ES2122231T3 - Inmunoanalisis para la deteccion de colageno tipo i o fragmentos de colageno correspondientes. - Google Patents

Inmunoanalisis para la deteccion de colageno tipo i o fragmentos de colageno correspondientes.

Info

Publication number
ES2122231T3
ES2122231T3 ES94905104T ES94905104T ES2122231T3 ES 2122231 T3 ES2122231 T3 ES 2122231T3 ES 94905104 T ES94905104 T ES 94905104T ES 94905104 T ES94905104 T ES 94905104T ES 2122231 T3 ES2122231 T3 ES 2122231T3
Authority
ES
Spain
Prior art keywords
collagen
detection
type
fragments
immuno analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94905104T
Other languages
English (en)
Inventor
Werner Naser
Erasmus Huber
Christoph Seidel
Ulrich Essig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1993/002010 external-priority patent/WO1994003813A1/de
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2122231T3 publication Critical patent/ES2122231T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA INVENCION SE REFIERE A INMUNOASAI PARA LA DETECCION DE COLAGENO O FRAGMENTOS DE COLAGENO EN UNA MUESTRA BAJO UTILIZACION DE UN ANTICUERPO, QUE RECONOCE UN PEPTIDO LINEAL SINTETICO, QUE CORRESPONDE A UNA SECUENCIA DE LAS SECUENCIAS C - O N TERMINALES NO HELICOIDALES DEL COLAGENO, DONDE CON PREFERENCIA SE DESNATURALIZA LA MUESTRA.
ES94905104T 1993-07-28 1994-01-21 Inmunoanalisis para la deteccion de colageno tipo i o fragmentos de colageno correspondientes. Expired - Lifetime ES2122231T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1993/002010 WO1994003813A1 (de) 1992-07-29 1993-07-28 Immunoassay zum nachweis von kollagen oder kollagenfragmenten

Publications (1)

Publication Number Publication Date
ES2122231T3 true ES2122231T3 (es) 1998-12-16

Family

ID=8165750

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94905104T Expired - Lifetime ES2122231T3 (es) 1993-07-28 1994-01-21 Inmunoanalisis para la deteccion de colageno tipo i o fragmentos de colageno correspondientes.

Country Status (9)

Country Link
EP (1) EP0711415B1 (es)
JP (1) JP2703116B2 (es)
AT (1) ATE168779T1 (es)
CA (1) CA2167496A1 (es)
DE (1) DE59406512D1 (es)
DK (1) DK0711415T3 (es)
ES (1) ES2122231T3 (es)
FI (1) FI960392A0 (es)
WO (1) WO1995004282A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6110689A (en) * 1994-01-21 2000-08-29 Osteometer A/S Method of assaying collagen fragments in body fluids, a test kit and means for carrying out the method and use of the method to diagnose the presence of disorders associated with the metabolism of collagen
GB9506050D0 (en) 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
EP0787301B1 (en) 1994-10-17 2001-02-14 Osteometer Biotech AS Estimation of the fragmentation pattern of collagen in body fluids and the diagnosis of disorders associated with the metabolism of collagen
US5750647A (en) * 1995-05-19 1998-05-12 Washington Research Foundation Synthetic peptide analogs of NTx
US6107047A (en) * 1996-03-21 2000-08-22 Osteometer Biotech A/S Assaying protein fragments in body fluids
GB9617616D0 (en) 1996-08-22 1996-10-02 Osteometer Biotech As Assaying protein fragments in body fluids
WO1998026286A2 (en) 1996-12-09 1998-06-18 Osteometer Biotech A/S Sandwich assays for collagen type i fragments
US6117646A (en) * 1997-09-22 2000-09-12 Osteometer Biotech A/S Assaying protein fragments in body fluids
US6916903B2 (en) 1998-06-19 2005-07-12 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
US6348320B1 (en) 1998-06-19 2002-02-19 Washington Research Foundation Cartilage resorption assays measuring type II collagen fragments
US6602980B1 (en) 1998-06-19 2003-08-05 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
DE19980834T1 (de) 1998-06-19 2001-06-13 Washington Res Found Knorpel-Resorptionstests
PT1149111E (pt) * 1999-01-06 2009-11-19 Univ Southern California Processo e composição para a inibição da angiogénese
DE60042487D1 (de) 1999-07-13 2009-08-13 Univ Southern California Methode und zusammensetzung zur angiogenese-inhibierung mit antagonisten gegen mmp-9 und beta1-integrine
US7390885B2 (en) 2001-11-26 2008-06-24 Cell Matrix, Inc. Humanized collagen antibodies and related methods
US7365167B2 (en) 2001-11-26 2008-04-29 Cell Matrix, Inc. Humanized collagen antibodies and related methods
US7488792B2 (en) 2002-08-28 2009-02-10 Burnham Institute For Medical Research Collagen-binding molecules that selectively home to tumor vasculature and methods of using same
JP2004108914A (ja) * 2002-09-18 2004-04-08 Kudo Norio コラーゲンの測定方法
US7781171B2 (en) 2003-10-15 2010-08-24 Daiichi Pure Chemicals Co., Ltd. Mehod of pretreating sample and immunological assay method using the same
WO2005038458A1 (ja) * 2003-10-15 2005-04-28 Daiichi Pure Chemicals Co., Ltd. 試料の前処理方法及びこれを利用する免疫学的測定方法
WO2022202876A1 (ja) 2021-03-24 2022-09-29 積水メディカル株式会社 Ｉ型コラーゲンｃ末端テロペプチドの免疫学的分析方法
WO2024034580A1 (ja) * 2022-08-08 2024-02-15 株式会社先端生命科学研究所 Ｃｅａｃａｍ１を検出する方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0121303B1 (en) * 1983-03-04 1989-07-26 Noctech Limited Diagnostic agent, a process for its preparation and its use in diagnostic methods
CA1339952C (en) * 1984-10-29 1998-07-14 William J. Knowles Immunoassays for denatured protein analytes, particularly hb alc, and monoclonal antibodies thereto
DE3714634A1 (de) * 1987-05-02 1988-11-17 Hoechst Ag Verfahren zur selektiven immunologischen bestimmung von intaktem prokollagen peptid (typ iii) und prokollagen (typ iii) in koerperfluessigkeiten und mittel zu dessen durchfuehrung
DE58908787D1 (de) * 1988-04-27 1995-02-02 Hoechst Ag Monoklonaler Antikörper zur selektiven immunologischen Bestimmung von intaktem Prokollagen Peptid (Typ III) und Prokollagen (Typ III) in Körperflüssigkeiten.
WO1990008195A1 (en) * 1989-01-13 1990-07-26 President And Fellows Of Harvard College Monoclonal antibody to human type ix collagen
US5081031A (en) * 1989-12-14 1992-01-14 Regents Of The University Of Minnesota Synthetic polypeptide with type iv collagen activity
GB9014220D0 (en) * 1990-06-26 1990-08-15 Farmos Yhtymy Oy Method for the immunlolgical determinition of the carboxyterminal propeptide of type i procollagen
GB9105893D0 (en) * 1991-03-20 1991-05-08 Orion Yhtymae Oy Bone resorption assay based on a peptide liberated during collagen degradation
ATE161543T1 (de) * 1992-01-31 1998-01-15 David Jeston Baylink Aminoterminale prokollagen 1(i) peptide
DE4225038C2 (de) * 1992-07-29 1995-11-30 Boehringer Mannheim Gmbh Herstellung und Verwendung von Antikörpern gegen Kollagen

Also Published As

Publication number Publication date
FI960392A (fi) 1996-01-29
CA2167496A1 (en) 1995-02-09
EP0711415B1 (de) 1998-07-22
WO1995004282A1 (de) 1995-02-09
DK0711415T3 (da) 1999-04-26
EP0711415A1 (de) 1996-05-15
JP2703116B2 (ja) 1998-01-26
FI960392A0 (fi) 1996-01-29
JPH08509294A (ja) 1996-10-01
DE59406512D1 (de) 1998-08-27
ATE168779T1 (de) 1998-08-15

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