-甲基-17α-乙酰氧基-19-去甲孕甾-4,6-二烯-3,20-二酮的方法
NZ618019A (en) 2011-05-20 2015-03-27 Inserm Inst Nat De La Santé Et De La Rech Médicale Antagonists of cb1 receptor.
CN105189529B (zh) 2012-11-28 2017-09-05 国家医疗保健研究所 孕烯醇酮的3‑(4’‑取代的)‑苄基‑醚衍生物
SG10201705044YA (en) 2012-12-19 2017-07-28 Ampio Pharmaceuticals Inc Method for treatment of diseases

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1515284A (en) * 1974-05-21 1978-06-21 Gastaud J Pharmaceutical compositions containing progestogens derived from the 17-alpha-hydroxy-19-nor-progesterone series
US4383992A (en) * 1982-02-08 1983-05-17 Lipari John M Water-soluble steroid compounds
US4617299A (en) * 1983-12-19 1986-10-14 Knepper Paul A Method for the prevention of ocular hypertension, treatment of glaucoma and treatment of ocular hypertension
US4863912A (en) * 1986-05-19 1989-09-05 New York Medical College Use of tetrahydrocortisol in glaucoma therapy
WO1987007141A1 (en) * 1986-05-23 1987-12-03 New England Medical Center Hospitals, Inc. Method for treating glaucoma
FR2622194B1 (fr) * 1987-10-27 1990-03-23 Theramex Laboratoire Nouveaux derives de la 19-nor progesterone, leur procede d'obtention et les compositions pharmaceutiques en contenant
US4876250A (en) * 1988-10-31 1989-10-24 Alcon Laboratories, Inc. Methods for controlling ocular hypertension with angiostatic steroids
FR2645864B1 (fr) * 1989-04-13 1991-07-12 Theramex Nouveaux derives alcoyles en 17/21 de la 19-nor progesterone, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
FR2679236B1 (fr) 1991-07-18 1997-01-24 Theramex Nouveaux sterouides substitues en position 6, leurs procedes d'obtention et des compositions pharmaceutiques en renfermant.

Also Published As

Publication number Publication date
KR100249555B1 (ko) 2000-04-01
CA2111699A1 (fr) 1992-12-23
KR940701260A (ko) 1994-05-28
JP3328729B2 (ja) 2002-09-30
ATE185071T1 (de) 1999-10-15
JPH06508362A (ja) 1994-09-22
WO1992022300A1 (fr) 1992-12-23
GR3031967T3 (en) 2000-03-31
US5506220A (en) 1996-04-09
EP0593520A1 (fr) 1994-04-27
DE69230069T2 (de) 2000-05-25
DK0593520T3 (da) 2000-04-03
EP0593520B1 (fr) 1999-09-29
DE69230069D1 (de) 1999-11-04

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