ES2112597T3 - Nuevos derivados de 17-(3-imino-2-alquil-propenil)-5beta,14beta-androstano activos sobre el sistema cardiovascular, procesos para su preparacion y composiciones farmaceuticas que contienen los mismos. - Google Patents

Nuevos derivados de 17-(3-imino-2-alquil-propenil)-5beta,14beta-androstano activos sobre el sistema cardiovascular, procesos para su preparacion y composiciones farmaceuticas que contienen los mismos.

Info

Publication number
ES2112597T3
ES2112597T3 ES95117347T ES95117347T ES2112597T3 ES 2112597 T3 ES2112597 T3 ES 2112597T3 ES 95117347 T ES95117347 T ES 95117347T ES 95117347 T ES95117347 T ES 95117347T ES 2112597 T3 ES2112597 T3 ES 2112597T3
Authority
ES
Spain
Prior art keywords
imino
pharmaceutical compositions
propenil
androstano
14beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95117347T
Other languages
English (en)
Spanish (es)
Inventor
Alberto Cerri
Giuseppe Bianchi
Patrizia Ferrari
Piero Melloni
Maria L Quadri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Application granted granted Critical
Publication of ES2112597T3 publication Critical patent/ES2112597T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
ES95117347T 1994-11-29 1995-11-03 Nuevos derivados de 17-(3-imino-2-alquil-propenil)-5beta,14beta-androstano activos sobre el sistema cardiovascular, procesos para su preparacion y composiciones farmaceuticas que contienen los mismos. Expired - Lifetime ES2112597T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4442486A DE4442486A1 (de) 1994-11-29 1994-11-29 Neue 17-(3-Imino-2-alkylpropylen)-5ß,14ß-androstan-Derivate, die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ES2112597T3 true ES2112597T3 (es) 1998-04-01

Family

ID=6534459

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95117347T Expired - Lifetime ES2112597T3 (es) 1994-11-29 1995-11-03 Nuevos derivados de 17-(3-imino-2-alquil-propenil)-5beta,14beta-androstano activos sobre el sistema cardiovascular, procesos para su preparacion y composiciones farmaceuticas que contienen los mismos.

Country Status (9)

Country Link
US (1) US5705662A (enExample)
EP (1) EP0714908B1 (enExample)
JP (1) JP3899136B2 (enExample)
AT (1) ATE163424T1 (enExample)
CA (1) CA2163935C (enExample)
DE (2) DE4442486A1 (enExample)
DK (1) DK0714908T3 (enExample)
ES (1) ES2112597T3 (enExample)
HK (1) HK1009334A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
US6764817B1 (en) * 1999-04-20 2004-07-20 Target Discovery, Inc. Methods for conducting metabolic analyses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4222404C1 (de) * 1992-07-08 1993-12-02 Sigma Tau Ind Farmaceuti Verwendung von Iminoderivaten von Etianaldehyd zur Behandlung von Hypertonie
DE4227605C2 (de) * 1992-08-20 1995-02-16 Sigma Tau Ind Farmaceuti 17-Hydroxyiminomethyl-14beta-hydroxy-5ß-androstan-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die dieselben enthalten
DE4344236A1 (de) * 1993-12-23 1995-06-29 Sigma Tau Ind Farmaceuti Neue 17-Iminomethylalkenyl-5beta,14beta-androstan- und 17-Iminoalkyl-5beta,14beta-androstan-Derivate , die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
DE4420501A1 (de) * 1994-06-13 1995-12-14 Sigma Tau Ind Farmaceuti Neue Hydrazino- und Hydroxyamino-14beta-hydroxyandrostanderivate mit Aktivität für das cardiovaskuläre System, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die diese enthalten

Also Published As

Publication number Publication date
DK0714908T3 (da) 1998-09-28
DE4442486A1 (de) 1996-05-30
JP3899136B2 (ja) 2007-03-28
CA2163935C (en) 2007-03-06
DE69501660D1 (de) 1998-04-02
CA2163935A1 (en) 1996-05-30
HK1009334A1 (en) 1999-05-28
EP0714908B1 (en) 1998-02-25
EP0714908A2 (en) 1996-06-05
ATE163424T1 (de) 1998-03-15
JPH08225591A (ja) 1996-09-03
DE69501660T2 (de) 1998-07-09
EP0714908A3 (enExample) 1996-06-19
US5705662A (en) 1998-01-06

Similar Documents

Publication Publication Date Title
FI942075A0 (fi) Sappihappojohdannaisten tetratsolijohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkeaineina
DE69104991D1 (de) Mometason-furoate-monohydrat, verfahren zu seiner herstellung und das enthaltende pharmazeutische zusammensetzungen.
DE3761562D1 (de) Taxal-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.
BR9810592A (pt) Composto, processos para preparar um composto, para tratar ou prevenir doenças do sistema endócrino e para a fabricação de um medicamento, composição farmacêutica, e, uso de um composto
MX9704777A (es) Compuestos espiro tetraciclicos, procedimiento para su preparacion y composiciones que los contienen.
ATE104271T1 (de) 2-(2-hydroxy-3phenoxypropylamino)ethylphenoxyacetamide, verfahren und zwischenprodukte zu deren herstellung.
ES2128519T3 (es) Nuevas pirido-tiadiazinas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
IT1229570B (it) Derivati fluorurati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
SE9804212D0 (sv) Compounds
UA48958C2 (uk) 9-o-оксимові похідні еритроміцину а та фармацевтична композиція на їх основі
ES2116612T3 (es) Nuevas bis-naftalimidas para el tratamiento del cancer.
ATE172976T1 (de) 3-aminochroman-spiroderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE69710909D1 (de) Substituierte tetrahydropyridinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
ES2112597T3 (es) Nuevos derivados de 17-(3-imino-2-alquil-propenil)-5beta,14beta-androstano activos sobre el sistema cardiovascular, procesos para su preparacion y composiciones farmaceuticas que contienen los mismos.
RU94000064A (ru) Новые 2-циано-3-гидроксипропенамиды, метод их получения и содержащие их фармацевтические композиции
ES2105815T3 (es) Nuevos derivados de hidrazino- e hidroxiamino-14beta-hidroxiandrostano activos sobre el sistema cardiovascular, procesos para su preparacion y composiciones farmaceuticas que contienen los mismos.
BR0000901A (pt) Derivados 4-fenil-4-heteroarilpiperidina
ES2164454T3 (es) Nuevos compuestos derivados de acido alquilendiamina di o tri-acetico, su procedimiento de preparacion, su utilizacion en composiciones cosmeticas y farmaceuticas y composiciones que los contienen.
ES2145541T3 (es) Nuevos seco-d-esteroides activos sobre el sistema cardiovascular, procedimientos para su preparacion y composiciones farmaceuticas que los contienen.
NO903291D0 (no) Renin-hemmende aminooligohydroksy-derivater.
DE69222143D1 (de) Indanderivate
ATE28647T1 (de) Chinazolinonderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln.
ITMI920082A1 (it) Derivati solforati di acidi biliari
MX9203900A (es) Composicion farmaceutica que comprende derivados de acido benzimidazolin-2-oxo-1-carboxilico.
ES2095542T3 (es) Nuevos ciclopentanperhidrofenantren-17beta-(hidroxi o alcoxi)-17alfa-(aril o heterociclil)-3beta-derivados activos sobre el sistema cardiovascular, procesos para su preparacion y composiciones farmaceuticas que contienen los mismos.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 714908

Country of ref document: ES