ES2130686T3 - Procedimiento para la preparacion de metalocenil-fosfinas opticamente activas. - Google Patents
Procedimiento para la preparacion de metalocenil-fosfinas opticamente activas.Info
- Publication number
- ES2130686T3 ES2130686T3 ES95941034T ES95941034T ES2130686T3 ES 2130686 T3 ES2130686 T3 ES 2130686T3 ES 95941034 T ES95941034 T ES 95941034T ES 95941034 T ES95941034 T ES 95941034T ES 2130686 T3 ES2130686 T3 ES 2130686T3
- Authority
- ES
- Spain
- Prior art keywords
- sup
- sub
- optically active
- preparation
- auction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical group [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- -1 METHYL GROUPS Chemical group 0.000 abstract 1
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical group [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 229910052707 ruthenium Inorganic materials 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Abstract
SE DESCRIBE UN NUEVO METODO DE PREPARACION DE METALOCENILFOSFINAS OPTICAMENTE ACTIVAS CON LA FORMULA GENERAL REPRESENTADA. EN LA FORMULA (IA) (IB), M REPRESENTA HIERRO, RUTENIO O NIQUEL; R{SUP,1} Y R{SUP,1''} REPRESENTAN GRUPOS ALQUILO C{SUB,1} - C{SUB,4}; R{SUP,2} Y R{SUP,3} REPRESENTAN INDEPENDIENTEMENTE UNO DE OTRO UN HIDROGENO O UN GRUPO ALQUILO C{SUB,1} - C{SUB,4} O, JUNTO CON EL ATOMO DE NITROGENO, FORMAN UN ANILLO HETEROCICLICO SATURADO DE CINCO O SEIS MIEMBROS, QUE OPCIONALMENTE PUEDE CONTENER OTROS HETEROATOMOS; R{SUP,4} Y R{SUP,5} REPRESENTAN INDEPENDIENTEMENTE UNO DE OTRO UN GRUPO ALQUILO C{SUB,1} - C{SUB,4} (POR EJEMPLO) O UN GRUPO ARILO OPCIONALMENTE SUSTITUIDO CON UNO O MAS GRUPOS METILO O METOXI O CON UNO O MAS ATOMOS DE FLUOR. ESTAS SE OBTIENEN DE ACIL O 1,1'' DIACILMETALOCENOS MEDIANTE REDUCCION ENANTIOSELECTIVA CON BORANO EN PRESENCIA DE OXAZOBOROLIDINAS OPTICAMENTE ACTIVAS, ESTERIFICACION DE LOS ALCANOLES METALOCENILOS ASI OBTENIDOS, SUSTITUCION NUCLEOFILICA DEL GRUPO ESTERCON UNA AMINA SECUNDARIA, LITIACION Y REACCION CON UN HALURO DE FOSFINA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH359894 | 1994-11-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2130686T3 true ES2130686T3 (es) | 1999-07-01 |
Family
ID=4259445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95941034T Expired - Lifetime ES2130686T3 (es) | 1994-11-29 | 1995-11-28 | Procedimiento para la preparacion de metalocenil-fosfinas opticamente activas. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5760264A (es) |
| EP (1) | EP0794957B1 (es) |
| JP (1) | JPH10509968A (es) |
| CN (1) | CN1166835A (es) |
| AT (1) | ATE179178T1 (es) |
| AU (1) | AU4257396A (es) |
| CA (1) | CA2203518A1 (es) |
| CZ (1) | CZ160597A3 (es) |
| DE (1) | DE59505728D1 (es) |
| DK (1) | DK0794957T3 (es) |
| ES (1) | ES2130686T3 (es) |
| FI (1) | FI972262A0 (es) |
| GR (1) | GR3030357T3 (es) |
| HU (1) | HU216288B (es) |
| NO (1) | NO307885B1 (es) |
| PL (1) | PL320698A1 (es) |
| SK (1) | SK64697A3 (es) |
| WO (1) | WO1996016971A1 (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE195525T1 (de) * | 1995-02-24 | 2000-09-15 | Novartis Ag | Silylierte ferrocenyldiphosphine, an anorganische oder polymere organische träger gebundene silylierte ferrocenyldiphosphine sowie metallkomplexe davon, ihre herstellung und verwendung |
| EP0820460B1 (en) * | 1995-04-11 | 1999-07-28 | Novartis AG | Dihalogenated ferrocenes and processes for the preparation thereof |
| PT803510E (pt) * | 1996-04-25 | 2003-01-31 | Hoechst Ag | 1,1'-difosfino-ferrocenos 2,2'-dissubstituidos e 1-fosfino-ferrocenos 1',2-dissubstituidos processo para a sua producao sua utilizacao bem como complexos de metais de transicao contendo-os |
| DE19952348A1 (de) * | 1998-12-19 | 2000-06-21 | Degussa | Liganden und Komplexe zur enantioselektiven Hydrierung |
| EP1223932A4 (en) * | 1999-10-01 | 2003-01-15 | Smithkline Beecham Corp | COMPOUNDS AND METHODS |
| US6590115B2 (en) * | 2000-09-29 | 2003-07-08 | Eastman Chemical Company | Phosphino-aminophosphines |
| US6620954B1 (en) * | 2002-03-25 | 2003-09-16 | Eastman Chemical Company | Phosphinometallocenylamides as novel ligands for asymmetric catalysis |
| JP4218261B2 (ja) * | 2002-06-11 | 2009-02-04 | ダイキン工業株式会社 | ポンプユニット |
| GB0228018D0 (en) * | 2002-11-30 | 2003-01-08 | Lucite Int Uk Ltd | Carbonylation of ester |
| KR100924521B1 (ko) * | 2002-09-12 | 2009-11-02 | 루싸이트 인터내셔날 유케이 리미티드 | 촉매 시스템 |
| DE10242351A1 (de) * | 2002-09-12 | 2004-03-18 | Bayer Ag | Chirale Monophosphorverbindungen und deren Übergangsmetallkomplexe |
| WO2005003070A1 (en) | 2003-07-03 | 2005-01-13 | Lucite International Uk Limited | Process for the hydroformylation of ethylenically unsaturated compounds |
| CA2548925A1 (en) * | 2003-12-12 | 2005-06-23 | Solvias Ag | Method for producing orthometalated and orthosubstituted metallocences |
| GB0403592D0 (en) * | 2004-02-18 | 2004-03-24 | Lucite Int Uk Ltd | A catalyst system |
| GB0411951D0 (en) * | 2004-05-28 | 2004-06-30 | Lucite Int Uk Ltd | Carbonylation of ester |
| GB0516556D0 (en) * | 2005-08-12 | 2005-09-21 | Lucite Int Uk Ltd | Improved catalyst system |
| JP2009515936A (ja) | 2005-11-17 | 2009-04-16 | ルーサイト インターナショナル ユーケー リミテッド | エチレン性不飽和化合物のカルボニル化 |
| CN101421285B (zh) * | 2006-04-12 | 2013-02-06 | 索尔维亚斯股份公司 | 二茂铁二膦 |
| GB0607494D0 (en) | 2006-04-13 | 2006-05-24 | Lucite Int Uk Ltd | Metal complexes |
| JP5208928B2 (ja) * | 2006-06-08 | 2013-06-12 | 上海交通大学 | Ｃ２−対称の面性キラリティーだけをもつルテノセンビスホスフィン配位子及びその合成方法 |
| CN100465181C (zh) * | 2006-06-08 | 2009-03-04 | 上海交通大学 | C2－对称的只具有面手性的二茂钌双膦配体的合成方法 |
| CA2671409C (en) * | 2006-12-02 | 2016-07-26 | Lucite International Uk Limited | Novel carbonylation ligands and their use in the carbonylation of ethylenically unsaturated compounds |
| GB0625518D0 (en) * | 2006-12-21 | 2007-01-31 | Lucite Int Uk Ltd | Carbonylation of conjugated dienes |
| GB0812297D0 (en) * | 2008-07-04 | 2008-08-13 | Lucite Int Uk Ltd | Novel carbonylation ligand sand thier use of in the carbonylation of ethylenically unsaturated compounds |
| GB201000078D0 (en) | 2010-01-05 | 2010-02-17 | Lucite Int Uk Ltd | Process for the carbonylation of ethylenically unsaturated compounds, novel carbonylation ligands and catalyst systems incorporatng such ligands |
| CN103755748A (zh) * | 2013-12-26 | 2014-04-30 | 浙江中山化工集团股份有限公司 | 一种手性的（r）-1-二茂铁基乙基二甲胺的制备工艺 |
| CN106046065B (zh) * | 2016-05-26 | 2018-07-13 | 河南省科学院化学研究所有限公司 | 一种合成c2-对称性手性二茂铁膦化合物的方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4943635A (en) * | 1987-08-27 | 1990-07-24 | President & Fellows Of Harvard College | Enantioselective reduction of ketones |
-
1995
- 1995-11-28 HU HU9800268A patent/HU216288B/hu not_active IP Right Cessation
- 1995-11-28 SK SK646-97A patent/SK64697A3/sk unknown
- 1995-11-28 DE DE59505728T patent/DE59505728D1/de not_active Expired - Fee Related
- 1995-11-28 AU AU42573/96A patent/AU4257396A/en not_active Abandoned
- 1995-11-28 CA CA002203518A patent/CA2203518A1/en not_active Abandoned
- 1995-11-28 AT AT95941034T patent/ATE179178T1/de not_active IP Right Cessation
- 1995-11-28 CZ CZ971605A patent/CZ160597A3/cs unknown
- 1995-11-28 WO PCT/EP1995/004678 patent/WO1996016971A1/de not_active Application Discontinuation
- 1995-11-28 US US08/836,978 patent/US5760264A/en not_active Expired - Fee Related
- 1995-11-28 ES ES95941034T patent/ES2130686T3/es not_active Expired - Lifetime
- 1995-11-28 JP JP8518175A patent/JPH10509968A/ja active Pending
- 1995-11-28 CN CN95196454A patent/CN1166835A/zh active Pending
- 1995-11-28 DK DK95941034T patent/DK0794957T3/da active
- 1995-11-28 EP EP95941034A patent/EP0794957B1/de not_active Expired - Lifetime
- 1995-11-28 PL PL95320698A patent/PL320698A1/xx unknown
-
1997
- 1997-05-28 NO NO972436A patent/NO307885B1/no not_active IP Right Cessation
- 1997-05-28 FI FI972262A patent/FI972262A0/fi unknown
-
1999
- 1999-05-27 GR GR990401449T patent/GR3030357T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT77467A (hu) | 1998-05-28 |
| PL320698A1 (en) | 1997-10-27 |
| NO307885B1 (no) | 2000-06-13 |
| CN1166835A (zh) | 1997-12-03 |
| FI972262A (fi) | 1997-05-28 |
| FI972262A0 (fi) | 1997-05-28 |
| HU216288B (hu) | 1999-06-28 |
| WO1996016971A1 (de) | 1996-06-06 |
| NO972436D0 (no) | 1997-05-28 |
| CZ160597A3 (en) | 1997-10-15 |
| DK0794957T3 (da) | 1999-10-25 |
| US5760264A (en) | 1998-06-02 |
| EP0794957B1 (de) | 1999-04-21 |
| AU4257396A (en) | 1996-06-19 |
| GR3030357T3 (en) | 1999-09-30 |
| SK64697A3 (en) | 1997-11-05 |
| JPH10509968A (ja) | 1998-09-29 |
| ATE179178T1 (de) | 1999-05-15 |
| NO972436L (no) | 1997-05-28 |
| DE59505728D1 (de) | 1999-05-27 |
| CA2203518A1 (en) | 1996-06-06 |
| EP0794957A1 (de) | 1997-09-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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