ES2133529T3 - Procedimiento para tipificar aislamientos de hcv. - Google Patents
Procedimiento para tipificar aislamientos de hcv.Info
- Publication number
- ES2133529T3 ES2133529T3 ES94901891T ES94901891T ES2133529T3 ES 2133529 T3 ES2133529 T3 ES 2133529T3 ES 94901891 T ES94901891 T ES 94901891T ES 94901891 T ES94901891 T ES 94901891T ES 2133529 T3 ES2133529 T3 ES 2133529T3
- Authority
- ES
- Spain
- Prior art keywords
- hcv
- nucleotide
- isolated
- test
- insulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
- C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Abstract
LA INVENCION SE REFIERE A UN PROCESO PARA TIPIFICAR GENES DE CUALQUIER AISLADO DE HCV PRESENTE EN UNA MUESTRA BIOLOGICA, PREVIAMENTE IDENTIFICADA POR SER POSITIVA HCV, Y PARA CLASIFICAR DICHO AISLADO SEGUN EL PORCENTAJE DE HOMOLOGIA CON OTROS AISLADOS HCV QUE CONSTAN DE LOS PASOS DE: ENTRANDO EN CONTACTO DICHA MUESTRA EN LA QUE LOS RIBONUCLEOTIDOS O DESOXIRIBONUCLEOTIDOS SE HAN HECHO ACCESIBLES, SI SE NECESITA, BAJO DESNATURIZACION ADECUADA, CON AL MENOS UNA PRUEBA DE UNOS 10 A UNOS 40 NUCLEOTIDOS, TENIENDO DICHA PRUEBA TENDENCIA A HIBRIZARSE A UNA REGION EN EL DOMINIO QUE SE EXTIENDE DESDE UN NUCLEOTIDO EN LA POSICION -291 A UN NUCLEOTIDO EN LA POSICION -66 DE LA REGION 5'' NO TRADUCIDA DE UNO DE LOS AISLADOS DE HCV REPRESENTADOS POR SUS SECUENCIAS DE CDNA, CON DICHA NUMERACION DE LA POSICION COMENZANDO CON EL PRIMER CODON DE ATG DEL MARCO DE LECTURA ABIERTO CODIFICANDO LA POLIPROTEINA, O DICHA PRUEBA QUE ES COMPLEMENTARIA A LAS PRUEBAS ARRIBA DEFINIDAS; DETECTANDO LOS COMPLEJOS LA POSIBILIDAD FORMADA ENTRE DICHA PRUEBA Y LA SECUENCIA DE NUCLEOTIDO DEL AISLADO HCV PARA SER IDENTIFICADO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP92403222 | 1992-11-27 | ||
EP93402129 | 1993-08-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2133529T3 true ES2133529T3 (es) | 1999-09-16 |
Family
ID=26132445
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94901891T Expired - Lifetime ES2133529T3 (es) | 1992-11-27 | 1993-11-26 | Procedimiento para tipificar aislamientos de hcv. |
Country Status (13)
Country | Link |
---|---|
US (8) | US5846704A (es) |
EP (3) | EP1197568B1 (es) |
JP (2) | JP4251407B2 (es) |
AT (2) | ATE507312T1 (es) |
AU (1) | AU681612B2 (es) |
CA (1) | CA2128528C (es) |
DE (2) | DE69334357D1 (es) |
DK (1) | DK0637342T3 (es) |
ES (1) | ES2133529T3 (es) |
GR (1) | GR3030641T3 (es) |
HK (1) | HK1047961A1 (es) |
SG (1) | SG46456A1 (es) |
WO (1) | WO1994012670A2 (es) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU681612B2 (en) | 1992-11-27 | 1997-09-04 | N.V. Innogenetics S.A. | Process for typing of hcv isolates |
US7258977B1 (en) | 1992-11-27 | 2007-08-21 | Innogenetics N.V. | Process for typing of HCV isolates |
JP4472786B2 (ja) * | 1993-03-05 | 2010-06-02 | ジェムスター ディベロプメント コーポレイション | テレビジョン番組情報を通信する方法及びシステム |
US7255997B1 (en) | 1993-04-27 | 2007-08-14 | N.V. Innogenetics S.A. | Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents |
ATE552340T1 (de) * | 1993-04-27 | 2012-04-15 | Innogenetics Nv | Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln |
US5830635A (en) * | 1995-03-31 | 1998-11-03 | Agnello; Vincent | Method of detecting hepatitis C virus in tissues |
US20020081577A1 (en) * | 1995-06-06 | 2002-06-27 | Robert L. Kilkuskie | Oligonucleotides speciific for hepatitis c virus |
US6087093A (en) * | 1996-01-26 | 2000-07-11 | Innogenetics N.V. | Method for detection of drug-induced mutations in the reverse transcriptase gene |
ZA973367B (en) | 1996-04-19 | 1997-11-18 | Innogenetics Nv | Method for typing and detecting HBV. |
FR2750505B1 (fr) | 1996-06-27 | 1998-10-16 | Appligene Oncor | Procede de preparation de supports d'analyse de substances chimiques ou biologiques presentant un ensemble ordonne de zones de reaction |
EP2295988A2 (en) | 1996-12-31 | 2011-03-16 | High Throughput Genomics, Inc. | Multiplexed molecular analysis apparatus and its fabrication method |
US7101672B2 (en) * | 1998-05-05 | 2006-09-05 | Third Wave Technologies, Inc. | Target-dependent reactions using structure-bridging oligonucleotides |
IL122299A (en) * | 1997-11-25 | 2003-11-23 | Broadcom Corp | Video encoding device |
US20030096232A1 (en) | 1997-12-19 | 2003-05-22 | Kris Richard M. | High throughput assay system |
WO1999060158A1 (fr) * | 1998-05-19 | 1999-11-25 | Laboratory Of Molecular Biophotonics | Phase solide utilisee pour detecter de l'acide nucleique et procede de detection d'acide nucleique |
ES2342593T3 (es) | 1998-07-17 | 2010-07-09 | United Video Properties, Inc. | Sistema de guia interactivo de programas de television que tienen multiples dispositivos dentro de una casa. |
AR020608A1 (es) | 1998-07-17 | 2002-05-22 | United Video Properties Inc | Un metodo y una disposicion para suministrar a un usuario acceso remoto a una guia de programacion interactiva por un enlace de acceso remoto |
US6638714B1 (en) * | 1999-02-03 | 2003-10-28 | Ortho-Clinical Diagnostics, Inc. | Oligonucleotide primers for efficient detection of hepatitis C virus (HCV) and methods of use thereof |
US6623919B1 (en) * | 1999-02-03 | 2003-09-23 | Ortho-Clinical Diagnostics, Inc | Oligonucleotide primers for efficient multiplex detection of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) and methods of use thereof |
AU2006203092B2 (en) * | 1999-02-03 | 2009-11-12 | Ortho-Clinical Diagnostics, Inc. | Oligonucleotide primers for efficient detection of hepatitis C virus (HCV) and methods of use thereof |
GB0016836D0 (en) | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (1) |
US6586584B2 (en) | 2001-01-29 | 2003-07-01 | Becton, Dickinson And Company | Sequences and methods for detection of Hepatitis C virus |
RU2229719C2 (ru) * | 2001-03-27 | 2004-05-27 | Кабусики Кайся Тосиба | Обнаружение имеющей отношение к заболеванию нуклеиновой кислоты |
US20030152942A1 (en) * | 2001-05-09 | 2003-08-14 | Lance Fors | Nucleic acid detection in pooled samples |
US7196183B2 (en) * | 2001-08-31 | 2007-03-27 | Innogenetics N.V. | Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent |
US7877273B2 (en) * | 2002-01-08 | 2011-01-25 | Fredric David Abramson | System and method for evaluating and providing nutrigenomic data, information and advice |
GB0200526D0 (en) * | 2002-01-11 | 2002-02-27 | Science And Technology The | Methods |
FR2855832B1 (fr) | 2003-06-03 | 2007-09-14 | Biomerieux Sa | Procede de diagnostic et/ou de pronostic d'un syndrome septique |
FR2857375B1 (fr) | 2003-07-10 | 2007-11-09 | Biomerieux Sa | Procede de detection et/ou d'identification de bacteries de genre staphylococcus |
EP1536024B1 (en) * | 2003-08-29 | 2016-08-17 | Fujirebio Europe N.V. | New hepatitis c virus clade and phototype sequences thereof |
US8124747B2 (en) | 2003-08-29 | 2012-02-28 | Innogenetics | HCV clade and prototype sequences thereof |
WO2005067643A2 (en) * | 2004-01-07 | 2005-07-28 | Third Wave Technologies, Inc. | Determination of hepatitis c virus genotype |
US20090209432A1 (en) * | 2004-04-06 | 2009-08-20 | Flinders Technologies Pty. Ltd. | Detecting targets using nucleic acids having both a variable region and a conserved region |
US8806533B1 (en) | 2004-10-08 | 2014-08-12 | United Video Properties, Inc. | System and method for using television information codes |
FR2881437B1 (fr) | 2005-01-31 | 2010-11-19 | Biomerieux Sa | Procede pour le diagnostic/pronostic d'un syndrome septique |
US8927208B2 (en) | 2005-03-30 | 2015-01-06 | Labo Bio-Medical Investments B.V. | Identification of beta-papillomavirus DNA by type-specific reverse hybridization |
US7465561B2 (en) * | 2005-06-30 | 2008-12-16 | Roche Molecular Systems, Inc. | Probes and methods for hepatitis C virus typing using single probe analysis |
US20070207455A1 (en) * | 2005-11-17 | 2007-09-06 | Third Wave Technologies, Inc. | Compositions and methods for detecting an HCV-1 subtype |
US7544473B2 (en) * | 2006-01-23 | 2009-06-09 | Population Genetics Technologies Ltd. | Nucleic acid analysis using sequence tokens |
FR2906537A1 (fr) | 2006-09-28 | 2008-04-04 | Biomerieux Sa | Procede de diagnostic in vitro du cancer broncho-pulmonaire par detection des transcrits majoritaires alternatifs du gene klk8 codant la kallicreine 8 et son utilisation pour le pronostic de survie |
WO2008046923A2 (en) | 2006-10-20 | 2008-04-24 | Innogenetics N.V. | Methodology for analysis of sequence variations within the hcv ns3/4a genomic region |
EP2463389A1 (en) | 2006-10-20 | 2012-06-13 | Innogenetics N.V. | Methodology for analysis of sequence variations within the HCV NS5B genomic region |
US8418206B2 (en) | 2007-03-22 | 2013-04-09 | United Video Properties, Inc. | User defined rules for assigning destinations of content |
WO2009022939A1 (fr) * | 2007-08-09 | 2009-02-19 | Uchrezhdenie Rossiiskoi Akademii Nauk Institut Molekulyarnoi Biologii Im. V.A. Engelgardta Ran (Imb Ran) | Procédé d'identification du génotype et du sous-type du virus de l'hépatite c sur une biopuce |
US8601526B2 (en) | 2008-06-13 | 2013-12-03 | United Video Properties, Inc. | Systems and methods for displaying media content and media guidance information |
US8258283B2 (en) * | 2008-12-29 | 2012-09-04 | Lg Life Sciences Ltd. | Method for detection of HCV at the real time PCR with intercalating dye |
US20100240049A1 (en) | 2009-01-16 | 2010-09-23 | Cepheid | Methods of Detecting Cervical Cancer |
ES2556771T3 (es) | 2009-01-19 | 2016-01-20 | bioMérieux S.A. | Procedimientos para determinar la susceptibilidad de contraer una infección nosocomial en un paciente y para establecer un pronóstico de evolución de un síndrome séptico |
US20100323344A1 (en) * | 2009-06-18 | 2010-12-23 | Ferguson Monique R | Detection of hepatitis C virus RNA |
US9204193B2 (en) | 2010-05-14 | 2015-12-01 | Rovi Guides, Inc. | Systems and methods for media detection and filtering using a parental control logging application |
US9422598B2 (en) | 2010-06-04 | 2016-08-23 | Biomerieux | Method and kit for the prognosis of colorectal cancer |
US9110079B2 (en) | 2010-09-29 | 2015-08-18 | Biomerieux | Method and kit for establishing an in vitro prognosis on a patient exhibiting SIRS |
FR2970975B1 (fr) | 2011-01-27 | 2016-11-04 | Biomerieux Sa | Procede et kit pour determiner in vitro le statut immunitaire d'un individu |
WO2012129758A1 (en) | 2011-03-25 | 2012-10-04 | Biomerieux | Method and kit for determining in vitro probability for individual to suffer from colorectal cancer |
EP2722398B1 (en) | 2012-10-18 | 2017-07-12 | F. Hoffmann-La Roche AG | Dual probe assay for the detection of HCV |
FR3000966B1 (fr) | 2013-01-11 | 2016-10-28 | Biomerieux Sa | Procede pour etablir in vitro un pronostic de severite chez un patient en choc septique |
EP3000897B1 (en) | 2013-05-21 | 2019-10-16 | Biomérieux | Colorectal cancer prognosis agent kit |
CA3040907A1 (en) * | 2016-10-19 | 2018-04-26 | Gen-Probe Incorporated | Compositions and methods for detecting or quantifying hepatitis c virus |
EP3643792B1 (en) | 2018-10-24 | 2021-09-15 | Fujirebio Europe N.V. | Detection and analysis of sequence variations in a target nucleic acid |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8810400D0 (en) * | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
JPH02167081A (ja) * | 1988-12-21 | 1990-06-27 | Tetsuo Nakamura | 非A非B型肝炎ウイルスゲノムRNA、cDNAおよびウイルス抗原蛋白質 |
US5176994A (en) * | 1988-12-21 | 1993-01-05 | Immuno Japan Inc. | Non-A, Non-B hepatitis virus genome RNA, cDNA and virus antigen protein |
US5629158A (en) | 1989-03-22 | 1997-05-13 | Cemu Bitecknik Ab | Solid phase diagnosis of medical conditions |
US5043272A (en) * | 1989-04-27 | 1991-08-27 | Life Technologies, Incorporated | Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers |
JP2802125B2 (ja) * | 1989-06-23 | 1998-09-24 | キヤノン株式会社 | 核酸の検出方法 |
US5372928A (en) * | 1989-09-15 | 1994-12-13 | Chiron Corporation | Hepatitis C virus isolates |
GB8924989D0 (en) * | 1989-11-06 | 1989-12-28 | Scotgen Ltd | Method and device for the detection of antibiotic resistance |
US5252743A (en) * | 1989-11-13 | 1993-10-12 | Affymax Technologies N.V. | Spatially-addressable immobilization of anti-ligands on surfaces |
US5629153A (en) * | 1990-01-10 | 1997-05-13 | Chiron Corporation | Use of DNA-dependent RNA polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays |
EP0461863A1 (en) * | 1990-06-12 | 1991-12-18 | Immuno Japan Inc. | Oligonucleotide primers, and their application for high-fidelity detection of non-A, non-B hepatitis virus |
ATE150086T1 (de) * | 1990-07-11 | 1997-03-15 | Shionogi & Co | Cdns-sequenz und detektion des hepatitis c-virus |
EP0543924B1 (en) * | 1990-08-10 | 1997-06-18 | Chiron Corporation | Nanbv diagnostics: polynucleotides useful for screening for hepatitis c virus |
US5620852A (en) | 1990-11-14 | 1997-04-15 | Hri Research, Inc. | Nucleic acid preparation methods |
WO1992010588A1 (en) * | 1990-12-06 | 1992-06-25 | Affymax Technologies N.V. | Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides |
EP0511559A1 (en) * | 1991-04-30 | 1992-11-04 | F.Hoffmann-La Roche & Co. Aktiengesellschaft | Oligonucleotide probe reagent |
SK284205B6 (sk) * | 1991-05-08 | 2004-10-05 | Chiron Corporation | Prirodzene sa nevyskytujúca nukleová kyselina, spôsob tvorby hybridizačného produktu a spôsob detekcie genotypov HCV |
US6190864B1 (en) * | 1991-05-08 | 2001-02-20 | Chiron Corporation | HCV genomic sequences for diagnostics and therapeutics |
US5428145A (en) * | 1991-08-09 | 1995-06-27 | Immuno Japan, Inc. | Non-A, non-B, hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems |
DE69233083T2 (de) * | 1991-08-27 | 2003-12-18 | Hoffmann La Roche | Primers und Sondern zum Nachweis von Hepatitis C |
US5427909A (en) * | 1991-09-09 | 1995-06-27 | Immuno Japan Inc. | Oligonucleotides and determination system of HCV genotypes |
JPH06502770A (ja) | 1991-09-12 | 1994-03-31 | シーダーズ−サイナイ・メディカル・センター | C型肝炎ウイルスrnaの直接検出法 |
US5173994A (en) * | 1992-01-14 | 1992-12-29 | The United States Of America As Represented By The Secretary Of Agriculture | Fiber cleaning apparatus with air flow deflector |
WO1993023569A1 (en) * | 1992-05-11 | 1993-11-25 | Ribozyme Pharmaceuticals, Inc. | Method and reagent for inhibiting viral replication |
AU681612B2 (en) | 1992-11-27 | 1997-09-04 | N.V. Innogenetics S.A. | Process for typing of hcv isolates |
JPH06153961A (ja) | 1992-11-27 | 1994-06-03 | Imuno Japan:Kk | C型肝炎ウイルス部分遺伝子、ならびにc型肝炎ウイルス遺 伝子の高感度検出法 |
US5820852A (en) * | 1996-11-26 | 1998-10-13 | The Proctor & Gamble Company | Oral compositions containing fluoride, pyrophosphate, and peroxide |
-
1993
- 1993-11-26 AU AU56282/94A patent/AU681612B2/en not_active Expired
- 1993-11-26 CA CA2128528A patent/CA2128528C/en not_active Expired - Lifetime
- 1993-11-26 DK DK94901891T patent/DK0637342T3/da active
- 1993-11-26 WO PCT/EP1993/003325 patent/WO1994012670A2/en active IP Right Grant
- 1993-11-26 ES ES94901891T patent/ES2133529T3/es not_active Expired - Lifetime
- 1993-11-26 US US08/256,568 patent/US5846704A/en not_active Expired - Lifetime
- 1993-11-26 AT AT01121347T patent/ATE507312T1/de not_active IP Right Cessation
- 1993-11-26 JP JP51276794A patent/JP4251407B2/ja not_active Expired - Lifetime
- 1993-11-26 AT AT94901891T patent/ATE179459T1/de active
- 1993-11-26 DE DE69334357T patent/DE69334357D1/de not_active Expired - Lifetime
- 1993-11-26 EP EP01121347A patent/EP1197568B1/en not_active Expired - Lifetime
- 1993-11-26 DE DE69324678T patent/DE69324678T2/de not_active Expired - Lifetime
- 1993-11-26 EP EP98117538A patent/EP0905258A3/en not_active Withdrawn
- 1993-11-26 EP EP94901891A patent/EP0637342B1/en not_active Expired - Lifetime
- 1993-11-26 SG SG1996004862A patent/SG46456A1/en unknown
-
1998
- 1998-03-10 US US09/038,369 patent/US6171784B1/en not_active Expired - Lifetime
- 1998-03-19 US US09/044,665 patent/US6051696A/en not_active Expired - Lifetime
-
1999
- 1999-06-30 GR GR990401727T patent/GR3030641T3/el unknown
- 1999-08-23 US US09/378,900 patent/US6495670B1/en not_active Expired - Fee Related
-
2001
- 2001-07-06 US US09/899,044 patent/US6548244B2/en not_active Expired - Fee Related
- 2001-07-06 US US09/899,302 patent/US6887985B2/en not_active Expired - Fee Related
- 2001-07-06 US US09/899,082 patent/US6891026B2/en not_active Expired - Fee Related
-
2002
- 2002-10-17 HK HK02107543.5A patent/HK1047961A1/zh unknown
-
2004
- 2004-04-13 US US10/822,711 patent/US7258982B2/en not_active Expired - Fee Related
- 2004-11-11 JP JP2004328242A patent/JP2005040145A/ja active Pending
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