ES2110731T3 - Dispositivo para el manejo, el tratamiento y la observacion de particulas pequeñas, especialmente de particulas biologicas. - Google Patents

Dispositivo para el manejo, el tratamiento y la observacion de particulas pequeñas, especialmente de particulas biologicas.

Info

Publication number
ES2110731T3
ES2110731T3 ES94905056T ES94905056T ES2110731T3 ES 2110731 T3 ES2110731 T3 ES 2110731T3 ES 94905056 T ES94905056 T ES 94905056T ES 94905056 T ES94905056 T ES 94905056T ES 2110731 T3 ES2110731 T3 ES 2110731T3
Authority
ES
Spain
Prior art keywords
particles
observation
focused
pct
object holder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94905056T
Other languages
English (en)
Inventor
Raimund Schutze
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2110731T3 publication Critical patent/ES2110731T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H3/00—Production or acceleration of neutral particle beams, e.g. molecular or atomic beams
    • H05H3/04—Acceleration by electromagnetic wave pressure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/10—Scanning
    • G01N2201/103—Scanning by mechanical motion of stage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/10—Scanning
    • G01N2201/108—Miscellaneous
    • G01N2201/1087—Focussed scan beam, e.g. laser

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Sustainable Development (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electromagnetism (AREA)
  • Plasma & Fusion (AREA)
  • Microscoopes, Condenser (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

SE DA A CONOCER UN DISPOSITIVO PARA EL MANEJO, TRATAMIENTO Y OBSERVACION DE PARTICULAS PEQUEÑAS, EN PARTICULAR PARTICULAS BIOLOGICAS. UN PRIMER LASER (4) GENERA RAYOS DE LUZ EN UN PRIMER CAMPO DE LONGITUD DE ONDA QUE ESTA FOCALIZADO POR MEDIO DE UN DISPOSITIVO (12,13;14,15) OPTICO Y FORMA UNA TRAMPA OPTICA. UN SOPORTE (22) DE OBJETO SIRVE PARA LA RECEPCION DE LAS PARTICULAS. SE DISPONE TAMBIEN DE UNA FUENTE DE LUZ PARA PROPOSITOS DE OBSERVACION ASI COMO DISPOSITIVOS DE GRABADO Y DE OBSERVACION PARA EL PROCESO DE OBSERVADO Y REGISTRO DE LAS PARTICULAS Y SU COMPORTAMIENTO. UN SEGUNDO LASER (3) GENERA RAYOS DE LUZ EN UN SEGUNDO CAMPO DE LONGITUD DE ONDA QUE SE FOCALIZAN SOBRE LAS PARTICULAS EN EL LADO EN QUE PUEDEN SER TRATADAS. LOS DISPOSITIVOS OPTICOS PARA LOS RAYOS DE LUZ PUEDEN SER POSICIONADOS Y AJUSTADOS DE FORMA INDEPENDIENTE UNO DE OTRO Y DE ESTA FORMA LOS RAYOS DE LUZ PUEDEN SER FOCALIZADOS EN EL MISMO PLANO DEL OBJETO O CON DESPLAZAMIENTO EN EL PRINCIPIO DE TRATAMIENTO Y CON OBSERVACION DE FORMA INDEPENDIENTE DE SUS LONGITUDES DE ONDA.
ES94905056T 1993-01-13 1994-01-13 Dispositivo para el manejo, el tratamiento y la observacion de particulas pequeñas, especialmente de particulas biologicas. Expired - Lifetime ES2110731T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4300698A DE4300698A1 (de) 1993-01-13 1993-01-13 Vorrichtung und Verfahren zur Handhabung, Bearbeitung und Beobachtung kleiner Teilchen, insbesondere biologischer Teilchen

Publications (1)

Publication Number Publication Date
ES2110731T3 true ES2110731T3 (es) 1998-02-16

Family

ID=6478110

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94905056T Expired - Lifetime ES2110731T3 (es) 1993-01-13 1994-01-13 Dispositivo para el manejo, el tratamiento y la observacion de particulas pequeñas, especialmente de particulas biologicas.

Country Status (13)

Country Link
US (1) US5689109A (es)
EP (1) EP0679325B1 (es)
JP (1) JPH08505955A (es)
KR (1) KR960700625A (es)
AT (1) ATE159404T1 (es)
BR (1) BR9405806A (es)
CA (1) CA2153167A1 (es)
DE (2) DE4300698A1 (es)
DK (1) DK0679325T3 (es)
ES (1) ES2110731T3 (es)
RU (1) RU2120614C1 (es)
SG (1) SG46367A1 (es)
WO (1) WO1994016543A1 (es)

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US5952651A (en) * 1996-06-10 1999-09-14 Moritex Corporation Laser manipulation apparatus and cell plate used therefor
KR100241286B1 (ko) * 1996-09-23 2000-02-01 구본준 액정표시소자
WO1998028623A1 (en) 1996-12-20 1998-07-02 Gamera Bioscience Corporation An affinity binding-based system for detecting particulates in a fluid
DE19719344A1 (de) * 1997-05-07 1998-11-12 Univ Schiller Jena Anordnung zur optischen Mikromanipulation, Analyse und Bearbeitung von Objekten
US6055106A (en) * 1998-02-03 2000-04-25 Arch Development Corporation Apparatus for applying optical gradient forces
US6067859A (en) * 1999-03-04 2000-05-30 The Board Of Regents, The University Of Texas System Optical stretcher
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DE10018255C2 (de) * 2000-04-13 2003-08-28 Leica Microsystems Laserschneid-Verfahren und Laserschneid-Vorrichtung zum Laserschneiden mit mikroskopischer Proben
DE10018251C2 (de) 2000-04-13 2003-08-14 Leica Microsystems Laserschneid-Vorrichtung mit Mikroskop
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US20030007894A1 (en) 2001-04-27 2003-01-09 Genoptix Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles
US6778724B2 (en) 2000-11-28 2004-08-17 The Regents Of The University Of California Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices
CN1854778A (zh) 2001-06-20 2006-11-01 阿尔利克斯公司 光开关和光路由器以及光滤波器
US6734436B2 (en) 2001-08-07 2004-05-11 Sri International Optical microfluidic devices and methods
US7699767B2 (en) 2002-07-31 2010-04-20 Arryx, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
CN103364326B (zh) * 2002-07-31 2017-05-03 阿尔利克斯公司 利用全息激光控制分类物质的系统和方法
US11243494B2 (en) 2002-07-31 2022-02-08 Abs Global, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US7150834B2 (en) 2003-07-31 2006-12-19 Arryx, Inc. Multiple laminar flow-based rate zonal or isopycnic separation with holographic optical trapping of blood cells and other static components
US20080316575A1 (en) * 2002-08-01 2008-12-25 The University Of Chicago., Aberration correction of optical traps
US7745221B2 (en) 2003-08-28 2010-06-29 Celula, Inc. Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network
DE10347326B4 (de) 2003-10-11 2022-08-04 Leica Microsystems Cms Gmbh Anordnung mit einem Mikroskop und einem Modul
US6943062B2 (en) * 2003-10-20 2005-09-13 Taiwan Semiconductor Manufacturing Co., Ltd. Contaminant particle removal by optical tweezers
JP2005335020A (ja) * 2004-05-27 2005-12-08 Nano Photonics Kenkyusho:Kk 微小物体加工装置
DE102004034961A1 (de) * 2004-07-16 2006-02-02 Carl Zeiss Jena Gmbh Lichtrastermikroskop mit linienförmiger Abtastung und Verwendung
DE102004034987A1 (de) * 2004-07-16 2006-02-02 Carl Zeiss Jena Gmbh Lichtrastermikroskop und Verwendung
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US7460240B2 (en) * 2005-10-17 2008-12-02 Arryx, Inc. Apparatus and method for detecting deformability of cells using spatially modulated optical force microscopy
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EP2047479A2 (en) * 2006-07-26 2009-04-15 Ecole Polytechnique Federale De Lausanne (Epfl) Miniaturized optical tweezers based on high-na micro-mirrors
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JP4389991B2 (ja) * 2007-10-26 2009-12-24 ソニー株式会社 微小粒子の光学的測定方法及び光学的測定装置
JP2011516914A (ja) * 2008-04-03 2011-05-26 カール ゼイス エスエムエス リミテッド 液体中の気泡の形成、捕獲および操作方法
US10908066B2 (en) 2010-11-16 2021-02-02 1087 Systems, Inc. Use of vibrational spectroscopy for microfluidic liquid measurement
CN103575624A (zh) * 2012-08-06 2014-02-12 金济远 光学粒子测量装置
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JP2018509615A (ja) 2015-02-19 2018-04-05 プレミアム ジェネティクス （ユーケー） リミテッド 走査型赤外線測定システム
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RU167405U1 (ru) * 2016-06-08 2017-01-10 Федеральное государственное бюджетное образовательное учреждение высшего образования "Сибирский государственный университет геосистем и технологий" (СГУГиТ) Мезомасштабная оптическая ловушка в поле стоячей волны на основе двух встречных пучков
US10539776B2 (en) 2017-10-31 2020-01-21 Samantree Medical Sa Imaging systems with micro optical element arrays and methods of specimen imaging
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Also Published As

Publication number Publication date
RU2120614C1 (ru) 1998-10-20
SG46367A1 (en) 1998-02-20
DK0679325T3 (da) 1997-12-08
EP0679325B1 (de) 1997-10-15
WO1994016543A1 (de) 1994-07-21
AU671900B2 (en) 1996-09-12
DE4300698A1 (de) 1994-07-14
JPH08505955A (ja) 1996-06-25
BR9405806A (pt) 1995-12-19
EP0679325A1 (de) 1995-11-02
US5689109A (en) 1997-11-18
KR960700625A (ko) 1996-01-20
AU5883194A (en) 1994-08-15
ATE159404T1 (de) 1997-11-15
CA2153167A1 (en) 1994-07-21
DE59404347D1 (de) 1997-11-20

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