ATE31307T1 - Benzofuran- und benzopyrancarboxamid-derivate. - Google Patents

Benzofuran- und benzopyrancarboxamid-derivate.

Info

Publication number
ATE31307T1
ATE31307T1 AT84103843T AT84103843T ATE31307T1 AT E31307 T1 ATE31307 T1 AT E31307T1 AT 84103843 T AT84103843 T AT 84103843T AT 84103843 T AT84103843 T AT 84103843T AT E31307 T1 ATE31307 T1 AT E31307T1
Authority
AT
Austria
Prior art keywords
lower alkyl
group
alkyl group
hydrogen atom
image
Prior art date
Application number
AT84103843T
Other languages
English (en)
Inventor
Tetsuya Tahara
Kiyoharu Hayano
Takemi Fukuda
Michihide Setoguchi
Original Assignee
Yoshitomi Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical filed Critical Yoshitomi Pharmaceutical
Application granted granted Critical
Publication of ATE31307T1 publication Critical patent/ATE31307T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT84103843T 1983-04-08 1984-04-06 Benzofuran- und benzopyrancarboxamid-derivate. ATE31307T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58062554A JPS59186969A (ja) 1983-04-08 1983-04-08 ベンゾフラン−およびベンゾピランカルボキサミド誘導体
EP84103843A EP0124783B1 (de) 1983-04-08 1984-04-06 Benzofuran- und Benzopyrancarboxamid-Derivate

Publications (1)

Publication Number Publication Date
ATE31307T1 true ATE31307T1 (de) 1987-12-15

Family

ID=13203591

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84103843T ATE31307T1 (de) 1983-04-08 1984-04-06 Benzofuran- und benzopyrancarboxamid-derivate.

Country Status (8)

Country Link
US (1) US4617314A (de)
EP (1) EP0124783B1 (de)
JP (1) JPS59186969A (de)
KR (1) KR910002883B1 (de)
AT (1) ATE31307T1 (de)
CA (1) CA1238906A (de)
DE (1) DE3468024D1 (de)
ES (1) ES8507135A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888353A (en) * 1986-02-28 1989-12-19 Erbamont, Inc. Carboxamides useful as antiemetic or antipsychotic agents
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents
US5122528A (en) * 1983-12-22 1992-06-16 Erbamont, Inc. Analgesic use of benzobicyclic carboxamides
US5175173A (en) * 1983-12-22 1992-12-29 Sun Jung Hui Carboxamides useful as antiemetic or antipsychotic agents
SE8503055D0 (sv) * 1985-06-19 1985-06-19 Astra Laekemedel Ab Piperonylcarboxamido derivatives
FR2593504B1 (fr) * 1986-01-30 1988-12-09 Ile De France Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques
JPS62234083A (ja) * 1986-02-28 1987-10-14 アーバモント　インク　ディビーエイ　アドリヤ　ラボラトリーズ 鎮吐薬または精神病治療薬として有用なカルボキサミド類
US4772459A (en) * 1986-09-09 1988-09-20 Erbamont, Inc. Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein
DE3724756A1 (de) * 1987-07-25 1989-02-09 Basf Ag Basisch substituierte benzofurancarbonsaeureamide, verfahren zu ihrer herstellung und sie enthaltende therapeutische mittel
EP0314483A1 (de) * 1987-10-29 1989-05-03 Erbamont, Inc. Herstellung von Benzamiden
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
US5122361A (en) * 1989-04-17 1992-06-16 Trustees Of The University Of Pennsylvania Dopamine receptor ligands and imaging agents
GB9005014D0 (en) * 1990-03-06 1990-05-02 Janssen Pharmaceutica Nv N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
NZ246915A (en) * 1992-02-06 1996-05-28 Smithkline Beecham Plc Benzopyran, benzothiopyran and benzofuran derivatives, preparation and pharmaceutical compositions thereof
FR2699533A1 (fr) * 1992-12-21 1994-06-24 Mouhtaram Mohamed Dérivés de N-((1,4-dialkyl-6-arylpipérazine-2-yl)méthyl)benzamides. (Isomères cis et trans) Propriétés pharmacologiques et applications.
GB9317987D0 (en) * 1993-08-26 1993-10-13 Glaxo Group Ltd Chemical compounds
CA2350903A1 (en) * 1998-11-20 2000-06-02 F. Hoffmann-La Roche Ag Pyrrolidine derivatives-ccr-3 receptor antagonists
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US7728155B2 (en) 2003-10-24 2010-06-01 Wyeth Llc Dihydrobenzofuranyl alkanamines and methods for using same as cns agents
MX2007012882A (es) * 2005-04-22 2007-12-10 Wyeth Corp Nuevas combinaciones terapeuticas para el tratamiento o prevencion de la depresion.
CN101287411B (zh) 2005-04-28 2013-03-06 普罗秋斯生物医学公司 药物信息系统及其用途
EP2063905B1 (de) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Behandlungen von lebererkrankungen durch verabreichung von konjugaten aus rezeptor-assoziierten proteinen
PT3395372T (pt) 2009-02-20 2022-05-05 Enhanx Biopharm Inc Sistema de entrega de medicamentos à base de glutationa
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN103908548A (zh) * 2014-04-02 2014-07-09 郭卫杰 一种用于治疗躁狂抑郁性精神病的中药及其制备方法
US20180305334A1 (en) * 2015-10-14 2018-10-25 Aquinnah Pharmaceuticals, Inc. Compounds, compositions and methods of use against stress granules

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL281394A (de) * 1961-07-25
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
MC807A1 (fr) * 1968-07-29 1970-07-30 Soc Et Scient Et Ind De L Ile Procédé de préparation de 3-alcoxy-thianaphtene-carboxamide substituées ou non
US3860619A (en) * 1969-05-09 1975-01-14 Novo Terapeutisk Labor As Sulphonylurea derivatives
GB1358684A (en) * 1970-06-15 1974-07-03 Novo Terapeutisk Labor As Carboxylic acids
DE2152230A1 (de) * 1971-10-20 1973-04-26 Boehringer Mannheim Gmbh Blutzuckersenkende sulfonylaminopyrimidine und verfahren zu deren herstellung
US3953462A (en) * 1973-10-29 1976-04-27 Xeerox Corporation Imaging process
US4205080A (en) * 1977-07-21 1980-05-27 Shell Oil Company 2,3-Dihydro benzofuran carboxamides
EP0108986A1 (de) * 1982-11-02 1984-05-23 Hokuriku Pharmaceutical Co.,Ltd N-substituierte Flavon-8-karbonsäure-amide

Also Published As

Publication number Publication date
DE3468024D1 (de) 1988-01-21
KR910002883B1 (ko) 1991-05-09
JPS6119630B2 (de) 1986-05-17
JPS59186969A (ja) 1984-10-23
KR840009092A (ko) 1984-12-24
ES531121A0 (es) 1985-09-01
CA1238906A (en) 1988-07-05
EP0124783A1 (de) 1984-11-14
US4617314A (en) 1986-10-14
EP0124783B1 (de) 1987-12-09
ES8507135A1 (es) 1985-09-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee