ES2112845T3 - Derivados de la morfolinurea. - Google Patents

Derivados de la morfolinurea.

Info

Publication number
ES2112845T3
ES2112845T3 ES91108430T ES91108430T ES2112845T3 ES 2112845 T3 ES2112845 T3 ES 2112845T3 ES 91108430 T ES91108430 T ES 91108430T ES 91108430 T ES91108430 T ES 91108430T ES 2112845 T3 ES2112845 T3 ES 2112845T3
Authority
ES
Spain
Prior art keywords
substd
opt
alkyl
alkenyl
morpholineurea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91108430T
Other languages
English (en)
Spanish (es)
Inventor
Klaus Dr Stroech
Bernd-Wieland Dr Kruger
Peter Dr Hoever
Gunther Dr Nentwig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2112845T3 publication Critical patent/ES2112845T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205Radicals derived from carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Pest Control & Pesticides (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES91108430T 1990-06-06 1991-05-24 Derivados de la morfolinurea. Expired - Lifetime ES2112845T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4018070A DE4018070A1 (de) 1990-06-06 1990-06-06 Morpholinoharnstoff-derivate

Publications (1)

Publication Number Publication Date
ES2112845T3 true ES2112845T3 (es) 1998-04-16

Family

ID=6407857

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91108430T Expired - Lifetime ES2112845T3 (es) 1990-06-06 1991-05-24 Derivados de la morfolinurea.

Country Status (18)

Country Link
US (1) US5218002A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0467045B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH04235978A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR920000741A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE163644T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU644438B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR9102322A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2043797A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE4018070A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EG (1) EG19884A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2112845T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU216891B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL98340A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ238351A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT97800B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TR (1) TR26723A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW198028B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA914278B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4302860A1 (de) * 1993-01-22 1994-08-04 Chemie Linz Deutschland N-Cyclische und N,N'dicyclische Harnstoffe
AT400566B (de) * 1993-01-22 1996-01-25 Chemie Linz Gmbh Verwendung und verfahren zur herstellung von n-cyclischen und n,n'-dicyclischen harnstoffen
US6015570A (en) * 1993-12-23 2000-01-18 Tucci Associates, Inc. Slow-release insect-repellent compositions and uses
WO1995017091A1 (en) * 1993-12-23 1995-06-29 Tucci Associates, Inc. Slow-release insect-repellent formulations and uses
AU713171B2 (en) * 1996-06-29 1999-11-25 Samjin Pharmaceutical Co., Ltd. Piperazine derivatives and process for the preparation thereof
AU753691B2 (en) * 1998-06-18 2002-10-24 Novartis Ag Benzazole compounds and their use
DE10032877A1 (de) * 2000-07-06 2002-02-07 Bayer Ag Anthelmintika zur Verhinderung von parasitären Infektionen bei Mensch und Tier III
EP1807078A1 (en) * 2004-10-07 2007-07-18 Vitae Pharmaceuticals, Inc. Diaminoalkane aspartic protease inhibitors
TWI411607B (zh) * 2005-11-14 2013-10-11 Vitae Pharmaceuticals Inc 天門冬胺酸蛋白酶抑制劑
ATE520690T1 (de) * 2006-09-18 2011-09-15 Vitae Pharmaceuticals Inc Piperidinderivate als renin-inhibitoren
CL2007002689A1 (es) 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
US20100317697A1 (en) * 2007-06-20 2010-12-16 Baldwin John J Renin Inhibitors
EP2170815A2 (en) * 2007-06-20 2010-04-07 Vitae Pharmaceuticals, Inc. Renin inhibitors
US8741874B2 (en) * 2007-11-07 2014-06-03 Bayer Cropscience Lp Insecticidal compositions with disinfectant
US20110160300A1 (en) * 2008-06-20 2011-06-30 Marlys Hammond Renin Inhibitors and Methods of Use Thereof
CA2729052A1 (en) * 2008-06-26 2009-12-30 Vitae Pharmaceuticals, Inc. Salts of methyl 2-((r)-(3-chlorophenyl)((r)-1-((s)-2-(methylamino)-3((r)-tetrahydro-2h-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate
AR077692A1 (es) * 2009-08-06 2011-09-14 Vitae Pharmaceuticals Inc Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo
WO2012104865A1 (en) * 2011-01-28 2012-08-09 Director General, Defence Research & Development Organisation (Drdo) N, n- dialkyl -morpholin- 4 - carboxamide compounds as insect repelling agents and a process for their preparation
WO2013065059A1 (en) * 2011-11-04 2013-05-10 Director General, Defence Research & Development Organisation Process for preparation of n,n-di substituted carboxamides
GB201603581D0 (en) 2016-03-01 2016-04-13 Spts Technologies Ltd Plasma processing apparatus

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3161676A (en) * 1962-05-21 1964-12-15 Berkeley Chemical Corp Preparation of substituted alkyl ureas
US3296306A (en) * 1965-03-04 1967-01-03 Upjohn Co Process for 2, 2-diaryl-nu-substituted acetamides
FR2050522A5 (en) * 1969-06-17 1971-04-02 Aries Robert Pesticidal carbamoyl morpholines
DE2206366C3 (de) * 1971-02-16 1980-10-23 Ciba-Geigy Ag, Basel (Schweiz) Verfahren zur Herstellung von substituierten Diaminocarbonylderivaten
US4025652A (en) * 1975-03-31 1977-05-24 William H. Rorer, Inc. Amidinoureas
US4052385A (en) * 1975-10-21 1977-10-04 The Dow Chemical Company Certain n-(2-hydroxyethyl)heteroiminocarboxamides
US4400512A (en) * 1976-12-17 1983-08-23 Rohm And Haas Company Azaspiro compounds
US4356180A (en) * 1979-02-02 1982-10-26 The United States Of America As Represented By The Secretary Of Agriculture Insect repellants
US4389401A (en) * 1979-07-10 1983-06-21 Rohm And Haas Company Arthropod repellents
ATE19510T1 (de) * 1981-12-17 1986-05-15 Haessle Ab Para-substituierte 3-phenoxy-1carbonylaminoalkylaminopropan-2-ole mit blockierenden wirkungen bei betarezeptoren.
DE3314435A1 (de) * 1983-04-21 1984-10-25 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 1,1-disubstituierten thioharnstoffen
JPS61215381A (ja) * 1985-03-22 1986-09-25 Ube Ind Ltd ベンゾオキサジン誘導体および除草剤
DE3539994A1 (de) * 1985-11-12 1987-05-14 Bayer Ag Herbizide mittel enthaltend photosynthesehemmer-herbizide in kombination mit harnstoffderivaten

Also Published As

Publication number Publication date
DE4018070A1 (de) 1991-12-12
IL98340A0 (en) 1992-07-15
TW198028B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-01-11
BR9102322A (pt) 1992-01-07
EP0467045A2 (de) 1992-01-22
PT97800B (pt) 1998-10-30
NZ238351A (en) 1992-06-25
EG19884A (en) 1996-10-31
HU216891B (hu) 1999-10-28
US5218002A (en) 1993-06-08
TR26723A (tr) 1995-05-15
JPH04235978A (ja) 1992-08-25
ATE163644T1 (de) 1998-03-15
EP0467045B1 (de) 1998-03-04
AU644438B2 (en) 1993-12-09
HUT57548A (en) 1991-12-30
KR920000741A (ko) 1992-01-29
DE59108943D1 (de) 1998-04-09
CA2043797A1 (en) 1991-12-07
AU7806491A (en) 1991-12-12
EP0467045A3 (en) 1992-02-05
PT97800A (pt) 1992-03-31
ZA914278B (en) 1992-03-25

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