DE19980834T1 - Knorpel-Resorptionstests - Google Patents

Knorpel-Resorptionstests

Info

Publication number
DE19980834T1
DE19980834T1 DE19980834T DE19980834T DE19980834T1 DE 19980834 T1 DE19980834 T1 DE 19980834T1 DE 19980834 T DE19980834 T DE 19980834T DE 19980834 T DE19980834 T DE 19980834T DE 19980834 T1 DE19980834 T1 DE 19980834T1
Authority
DE
Germany
Prior art keywords
cartilage
seq
vivo
measurement
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19980834T
Other languages
English (en)
Inventor
David R Eyre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Washington Research Foundation
Original Assignee
Washington Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Washington Research Foundation filed Critical Washington Research Foundation
Publication of DE19980834T1 publication Critical patent/DE19980834T1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/105—Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE19980834T 1998-06-19 1999-06-17 Knorpel-Resorptionstests Withdrawn DE19980834T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8982398P 1998-06-19 1998-06-19
PCT/US1999/013716 WO1999066327A2 (en) 1998-06-19 1999-06-17 Cartilage resorption assays

Publications (1)

Publication Number Publication Date
DE19980834T1 true DE19980834T1 (de) 2001-06-13

Family

ID=22219750

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19980834T Withdrawn DE19980834T1 (de) 1998-06-19 1999-06-17 Knorpel-Resorptionstests
DE69926888T Expired - Lifetime DE69926888T2 (de) 1998-06-19 1999-06-17 Knorpelresorptionsassays

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69926888T Expired - Lifetime DE69926888T2 (de) 1998-06-19 1999-06-17 Knorpelresorptionsassays

Country Status (8)

Country Link
US (1) US6255056B1 (de)
EP (1) EP1088228B1 (de)
JP (1) JP4436972B2 (de)
AT (1) ATE302949T1 (de)
AU (1) AU4692199A (de)
DE (2) DE19980834T1 (de)
DK (1) DK1088228T3 (de)
WO (1) WO1999066327A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050124071A1 (en) * 2003-09-30 2005-06-09 Kraus Virginia B. Methods and compositions for diagnosing musculoskeletal, arthritic and joint disorders by biomarker dating

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4628027A (en) 1982-05-19 1986-12-09 Molecular Engineering Associates, Ltd. Vitro diagnostic methods using monoclonal antibodies against connective tissue proteins
US5316914A (en) 1986-09-04 1994-05-31 Fuji Yakuhin Kogyo Kabushiki Kaisha Method for determining human collagen peptides by way of enzyme immunoassay
US5476765A (en) * 1987-01-09 1995-12-19 United Biomedical, Inc. Synthetic peptide compositions with immunoreactivities to antibodies to HTLV and as vaccines
GB2205643B (en) 1987-05-08 1991-03-13 Farmos Group Limited Type iii collagen degradation assay
US4973666A (en) 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
US5702909A (en) 1987-11-06 1997-12-30 Washington Research Foundation Methods of detecting collagen type II degradation in vivo
US5320970A (en) 1987-11-06 1994-06-14 Washington Research Foundation Detection of collagen degradation in vivo
US5300434A (en) 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
GB8815174D0 (en) 1988-06-25 1988-08-03 Rowett Research Inst Method of monitoring collagen degradation
GB9105893D0 (en) 1991-03-20 1991-05-08 Orion Yhtymae Oy Bone resorption assay based on a peptide liberated during collagen degradation
DE4225038C2 (de) 1992-07-29 1995-11-30 Boehringer Mannheim Gmbh Herstellung und Verwendung von Antikörpern gegen Kollagen
CA2148132A1 (en) 1992-12-04 1994-06-23 Anthony Robin Poole Immunoassay for the measurement of collagen cleavage in cartilage
CA2152667C (en) 1992-12-28 2003-02-11 David J. Baylink Bone resorption assay
US6653450B1 (en) 1993-01-28 2003-11-25 Cohesion Technologies, Inc. Mutated recombinant collagens
US5541295A (en) 1993-02-12 1996-07-30 The Board Of Governors For Higher Education State Of Rhode Island And Providence Plantations Detection of type II collagen and its peptides
CA2167496A1 (en) 1993-07-28 1995-02-09 Werner Naser Immunoassay for the detection of collagen or collagen fragments
DK104093D0 (da) 1993-09-17 1993-09-17 Osteometer A S Fremgangsmaade til bestemmelse af collagen-fragmenter i legemsvaesker, test-kit og midler til udoevelse af fremgangsmaaden og anvendelse af fremgangsmaaden til diagnosticering af lidelser associeret til collagen-metabolismen
EP0787301B1 (de) 1994-10-17 2001-02-14 Osteometer Biotech AS Einschätzung der fragmentierungsmuster von kollagen in körperflüssigkeiten und diagnose von mit dem kollagenmetabolismus zusammenhängenden störungen
EP0718309B1 (de) 1994-12-23 1999-04-07 Roche Diagnostics GmbH Antigene und Antikörper zum Nachweis von Kollagen I
US5750647A (en) 1995-05-19 1998-05-12 Washington Research Foundation Synthetic peptide analogs of NTx

Also Published As

Publication number Publication date
DE69926888T2 (de) 2006-03-30
EP1088228B1 (de) 2005-08-24
WO1999066327A3 (en) 2000-03-09
DE69926888D1 (de) 2005-09-29
DK1088228T3 (da) 2006-01-02
EP1088228A2 (de) 2001-04-04
JP4436972B2 (ja) 2010-03-24
US6255056B1 (en) 2001-07-03
WO1999066327A2 (en) 1999-12-23
AU4692199A (en) 2000-01-05
ATE302949T1 (de) 2005-09-15
JP2002518676A (ja) 2002-06-25

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination