ES2191015T3 - Procedimiento y kit de ensayo de reticulacion de piridinio. - Google Patents
Procedimiento y kit de ensayo de reticulacion de piridinio.Info
- Publication number
- ES2191015T3 ES2191015T3 ES93918536T ES93918536T ES2191015T3 ES 2191015 T3 ES2191015 T3 ES 2191015T3 ES 93918536 T ES93918536 T ES 93918536T ES 93918536 T ES93918536 T ES 93918536T ES 2191015 T3 ES2191015 T3 ES 2191015T3
- Authority
- ES
- Spain
- Prior art keywords
- pyridinium
- piridinia
- reticulation
- kit
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
UN METODO PARA ANALIZAR LA ACTIVIDAD DE DEGRADACION DEL COLAGENO DE LOS HUESOS EN UN SER HUMANO. SEGUN EL METODO SE HACE REACCIONAR UNA MUESTRA DE ORINA HUMANA CON UN ANTICUERPO MONOCLONAL QUE (I) SEA CAPAZ DE REACCIONAR INMUNOESPECIFICAMENTE CON ENTRECRUZAMIENTOS DE PIRIDINIO SELECCIONADOS DEL GRUPO QUE CONSISTE EN PIRIDINOLINA LIBRE NATIVA Y DESOXIPIRIDINOLINA LIBRE NATIVA Y (II) TENGA UNA RELACION DE REACTIVIDAD HACIA LOS ENTRECRUZAMIENTOS DE PIRIDINIO SELECCIONADOS Y LOS PEPTIDOS DE PIRIDINIO URINARIOS SUPERIOR A 1.000 DALTONS EN PESO MOLECULAR O SUPERIOR A 5:1 APROXIMADAMENTE. SE FORMA UN INMUNOCOMPLEJO ENTRE EL REACTIVO DE ANTICUERPO Y LOS ENTRECRUZAMIENTOS DE PIRIDINIO SELECCIONADOS QUE SE ENCUENTRAN PRESENTES EN LA MUESTRA Y SE MIDE LA CANTIDAD DEL INMUNOCOMPLEJO. TAMBIEN SE PRESENTAN LOS REACTIVOS DE ANTICUERPOS Y LOS KITS QUE SE PUEDEN UTILIZAR EN EL METODO.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92290692A | 1992-07-31 | 1992-07-31 | |
US99288892A | 1992-12-17 | 1992-12-17 | |
US3757193A | 1993-03-26 | 1993-03-26 | |
US3760293A | 1993-03-26 | 1993-03-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2191015T3 true ES2191015T3 (es) | 2003-09-01 |
Family
ID=27488453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93918536T Expired - Lifetime ES2191015T3 (es) | 1992-07-31 | 1993-07-30 | Procedimiento y kit de ensayo de reticulacion de piridinio. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0653067B1 (es) |
JP (2) | JP3626182B2 (es) |
AT (1) | ATE231618T1 (es) |
AU (1) | AU684047B2 (es) |
CA (1) | CA2140921C (es) |
DE (1) | DE69332655T2 (es) |
ES (1) | ES2191015T3 (es) |
WO (1) | WO1994003814A2 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5756361A (en) * | 1992-12-17 | 1998-05-26 | Metra Biosystems, Inc. | Screening method for periodontal disease |
US5661039A (en) * | 1995-03-01 | 1997-08-26 | Metra Biosystems, Inc. | Perspiration assay for bone resorption |
CA2297555A1 (en) * | 1997-07-31 | 1999-02-11 | Metra Biosystems, Inc. | Collagen-peptide assay method |
AU5776400A (en) * | 1999-06-30 | 2001-01-31 | Quidel Corporation | Method and kit for measuring total pyridinium crosslinks |
US20060046273A1 (en) * | 2004-08-27 | 2006-03-02 | Lin-Zhi International Inc. | Homogeneous enzyme immunoassay for oral fluid |
CN105801688A (zh) * | 2016-04-14 | 2016-07-27 | 苏州博源医疗科技有限公司 | 脱氧吡啶酚免疫原、抗体和检测试剂及制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4973666A (en) * | 1987-11-06 | 1990-11-27 | Washington Research Foundation | Peptide fragments containing HP and LP cross-links |
GB8815174D0 (en) * | 1988-06-25 | 1988-08-03 | Rowett Research Inst | Method of monitoring collagen degradation |
-
1993
- 1993-07-30 EP EP93918536A patent/EP0653067B1/en not_active Expired - Lifetime
- 1993-07-30 WO PCT/US1993/007203 patent/WO1994003814A2/en active IP Right Grant
- 1993-07-30 AU AU47955/93A patent/AU684047B2/en not_active Ceased
- 1993-07-30 CA CA002140921A patent/CA2140921C/en not_active Expired - Fee Related
- 1993-07-30 JP JP50547094A patent/JP3626182B2/ja not_active Expired - Fee Related
- 1993-07-30 DE DE69332655T patent/DE69332655T2/de not_active Expired - Fee Related
- 1993-07-30 AT AT93918536T patent/ATE231618T1/de not_active IP Right Cessation
- 1993-07-30 ES ES93918536T patent/ES2191015T3/es not_active Expired - Lifetime
-
2004
- 2004-08-25 JP JP2004245790A patent/JP2005010174A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO1994003814A2 (en) | 1994-02-17 |
WO1994003814A3 (en) | 1994-04-14 |
ATE231618T1 (de) | 2003-02-15 |
AU684047B2 (en) | 1997-12-04 |
DE69332655T2 (de) | 2003-11-27 |
JPH07509780A (ja) | 1995-10-26 |
DE69332655D1 (de) | 2003-02-27 |
AU4795593A (en) | 1994-03-03 |
CA2140921C (en) | 2003-09-30 |
JP2005010174A (ja) | 2005-01-13 |
CA2140921A1 (en) | 1994-02-01 |
JP3626182B2 (ja) | 2005-03-02 |
EP0653067A1 (en) | 1995-05-17 |
EP0653067B1 (en) | 2003-01-22 |
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