ES2029041T3 - Procedimiento para la preparacion de nuevos peptidos derivados de la cck8. - Google Patents

Procedimiento para la preparacion de nuevos peptidos derivados de la cck8.

Info

Publication number
ES2029041T3
ES2029041T3 ES198888400459T ES88400459T ES2029041T3 ES 2029041 T3 ES2029041 T3 ES 2029041T3 ES 198888400459 T ES198888400459 T ES 198888400459T ES 88400459 T ES88400459 T ES 88400459T ES 2029041 T3 ES2029041 T3 ES 2029041T3
Authority
ES
Spain
Prior art keywords
image
radical
cck8
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888400459T
Other languages
English (en)
Inventor
Bruno Charpentier
Bernard Pierre Roques
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Application granted granted Critical
Publication of ES2029041T3 publication Critical patent/ES2029041T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/595—Gastrins; Cholecystokinins [CCK]
    • C07K14/5955—Gastrins; Cholecystokinins [CCK] at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PEPTIDOS DE FORMULA (I) EN LA QUE X=H O UN RADICAL PROTECTOR DE FUNCION AMINA, R=H O SO3H, A Y D SON: - BIEN DIFERENTES REPRESENTAN UNO UN RADICAL (II), Y OTRO UN RADICAL (III); M Y N ESTAN COMPRENDIDOS ENTRE 1 Y 5, ENTENDIENDOSE QUE A Y D FORMAN UN CICLO POR AMIDIFICACION DE SUS CADENAS LATERALES, - SIENDO IGUALES O DIFERENTES REPRESENTAN UNO DE LOS RADICALES SIGUIENTES (III) CON P=1 O 2, ETENDIENDOSE QUE A Y D FORMANUN CICLO POR PUENTE OXIDANTE ENTRE LOS ATOMOS DE AZUFRE; B Y E=MET, NLE, SER, THR, ALLO- THYR O CIS O HCY CUYAS FUNCIONES OH Y SH SON LIBRES O PROTEGIDAS; F=UNION DE VALENCIA O PHE, TYR (OCH3)O CHA. Q=H O ALCOILO (1 A 6 C), FENILO O FENILALCOILO, ESTANDO ESTOS RADICALES NO SUSTITUIDOS O SUSTITUIDOS POR ATOMOS DE FLUOR, SIENDO LOS ACIDOS AMINADOS D, L O DL. ESTOS PRODUCTOS SON UTILES EN PARTICULAS COMO NEUROSICOTROPOS.
ES198888400459T 1987-03-02 1988-02-29 Procedimiento para la preparacion de nuevos peptidos derivados de la cck8. Expired - Lifetime ES2029041T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8702770A FR2611722B1 (fr) 1987-03-02 1987-03-02 Nouveaux peptides derives de la cck8, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ES2029041T3 true ES2029041T3 (es) 1992-07-16

Family

ID=9348488

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888400459T Expired - Lifetime ES2029041T3 (es) 1987-03-02 1988-02-29 Procedimiento para la preparacion de nuevos peptidos derivados de la cck8.

Country Status (9)

Country Link
US (1) US4985406A (es)
EP (1) EP0283365B1 (es)
JP (1) JPS63238099A (es)
AT (1) ATE65086T1 (es)
CA (1) CA1310444C (es)
DE (1) DE3863560D1 (es)
ES (1) ES2029041T3 (es)
FR (1) FR2611722B1 (es)
GR (1) GR3002316T3 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02269784A (ja) * 1989-04-11 1990-11-05 Chisso Corp 塗装鋼板用塗料組成物
US5115098A (en) * 1990-02-28 1992-05-19 President And Fellows Of Harvard College End-blocked peptides inhibiting binding capacity of gp120
IL99628A (en) * 1991-10-02 2004-07-25 Yissum Res Dev Co Processes for the preparation of cyclic peptides, and pharmaceutical compositions containing them
GB0105069D0 (en) * 2001-03-01 2001-04-18 Univ Ulster The Modified peptide
FR2823212B1 (fr) * 2001-04-10 2005-12-02 Inst Nat Sante Rech Med Inhibiteurs de la toxine botulique de type b
FR2931151A1 (fr) * 2008-05-13 2009-11-20 Pharmaleads Soc Par Actions Si Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique
IT202000019708A1 (it) * 2020-08-07 2022-02-07 Ospedale Pediatrico Bambino Gesù Peptidi in grado di legare il recettore enzima di conversione dell'angiotensina 2 (ACE2) e loro usi medici

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3705140A (en) * 1967-10-05 1972-12-05 Luigi Bernardi Peptides related to the c-terminal sequence of cck-pz and caerulein
US3981303A (en) * 1971-09-09 1976-09-21 Alza Corporation Bioerodible ocular device
US4490364A (en) * 1983-05-20 1984-12-25 The Salk Institute For Biological Studies CCK Agonists II
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4769445A (en) * 1985-03-04 1988-09-06 Pennwalt Corporation Process for the solid phase synthesis of peptides which contain sulfated tyrosine
US4808701A (en) * 1987-03-30 1989-02-28 Hoffmann-La Roche Inc. Cyclic peptides having appetite regulating activity

Also Published As

Publication number Publication date
GR3002316T3 (en) 1992-12-30
DE3863560D1 (de) 1991-08-14
FR2611722B1 (fr) 1989-08-11
JPS63238099A (ja) 1988-10-04
EP0283365B1 (fr) 1991-07-10
EP0283365A1 (fr) 1988-09-21
US4985406A (en) 1991-01-15
FR2611722A1 (fr) 1988-09-09
CA1310444C (fr) 1992-11-17
ATE65086T1 (de) 1991-07-15

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