ES2123934T3 - Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos. - Google Patents

Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos.

Info

Publication number
ES2123934T3
ES2123934T3 ES95402744T ES95402744T ES2123934T3 ES 2123934 T3 ES2123934 T3 ES 2123934T3 ES 95402744 T ES95402744 T ES 95402744T ES 95402744 T ES95402744 T ES 95402744T ES 2123934 T3 ES2123934 T3 ES 2123934T3
Authority
ES
Spain
Prior art keywords
erythromycin
medicines
application
preparation procedure
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95402744T
Other languages
English (en)
Inventor
Constantin Agouridas
Jean-Francois Chantot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel, Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel
Application granted granted Critical
Publication of ES2123934T3 publication Critical patent/ES2123934T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A LOS COMPUESTOS DE FORMULA (I) EN LOS QUE R{SUB,1} ES UN RADICAL HIDROXILO O O-ACILO QUE CONTIENE DE 2 A 20 ATOMOS DE CARBONO, R{SUB,2} ES UN ATOMO DE HIDROGENO O UN RADICAL METILO, R{SUB,3} ES , BIEN UN RADICAL {(CH{SUB,2})}{SUB,M}R{SUB,4} EN EL QUE M ES UN NUMERO ENTERO QUE VARIA DE 1 A 6, BIEN UN RADICAL EN EL QUE N Y P IDENTICOS O DIFERENTES REPRESENTAN UN NUMERO ENTERO QUE VARIA DE 0 A 6, Y BIEN A Y B IDENTICOS O DIFERENTES REPRESENTAN UN ATOMO DE HIDROGENO O UN ATOMO DE HALOGENO O UN RADICAL ALQUILO QUE CONTIENE HASTA 8 ATOMOS DE CARBONO, SIENDO LA GEOMETRIA DE LA DOBLE CONEXION E O Z O UNA MEZCLA DE E + Z O BIEN A Y B FORMAN CON LOS ATOMOS DE CARBONO A LOS QUE ESTAN UNIDOS UN TRIPLE ENLACE, BIEN UN RADICAL -N-{(CH{SUB,2})}{SUB,Q}({SUB,4} EN EL QUE Q REPRESENTA UN NUMERO ENTERO QUE VARIA DE 0 A 6, SIENDO R{SUB,4} UN RADICAL HETEROCICLICO MONO O POLICICLICO EVENTUALMENTE SUSTITUIDO, ASI COMO SUS SALES DE ADICION CON LOS ACIDOS. LOS COMPUESTOS DE FORMULA (I) PRESENTAN INTERESANTES PROPIEDADES ANTIBIOTICAS.
ES95402744T 1994-12-09 1995-12-06 Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos. Expired - Lifetime ES2123934T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9414807A FR2727969B1 (fr) 1994-12-09 1994-12-09 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ES2123934T3 true ES2123934T3 (es) 1999-01-16

Family

ID=9469625

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95402744T Expired - Lifetime ES2123934T3 (es) 1994-12-09 1995-12-06 Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicacion como medicamentos.

Country Status (14)

Country Link
US (1) US5786339A (es)
EP (1) EP0716093B1 (es)
JP (1) JP4083824B2 (es)
KR (1) KR100371473B1 (es)
CN (1) CN1067077C (es)
AT (1) ATE172467T1 (es)
AU (1) AU697876B2 (es)
CA (1) CA2164798C (es)
DE (1) DE69505487T2 (es)
DK (1) DK0716093T3 (es)
ES (1) ES2123934T3 (es)
FR (1) FR2727969B1 (es)
HU (1) HU215192B (es)
ZA (1) ZA9510447B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2745290B1 (fr) * 1996-02-28 1998-04-03 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
USRE38520E1 (en) * 1996-02-28 2004-05-18 Aventis Pharma S.A. Erythromycin derivatives, method for preparing same, and use thereof as drugs
DE19652362A1 (de) 1996-12-17 1998-06-18 Thomson Brandt Gmbh Verfahren und Vorrichtung zur Kompensation der durch die Verarbeitung von Chrominanz-Signalen entstehenden Luminanzdefekte
US5955440A (en) * 1998-03-27 1999-09-21 Abbott Laboratories Macrolide LHRH antagonists
US5972898A (en) * 1998-03-27 1999-10-26 Abbott Laboratories 3',3-N-bis-substituted macrolide LHRH antagonists
US6020521A (en) * 1998-08-26 2000-02-01 Abbott Laboratories Macrolide LHRH antagonists
US6387885B1 (en) * 1998-08-26 2002-05-14 Abbott Laboratories 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl erythromycin derivatives as LHRH antagonists
ES2243066T3 (es) 1998-09-22 2005-11-16 Pfizer Products Inc. Antibioticos de carbamato y carbazato cetolida.
FR2785612A1 (fr) * 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
ATE344269T1 (de) 1998-12-10 2006-11-15 Pfizer Prod Inc Carbamat und carbazat ketolid antibiotika
BR9916969A (pt) * 1999-01-27 2001-11-06 Pfizer Prod Inc Antibióticos cetólidos
WO2000071557A1 (en) * 1999-05-24 2000-11-30 Pfizer Products Inc. 13-methyl-erythromycin derivatives
AU6316400A (en) * 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO2001010880A1 (fr) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
WO2001010878A1 (fr) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
ID27331A (id) * 1999-09-29 2001-03-29 Pfizer Prod Inc Pembuatan antibiotik-antibiotik ketolida karbamat
TWI283577B (en) * 1999-10-11 2007-07-11 Sod Conseils Rech Applic Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
WO2005007143A2 (en) * 2003-07-14 2005-01-27 The Board Of Trustees Of The University Of Illinois Use of makrolides and ketolides for the treatment of tuberculosis
JP2008508322A (ja) * 2004-07-28 2008-03-21 ランバクシー ラボラトリーズ リミテッド 抗菌剤としてのケトライド誘導体
EP1836211B1 (en) * 2004-12-21 2010-03-03 Pfizer Products Inc. Macrolides
US10130465B2 (en) 2016-02-23 2018-11-20 Abbott Cardiovascular Systems Inc. Bifurcated tubular graft for treating tricuspid regurgitation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
JPH07219312A (ja) * 1993-12-10 1995-08-18 Canon Inc 画像形成装置

Also Published As

Publication number Publication date
HUT74075A (en) 1996-10-28
JPH08231583A (ja) 1996-09-10
DK0716093T3 (da) 1999-06-28
DE69505487D1 (de) 1998-11-26
KR100371473B1 (ko) 2003-07-22
FR2727969A1 (fr) 1996-06-14
CA2164798A1 (fr) 1996-06-10
FR2727969B1 (fr) 1997-01-17
ATE172467T1 (de) 1998-11-15
US5786339A (en) 1998-07-28
HU215192B (hu) 1998-10-28
JP4083824B2 (ja) 2008-04-30
CA2164798C (fr) 2007-03-20
AU4032495A (en) 1996-06-20
ZA9510447B (en) 1996-12-09
CN1067077C (zh) 2001-06-13
DE69505487T2 (de) 1999-05-12
AU697876B2 (en) 1998-10-22
KR960022553A (ko) 1996-07-18
EP0716093B1 (fr) 1998-10-21
CN1133291A (zh) 1996-10-16
EP0716093A1 (fr) 1996-06-12
HU9503524D0 (en) 1996-02-28

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