ES2102259T3 - Procedimiento y dispositivo para el analisis de glucosa en una matriz biologica. - Google Patents

Procedimiento y dispositivo para el analisis de glucosa en una matriz biologica.

Info

Publication number
ES2102259T3
ES2102259T3 ES94931505T ES94931505T ES2102259T3 ES 2102259 T3 ES2102259 T3 ES 2102259T3 ES 94931505 T ES94931505 T ES 94931505T ES 94931505 T ES94931505 T ES 94931505T ES 2102259 T3 ES2102259 T3 ES 2102259T3
Authority
ES
Spain
Prior art keywords
light
biological matrix
pct
glucose concentration
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94931505T
Other languages
English (en)
Inventor
Matthias Essenpreis
Dirk Bocker
Heinz-Michael Hein
Hans-Peter Haar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2102259T3 publication Critical patent/ES2102259T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
    • A61B2562/0242—Special features of optical sensors or probes classified in A61B5/00 for varying or adjusting the optical path length in the tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/069—Supply of sources
    • G01N2201/0696—Pulsed

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO Y UN DISPOSITIVO PARA LA DETERMINACION ANALITICA DE LA CONCENTRACION DE GLUCOSA EN UNA MATRIZ BIOLOGICA. DE ACUERDO CON EL INDICADO PROCEDIMIENTO, EN UNA ETAPA DE DETECCION SE IRRADIA LUZ A PARTIR DE UN TRANSMISOR DE LUZ A TRAVES DE LA SUPERFICIE PERIMETRICA DE UNA MATRIZ BIOLOGICA COMO LUZ PRIMARIA. LA LUZ ABANDONANDO LA MATRIZ BIOLOGICA A TRAVES DE UNA SUPERFICIE CIRCUNDANTE SE DETECTA EN UN RECEPTOR DE LUZ A FIN DE DETERMINAR UNA PROPIEDAD FISICA MEDIBLE DE LA LUZ, QUE PUEDE VARIAR DEBIDO A LA INTERACCION CON LA MATRIZ BIOLOGICA Y QUE SE CORRELACIONA CON LA CONCENTRACION DE GLUCOSA EN LA INDICADA MATRIZ BIOLOGICA. EN UNA ETAPA DE EVALUACION, LA CONCENTRACION DE GLUCOSA SE ENCUENTRA EN LA BASE DEL CAMBIO DE LA INDICADA PROPIEDAD FISICA DE LA LUZ DETERMINADA EN AL MENOS UNA ETAPA DE DETECCION, EN RELACION A UN VALOR CALIBRADO. PARA OBTENER CON UN PROCEDIMIENTO DE ESTE TIPO BUENA PRECISION ANALITICA, POR EJEMPLO PARA OBSERVAR EL CAMBIO EN LA CONCENTRACION ANALITICA (CONTROL CICLICO) SOBRE UN PERIODO SUFICIENTE, COMO LA PROPIEDAD QUE PUEDE SER MEDIDA EN LA ETAPA DE DETECCION CORRELACIONADA CON LA CONCENTRACION DE GLUCOSA ES UTILIZADO UN PARAMETRO CORRESPONDIENTE AL TIEMPO DE PROPAGACION DE LA LUZ DENTRO DE LA MATRIZ BIOLOGICA ENTRE UN PUNTO DE IRRADIACION DEFINIDO Y UN PUNTO DE DETECCION DEFINIDO.
ES94931505T 1993-11-04 1994-10-29 Procedimiento y dispositivo para el analisis de glucosa en una matriz biologica. Expired - Lifetime ES2102259T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4337570A DE4337570A1 (de) 1993-11-04 1993-11-04 Verfahren zur Analyse von Glucose in einer biologischen Matrix

Publications (1)

Publication Number Publication Date
ES2102259T3 true ES2102259T3 (es) 1997-07-16

Family

ID=6501730

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94931505T Expired - Lifetime ES2102259T3 (es) 1993-11-04 1994-10-29 Procedimiento y dispositivo para el analisis de glucosa en una matriz biologica.

Country Status (18)

Country Link
US (1) US5692504A (es)
EP (1) EP0726729B1 (es)
JP (1) JPH09504718A (es)
KR (1) KR960705500A (es)
AT (1) ATE151616T1 (es)
AU (1) AU683505B2 (es)
CA (1) CA2174441A1 (es)
DE (2) DE4337570A1 (es)
DK (1) DK0726729T3 (es)
ES (1) ES2102259T3 (es)
FI (1) FI961724A (es)
GR (1) GR3023463T3 (es)
IL (1) IL111525A (es)
NO (1) NO961810L (es)
NZ (1) NZ275078A (es)
TW (1) TW356516B (es)
WO (1) WO1995012348A1 (es)
ZA (1) ZA948666B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020152380A1 (es) 2019-01-22 2020-07-30 Universidad De Sevilla Dispositivo portable y método para la estimación no invasiva del nivel de glucosa en sangre

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Publication number Priority date Publication date Assignee Title
WO2020152380A1 (es) 2019-01-22 2020-07-30 Universidad De Sevilla Dispositivo portable y método para la estimación no invasiva del nivel de glucosa en sangre

Also Published As

Publication number Publication date
EP0726729A1 (de) 1996-08-21
NZ275078A (en) 1997-01-29
NO961810D0 (no) 1996-05-03
FI961724A0 (fi) 1996-04-19
NO961810L (no) 1996-05-03
DE4337570A1 (de) 1995-05-11
DK0726729T3 (da) 1997-10-20
DE59402462D1 (de) 1997-05-22
ATE151616T1 (de) 1997-05-15
IL111525A0 (en) 1995-01-24
JPH09504718A (ja) 1997-05-13
EP0726729B1 (de) 1997-04-16
TW356516B (en) 1999-04-21
ZA948666B (en) 1996-05-03
GR3023463T3 (en) 1997-08-29
WO1995012348A1 (de) 1995-05-11
KR960705500A (ko) 1996-11-08
FI961724A (fi) 1996-04-19
AU8056994A (en) 1995-05-23
US5692504A (en) 1997-12-02
CA2174441A1 (en) 1995-05-11
IL111525A (en) 1998-09-24
AU683505B2 (en) 1997-11-13

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