ES2098359T5 - Peptidos sinteticos y sus mezclas para detectar anticuerpos contra hiv. - Google Patents

Peptidos sinteticos y sus mezclas para detectar anticuerpos contra hiv.

Info

Publication number
ES2098359T5
ES2098359T5 ES91911697T ES91911697T ES2098359T5 ES 2098359 T5 ES2098359 T5 ES 2098359T5 ES 91911697 T ES91911697 T ES 91911697T ES 91911697 T ES91911697 T ES 91911697T ES 2098359 T5 ES2098359 T5 ES 2098359T5
Authority
ES
Spain
Prior art keywords
hiv
peptides
sequence
aminoid
mixtures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91911697T
Other languages
English (en)
Other versions
ES2098359T3 (es
Inventor
Martial Lacroix
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adaltis Inc
Original Assignee
Adaltis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24195143&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2098359(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adaltis Inc filed Critical Adaltis Inc
Publication of ES2098359T3 publication Critical patent/ES2098359T3/es
Application granted granted Critical
Publication of ES2098359T5 publication Critical patent/ES2098359T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE PRESENTAN PEPTIDOS CICLICOS DE LAS FORMULAS (I) Y (III), EN DONDE X REPRESENTA UNA SECUENCIA AMINOACIDA DE LA POSICION 584 A LA 604 (GP41-VIH-1) CARACTERIZANDOSE DICHAS SECUENCIAS AMINOACIDAS PORQUE AL MENOS UNA ES DE UNA LISINA EN LA POSICION 586 O UNA LISINA TANTO EN LA POSICION 585 COMO EN LA 586; X2 REPRESENTA UNA SECUENCIA AMINOACIDA DE LA POSICION 585 A LA 604 (GP41-VIH-1); Y REPRESENTA UNA SECUENCIA AMINOACIDA DE LA POSICION 612 A LA 629 (GP41-VIH-1); E Y F REPRESENTAN UNO O MAS EPITOPES INCLUIDOS EN LA SECUENCIA AMINOACIDA QUE SE EXTIENDEN DE 586 A 629 (GP41-VIH-1) O DE 578 A 613 (GP36-VIH-2); Y A Y B REPRESENTAN LOS TERMINALES AMINO Y CARBOXI RESPECTIVAMENTE, ASI COMO SUSTITUYENTES QUE SON EFECTIVOS PARA HACER QUE EL PEPTIDO SEA MAS UTIL COMO REACTIVO DE INMUNODIAGNOSTICO. LOS PEPTIDOS DE LA FORMULA III TIENE BIEN A E O A F O A LOS DOS PRESENTES. TAMBIEN SE PRESENTAN PEPTIDOS DE LAS FORMULAS GENERALES (II) Y (IV), EN DONDE X1 REPRESENTA UNA SECUENCIA AMINOACIDA DE LA POSICION 577 A LA 596 (GP36-VIH-2) CARACTERIZANDOSE TALES SECUENCIAS AMINOACIDAS PORQUE AL MENOS UNA ES DE UNA LISIAN EN LA POSICION 578 O UNA LISINA EN LAS DOS POSICIONES 577 Y 578; X3 REPRESENTA UNA SECUENCIA AMINOACIDA DE LA POSICION 577 A LA 596 (GP36-VIH-2); Y1 REPRESENTA UNA SECUENCIA AMINOACIDA DE 578 A 612 (GP36-VIH-2) O DE 586 A 629 (GP41-VIH-1); Y A Y B SON COMO SE HAN DEFINIDO ARRIBA. LOS PEPTIDOS DE LA FORMULA (IV) TIENEN A E O A F O A LOS DOS PRESENTES. ESTOS PEPTIDOS CICLICOS POR SI SOLOS O MEZCLADOS CON OTROS PEPTIDOS SON PARTICULARMENTE UTILES PARA LA DETECCION DE ANTICUERPOS DEL VIH-1 Y EL VIH-2 EN MUESTRAS DE ANALISIS Y EN SUEROS.
ES91911697T 1990-07-09 1991-07-08 Peptidos sinteticos y sus mezclas para detectar anticuerpos contra hiv. Expired - Lifetime ES2098359T5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/549,964 US5241047A (en) 1988-12-08 1990-07-09 Synthetic peptides and mixtures thereof for detecting HIV antibodies

Publications (2)

Publication Number Publication Date
ES2098359T3 ES2098359T3 (es) 1997-05-01
ES2098359T5 true ES2098359T5 (es) 2001-10-16

Family

ID=24195143

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91911697T Expired - Lifetime ES2098359T5 (es) 1990-07-09 1991-07-08 Peptidos sinteticos y sus mezclas para detectar anticuerpos contra hiv.

Country Status (17)

Country Link
US (1) US5241047A (es)
EP (1) EP0538283B2 (es)
JP (1) JP3533214B2 (es)
AP (1) AP9100291A0 (es)
AT (1) ATE150031T1 (es)
AU (1) AU664828B2 (es)
CA (1) CA2086922C (es)
CS (1) CS209691A3 (es)
DE (1) DE69125161T3 (es)
ES (1) ES2098359T5 (es)
IE (1) IE912377A1 (es)
IL (1) IL98769A (es)
MX (1) MX9100115A (es)
NZ (1) NZ238856A (es)
PT (1) PT98249B (es)
WO (1) WO1992000997A1 (es)
ZA (1) ZA915286B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6210874B1 (en) * 1988-01-27 2001-04-03 Biochem Immunosystems, Inc. Synthetic peptides and mixtures thereof for detecting HIV antibodies
US6479055B1 (en) 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
US6017536A (en) * 1993-06-07 2000-01-25 Trimeris, Inc. Simian immunodeficiency virus peptides with antifusogenic and antiviral activities
US6518013B1 (en) 1993-06-07 2003-02-11 Trimeris, Inc. Methods for the inhibition of epstein-barr virus transmission employing anti-viral peptides capable of abrogating viral fusion and transmission
JPH08510063A (ja) * 1994-03-02 1996-10-22 アボツト・ラボラトリーズ リコンビナントタンパクおよび合成ペプチド試薬を用いるｈｉｖイムノアッセイ
EP0993615A1 (en) * 1998-03-04 2000-04-19 Universal Healthwatch, Inc. Rapid confirmatory test for microbial infections
DE10106295C1 (de) * 2001-02-02 2002-08-22 Gaifar German American Inst Fo Protein mit mehreren Antigen-Epitop-Sequenzen, welches immobilisiert ist
CA2571168A1 (en) * 2004-06-17 2006-01-26 Mannkind Corporation Mhc i-binding ssx-241-49 variants
EP2295973A1 (en) * 2004-09-08 2011-03-16 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services Compositions and methods for the detection of HIV-1/HIV-2 infection.
WO2007141650A2 (en) * 2006-01-17 2007-12-13 Instituto De Medicina Molecular Compositions and methods for diagnosing hiv-2 infection
CN109983026B (zh) * 2016-12-09 2023-09-19 富士胶片株式会社 混合模式亲和层析用载体
CN109374884B (zh) * 2018-12-24 2021-10-22 四川沃文特生物技术有限公司 一种pct浓度检测试剂盒及其制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4774175A (en) * 1985-03-01 1988-09-27 Centocor, Inc. Immunochemical methods for the detection of antibody against HTLV-III
US4629783A (en) * 1985-04-29 1986-12-16 Genetic Systems Corporation Synthetic antigen for the detection of AIDS-related disease
WO1986006414A1 (en) * 1985-04-29 1986-11-06 Genetic Systems Corporation Synthetic antigens for the detection of aids-related disease
US4735896A (en) * 1986-03-04 1988-04-05 United Biomedical, Inc. Synthetic peptide and process of using same for the detection and diagnosis of AIDS and pre-AIDS conditions
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
AU7234387A (en) * 1986-03-24 1987-10-20 Ortho Pharmaceutical Corporation Synthetic htlv-iii peptides, compositions and uses thereof
US4879212A (en) * 1986-04-02 1989-11-07 United Biomedical Inc. Peptide composition and method for the detection of antibodies to HTLV-III
EP0247557B1 (en) * 1986-05-27 1994-04-20 F. Hoffmann-La Roche Ag HTLV-III(LAV) Envelope peptides
US4957737A (en) * 1986-05-27 1990-09-18 Hoffmann-La Roche Inc. HTLV-III (LAV) envelope peptides
US4812556A (en) * 1987-05-18 1989-03-14 Virovahl Synthetic peptide antigen for the detection of HIV-2 infection
SE8704185L (sv) * 1987-10-28 1989-04-29 Ferring Ab Nya peptider, artificiella antigener och immunoanalystestsatser
AU627701B2 (en) * 1987-10-28 1992-09-03 Euro-Diagnostica Ab Hiv peptides, artificial hiv antigens and immunoassay kits
IL88963A (en) * 1988-01-27 1996-05-14 Iaf Biochem Int Circular synthetic peptides and their mixtures for the detection of VIH antibodies and for the formation of vaccines
DE3901857A1 (de) * 1989-01-23 1990-07-26 Boehringer Mannheim Gmbh Verfahren zur bestimmung von hiv 2 antikoerpern

Also Published As

Publication number Publication date
CS209691A3 (en) 1992-03-18
CA2086922C (en) 2003-01-14
CA2086922A1 (en) 1992-01-10
IE912377A1 (en) 1992-01-15
PT98249A (pt) 1992-05-29
JP3533214B2 (ja) 2004-05-31
US5241047A (en) 1993-08-31
ZA915286B (en) 1993-03-31
MX9100115A (es) 1992-02-28
ATE150031T1 (de) 1997-03-15
AU8189591A (en) 1992-02-04
IL98769A0 (en) 1992-07-15
DE69125161T3 (de) 2002-03-07
WO1992000997A1 (en) 1992-01-23
ES2098359T3 (es) 1997-05-01
PT98249B (pt) 1998-12-31
JPH05508837A (ja) 1993-12-09
EP0538283B2 (en) 2001-08-01
AP9100291A0 (en) 1993-01-09
NZ238856A (en) 1992-12-23
EP0538283A1 (en) 1993-04-28
IL98769A (en) 1997-11-20
AU664828B2 (en) 1995-12-07
DE69125161D1 (de) 1997-04-17
EP0538283B1 (en) 1997-03-12
DE69125161T2 (de) 1997-06-19

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