DE69122103D1 - Antigerinnungspeptide - Google Patents

Antigerinnungspeptide

Info

Publication number
DE69122103D1
DE69122103D1 DE69122103T DE69122103T DE69122103D1 DE 69122103 D1 DE69122103 D1 DE 69122103D1 DE 69122103 T DE69122103 T DE 69122103T DE 69122103 T DE69122103 T DE 69122103T DE 69122103 D1 DE69122103 D1 DE 69122103D1
Authority
DE
Germany
Prior art keywords
peptides
guard
relates
peptide derivatives
anticoagulant agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69122103T
Other languages
English (en)
Other versions
DE69122103T2 (de
Inventor
John Krstenansky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69122103D1 publication Critical patent/DE69122103D1/de
Publication of DE69122103T2 publication Critical patent/DE69122103T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
DE69122103T 1990-07-24 1991-06-28 Antigerinnungspeptide Expired - Fee Related DE69122103T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55728890A 1990-07-24 1990-07-24
PCT/US1991/004658 WO1992001710A1 (en) 1990-07-24 1991-06-28 Anticoagulant peptides

Publications (2)

Publication Number Publication Date
DE69122103D1 true DE69122103D1 (de) 1996-10-17
DE69122103T2 DE69122103T2 (de) 1997-02-13

Family

ID=24224803

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69122103T Expired - Fee Related DE69122103T2 (de) 1990-07-24 1991-06-28 Antigerinnungspeptide

Country Status (15)

Country Link
US (1) US5495000A (de)
EP (1) EP0540574B1 (de)
JP (1) JP3111075B2 (de)
KR (1) KR100195424B1 (de)
AT (1) ATE142648T1 (de)
AU (1) AU648096B2 (de)
CA (1) CA2086243C (de)
DE (1) DE69122103T2 (de)
DK (1) DK0540574T3 (de)
ES (1) ES2094228T3 (de)
FI (1) FI930265A0 (de)
GR (1) GR3021660T3 (de)
HU (1) HUT63180A (de)
NO (1) NO930234L (de)
WO (1) WO1992001710A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2605586B2 (ja) * 1992-07-24 1997-04-30 トヨタ自動車株式会社 内燃機関の排気浄化装置
US7109326B2 (en) 1997-04-15 2006-09-19 Genentech, Inc. Halo-alkoxycarbonyl prodrugs
CA2623565A1 (en) 2005-09-28 2007-04-05 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
CN103520160B (zh) * 2013-10-17 2015-04-22 广东药学院 三棱中肽类化合物的应用
WO2020111331A1 (ko) * 2018-11-29 2020-06-04 글라드아이 주식회사 음료용기
KR102152140B1 (ko) * 2019-10-21 2020-09-04 글라드아이 주식회사 음료용기
CN112430254B (zh) * 2020-11-25 2021-10-26 广东海洋大学 一种抗凝血活性肽衍生物及其制备方法和用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792525A (en) * 1982-08-04 1988-12-20 La Jolla Cancer Research Foundation Tetrapeptide
DE3438296A1 (de) * 1984-04-18 1985-11-07 Hoechst Ag, 6230 Frankfurt Neue polypeptide mit blutgerinnungshemmender wirkung, verfahren zu deren herstellung bzw. gewinnung, deren verwendung und diese enthaltende mittel
DE3445532A1 (de) * 1984-12-13 1986-06-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn Hirudin-pa, desulfatohirudine-pa, verfahren zur herstellung und pharmazeutische mittel, die diese wirkstoffe enthalten
CA1341032C (en) * 1987-01-23 2000-06-20 John L. Krstenansky Anticoagulant peptides
AU3098289A (en) * 1988-03-04 1989-09-07 Biogen, Inc. Hirudin peptides
FR2628429B1 (fr) * 1988-03-08 1990-12-28 Transgene Sa Variants de l'hirudine, leurs utilisations et les procedes pour les obtenir
NZ228995A (en) * 1988-05-10 1992-03-26 Merrell Dow Pharma Hirudin peptide derivatives and pharmaceutical compositions
ES2052062T3 (es) * 1988-06-11 1994-07-01 Ciba Geigy Ag Nuevos polipeptidos con actividad anticoagulante.
IT217993Z2 (it) * 1988-12-15 1992-03-05 Faccia Tiziano Agitatore-miscelatore per impianti di biogas
ZA907742B (en) * 1989-10-03 1991-07-31 Merrell Dow Pharma Anticoagulant peptides
CA2026377A1 (en) * 1989-10-03 1991-04-04 John L. Krstenansky Radiolabeled anticoagulant peptides
JP2669510B2 (ja) * 1990-06-15 1997-10-29 ナショナル・リサーチ・カウンシル・オブ カナダ ヒルジンのアミノ酸配列に基づくトロンビン阻害剤
IT1243358B (it) * 1990-07-23 1994-06-10 Iketon Farmaceutici Srl Composizioni farmaceutiche per la somministrazione orale di irudina
US5118790A (en) * 1990-07-24 1992-06-02 Sri International Analogs of hirudin
ZA915658B (en) * 1990-07-24 1992-05-27 Merrell Dow Pharma Analogs of hirudin having antiplatelet activity

Also Published As

Publication number Publication date
DK0540574T3 (da) 1996-09-30
GR3021660T3 (en) 1997-02-28
ATE142648T1 (de) 1996-09-15
FI930265A (fi) 1993-01-22
ES2094228T3 (es) 1997-01-16
KR100195424B1 (ko) 1999-06-15
NO930234D0 (no) 1993-01-22
CA2086243A1 (en) 1992-01-25
WO1992001710A1 (en) 1992-02-06
EP0540574B1 (de) 1996-09-11
AU648096B2 (en) 1994-04-14
FI930265A0 (fi) 1993-01-22
HU9300191D0 (en) 1993-04-28
HUT63180A (en) 1993-07-28
EP0540574A4 (de) 1994-04-27
NO930234L (no) 1993-01-22
EP0540574A1 (de) 1993-05-12
DE69122103T2 (de) 1997-02-13
JPH05508850A (ja) 1993-12-09
JP3111075B2 (ja) 2000-11-20
US5495000A (en) 1996-02-27
CA2086243C (en) 2001-10-02
AU8221091A (en) 1992-02-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee