BR0114977A - segmentos preferidos de proteìna de filamento neural e métodos para uso dos mesmos - Google Patents

segmentos preferidos de proteìna de filamento neural e métodos para uso dos mesmos

Info

Publication number
BR0114977A
BR0114977A BRPI0114977-6A BR0114977A BR0114977A BR 0114977 A BR0114977 A BR 0114977A BR 0114977 A BR0114977 A BR 0114977A BR 0114977 A BR0114977 A BR 0114977A
Authority
BR
Brazil
Prior art keywords
methods
preferred
filament protein
neural
preferred segments
Prior art date
Application number
BRPI0114977-6A
Other languages
English (en)
Inventor
Judith Fitzpatrick
Paul Averback
Ma Soledad S Focht
Riza Bibiano
Original Assignee
Nymox Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nymox Pharmaceuticals Corp filed Critical Nymox Pharmaceuticals Corp
Publication of BR0114977A publication Critical patent/BR0114977A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"SEGMENTOS PREFERIDOS DE PROTEìNA DE FILAMENTO NEURAL E MéTODOS PARA USO DOS MESMOS". A invenção é dirigida a seqüências de repetição preferidas de Proteína de Filamento Neural (NTP), peptídeos, miméticos, anticorpos, e ácidos nucléicos das seqüências preferidas, e métodos diagnósticos e terapêuticos para o uso de tais seqüências preferidas de NTP.
BRPI0114977-6A 2000-10-27 2001-10-25 segmentos preferidos de proteìna de filamento neural e métodos para uso dos mesmos BR0114977A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/697,590 US7259232B1 (en) 2000-10-27 2000-10-27 Preferred segments of neural thread protein
PCT/US2001/042813 WO2002034915A2 (en) 2000-10-27 2001-10-25 Preferred segments of neural thread protein and methods of using the same

Publications (1)

Publication Number Publication Date
BR0114977A true BR0114977A (pt) 2006-05-09

Family

ID=24801714

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0114977-6A BR0114977A (pt) 2000-10-27 2001-10-25 segmentos preferidos de proteìna de filamento neural e métodos para uso dos mesmos

Country Status (15)

Country Link
US (2) US7259232B1 (pt)
EP (2) EP1702985A3 (pt)
JP (1) JP2005512500A (pt)
KR (1) KR100843792B1 (pt)
CN (1) CN1492926A (pt)
AT (1) ATE330011T1 (pt)
AU (1) AU2002232392A1 (pt)
BR (1) BR0114977A (pt)
CA (1) CA2427070A1 (pt)
CY (1) CY1105380T1 (pt)
DE (1) DE60120782T2 (pt)
DK (1) DK1379650T3 (pt)
ES (1) ES2266296T3 (pt)
PT (1) PT1379650E (pt)
WO (1) WO2002034915A2 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002302239B2 (en) * 2000-10-27 2006-12-14 Nymox Corporation Method of preventing cell death using segments of neural thread proteins
EP1541166B1 (en) * 2001-05-16 2007-12-19 Nymox Corporation Preventing cell death using segments of neural thread proteins
DK1392347T3 (da) 2001-05-16 2005-12-12 Nymox Corp Fremgangsmåde til at forhindre celledöd med anvendelse af segmenter af neurale trådproteiner
NZ529911A (en) * 2001-05-25 2008-05-30 Nymox Corp Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells
US7544771B2 (en) * 2005-02-23 2009-06-09 Nymox Corporation Protein and its use in diagnosing Alzheimer's disease
US11628202B2 (en) 2015-07-24 2023-04-18 Nymox Corporation Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia
US10183058B2 (en) * 2016-06-17 2019-01-22 Nymox Corporation Method of preventing or reducing the progression of prostate cancer
US10172910B2 (en) 2016-07-28 2019-01-08 Nymox Corporation Method of preventing or reducing the incidence of acute urinary retention
US10532081B2 (en) 2016-09-07 2020-01-14 Nymox Corporation Method of ameliorating or preventing the worsening or the progression of symptoms of BPH
US10335453B2 (en) 2017-03-01 2019-07-02 Nymox Corporation Compositions and methods for improving sexual function

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068375A3 (en) 1981-06-22 1983-04-13 G.D. Searle & Co. Recombinant dna techniques for the production of relaxin
SE8300693L (sv) 1983-02-09 1984-08-10 Sven Lofdahl Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5084559A (en) 1987-03-27 1992-01-28 Repligen Corporation Protein a domain mutants
US5948634A (en) 1988-12-21 1999-09-07 The General Hospital Coporation Neural thread protein gene expression and detection of alzheimer's disease
ATE145285T1 (de) 1988-12-21 1996-11-15 Gen Hospital Corp Nachweis einer neurologischen krankheit oder einer funktionsstörung
DE69532485T2 (de) * 1994-03-07 2004-11-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung
GB9422175D0 (en) 1994-11-03 1994-12-21 Univ Dundee Indentification of the p21 waf1-pcna interaction site and therapeutic applications thereof
US5958416A (en) 1994-12-16 1999-09-28 Regents Of The University Of Minnesota Heat shock protein peptides and methods for modulating autoimmune central nervous system disease
US6610506B1 (en) * 1995-12-01 2003-08-26 University Technologies International, Inc. Transferrin binding proteins of Pasteurella haemolytica and vaccines containing same
US6013763A (en) 1996-06-04 2000-01-11 Genentech, Inc. Peptide variants of protein A
AU1065099A (en) 1997-09-30 1999-04-23 Cel-Sci Corporation Immunogenic conjugated polypeptide for treatment of herpes simplex virus
AU4859399A (en) 1998-07-02 2000-01-24 President And Fellows Of Harvard College Compositions and methods for treating papillomavirus-infected cells
EP1161446A1 (en) 1999-03-12 2001-12-12 Human Genome Sciences, Inc. 50 human secreted proteins
EP1165827A4 (en) 1999-03-26 2003-05-02 Human Genome Sciences Inc 45 HUMAN SECRETED PROTEINS
DK1392347T3 (da) 2001-05-16 2005-12-12 Nymox Corp Fremgangsmåde til at forhindre celledöd med anvendelse af segmenter af neurale trådproteiner

Also Published As

Publication number Publication date
WO2002034915A2 (en) 2002-05-02
EP1379650B1 (en) 2006-06-14
ES2266296T3 (es) 2007-03-01
JP2005512500A (ja) 2005-05-12
EP1702985A3 (en) 2007-03-07
DE60120782D1 (de) 2006-07-27
EP1379650A2 (en) 2004-01-14
PT1379650E (pt) 2006-10-31
KR20030067681A (ko) 2003-08-14
AU2002232392A1 (en) 2002-05-06
DE60120782T2 (de) 2007-05-24
DK1379650T3 (da) 2006-10-23
ATE330011T1 (de) 2006-07-15
EP1702985A2 (en) 2006-09-20
CA2427070A1 (en) 2002-05-02
KR100843792B1 (ko) 2008-07-03
CN1492926A (zh) 2004-04-28
WO2002034915A3 (en) 2003-11-20
US20090258426A1 (en) 2009-10-15
US7259232B1 (en) 2007-08-21
CY1105380T1 (el) 2010-04-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2112 DE 28/06/2011.