ES2139363T3 - Nuevos peptidos para uso en el tratamiento de la destruccion del cartilago mediada por celulas t en enfermedades autoinmunes. - Google Patents

Nuevos peptidos para uso en el tratamiento de la destruccion del cartilago mediada por celulas t en enfermedades autoinmunes.

Info

Publication number
ES2139363T3
ES2139363T3 ES96920822T ES96920822T ES2139363T3 ES 2139363 T3 ES2139363 T3 ES 2139363T3 ES 96920822 T ES96920822 T ES 96920822T ES 96920822 T ES96920822 T ES 96920822T ES 2139363 T3 ES2139363 T3 ES 2139363T3
Authority
ES
Spain
Prior art keywords
treatment
cartilage
cells
peptides
autoimmune diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96920822T
Other languages
English (en)
Inventor
Gijsbertus Francisc Verheijden
Anna Maria Helena Boots
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Application granted granted Critical
Publication of ES2139363T3 publication Critical patent/ES2139363T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725—Proteoglycans, e.g. aggreccan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

LA INVENCION ESTA RELACIONADA CON EL EMPLEO DE NUEVOS PEPTIDOS EN UN TRATAMIENTO DE TOLERANCIA INDUCIDA POR PEPTIDOS, PARA LA INDUCCION DE TOLERANCIA A LAS CELULAS T AUTOAGRESIVAS ASOCIADAS A LA DESTRUCCION DE CARTILAGO ARTICULAR MEDIADA POR CELULAS T EN ENFERMEDADES AUTOINMUNES, ESPECIFICAMENTE LA ARTRITIS. LA INVENCION TAMBIEN ABARCA COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN LOS PEPTIDOS CITADOS Y UN METODO DIAGNOSTICO PARA LA DETECCION DE CELULAS T AUTORREACTIVAS EN UNA MUESTRA PROBLEMA, LAS CELULAS T CITADAS QUE SE ASOCIAN A LA DESTRUCCION DE CARTILAGO ARTICULAR MEDIADA POR CELULAS T EN ENFERMEDADES AUTOINMUNES Y EQUIPOS DE ANALISIS PARA UTILIZAR EN EL METODO CITADO.
ES96920822T 1995-06-19 1996-06-17 Nuevos peptidos para uso en el tratamiento de la destruccion del cartilago mediada por celulas t en enfermedades autoinmunes. Expired - Lifetime ES2139363T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95201656 1995-06-19

Publications (1)

Publication Number Publication Date
ES2139363T3 true ES2139363T3 (es) 2000-02-01

Family

ID=8220392

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96920822T Expired - Lifetime ES2139363T3 (es) 1995-06-19 1996-06-17 Nuevos peptidos para uso en el tratamiento de la destruccion del cartilago mediada por celulas t en enfermedades autoinmunes.

Country Status (21)

Country Link
EP (1) EP0833842B1 (es)
JP (1) JPH11507919A (es)
KR (1) KR19990022972A (es)
CN (1) CN1155617C (es)
AT (1) ATE185151T1 (es)
AU (1) AU704942B2 (es)
BR (1) BR9608626A (es)
CA (1) CA2221981A1 (es)
DE (1) DE69604492T2 (es)
DK (1) DK0833842T3 (es)
ES (1) ES2139363T3 (es)
GR (1) GR3031990T3 (es)
HU (1) HU223275B1 (es)
IL (1) IL118524A (es)
MX (1) MX9710508A (es)
NO (1) NO975968L (es)
NZ (1) NZ311022A (es)
PL (1) PL185258B1 (es)
TR (1) TR199701658T1 (es)
WO (1) WO1997000270A1 (es)
ZA (1) ZA965163B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
DK2319928T3 (da) 1998-10-23 2013-06-24 Kirin Amgen Inc Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
IL132611A0 (en) 1999-10-27 2001-03-19 Yeda Res & Dev Synthetic genes and polypeptides and pharmaceutical compositions comprising them
US7572631B2 (en) 2000-02-24 2009-08-11 Invitrogen Corporation Activation and expansion of T cells
US7541184B2 (en) 2000-02-24 2009-06-02 Invitrogen Corporation Activation and expansion of cells
US20050084967A1 (en) 2002-06-28 2005-04-21 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
ES2629397T3 (es) 2004-09-24 2017-08-09 Amgen Inc. Moléculas de Fc modificadas
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
WO2020112906A1 (en) * 2018-11-26 2020-06-04 North Carolina State University Peptide ligands for capture of host cell proteiins

Also Published As

Publication number Publication date
ZA965163B (en) 1997-01-23
HUP9802197A2 (hu) 1999-02-01
NZ311022A (en) 1999-11-29
TR199701658T1 (xx) 1998-06-22
EP0833842A1 (en) 1998-04-08
MX9710508A (es) 1998-03-31
CN1188483A (zh) 1998-07-22
BR9608626A (pt) 1999-06-15
IL118524A0 (en) 1996-09-12
PL324208A1 (en) 1998-05-11
DE69604492T2 (de) 2000-04-13
HU223275B1 (hu) 2004-04-28
NO975968D0 (no) 1997-12-18
CA2221981A1 (en) 1997-01-03
IL118524A (en) 2004-02-19
JPH11507919A (ja) 1999-07-13
DK0833842T3 (da) 2000-04-03
DE69604492D1 (de) 1999-11-04
PL185258B1 (pl) 2003-04-30
AU704942B2 (en) 1999-05-06
WO1997000270A1 (en) 1997-01-03
HUP9802197A3 (en) 1999-06-28
GR3031990T3 (en) 2000-03-31
EP0833842B1 (en) 1999-09-29
CN1155617C (zh) 2004-06-30
ATE185151T1 (de) 1999-10-15
KR19990022972A (ko) 1999-03-25
AU6224696A (en) 1997-01-15
NO975968L (no) 1997-12-18

Similar Documents

Publication Publication Date Title
ES2139363T3 (es) Nuevos peptidos para uso en el tratamiento de la destruccion del cartilago mediada por celulas t en enfermedades autoinmunes.
ES2122231T3 (es) Inmunoanalisis para la deteccion de colageno tipo i o fragmentos de colageno correspondientes.
MX9203379A (es) Proteinas producidas por los linfocitos humanos, secuencia de adn que codifica para estas proteinas y composiciones farmaceuticas que las contienen.
ES2139017T3 (es) Compuestos que inhiben la replicacion del vih.
IT1136689B (it) Procedimento per trasformare in concime materiale macerato da rifiuti organici e,oppure da fango di chiarificazione in due stadi di procedimento
ES2090140T3 (es) Peptidos terapeuticos.
ES2122964T3 (es) Sitio de union de icam-1 para mac-1.
ES2142569T3 (es) Procedimientos y compuestos para la deteccion magneto-relaxometrica de analitos y su utilizacion.
DK187089D0 (da) Steril beholder til opsamling af biologiske proever til brug ved analyser
DE69637844D1 (de) Neues tgf-beta-ahnliches cytokin
HUP9901375A2 (hu) Antigénspecifikus immunszupressziós génterápiában alkalmazható új peptidek
ES2119747T3 (es) Metodo para la preparacion y purificacion de una mezcla de glicosfingolipidos libre de contaminacion por virus no convencionales.
ES2151544T3 (es) Metodos para la deteccion y el tratamiento de individuos con celulas anormales que expresan antigenos peptidos hla-a2/tirosinasa.
AR004093A1 (es) El uso de una proteina derivada de una quimioquina de mamifero y un medicamento util para movilizar celulas tronco hematopoyeticas.
ES2144626T3 (es) Uso de peptidos de adhesion celular para la modificacion del poder de adhesion de celulas eucarioticas entre si.
MX9706437A (es) Proceso y compuestos para la deteccion de analitos usando medicion de remanencia y el uso de los mismos.
TR200100175T2 (tr) Otoimmün hastalıkların immünoterapisinde kullanılmak üzere yeni peptitler.
MX9400799A (es) Dispositivo para la recoleccion de sangre.
ES2175069T3 (es) Deteccion de anticuerpos anti-dna que implica el reconocimiento y la union de secuencias telomericas de dna.
ECSP993062A (es) Nuevos peptidos para ser usados en una terapia de tolerancia inducida para impedir las alteraciones autoinmunes, en particular, artritis reumatoidea
ES2173180T3 (es) Derivados del mercaptoacetilamida hipocolesterolemicos, antiateroescleroticos e hipotrigliceridemicos.
ES2193601T3 (es) Utilizacion de peptidos de citrulina derivados a la filagrina en el marco del tratamiento de enfermedades autoinmunes.
AR016052A1 (es) Un metodo para diferenciar entre las variantes 2a y 2b de interferon alfa
ES2150034T3 (es) Empleo de las 2-aminotetralinas substituidas en 6,7 para la preparacion de composiciones farmaceuticas de utilidad para el tratamiento del choque septico, y composiciones farmaceuticas antipireticas y antiinflamatorias.
ES2156173T3 (es) Metodo de obtencion de paginas de teletexto.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 833842

Country of ref document: ES