DE69526056D1 - Immunologisches Testverfahren zur Quantifizierung von PEG-modifiziertem humanem Granulozyten-Kolonie-Stimulierender-Faktor - Google Patents

Immunologisches Testverfahren zur Quantifizierung von PEG-modifiziertem humanem Granulozyten-Kolonie-Stimulierender-Faktor

Info

Publication number
DE69526056D1
DE69526056D1 DE69526056T DE69526056T DE69526056D1 DE 69526056 D1 DE69526056 D1 DE 69526056D1 DE 69526056 T DE69526056 T DE 69526056T DE 69526056 T DE69526056 T DE 69526056T DE 69526056 D1 DE69526056 D1 DE 69526056D1
Authority
DE
Germany
Prior art keywords
stimulating factor
colony stimulating
human granulocyte
peg
granulocyte colony
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69526056T
Other languages
English (en)
Other versions
DE69526056T2 (de
Inventor
Nobuo Hanai
Akiko Furuya
Motoo Yamasaki
Satoshi Kobayashi
Takashi Kuwabara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Kirin Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of DE69526056D1 publication Critical patent/DE69526056D1/de
Publication of DE69526056T2 publication Critical patent/DE69526056T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69526056T 1994-12-15 1995-12-15 Immunologisches Testverfahren zur Quantifizierung von PEG-modifiziertem humanem Granulozyten-Kolonie-Stimulierender-Faktor Expired - Lifetime DE69526056T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP31176394A JP3708151B2 (ja) 1994-12-15 1994-12-15 Ｐｅｇ化したヒト顆粒球コロニー刺激因子の定量法

Publications (2)

Publication Number Publication Date
DE69526056D1 true DE69526056D1 (de) 2002-05-02
DE69526056T2 DE69526056T2 (de) 2003-04-03

Family

ID=18021197

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69526056T Expired - Lifetime DE69526056T2 (de) 1994-12-15 1995-12-15 Immunologisches Testverfahren zur Quantifizierung von PEG-modifiziertem humanem Granulozyten-Kolonie-Stimulierender-Faktor

Country Status (6)

Country Link
US (1) US5939280A (de)
EP (1) EP0721958B1 (de)
JP (1) JP3708151B2 (de)
AT (1) ATE215095T1 (de)
DE (1) DE69526056T2 (de)
ES (1) ES2173146T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030053982A1 (en) 1994-09-26 2003-03-20 Kinstler Olaf B. N-terminally chemically modified protein compositions and methods
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
EA200400067A1 (ru) * 1999-01-29 2004-04-29 Эмджен Инк. Конъюгаты гксф
EP1369429A1 (de) * 1999-01-29 2003-12-10 F. Hoffmann-La Roche Ag GCSF Konjugate
KR100735784B1 (ko) 2005-07-20 2007-07-06 재단법인 목암생명공학연구소 인간 과립구콜로니자극인자 변이체 및 이의 화학적 접합물

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB331186A (en) * 1929-03-18 1930-06-18 Bataafsche Petroleum A process for the manufacture of valuable products from ethylene and/or its homologues
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4778752A (en) * 1983-10-11 1988-10-18 Scripps Clinic And Research Foundation Receptors specific for hapten-modified self proteins
NZ218336A (en) * 1985-12-09 1991-08-27 Kirin Amgen Inc Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf)
US5194592A (en) * 1986-12-23 1993-03-16 Kyowa Hakko Kogyo Co. Ltd. Monoclonal antibodies to novel polypeptide derivatives of human granulocyte colony stimulating factor
US5362853A (en) * 1986-12-23 1994-11-08 Kyowa Hakko Kogyo Co., Ltd. Polypeptide derivatives of human granulocyte colony stimulating factor
JP2618618B2 (ja) * 1988-03-04 1997-06-11 協和醗酵工業株式会社 抗ｇ−ｃｓｆ誘導体、ｎｄ２８モノクローナル抗体
US5214132A (en) * 1986-12-23 1993-05-25 Kyowa Hakko Kogyo Co., Ltd. Polypeptide derivatives of human granulocyte colony stimulating factor
JPS63180860A (ja) * 1987-01-22 1988-07-25 Kyowa Hakko Kogyo Co Ltd 抗ｇ−ｃｓｆモノクロ−ナル抗体
WO1990006952A1 (en) * 1988-12-22 1990-06-28 Kirin-Amgen, Inc. Chemically modified granulocyte colony stimulating factor
JP3051145B2 (ja) * 1990-08-28 2000-06-12 住友製薬株式会社 新規なポリエチレングリコール誘導体修飾ペプチド
US6565841B1 (en) * 1991-03-15 2003-05-20 Amgen, Inc. Pulmonary administration of granulocyte colony stimulating factor
US5336782A (en) * 1991-04-24 1994-08-09 Kuraray Co., Ltd. Long chain carboxylic acid imide ester
JPH05115197A (ja) * 1991-10-21 1993-05-07 Fanuc Ltd リラクタンスモータ用ロータリエンコーダと駆動装置
JPH05115297A (ja) * 1991-10-29 1993-05-14 Otsuka Pharmaceut Co Ltd ヒトｇ−ｃｓｆ抗体及びヒトｇ−ｃｓｆの測定法
US5581476A (en) * 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
US5298410A (en) * 1993-02-25 1994-03-29 Sterling Winthrop Inc. Lyophilized formulation of polyethylene oxide modified proteins with increased shelf-life
US5605976A (en) * 1995-05-15 1997-02-25 Enzon, Inc. Method of preparing polyalkylene oxide carboxylic acids
US5536382A (en) * 1994-05-23 1996-07-16 Advanced Molecular Systems, Inc. Capillary electrophoresis assay method useful for the determination of constituents of a clinical sample
US5593666A (en) * 1994-08-16 1997-01-14 The University Of Tennessee Research Corp. Methods and compositions for treating thrombocytopenia

Also Published As

Publication number Publication date
JPH08165300A (ja) 1996-06-25
DE69526056T2 (de) 2003-04-03
US5939280A (en) 1999-08-17
EP0721958A2 (de) 1996-07-17
ATE215095T1 (de) 2002-04-15
ES2173146T3 (es) 2002-10-16
EP0721958B1 (de) 2002-03-27
EP0721958A3 (de) 1996-12-18
JP3708151B2 (ja) 2005-10-19

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8327 Change in the person/name/address of the patent owner

Owner name: KYOWA HAKKO KIRIN CO., LTD., TOKYO, JP