NO904291D0 - Fremgangsmaate for fremstilling av radiomerkede antikoagulerende peptider. - Google Patents

Fremgangsmaate for fremstilling av radiomerkede antikoagulerende peptider.

Info

Publication number
NO904291D0
NO904291D0 NO904291A NO904291A NO904291D0 NO 904291 D0 NO904291 D0 NO 904291D0 NO 904291 A NO904291 A NO 904291A NO 904291 A NO904291 A NO 904291A NO 904291 D0 NO904291 D0 NO 904291D0
Authority
NO
Norway
Prior art keywords
anticoagulating
peptides
marked
radio
procedure
Prior art date
Application number
NO904291A
Other languages
English (en)
Other versions
NO904291L (no
Inventor
John Leonard Krstenansky
Simon Jen Tan Mao
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO904291D0 publication Critical patent/NO904291D0/no
Publication of NO904291L publication Critical patent/NO904291L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81Protease inhibitors
    • G01N2333/815Protease inhibitors from leeches, e.g. hirudin, eglin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NO90904291A 1989-10-03 1990-10-02 Fremgangsmaate for fremstilling av radiomerkede antikoagulerende peptider. NO904291L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41633589A 1989-10-03 1989-10-03

Publications (2)

Publication Number Publication Date
NO904291D0 true NO904291D0 (no) 1990-10-02
NO904291L NO904291L (no) 1991-04-04

Family

ID=23649537

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90904291A NO904291L (no) 1989-10-03 1990-10-02 Fremgangsmaate for fremstilling av radiomerkede antikoagulerende peptider.

Country Status (18)

Country Link
US (1) US5279812A (no)
EP (1) EP0421366B1 (no)
JP (1) JP2899390B2 (no)
KR (1) KR0168644B1 (no)
CN (1) CN1050721A (no)
AT (1) ATE125269T1 (no)
AU (1) AU631681B2 (no)
CA (1) CA2026377A1 (no)
DE (1) DE69021000T2 (no)
ES (1) ES2076999T3 (no)
FI (1) FI904851A0 (no)
HU (1) HU207525B (no)
IE (1) IE903531A1 (no)
IL (1) IL95864A0 (no)
NO (1) NO904291L (no)
NZ (1) NZ235499A (no)
PT (1) PT95485A (no)
ZA (1) ZA907743B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395609A (en) * 1989-06-19 1995-03-07 Antisoma Limited Synthetic peptides for use in tumor detection
GB8914020D0 (en) * 1989-06-19 1989-08-09 Antisoma Ltd Synthetic peptides for use in thrombus detection
DK0540574T3 (da) * 1990-07-24 1996-09-30 Merrell Pharma Inc Antikoagulationspeptider
US5574012A (en) * 1990-07-24 1996-11-12 Merrell Pharmaceuticals Inc. Analogs of hirudin having anti-platelet activity
ZA915658B (en) * 1990-07-24 1992-05-27 Merrell Dow Pharma Analogs of hirudin having antiplatelet activity
WO1993004082A1 (en) * 1991-08-20 1993-03-04 Baxter International Inc. Analogs of hirudin
AU3606793A (en) * 1992-02-05 1993-09-03 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US5371184A (en) * 1992-02-05 1994-12-06 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5750088A (en) 1993-03-30 1998-05-12 The Dupont Merck Pharmaceutical Company Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals
CN1124964A (zh) * 1993-06-11 1996-06-19 默里尔药物公司 三功能抗凝血酶和抗血小板的肽
US5457177A (en) * 1993-06-16 1995-10-10 Merck & Co., Inc. Thrombin receptor radioligands
US5780509A (en) * 1994-05-24 1998-07-14 Muromachi Kagaku Kogyo Kaisha, Ltd. Compound bearing two, 2,6-diiodophenol-4-YL groups and diagnostic drug for iodine allergy
US5808146A (en) * 1995-11-09 1998-09-15 Emory University Amino acid analogs for tumor imaging
US6808698B1 (en) 1999-03-26 2004-10-26 Bristol-Myers Squibb Pharma Company Method for localization of blood clots
US6254852B1 (en) 1999-07-16 2001-07-03 Dupont Pharmaceuticals Company Porous inorganic targeted ultrasound contrast agents
US6685914B1 (en) * 1999-09-13 2004-02-03 Bristol-Myers Squibb Pharma Company Macrocyclic chelants for metallopharmaceuticals
US7544715B2 (en) * 2002-04-30 2009-06-09 Emory University Tumor imaging compounds
US7317104B2 (en) 2003-06-13 2008-01-08 Bristol-Myers Squibb Pharma Company Chelants and macrocyclic metal complex radiopharmaceuticals thereof
US7319149B2 (en) * 2003-06-13 2008-01-15 Bristol-Myers Squibb Pharma Company Chelants and macrocyclic metal complex radiopharmaceuticals thereof
CN100402092C (zh) * 2005-06-07 2008-07-16 西安交通大学 血栓诊断和/或治疗用含气干粉活性剂及其制备工艺
US20060292073A1 (en) * 2005-06-23 2006-12-28 Emory University Stereoselective Synthesis of Amino Acid Analogs for Tumor Imaging
US7837982B2 (en) * 2005-06-23 2010-11-23 Emory University Imaging agents
US8246752B2 (en) 2008-01-25 2012-08-21 Clear Catheter Systems, Inc. Methods and devices to clear obstructions from medical tubes
CN110437307B (zh) * 2019-07-26 2020-11-13 暨南大学 一类具抗血栓和脑神经细胞保护作用的水蛭多肽及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5850213B2 (ja) * 1977-06-20 1983-11-09 株式会社第一ラジオアイソト−プ研究所 カルチトニンの定量法
DE3040824A1 (de) * 1980-10-30 1982-08-19 Dr. Karl Thomae Gmbh, 7950 Biberach Neues dekapeptid, verfahren zu seiner herstellung und verwendung
US4455290A (en) * 1981-04-02 1984-06-19 Research Corporation Inhibition of fibrin polymerization by a peptide isolated from fibrin Fragment D1
US4585740A (en) * 1983-05-03 1986-04-29 The Whittier Institute For Diabetes And Endocrinology Prolactin immunoassay using synthetic peptide
FR2550204B1 (fr) * 1983-08-05 1987-11-13 Toyo Jozo Kk Derives peptidiques de (nle8,nle1b, tyr34)-h-pth
DE3445532A1 (de) * 1984-12-13 1986-06-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn Hirudin-pa, desulfatohirudine-pa, verfahren zur herstellung und pharmazeutische mittel, die diese wirkstoffe enthalten
DE3689525D1 (de) * 1985-07-17 1994-02-24 Hoechst Ag Neue Polypeptide mit blutgerinnungshemmender Wirkung, Verfahren zu deren Herstellung bzw. Gewinnung, deren Verwendung und diese enthaltende Mittel.
CA1341032C (en) * 1987-01-23 2000-06-20 John L. Krstenansky Anticoagulant peptides
ZA883444B (no) * 1987-05-21 1988-11-16
CA1340646C (en) * 1987-05-21 1999-07-13 John L. Krstenansky Cyclic anticoagulant peptides
AU3098289A (en) * 1988-03-04 1989-09-07 Biogen, Inc. Hirudin peptides
ES2052062T3 (es) * 1988-06-11 1994-07-01 Ciba Geigy Ag Nuevos polipeptidos con actividad anticoagulante.
US5192747A (en) * 1989-10-03 1993-03-09 Merrell Dow Pharmaceuticals Inc. Anticoagulant peptides

Also Published As

Publication number Publication date
PT95485A (pt) 1991-06-25
JP2899390B2 (ja) 1999-06-02
EP0421366B1 (en) 1995-07-19
HU207525B (en) 1993-04-28
HU906271D0 (en) 1991-03-28
ES2076999T3 (es) 1995-11-16
ZA907743B (en) 1991-07-31
DE69021000D1 (de) 1995-08-24
HUT55801A (en) 1991-06-28
AU631681B2 (en) 1992-12-03
KR910007959A (ko) 1991-05-30
ATE125269T1 (de) 1995-08-15
FI904851A0 (fi) 1990-10-02
US5279812A (en) 1994-01-18
NZ235499A (en) 1993-04-28
DE69021000T2 (de) 1996-04-04
AU6368990A (en) 1991-04-11
CN1050721A (zh) 1991-04-17
IL95864A0 (en) 1991-07-18
JPH03120296A (ja) 1991-05-22
EP0421366A1 (en) 1991-04-10
CA2026377A1 (en) 1991-04-04
KR0168644B1 (ko) 1999-01-15
NO904291L (no) 1991-04-04
IE903531A1 (en) 1991-04-10

Similar Documents

Publication Publication Date Title
NO904291L (no) Fremgangsmaate for fremstilling av radiomerkede antikoagulerende peptider.
NO880268L (no) Fremgangsmaate for fremstilling av antikoagulerende peptider.
NO904292L (no) Fremgangsmaate for fremstilling av antikoagulerende peptider.
NO882238L (no) Fremgangsmaate for fremstilling av cykliske antikoagulerende peptider.
DE3880194D1 (de) Zyklisches antikoagulierendes peptid.
NO894880D0 (no) Fremgangsmaate for fremstilling av antikoagulerende peptider.
NO891894L (no) Fremgangsmaate for fremstilling av antikoagulerende peptidalkoholer.
HU9300191D0 (en) Anti-coagulant peptides