ES2108687T3 - Procedimiento para la preparacion de esteres de sulfoxido de 3-exometilencefam. - Google Patents
Procedimiento para la preparacion de esteres de sulfoxido de 3-exometilencefam.Info
- Publication number
- ES2108687T3 ES2108687T3 ES90305254T ES90305254T ES2108687T3 ES 2108687 T3 ES2108687 T3 ES 2108687T3 ES 90305254 T ES90305254 T ES 90305254T ES 90305254 T ES90305254 T ES 90305254T ES 2108687 T3 ES2108687 T3 ES 2108687T3
- Authority
- ES
- Spain
- Prior art keywords
- exometilencefam
- procedure
- preparation
- sulfoxide esters
- conjugated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003462 sulfoxides Chemical class 0.000 title 1
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 3
- -1 SULFOXIDE ESTERS Chemical class 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- HGCIXCUEYOPUTN-UHFFFAOYSA-N cyclohexene Chemical compound C1CCC=CC1 HGCIXCUEYOPUTN-UHFFFAOYSA-N 0.000 abstract 2
- RYPKRALMXUUNKS-UHFFFAOYSA-N hex-2-ene Chemical compound CCCC=CC RYPKRALMXUUNKS-UHFFFAOYSA-N 0.000 abstract 2
- PRBHEGAFLDMLAL-GQCTYLIASA-N (4e)-hexa-1,4-diene Chemical compound C\C=C\CC=C PRBHEGAFLDMLAL-GQCTYLIASA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000001925 cycloalkenes Chemical class 0.000 abstract 1
- UVJHQYIOXKWHFD-UHFFFAOYSA-N cyclohexa-1,4-diene Chemical compound C1C=CCC=C1 UVJHQYIOXKWHFD-UHFFFAOYSA-N 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/08—Preparation by forming the ring or condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Magnetic Record Carriers (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
ESTERES SULFOXUROS 3-EXOMETILENOCEFAN QUE SE OBTIENEN A TRAVES DE LA CICLIZACION DE ESTERES ACIDOS 3-METIL-2-(4-CLOROSULFINIL-2-OXO-3-ACILAMINO-1AZETIDINIL)-3-BUTENOICOS, BAJO CONDICIONES ANHIDROSAS CON CLORURO DE ESTAÑO EN RPESENCIA DE AMBOS Y DE UN COMPUESTO OXO, POR EJEMPLO, UN ETER TAL COMO EL ETER DIETIL, UNA QUETONA TAL COMO LA ACETONA O LA METILETIL QUETONA, Y UN COMPUESTO INSATURADO, POR EJEMPLO, UN ALQUENO TAL COMO EL 1- O 2-HEXENO, UN ALCADIENO CONJUGADO TAL COMO EL 1,4-HEXADIENO, UN CICLOALQUENO TAL COMO EL CICLOHEXENO, UN ALENO, O UN CICLOALCADIENO NO CONJUGADO TAL COMO EL 1,4-CICLOHEXADIENO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/353,128 US4950753A (en) | 1989-05-17 | 1989-05-17 | Process for 3-exomethylenecepham sulfoxide esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2108687T3 true ES2108687T3 (es) | 1998-01-01 |
Family
ID=23387877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90305254T Expired - Lifetime ES2108687T3 (es) | 1989-05-17 | 1990-05-16 | Procedimiento para la preparacion de esteres de sulfoxido de 3-exometilencefam. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4950753A (es) |
| EP (1) | EP0398670B1 (es) |
| JP (1) | JP2951362B2 (es) |
| KR (1) | KR0142871B1 (es) |
| CN (1) | CN1025336C (es) |
| AT (1) | ATE159723T1 (es) |
| AU (1) | AU623771B2 (es) |
| CA (1) | CA2016513C (es) |
| DE (1) | DE69031637T2 (es) |
| DK (1) | DK0398670T3 (es) |
| ES (1) | ES2108687T3 (es) |
| FI (1) | FI902417A0 (es) |
| GR (1) | GR3025674T3 (es) |
| HU (1) | HU208140B (es) |
| IL (1) | IL94356A (es) |
| MX (1) | MX166049B (es) |
| NZ (1) | NZ233656A (es) |
| PH (1) | PH26784A (es) |
| PT (1) | PT94015A (es) |
| RU (1) | RU1833389C (es) |
| ZA (1) | ZA903587B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5159071A (en) * | 1990-09-06 | 1992-10-27 | Ranbaxy Laboratories Limited | Process for the manufacture of 7-amino-3-exomethylene-3-cepham-4-carboxylic acid ester |
| US5126446A (en) * | 1991-01-04 | 1992-06-30 | Eli Lilly And Company | Process for 3-exomethylenecepham sulfoxide esters |
| US5350845A (en) * | 1992-04-08 | 1994-09-27 | Eli Lilly And Company | Process for preparing 7-substituted-amino-3-hydroxy-3-cephem-4-protected carboxy-sulfoxide esters |
| US5604222A (en) * | 1993-12-27 | 1997-02-18 | Lupin Laboratories, Ltd. | Method for the preparation of 2-chloro sulfinyl azetidinones |
| DE4418401C1 (de) * | 1994-05-26 | 1995-06-01 | Heraeus Quarzglas | Verfahren und Vorrichtung zur Herstellung von Platten aus Quarzglas |
| US5578721A (en) * | 1994-07-11 | 1996-11-26 | Lupin Laboratories Limited | Process for preparation of 3-exomethylene cepham sulfoxide esters |
| WO2012103156A1 (en) | 2011-01-25 | 2012-08-02 | Amyris, Inc. | Surfactants |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4052387A (en) * | 1974-12-24 | 1977-10-04 | Eli Lilly And Company | Method of preparation of 3-methylenecephams |
| US4190724A (en) * | 1978-11-13 | 1980-02-26 | Eli Lilly And Company | Process for 3-exomethylenecepham sulfoxides |
| US4289695A (en) * | 1978-11-13 | 1981-09-15 | Eli Lilly And Company | Process for preparing 2-chlorosulfinylazetidinones |
| DE318577T1 (de) * | 1987-06-01 | 1989-12-07 | Master Medical Corp., Phoenix, Ariz. | Flussregelungsanordnung zur administration von intravenoesen fluessigkeiten. |
-
1989
- 1989-05-17 US US07/353,128 patent/US4950753A/en not_active Expired - Lifetime
-
1990
- 1990-05-10 IL IL9435690A patent/IL94356A/en not_active IP Right Cessation
- 1990-05-10 ZA ZA903587A patent/ZA903587B/xx unknown
- 1990-05-10 CA CA002016513A patent/CA2016513C/en not_active Expired - Fee Related
- 1990-05-11 PT PT94015A patent/PT94015A/pt not_active Application Discontinuation
- 1990-05-11 PH PH40508A patent/PH26784A/en unknown
- 1990-05-11 NZ NZ233656A patent/NZ233656A/en unknown
- 1990-05-14 MX MX020691A patent/MX166049B/es unknown
- 1990-05-15 AU AU55064/90A patent/AU623771B2/en not_active Ceased
- 1990-05-15 CN CN90103651A patent/CN1025336C/zh not_active Expired - Fee Related
- 1990-05-15 FI FI902417A patent/FI902417A0/fi not_active Application Discontinuation
- 1990-05-16 DK DK90305254.6T patent/DK0398670T3/da active
- 1990-05-16 HU HU903058A patent/HU208140B/hu unknown
- 1990-05-16 DE DE69031637T patent/DE69031637T2/de not_active Expired - Fee Related
- 1990-05-16 KR KR1019900006990A patent/KR0142871B1/ko not_active IP Right Cessation
- 1990-05-16 ES ES90305254T patent/ES2108687T3/es not_active Expired - Lifetime
- 1990-05-16 RU SU904743891A patent/RU1833389C/ru active
- 1990-05-16 AT AT90305254T patent/ATE159723T1/de not_active IP Right Cessation
- 1990-05-16 EP EP90305254A patent/EP0398670B1/en not_active Expired - Lifetime
- 1990-05-16 JP JP2128070A patent/JP2951362B2/ja not_active Expired - Fee Related
-
1997
- 1997-12-16 GR GR970403323T patent/GR3025674T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL94356A (en) | 1994-06-24 |
| MX166049B (es) | 1992-12-16 |
| DE69031637D1 (de) | 1997-12-04 |
| PT94015A (pt) | 1991-01-08 |
| AU623771B2 (en) | 1992-05-21 |
| HU903058D0 (en) | 1990-09-28 |
| JP2951362B2 (ja) | 1999-09-20 |
| CA2016513A1 (en) | 1990-11-17 |
| NZ233656A (en) | 1992-02-25 |
| JPH035485A (ja) | 1991-01-11 |
| ATE159723T1 (de) | 1997-11-15 |
| AU5506490A (en) | 1990-11-22 |
| IL94356A0 (en) | 1991-03-10 |
| CN1025336C (zh) | 1994-07-06 |
| CA2016513C (en) | 2000-11-21 |
| EP0398670B1 (en) | 1997-10-29 |
| KR0142871B1 (ko) | 1998-07-15 |
| ZA903587B (en) | 1992-01-29 |
| DE69031637T2 (de) | 1998-03-12 |
| US4950753A (en) | 1990-08-21 |
| HUT57217A (en) | 1991-11-28 |
| FI902417A0 (fi) | 1990-05-15 |
| HU208140B (en) | 1993-08-30 |
| GR3025674T3 (en) | 1998-03-31 |
| CN1047294A (zh) | 1990-11-28 |
| DK0398670T3 (da) | 1997-12-15 |
| KR900018116A (ko) | 1990-12-20 |
| EP0398670A3 (en) | 1992-03-18 |
| EP0398670A2 (en) | 1990-11-22 |
| PH26784A (en) | 1992-10-13 |
| RU1833389C (ru) | 1993-08-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX172916B (es) | Procedimiento para la obtencion de preparados vitaminicos | |
| ES2054842T3 (es) | Analogo del factor viii, procedimiento de preparacion y composicion farmaceutica que lo contiene. | |
| DE69213067D1 (de) | Methode zur Herstellung von alpha, beta ungesättigten Ketolactonen | |
| ES2108687T3 (es) | Procedimiento para la preparacion de esteres de sulfoxido de 3-exometilencefam. | |
| ES2140469T3 (es) | Composiciones y metodos terapeuticos y de diagnostico por obtencion de imagenes. | |
| ES2097801T3 (es) | Procedimiento para la obtencion de resinas epoxi. | |
| ES2060295T3 (es) | Procedimiento para preparar un decabromodifenilalcano. | |
| NL7713091A (nl) | Derivaten van de trypsine-callicreine-remmer uit runderorganen (bpti) met proteasen remmende werking en antiflogistische werking, alsmede de bereiding van dergelijke derivaten en preparaten, die deze derivaten bevatten. | |
| AU2439192A (en) | Ester-free ethers | |
| ES2108619B1 (es) | Composicion insecticida/acaricida. | |
| ES2075637T3 (es) | Procedimiento de tincion de fibras queratinicas con un mono- o di-hidroxiindol y un derivado carbonilado aromatico no oxidante, y agente de tincion. | |
| KR860001831A (ko) | 비타민 d₃유도체의 제조방법 | |
| ES2095068T3 (es) | Peroxicarbonatos polimericos y procedimiento para prepararlos. | |
| ES2195149T3 (es) | Densificacion de una estructura porosa (ii). | |
| ES2086791T3 (es) | Procedimiento para la preparacion de 2,3-piridindicarboxilato de dialquilo y derviados del mismo a partir de una oxima alfa, beta-insaturada y un aminobutendioato. | |
| ATE121293T1 (de) | Verwendung eines stoffes, dessen hauptbestandteil ein triglyzerid ist, als wirkstoff mit biologischer wirkung auf die darmmucosa sowie zubereitung die diesen wirkstoff enthält. | |
| DE3886476D1 (de) | Wässrige Silicondispersionen. | |
| ES2037278T3 (es) | Tratamiento de la esterilidad. | |
| ES2089607T3 (es) | Procedimiento para la obtencion de 1-fluorciclopropil-metil-cetona. | |
| ES2045215T3 (es) | (+)-o (+)-1-(2-n-aminoetil sustituido) -1-metil-7-metoxi-1,2,3,4-tetrahidronaftaleno, y procedimiento para su produccion. | |
| BR8702013A (pt) | Processo de preparacao de compostos carbonilados etilenicos | |
| ES2032914T3 (es) | Procedimiento para preparar composiciones con diclorotrifluoetano. | |
| ATE103967T1 (de) | Verfahren zur herstellung von addukten von 1,2butylenoxid an alkohole. | |
| ATE38919T1 (de) | Verfahren zur herstellung einer roentgenroehrendrehanode und eine nach diesem verfahren hergestellte roentgenroehrendrehanode. | |
| JPS57183783A (en) | Manufacture of cholesterol derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 398670 Country of ref document: ES |