ES2094907T3 - Secuencias de adn que codifican para caracteristicas de virulencia de -s(streptococcus suis) y partes del mismo, polipeptidos y anticuerpos derivados de este y su uso para la diagnosis y la proteccion contra la infeccion por -s(s. suis) en mamiferos, incluyendo el ser humano. - Google Patents
Secuencias de adn que codifican para caracteristicas de virulencia de -s(streptococcus suis) y partes del mismo, polipeptidos y anticuerpos derivados de este y su uso para la diagnosis y la proteccion contra la infeccion por -s(s. suis) en mamiferos, incluyendo el ser humano.Info
- Publication number
- ES2094907T3 ES2094907T3 ES92908242T ES92908242T ES2094907T3 ES 2094907 T3 ES2094907 T3 ES 2094907T3 ES 92908242 T ES92908242 T ES 92908242T ES 92908242 T ES92908242 T ES 92908242T ES 2094907 T3 ES2094907 T3 ES 2094907T3
- Authority
- ES
- Spain
- Prior art keywords
- suis
- polypeptides
- antibodies derived
- diagnosis
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 108091028043 Nucleic acid sequence Proteins 0.000 title abstract 2
- 241000194021 Streptococcus suis Species 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 230000004224 protection Effects 0.000 title abstract 2
- 230000001018 virulence Effects 0.000 title abstract 2
- 241000282414 Homo sapiens Species 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 102000016943 Muramidase Human genes 0.000 abstract 1
- 108010014251 Muramidase Proteins 0.000 abstract 1
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 235000010335 lysozyme Nutrition 0.000 abstract 1
- 229940051921 muramidase Drugs 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/885—Streptococcus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
LA INVENCION SE REFIERE A SECUENCIAS DE DNA QUE CODIFICAN POLIPEPTIDOS QUE SON CARACTERISTICOS PARA LA VIRULENCIA DE LA BACTERIA PATOGENA "STREPTOCOCCUS SUIS" Y PARTES DE LAS MISMAS, Y POLIPEPTIDOS Y ANTICUERPOS DERIVADOS DE LAS MISMAS. LAS SECUENCIAS CODIFICAN UN POLIPEPTIDOS DE ENTRE 90000 Y 120000 DALTONS O UN POLIPEPTIDO DE PESO MOLECULAR MAYOR QUE CONTIENE DICHO POLIPEPTIDO Y UN POLIPEPTIDO DE ENTRE 135000 Y 136000 DALTONS (PROTEINA RELACIONADA CON LA MURAMIDASA), O PARTES DEL MISMO. LAS SECUENCIAS MISMAS, Y TAMBIEN LOS POLIPEPTIDOS Y ANTICUERPOS DERIVADOS DE LAS MISMAS, SE USAN PARA LA DIAGNOSIS Y PROTECCION CONTRA LA INFECCION POR EL "S. SUIS" EN MAMIFEROS INCLUYENDO EL HOMBRE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL9100510A NL9100510A (nl) | 1991-03-21 | 1991-03-21 | Dna-sequenties die coderen voor kenmerken van virulentie van streptococcus suis en delen daarvan, daarvan afgeleide polypeptiden en antilichamen, alsmede toepassing daarvan bij de diagnose van en de bescherming tegen infectie met s. suis bij zoogdieren, waaronder de mens. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2094907T3 true ES2094907T3 (es) | 1997-02-01 |
Family
ID=19859048
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92908242T Expired - Lifetime ES2094907T3 (es) | 1991-03-21 | 1992-03-19 | Secuencias de adn que codifican para caracteristicas de virulencia de -s(streptococcus suis) y partes del mismo, polipeptidos y anticuerpos derivados de este y su uso para la diagnosis y la proteccion contra la infeccion por -s(s. suis) en mamiferos, incluyendo el ser humano. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5610011A (es) |
EP (1) | EP0575497B1 (es) |
JP (1) | JP2776633B2 (es) |
CN (1) | CN1055500C (es) |
AT (1) | ATE143693T1 (es) |
AU (1) | AU659637B2 (es) |
CA (1) | CA2105057C (es) |
DE (1) | DE69214277T2 (es) |
DK (1) | DK0575497T3 (es) |
ES (1) | ES2094907T3 (es) |
GR (1) | GR3022052T3 (es) |
NL (1) | NL9100510A (es) |
NZ (1) | NZ242037A (es) |
WO (1) | WO1992016630A1 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6015889A (en) * | 1993-03-19 | 2000-01-18 | Gunnar Lindahl | Protein rib, a cell surface protein that confers immunity to many strains of the group B streptococcus: process for purification of the protein, reagent kit and pharmaceutical composition |
US5726016A (en) * | 1995-01-18 | 1998-03-10 | The Trustees Of The University Of Pennsylvania | Compositions and methods for diagnosis of diseases associated with actinobacillus actinomycetemcomitans infection |
ATE219146T1 (de) * | 1995-01-30 | 2002-06-15 | Lunamed Ag | Antitumorpräparate, die eine lipoteichonsäure aus streptococcus enthalten |
ES2512496T3 (es) | 1998-07-22 | 2014-10-24 | Stichting Dienst Landbouwkundig Onderzoek | Vacunas y pruebas de diagnóstico de Streptococcus suis |
EP1205552A1 (en) * | 2000-11-09 | 2002-05-15 | ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. | Virulence of streptococci, involving ORFs from Streptococcus suis |
US6905816B2 (en) * | 2000-11-27 | 2005-06-14 | Intelligent Medical Devices, Inc. | Clinically intelligent diagnostic devices and methods |
JP4275413B2 (ja) | 2001-02-02 | 2009-06-10 | イーデー−レーリスタット,インスティチュート フォール ディールハウデレイ エン ディールゲゾントヘイト ベー.フェー. | ストレプトコッカス・スイスの環境的に調節された遺伝子 |
USRE47164E1 (en) | 2005-09-02 | 2018-12-18 | Valorisation-Recherche Limited Partnership | Streptococcus suis polypeptides and polynucleotides encoding same and their use in vaccinal and diagnostic applications |
CN100388952C (zh) * | 2006-04-25 | 2008-05-21 | 范红结 | 一种链球菌重组亚单位疫苗及其制备方法 |
CN100449005C (zh) * | 2006-06-29 | 2009-01-07 | 中国检验检疫科学研究院动植物检疫研究所 | 应用于猪链球菌2型致病性检测的多重荧光pcr检测试剂及方法 |
CN100449006C (zh) * | 2006-08-10 | 2009-01-07 | 中国检验检疫科学研究院动植物检疫研究所 | 应用于猪链球菌2型胞外因子(ef)荧光pcr检测的引物和探针序列 |
EP2023143A1 (en) * | 2007-08-06 | 2009-02-11 | Boehringer Ingelheim Vetmedica Gmbh | Immunogenic streptococcus proteins |
CN101613402B (zh) * | 2008-06-25 | 2012-11-28 | 中国人民解放军军事医学科学院微生物流行病研究所 | 一种猪链球菌2型表面蛋白、其制备方法及用途 |
CN101613400B (zh) * | 2008-06-25 | 2012-11-28 | 中国人民解放军军事医学科学院微生物流行病研究所 | 一种猪链球菌2型表面细胞壁蛋白、其制备方法及用途 |
CN101613399B (zh) * | 2008-06-25 | 2012-11-28 | 中国人民解放军军事医学科学院微生物流行病研究所 | 一种猪链球菌2型表面蛋白、其制备方法及用途 |
MX2015013142A (es) * | 2013-03-15 | 2016-05-18 | Camas Inc | Métodos y composiciones para reducir microorganismos en la orofaringe, nasofaringe y cavidades orales. |
CN104762244B (zh) * | 2015-02-04 | 2017-09-15 | 中国农业科学院哈尔滨兽医研究所 | 猪链球菌SBP_bac_5基因缺失株及其构建方法与应用 |
CN107805660B (zh) * | 2017-12-08 | 2021-11-26 | 江汉大学 | 一种猪链球菌小种分离鉴定方法 |
GB2587228B (en) * | 2019-09-20 | 2021-10-27 | Protein Ark Ltd | Biological sample purification apparatus, use of the same, and systems comprising the same |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4784948A (en) * | 1983-08-10 | 1988-11-15 | The Rockefeller University | Production of streptococcal m protein immunogens and molecular probes |
CA2009708A1 (en) * | 1989-02-13 | 1990-08-13 | Jane D. Madonna | Nucleic acid probe for the detection of salmonella human pathogens |
-
1991
- 1991-03-21 NL NL9100510A patent/NL9100510A/nl not_active Application Discontinuation
-
1992
- 1992-03-18 NZ NZ242037A patent/NZ242037A/en not_active IP Right Cessation
- 1992-03-19 WO PCT/NL1992/000054 patent/WO1992016630A1/en active IP Right Grant
- 1992-03-19 ES ES92908242T patent/ES2094907T3/es not_active Expired - Lifetime
- 1992-03-19 DE DE69214277T patent/DE69214277T2/de not_active Expired - Fee Related
- 1992-03-19 US US08/119,125 patent/US5610011A/en not_active Expired - Lifetime
- 1992-03-19 JP JP4507787A patent/JP2776633B2/ja not_active Expired - Fee Related
- 1992-03-19 AU AU15464/92A patent/AU659637B2/en not_active Ceased
- 1992-03-19 AT AT92908242T patent/ATE143693T1/de not_active IP Right Cessation
- 1992-03-19 DK DK92908242.8T patent/DK0575497T3/da active
- 1992-03-19 EP EP92908242A patent/EP0575497B1/en not_active Expired - Lifetime
- 1992-03-19 CA CA002105057A patent/CA2105057C/en not_active Expired - Fee Related
- 1992-03-21 CN CN92101913A patent/CN1055500C/zh not_active Expired - Fee Related
-
1996
- 1996-12-17 GR GR960403484T patent/GR3022052T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69214277T2 (de) | 1997-03-20 |
AU659637B2 (en) | 1995-05-25 |
CN1065490A (zh) | 1992-10-21 |
EP0575497B1 (en) | 1996-10-02 |
NZ242037A (en) | 1997-03-24 |
DE69214277D1 (de) | 1996-11-07 |
ATE143693T1 (de) | 1996-10-15 |
EP0575497A1 (en) | 1993-12-29 |
AU1546492A (en) | 1992-10-21 |
GR3022052T3 (en) | 1997-03-31 |
DK0575497T3 (da) | 1996-11-18 |
CA2105057A1 (en) | 1992-09-22 |
US5610011A (en) | 1997-03-11 |
CA2105057C (en) | 2000-05-02 |
CN1055500C (zh) | 2000-08-16 |
WO1992016630A1 (en) | 1992-10-01 |
JPH06505390A (ja) | 1994-06-23 |
JP2776633B2 (ja) | 1998-07-16 |
NL9100510A (nl) | 1992-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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