ATE162802T1 - Amyloid-peptide - Google Patents

Amyloid-peptide

Info

Publication number
ATE162802T1
ATE162802T1 AT88303803T AT88303803T ATE162802T1 AT E162802 T1 ATE162802 T1 AT E162802T1 AT 88303803 T AT88303803 T AT 88303803T AT 88303803 T AT88303803 T AT 88303803T AT E162802 T1 ATE162802 T1 AT E162802T1
Authority
AT
Austria
Prior art keywords
amylin
kcntat
found
peptides
synthetic
Prior art date
Application number
AT88303803T
Other languages
English (en)
Inventor
Garth James Smith Cooper
Anthony Charles Willis
Original Assignee
Amylin Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylin Pharmaceuticals Inc filed Critical Amylin Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE162802T1 publication Critical patent/ATE162802T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT88303803T 1987-04-27 1988-04-27 Amyloid-peptide ATE162802T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878709871A GB8709871D0 (en) 1987-04-27 1987-04-27 Peptides

Publications (1)

Publication Number Publication Date
ATE162802T1 true ATE162802T1 (de) 1998-02-15

Family

ID=10616392

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88303803T ATE162802T1 (de) 1987-04-27 1988-04-27 Amyloid-peptide

Country Status (8)

Country Link
EP (1) EP0289287B1 (de)
JP (3) JP2766647B2 (de)
AT (1) ATE162802T1 (de)
CA (1) CA1341333C (de)
DE (1) DE3856121T2 (de)
ES (1) ES2114522T3 (de)
GB (1) GB8709871D0 (de)
GR (1) GR3026640T3 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE454299B (sv) * 1986-10-08 1988-04-18 Westermark P Sats innehallande polypeptid som finns i pankreasoamyloid och/eller antikroppar riktade mot polypeptiden
GB8720115D0 (en) * 1987-08-26 1987-09-30 Cooper G J S Treatment of diabetes mellitus
WO1989006135A1 (en) * 1988-01-11 1989-07-13 Amylin Corporation Treatment of type 2 diabetes mellitus
US5405831A (en) * 1989-07-08 1995-04-11 Amylin Pharmaceuticals, Inc. Treatment of bone disorders
JPH04500688A (ja) * 1989-07-10 1992-02-06 アミリン・コーポレイション 肥満および本態性高血圧および関連疾患の治療
US5260275A (en) * 1990-08-14 1993-11-09 Amylin Pharmaceuticals, Inc. Hypoglycemics
EP0503827A1 (de) * 1991-03-15 1992-09-16 Pfizer Inc. Verwendung von Amylin und Calcitonin-Genverwandten Peptiden und Antagonisten davon
AU669110B2 (en) * 1991-05-24 1996-05-30 Amylin Pharmaceuticals, Inc. Amylin and possibly insulin containing composition for the treatment of anorexia and related states
US5858684A (en) * 1991-08-23 1999-01-12 The Brigham And Women's Hospital, Inc. Method of screening calcium receptor-active molecules
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5763569A (en) * 1991-08-23 1998-06-09 The Brigham And Women's Hospital, Inc Calcium receptor-active molecules
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6031003A (en) * 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5688938A (en) * 1991-08-23 1997-11-18 The Brigham & Women's Hospital, Inc. Calcium receptor-active molecules
WO1993019774A1 (en) * 1992-04-03 1993-10-14 Amylin Pharmaceuticals, Inc. Amylin and possibly insulin containing composition for the treatment of anorexia and related states
AU679182B2 (en) * 1992-05-15 1997-06-26 Amylin Pharmaceuticals, Inc. Antibody assay for amylin
US5962314A (en) * 1993-02-23 1999-10-05 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
BR9407424A (pt) * 1993-09-07 1996-04-09 Amylin Pharmaceuticals Inc Métodos para regular motilidade gastrointestinal
DE69535461T2 (de) 1994-10-21 2008-09-25 NPS Pharmaceuticals, Inc., Salt Lake City Kalzium-rezeptor aktive verbindungen
US6110707A (en) * 1996-01-19 2000-08-29 Board Of Regents, The University Of Texas System Recombinant expression of proteins from secretory cell lines
EP0910578A2 (de) * 1996-01-19 1999-04-28 The Board Of Regents, The University Of Texas System Rekombinante expression von proteinen mittels sekretorischer zellinien
EP0907631B1 (de) * 1996-05-01 2003-06-18 Nps Pharmaceuticals, Inc. Verbindungen , die auf anorganische ionen-rezeptoren wirken
DE19725619A1 (de) 1997-06-17 1998-12-24 Fraunhofer Ges Forschung Peptide als Agonisten und/oder Inhibitoren der Amyloidbildung und Zytotoxizität sowie der Verwendung bei Alzheimer'schen Krankheit, beim Typ II Diabetes mellitus und bei spongiformen Encephalopathien
US6821954B2 (en) * 1997-09-18 2004-11-23 Auckland Uniservices Limited Compounds and uses thereof in treating bone disorders
US6087334A (en) * 1998-08-21 2000-07-11 Amylin Pharmaceuticals, Inc. Anti-diabetic peptides
JP2004517050A (ja) * 2000-09-19 2004-06-10 ユニバーシティ オブ トロント Iapp原線維形成の抑制剤およびそれらの使用
WO2004037168A2 (en) 2002-10-18 2004-05-06 Amylin Pharmaceuticals, Inc. Treatment of pancreatitis with amylin
EP2233497A3 (de) 2004-02-11 2011-01-12 Amylin Pharmaceuticals, Inc. Peptide der amylin Familie, Verfahren zu deren Herstellung und Verwendung
WO2005079830A1 (en) * 2004-02-23 2005-09-01 Paul Fraser Inhibitors of amyloid fibril formation and uses thereof
US7399744B2 (en) 2004-03-04 2008-07-15 Amylin Pharmaceuticals, Inc. Methods for affecting body composition
WO2006010533A2 (en) * 2004-07-28 2006-02-02 F. Hoffmann-La Roche Ag Pancreatic polypeptide as target/marker of beta cell failure
CA2584806C (en) 2004-11-01 2014-06-17 Amylin Pharmaceuticals, Inc. Treatment of obesity and related disorders
EP2258382A3 (de) 2005-03-31 2014-05-14 Amylin Pharmaceuticals, LLC Amylin und Amylin-Antagonisten zur Behandlung psychiatrischer Erkrankungen und Störungen
JP5312054B2 (ja) 2006-03-15 2013-10-09 ノボ・ノルデイスク・エー/エス アミリンとインスリンの混合物
EP2504355B1 (de) * 2009-11-25 2015-07-22 Novo Nordisk A/S Verfahren zur herstellung von polypeptiden
CN103308670B (zh) * 2012-03-08 2017-06-09 思芬构技术有限公司 用于预测对象患糖尿病和/或代谢综合征的风险的方法
KR102117969B1 (ko) 2012-09-12 2020-06-04 뉴리뮨 홀딩 아게 인간 섬 아밀로이드 폴리펩티드(hiapp) 특이적 항체 및 이들의 용도
WO2015196174A1 (en) 2014-06-20 2015-12-23 Greene Howard E Infusion delivery devices and methods
CN110467666A (zh) * 2019-09-17 2019-11-19 湖北强耀生物科技有限公司 一种新型胰岛淀粉样多肽的合成方法
TW202144387A (zh) * 2020-02-11 2021-12-01 美商聯合生物醫學公司 針對胰島澱粉樣多肽(iapp)的胜肽免疫原及其預防和治療與聚集iapp相關疾病的製劑
WO2025150507A1 (ja) * 2024-01-12 2025-07-17 学校法人東邦大学 インスリン・アミロイド化重合蛋白質、抗体、抗体産生b細胞および医療用組成物
CN119930779A (zh) * 2025-02-10 2025-05-06 南京工业大学 采用淀粉样蛋白基序调节嵌合蛛丝蛋白亲疏水性的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE500044C2 (sv) * 1985-02-15 1994-03-28 Gambro Lundia Ab Peptidförening, antiserum framställt med användning av denna förening samt användning av föreningen
SE454299B (sv) * 1986-10-08 1988-04-18 Westermark P Sats innehallande polypeptid som finns i pankreasoamyloid och/eller antikroppar riktade mot polypeptiden
GB8720115D0 (en) * 1987-08-26 1987-09-30 Cooper G J S Treatment of diabetes mellitus

Also Published As

Publication number Publication date
EP0289287A3 (de) 1990-05-30
JPH09133679A (ja) 1997-05-20
HK1003033A1 (en) 1998-09-30
ES2114522T3 (es) 1998-06-01
GR3026640T3 (en) 1998-07-31
JP2766647B2 (ja) 1998-06-18
CA1341333C (en) 2002-01-22
JPH10168099A (ja) 1998-06-23
DE3856121D1 (de) 1998-03-05
DE3856121T2 (de) 1998-07-23
EP0289287B1 (de) 1998-01-28
EP0289287A2 (de) 1988-11-02
GB8709871D0 (en) 1987-06-03
JPS6463594A (en) 1989-03-09

Similar Documents

Publication Publication Date Title
ATE162802T1 (de) Amyloid-peptide
EP0208491A3 (en) Hybrid polypeptides and process for their preparation
HUT46638A (en) Process for producing 1,1,1-trifluoro-2,2-dichloroethane in the presence of hydrogen fluoride catalyst
IL62553A0 (en) Vectors comprising dna sequences and methods for producing recombinant dna molecules and cloning vectors
HUT46356A (en) Process for producing the preprotein of apc polypeptide and the dna encoding it, as well as for the diagnostic utilization of the dna and the protein
DE3163867D1 (en) Novel substituted pyrazinyl-1,2,4-oxadiazol-5-ones, a process for preparing same and a pharmaceutical composition containing same
IL70414A (en) Polypeptide having human h2-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors
HUT46061A (en) Dna sequences encoding hirudin-like protein and process for producing such proteins
HUT55801A (en) Process for producing anti-coagulative peptides marked with radioactivity
GB8720901D0 (en) Treating leather
GB8906511D0 (en) Process for producing semi-finished leather goods
DE69233005D1 (de) DNA kodierend für Propylendopeptidase und dessen Verwendung
PH23901A (en) Treatment of diabetes using fluoxetine
HUT47136A (en) Process for producing cyclic peptides with anticoagulant effect
DE3851364D1 (de) Verfahren zur Herstellung von supraleitendem Material.
ZA902054B (en) Production and use of anthelmintic agents and protective immunogens
PT87857A (pt) Process for the preparation of novel immunossupressant peptides
HUT53125A (en) Process for producing peptides with anticoagulant activity
PT73587A (en) Process for preparing novel peptides
EP0281089A3 (en) Process for the preparation of factor viii:c deficient plasma, and deficient plasma obtained therwith
IL89877A0 (en) Process for the preparation of proteins which start with n-terminal proline
ZA832293B (en) Chromophoric peptides,a process for their preparation,agents containing them and their use for determining dd-carboxypeptidases
GB2220215B (en) Process for treating leather
DE3851214D1 (de) Verfahren zur Herstellung von flachen Vorrichtungen zum Pumpen von Sauerstoff.
IT1221857B (it) Per cinturini in pelle per orologi

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time